Folacin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Adverse Event Other Serious 11/11/2005 68 Female 1/10/2006 Physician Sweden
Primary
Concomitant
Adverse Event Other Serious 8/3/2005 68 Female 1/25/2006 Physician Sweden
Primary
Concomitant
Pancreatic Disorder Hospitalization 12/1/2004 63 Female 2/6/2006 Sweden
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2005 40 Female 2/13/2006 Other Health Professional Sweden
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 51 Female 2/16/2006 Physician Sweden
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 Male 2/17/2006 Consumer Sweden
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/3/2005 68 Female 3/9/2006 Physician Sweden
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Female 3/21/2006 Physician Sweden
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 Female 3/28/2006 Physician Sweden
Primary
Secondary
Concomitant
Pancreatic Disorder Hospitalization 12/1/2004 Female 4/21/2006 Physician Sweden
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 9/1/2004 74 Female 4/28/2006 Physician Sweden
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 9/1/2004 74 Female 4/28/2006 Physician Sweden
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/2003 Male 5/17/2006 Physician Sweden
Primary
Concomitant
Urticaria Other Serious 1/1/2003 Male 5/23/2006 Physician Sweden
Primary
Concomitant
Septic Shock Other Serious 11/11/2005 68 Female 6/15/2006 Physician Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2005 71 Male 6/19/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 4/16/2006 53 Female 8/14/2006 Other Health Professional Sweden
Primary
Concomitant
Fallopian Tube Cancer Hospitalization 9/21/2005 50 Female 8/22/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Synovial Rupture Hospitalization 4/20/2006 71 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Synovial Rupture Hospitalization 4/20/2006 71 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Hyperglycaemia Hospitalization 9/15/2006 Female 130 lb 10/3/2006 Physician Sweden
Primary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 6/1/2005 Female 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Infection Hospitalization 9/15/2006 Female 130 lb 10/13/2006 Physician Sweden
Primary
Concomitant
Breast Cancer Other Serious 8/1/2006 71 Female 11/8/2006 Physician Sweden
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 61 Female 11/8/2006 Physician Sweden
Primary
Concomitant
Transverse Sinus Thrombosis Hospitalization 1/1/2005 39 Female 11/8/2006 Physician Sweden
Primary
Concomitant
Unevaluable Event Hospitalization 11/21/2005 32 Female 11/17/2006 Other Health Professional Sweden
Primary
Concomitant
Uveitis Hospitalization 1/1/2005 39 Female 12/6/2006 Physician Sweden
Primary
Concomitant
Renal Pain Hospitalization 6/27/2006 58 Female 12/22/2006 Physician Sweden
Primary
Concomitant
Renal Tubular Necrosis Life Threatening 3/15/2004 Female 1/26/2007 Physician Sweden
Primary
Concomitant
Syncope Other Serious 2/1/2005 48 Male 1/27/2007 Other Health Professional Sweden
Primary
Concomitant
Nausea Hospitalization 3/17/2006 34 Female 2/16/2007 Physician Sweden
Primary
Concomitant
Nervous System Disorder Disability 1/1/2005 55 Female 2/16/2007 Physician Sweden
Primary
Concomitant
Sepsis Life Threatening 2/3/2006 76 Female 2/16/2007 Physician Sweden
Primary
Concomitant
Pancytopenia Hospitalization 10/25/2006 87 Male 3/2/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 12/1/2005 Female 3/21/2007 Physician Sweden
Primary
Concomitant
B-cell Lymphoma Other Serious 11/1/2005 58 Female 3/27/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 1/27/2003 Female 5/1/2007 Other Health Professional Sweden
Primary
Concomitant
Parkinson's Disease Other Serious 5/1/2005 55 Female 5/22/2007 Other Health Professional Sweden
Primary
Concomitant
Prostate Cancer Other Serious 3/7/2007 65 Male 5/25/2007 Physician Sweden
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 10/1/2006 43 Female 6/19/2007 Physician Sweden
