Methotrexate combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pustular Psoriasis Other Serious 4/1/2005 Female 128 lb 1/27/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2005 Female 155 lb 3/1/2006 Consumer United States
Primary
Concomitant
Sedation Hospitalization 6/16/2003 49 Female 231 lb 3/23/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2005 Female 254 lb 6/6/2006 Consumer United States
Primary
Concomitant
Somnolence 1/1/2005 42 Female 257 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 144 lb 12/29/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Hospitalization 1/1/2005 45 Female 140 lb 4/23/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 7/6/2007 Female 8/14/2007 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 11/1/2007 Female 12/7/2007 Physician United States
Primary
Concomitant
Weight Increased Female 12/8/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 11/1/2007 Female 204 lb 12/27/2007 Physician United States
Primary
Concomitant
Temporomandibular Joint Syndrome Other Serious 1/1/2000 36 Female 1/18/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 1/22/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 3/14/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 3/18/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 84 lb 3/21/2008 Consumer United States
Primary
Concomitant
Ovarian Cyst 3/21/2008 Female 206 lb 3/24/2008 Other Health Professional United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 5/23/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/9/2007 Female 110 lb 6/3/2008 United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 6/16/2005 Female 225 lb 6/10/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/1/2008 73 Female 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/1/2008 73 Female 6/19/2008 Physician United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Muscle Spasms 5/1/2008 58 Female 240 lb 6/30/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Disorder Other Serious 2/1/2008 37 Female 181 lb 7/8/2008 Physician United Kingdom
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 157 lb 7/17/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/1/2008 Female 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/24/1999 36 Female 157 lb 7/23/2008 Physician United States
Primary
Concomitant
Muscle Spasms 5/15/2008 58 Female 240 lb 9/25/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased 11/1/2007 63 Female 154 lb 9/25/2008 Consumer United States
Primary
Concomitant
Homicidal Ideation Other Serious 9/26/2007 59 Female 9/29/2008 Other Health Professional Australia
Primary
Concomitant
Drug Level Below Therapeutic Other Serious 7/25/2008 Female 149 lb 10/24/2008 Physician United States
Primary
Secondary
Concomitant
Gingivitis Other Serious 9/26/2008 Female 10/24/2008 Physician United Kingdom
Primary
Concomitant
Wound Infection Hospitalization Female 10/22/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 Female 138 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Menorrhagia 3/29/2008 Female 129 lb 12/9/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Cough 9/12/2008 Female 150 lb 12/12/2008 United States
Primary
Concomitant
Paraesthesia 10/1/2007 Female 12/17/2008 Consumer United States
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Syncope Life Threatening 7/2/2008 63 Female 1/26/2009 Pharmacist United States
Primary
Concomitant
Vision Blurred 3/25/2008 40 Female 2/27/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/21/2009 Male 190 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 6/11/2009 Consumer United States
Primary
Concomitant
Injection Site Irritation 3/1/2008 Female 140 lb 6/12/2009 Consumer United States
Primary
Concomitant
Pain 4/1/2009 Female 6/12/2009 United States
Primary
Concomitant
Swelling 1/1/2009 Female 130 lb 6/12/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 53 Female 145 lb 7/14/2009 United States
Primary
Concomitant
Rubella Other Serious 9/26/2008 Female 7/21/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2003 Female 141 lb 8/7/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 Female 141 lb 8/11/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 Female 141 lb 8/21/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 Female 141 lb 9/8/2009 Physician United States
