Methotrexate combined with Platelets

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Death 6/11/2006 Male 6/29/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 8/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 8/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 1/1/2004 30 Female 10/11/2006 Other Health Professional India
Primary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 4/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9 Male 11/14/2007
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/13/2006 74 Male 198 lb 4/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Systemic Candida Other Serious 11/5/2007 38 Male 5/5/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/21/2007 25 Male 112 lb 6/4/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/21/2007 25 Male 112 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 11/1/2007 38 Male 7/8/2008 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 7/28/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious Male 10/17/2008 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 8/3/2007 24 Male 126 lb 10/20/2008 Consumer Japan
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/1/2007 60 Male 143 lb 12/16/2008 Physician Spain
Primary
Secondary
Concomitant
Venoocclusive Disease Death 8/7/2008 Female 12/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/1/2007 60 Male 143 lb 12/19/2008 Physician Spain
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 12/21/2008 4 Male 44 lb 1/7/2009 Physician Germany
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/21/2008 4 Male 44 lb 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Clostridium Difficile Colitis 22 Female 2/19/2009 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 10/3/2008 60 Female 106 lb 3/12/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/20/2008 45 Male 128 lb 3/12/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 57 Male 3/18/2009
Primary
Concomitant
Skin Ulcer Other Serious 68 Male 3/18/2009
Primary
Concomitant
Renal Impairment Life Threatening 6/26/2008 49 4/6/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 6/20/2008 62 Female 108 lb 4/27/2009 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 6/24/2008 44 Female 93 lb 5/8/2009 Other Health Professional Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/22/2009 61 Female 143 lb 5/11/2009 Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 7/25/2008 61 Male 146 lb 5/11/2009 Japan
Primary
Concomitant
Acute Graft Versus Host Disease Hospitalization 11/16/2008 41 Male 128 lb 5/11/2009 Japan
Primary
Concomitant
Cytomegalovirus Viraemia Other Serious 7/4/2008 65 Male 146 lb 5/11/2009 Japan
Primary
Concomitant
Cytomegalovirus Viraemia Other Serious 10/13/2008 50 Female 93 lb 5/11/2009 Japan
Primary
Concomitant
Sepsis Other Serious 8/11/2008 37 Female 99 lb 5/11/2009 Japan
Primary
Concomitant
Sepsis Other Serious 9/21/2008 30 Female 117 lb 5/11/2009 Japan
Primary
Concomitant
Sepsis Hospitalization 6/24/2008 44 Female 93 lb 5/12/2009 Other Health Professional Japan
Primary
Concomitant
Acute Graft Versus Host Disease Hospitalization 11/16/2008 41 Male 128 lb 5/12/2009 Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/22/2009 61 Female 143 lb 5/12/2009 Japan
Primary
Concomitant
Sepsis Other Serious 8/11/2008 37 Female 99 lb 5/12/2009 Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 7/25/2008 61 Male 146 lb 5/12/2009 Japan
Primary
Concomitant
Cytomegalovirus Viraemia Other Serious 7/4/2008 65 Male 146 lb 5/12/2009 Japan
Primary
Concomitant
Cytomegalovirus Viraemia Other Serious 10/13/2008 50 Female 93 lb 5/12/2009 Japan
Primary
Concomitant
Sepsis Other Serious 9/21/2008 30 Female 117 lb 5/12/2009 Japan
Primary
Concomitant
Sepsis Other Serious 12/22/2008 43 Female 97 lb 5/12/2009 Other Health Professional Japan
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 10/29/2008 60 Female 148 lb 5/14/2009 Japan
Primary
Concomitant
Engraft Failure Death 11/20/2008 57 Female 104 lb 5/15/2009 Japan
Primary
Concomitant
Pneumonia Other Serious 7/31/2008 62 Male 165 lb 5/18/2009 Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/2/2008 56 Male 108 lb 5/18/2009 Japan
Primary
Concomitant
Multi-organ Failure Hospitalization Female 196 lb 5/18/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 10/10/2008 56 Male 121 lb 5/20/2009 Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/10/2008 56 Male 121 lb 5/21/2009 Japan
Primary
Secondary
Concomitant
Sepsis Death 9/18/2008 64 Male 117 lb 5/26/2009 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 1/30/2009 42 Male 139 lb 5/28/2009 Japan
Primary
Concomitant
Cytomegalovirus Viraemia Other Serious 10/27/2008 49 Male 115 lb 5/28/2009 Japan
Primary
Concomitant
Pyrexia Other Serious 1/16/2009 53 Male 112 lb 5/28/2009 Japan
Primary
Concomitant
Stomatitis Other Serious 9/17/2008 56 Male 139 lb 5/28/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 12/19/2008 59 Male 123 lb 5/28/2009 Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Other Serious 3/12/2009 61 Male 117 lb 5/29/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 5/26/2009 Female 152 lb 5/28/2009 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/1/2008 57 Male 108 lb 6/5/2009 Japan
Primary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 9/26/2008 46 Male 123 lb 6/5/2009 Physician Jordan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 9/26/2008 46 Male 123 lb 6/8/2009 Physician Jordan
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 12/15/2008 Female 196 lb 6/8/2009 Physician United Kingdom
Primary
Concomitant
Nausea Other Serious 10/27/2008 58 Female 106 lb 6/9/2009 Physician Japan
Primary
Secondary
Concomitant