Primary
Concomitant
Injection Site Extravasation 8/23/2008 Female 130 lb 9/12/2009 Consumer United States
Primary
Concomitant
Alopecia 1/1/2009 Female 145 lb 9/19/2009 Consumer United States
Primary
Concomitant
Sinus Disorder 6/26/2009 Female 132 lb 9/19/2009 Consumer United States
Primary
Concomitant
Injection Site Swelling 8/13/2009 Female 128 lb 9/19/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 Female 141 lb 9/28/2009 Physician
Primary
Concomitant
Presyncope Hospitalization 8/21/2009 35 Female 94 lb 9/25/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 Female 141 lb 10/20/2009 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 3/1/2005 44 Female 351 lb 10/21/2009 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 1/1/2008 Female 12/2/2009 Physician United States
Primary
Concomitant
Skin Infection 3/30/2008 Female 217 lb 12/8/2009 Physician United States
Primary
Concomitant
Injection Site Pain 12/1/2008 Female 192 lb 12/9/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/6/2009 Female 109 lb 12/28/2009 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 10/1/2009 15 Female 74 lb 1/20/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 Female 141 lb 1/21/2010 Physician United States
Primary
Concomitant
Tonsillitis 5/1/2009 29 Female 1/24/2010 Consumer United States
Primary
Concomitant
Injection Site Pain Female 197 lb 1/29/2010 United States
Primary
Concomitant
Weight Decreased 10/1/2009 Female 96 lb 1/30/2010 Other Health Professional United States
Primary
Concomitant
Epicondylitis 9/4/2009 Female 127 lb 1/30/2010 United States
Primary
Concomitant
Injection Site Pain 11/9/2009 Female 190 lb 1/30/2010 United States
Primary
Concomitant
Pain 12/9/2009 Female 190 lb 1/30/2010 United States
Primary
Concomitant
Endometrial Cancer Stage Ii Life Threatening 4/29/2008 Female 199 lb 3/11/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/6/2009 Female 109 lb 3/25/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2003 39 Female 130 lb 4/5/2010 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 3/13/2009 37 Female 5/7/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Other Serious 4/6/2010 32 Female 5/21/2010 Brazil
Primary
Concomitant
Vomiting Other Serious 1/1/2003 32 Female 141 lb 5/24/2010 Physician United States
Primary
Concomitant
Hepatotoxicity Other Serious 3 Male 24 lb 5/31/2010 Physician Turkey
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 6/4/2010 Physician United States
Primary
Concomitant
Urine Odour Abnormal 1/1/2008 53 Female 6/23/2010 Consumer United States
Primary
Concomitant
Spinal Meningeal Cyst Other Serious 4/1/2010 48 Female 140 lb 6/30/2010 Physician United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2008 58 Female 145 lb 7/2/2010 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2010 55 Female 153 lb 6/21/2010 United States
Primary
Concomitant
Insomnia 1/1/2008 41 Female 132 lb 7/17/2010 Consumer United States
Primary
Concomitant
Tuberculin Test Positive Other Serious 11/1/2009 42 Male 220 lb 7/20/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting 5/1/2008 34 Female 220 lb 7/22/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2010 32 Female 7/27/2010 Brazil
Primary
Concomitant
Weight Increased Female 168 lb 8/3/2010 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 51 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2010 32 Female 8/16/2010 Brazil
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 8/17/2010 Physician United States
Primary
Concomitant
Tuberculin Test Positive Other Serious 11/1/2009 42 Male 220 lb 8/18/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2010 32 Female 8/23/2010 Brazil
Primary
Concomitant
Vomiting Other Serious 1/1/2010 32 Female 9/1/2010 Brazil
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2009 40 Female 180 lb 9/10/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 9/21/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 9/22/2010 Physician United States
Primary
Concomitant
Subclavian Vein Thrombosis Other Serious 2/27/2009 21 Female 190 lb 10/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Other Serious 2/27/2009 21 Female 190 lb 10/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 10/13/2010 Other Health Professional
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 10/14/2010 Other Health Professional
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 10/25/2010 38 Male 240 lb 11/22/2010 Consumer United States
Primary
Concomitant
Thermal Burn Other Serious 6/1/2010 38 Male 250 lb 12/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/27/2009 20 Female 190 lb 1/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Cholesterosis Other Serious 5/20/2008 25 Female 1/17/2011 Lawyer United States
Primary
Concomitant
Anaemia Other Serious 12/11/2010 60 Female 222 lb 1/19/2011 Consumer United States
Primary
Concomitant
Pain 1/1/2009 50 Female 196 lb 1/28/2011 United States
Primary
Secondary
Concomitant
Tinea Pedis 10/1/2009 57 Female 158 lb 1/28/2011 Consumer United States
Primary
Concomitant
Headache 2/11/2010 62 Female 140 lb 1/28/2011 United States
Primary
Concomitant
Headache 2/5/2003 54 Female 306 lb 1/28/2011 United States
Primary
Concomitant
Dizziness 11/1/2009 40 Female 1/29/2011 Consumer United States
Primary
Concomitant
Mobility Decreased 4/29/2010 Female 1/29/2011 Consumer United States
Primary
Concomitant
Pain 8/10/2010 44 Female 1/29/2011 Consumer United States
Primary
Concomitant
Joint Swelling Female 180 lb 1/29/2011 Consumer United States
Primary
Concomitant
Streptococcal Infection 1/1/2010 46 Female 160 lb 1/29/2011 Physician United States
Primary
Concomitant
Joint Swelling 1/1/2008 46 Female 227 lb 1/29/2011 Consumer United States
Primary
Concomitant
Hypoaesthesia Facial 7/17/2010 18 Male 150 lb 1/29/2011 Physician United States
Primary
Concomitant
Breast Cancer Hospitalization 2/1/2005 55 Female 159 lb 1/29/2011 Consumer United States
Primary
Concomitant
Hypoaesthesia 7/28/2010 40 Female 1/29/2011 Consumer United States
Primary
Concomitant
Pain 12/9/2009 40 Female 190 lb 1/29/2011 Consumer United States
Primary
Concomitant
Spinal Disorder 10/1/2007 37 Female 1/29/2011 Consumer United States
Primary
Concomitant
Diarrhoea 9/2/2010 53 Female 125 lb 1/29/2011 Consumer United States
Primary
Concomitant
Urticaria 9/1/2010 24 Female 1/30/2011 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/1/2010 46 Female 1/30/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 10/15/2010 11 Male 1/30/2011 Consumer United States
Primary
Concomitant
Rib Fracture Hospitalization 6/20/2010 49 Female 2/4/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 6/1/2010 38 Male 250 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Eating Disorder Hospitalization 1/1/2010 49 Female 150 lb 2/17/2011 Consumer Brazil
Primary
Concomitant
Pain In Extremity Other Serious 5/20/2008 25 Female 178 lb 3/10/2011 Consumer United States
Primary
Concomitant
Pain Female 126 lb 3/18/2011 Consumer United States
Primary
Concomitant
Asthenia Other Serious 2/14/2011 68 Female 3/18/2011 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2010 55 Female 172 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Haematoma Hospitalization 12/27/2010 62 Female 114 lb 5/13/2011 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 2/21/2011 47 Female 5/24/2011 Consumer Canada
Primary
Concomitant
Eating Disorder Hospitalization 1/1/2010 49 Female 150 lb 5/26/2011 Consumer Brazil
Primary
Concomitant
Suicidal Ideation Other Serious 6/1/2010 39 Male 250 lb 3/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/1/2010 45 Female 5/31/2011 Consumer United States
Primary
Secondary
Concomitant
Abdominal Pain 11/1/2010 45 Female 150 lb 5/11/2011 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 47 Female 166 lb 7/29/2011 Consumer United States
Primary
Concomitant
Dysgeusia Other Serious 1/1/2007 47 Female 166 lb 8/22/2011 Physician United States
Primary
Concomitant
Peroneal Nerve Palsy Hospitalization 9/1/2010 25 Female 250 lb 8/31/2011 Consumer United States
Primary
Concomitant
Somnolence Other Serious 8/1/2008 56 Female 141 lb 9/6/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 8/1/2008 56 Female 141 lb 9/14/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 1/1/2011 46 Female 254 lb 9/19/2011 Consumer United States
Primary
Concomitant
Interacting

Drug Data