Systemic Mycosis Other Serious 12/9/2008 25 Female 99 lb 6/9/2009 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 2/2/2009 59 Female 88 lb 6/9/2009 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 2/10/2009 39 Male 150 lb 6/9/2009 Japan
Primary
Concomitant
Vomiting Other Serious 3/1/2008 6 Male 60 lb 6/5/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 2/2/2009 60 Male 157 lb 6/12/2009 Japan
Primary
Secondary
Concomitant
Bone Marrow Transplant Other Serious 3/1/2009 37 Male 99 lb 6/17/2009 Physician Japan
Primary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 6/26/2009 Physician Germany
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2008 7 Female 7/13/2009 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 3/1/2008 6 Male 60 lb 7/31/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 50 Male 9/4/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/9/2008 25 Female 99 lb 9/8/2009 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 10/29/2008 58 Female 106 lb 9/8/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 7/2/2008 49 Male 141 lb 9/11/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 50 Male 9/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/2/2008 56 Male 108 lb 9/15/2009 Japan
Primary
Concomitant
Pneumonia Other Serious 10/3/2008 56 Male 121 lb 9/15/2009 Japan
Primary
Secondary
Concomitant
Nausea Other Serious 10/29/2008 58 Female 106 lb 9/15/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/18/2008 26 Female 117 lb 9/15/2009 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Other Serious 2/2/2009 59 Female 88 lb 9/17/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 9/21/2008 30 Female 117 lb 9/18/2009 Japan
Primary
Concomitant
Weight Increased Other Serious 12/9/2008 25 Female 99 lb 9/24/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 6/20/2008 62 Female 108 lb 9/24/2009 Physician Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 9/24/2008 57 Female 104 lb 9/25/2009 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 7/2/2008 49 Male 141 lb 9/25/2009 Physician Japan
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 8/25/2008 18 Male 128 lb 10/1/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 6/4/2008 62 Male 154 lb 10/7/2009 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2008 7 Female 10/15/2009 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 9/18/2008 64 Male 117 lb 11/2/2009 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 6/4/2008 62 Male 154 lb 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/2/2009 60 Male 157 lb 11/23/2009 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/30/2009 15 Male 12/8/2009 Other Health Professional Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 9 1/8/2010
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/3/2007 Male 126 lb 2/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 6/30/2009 15 Male 2/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/25/2008 39 Male 157 lb 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/30/2009 15 Male 2/18/2010 Physician Japan
Primary
Secondary
Concomitant
Transfusion-related Acute Lung Injury Hospitalization 3/1/2009 49 Female 3/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/25/2008 39 Male 157 lb 3/22/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/30/2009 15 Male 88 lb 4/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/30/2009 15 Male 88 lb 4/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/24/2009 15 Male 88 lb 5/3/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/27/2010 52 Female 110 lb 10/29/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Premature Baby Hospitalization 12/25/2003 Female 4 lb 1/18/2011 Physician France
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Pneumonia Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Cardiac Arrest Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Haemolytic Anaemia Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Venoocclusive Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Sudden Death Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Parainfluenzae Virus Infection Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Infection Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Encephalopathy Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Cardiac Arrest Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Cardiac Arrest Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Pseudomonal Sepsis Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Blood Stem Cell Transplant Failure Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Cardiac Failure Death 3/7/2011 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 1/26/2011 81 Female 129 lb 4/21/2011 Physician Japan
Primary
Concomitant
Emotional Distress Other Serious 9/23/2005 59 Male 212 lb 5/13/2011 Other Health Professional United States
Primary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant
Candida Test Positive Hospitalization 3/12/2010 54 Female 95 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Injury Hospitalization 3/3/2004 67 Male 196 lb 6/10/2011 Other Health Professional United States
Primary
Concomitant
Injection Site Erythema Other Serious 2/16/2009 84 Male 6/28/2011 Austria
Primary
Concomitant
Memory Impairment Hospitalization 2/10/2010 23 Male 117 lb 7/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stress Other Serious 10/12/2004 54 Male 203 lb 7/15/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Hospitalization 10/12/2004 54 Male 203 lb 8/3/2011 Consumer United States
Primary
Concomitant
Multi-organ Failure Death 11/7/2010 51 Male 137 lb 8/4/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 61 Male 8/18/2011 Other Health Professional Sweden
Primary
Concomitant
Anxiety Other Serious 10/12/2004 54 Male 203 lb 8/24/2011 Lawyer United States
Primary
Concomitant

Drug Data