Primary
Concomitant
Postoperative Wound Infection Hospitalization 3/24/2006 68 Male 6/28/2007 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Other Serious 8/20/2006 70 Female 6/29/2007 Other Health Professional Sweden
Primary
Concomitant
Suicide Attempt Hospitalization 10/13/2006 57 Female 7/17/2007 Other Health Professional Sweden
Primary
Concomitant
Renal Tubular Necrosis Life Threatening 3/15/2004 Female 7/18/2007 Physician Sweden
Primary
Concomitant
Postoperative Wound Infection Hospitalization 3/24/2006 68 Male 7/18/2007 Other Health Professional Sweden
Primary
Concomitant
Vomiting Other Serious 1/1/2005 61 Female 7/20/2007 Physician Sweden
Primary
Concomitant
Pneumonia Hospitalization 10/23/2006 87 Male 7/20/2007 Physician Sweden
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 12/1/2004 62 Female 7/20/2007 Physician Sweden
Primary
Secondary
Concomitant
Syncope Other Serious 2/1/2005 Male 8/13/2007 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Other Serious 8/20/2006 Female 8/14/2007 Other Health Professional Sweden
Primary
Concomitant
Postoperative Wound Infection Hospitalization 3/24/2006 Male 8/14/2007 Other Health Professional Sweden
Primary
Concomitant
Pyrexia Hospitalization 12/1/2003 Female 8/16/2007 Other Health Professional Sweden
Primary
Concomitant
Tuberculosis Life Threatening 9/1/2005 Male 8/16/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2005 Female 8/17/2007 Other Health Professional Sweden
Primary
Concomitant
Respiratory Failure Hospitalization 1/1/2004 Male 8/28/2007 Physician Sweden
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 9/28/2007 Other Health Professional Sweden
Primary
Concomitant
Vomiting Other Serious 1/1/2005 48 Female 179 lb 10/1/2007 Physician Sweden
Primary
Concomitant
Sensory Disturbance Other Serious 10/18/2007 18 Female 1/24/2008 Other Health Professional Sweden
Primary
Concomitant
Pneumonia Legionella Hospitalization 2/1/2006 66 Female 1/24/2008 Physician Sweden
Primary
Concomitant
Breast Cancer Female Other Serious 2/1/2006 47 Female 1/24/2008 Physician Sweden
Primary
Concomitant
Pneumonia Hospitalization 1/22/2006 61 Female 1/25/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 8/1/2006 71 Female 1/25/2008 Physician Sweden
Primary
Concomitant
Pleurisy Hospitalization 12/14/2005 63 Female 1/28/2008 Physician Sweden
Primary
Concomitant
Palpitations Hospitalization 3/1/2005 66 Male 1/29/2008 Physician Sweden
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/1/2003 82 Female 1/29/2008 Physician Sweden
Primary
Concomitant
Syncope Other Serious 12/18/2002 50 1/29/2008 Physician Sweden
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/1/1996 40 Female 1/29/2008 Physician Sweden
Primary
Concomitant
Malignant Respiratory Tract Neoplasm Other Serious 12/1/2003 62 Female 1/31/2008 Physician Sweden
Primary
Concomitant
Hemiparesis Hospitalization 12/18/2004 64 Male 2/6/2008 Physician Sweden
Primary
Concomitant
Tuberculin Test Positive Hospitalization 5/1/2004 54 Female 2/8/2008 Physician Sweden
Primary
Concomitant
Sensory Disturbance Other Serious 10/18/2007 18 Female 2/15/2008 Other Health Professional Sweden
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/1/2007 60 Male 3/1/2008 Physician Sweden
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/27/2007 53 Female 3/4/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 12/27/2007 53 Female 3/6/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Urticaria Other Serious 3/25/2008 53 Female 4/7/2008 Other Health Professional Sweden
Primary
Concomitant
Genitourinary Tract Neoplasm Hospitalization 2/9/2007 69 Female 4/11/2008 Physician Sweden
Primary
Concomitant
Genital Neoplasm Malignant Female Other Serious 3/1/2008 Female 5/15/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/7/2008 40 Male 5/20/2008 Physician Sweden
Primary
Concomitant
Rectal Cancer Other Serious 5/31/2006 33 Male 6/9/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Other Serious 4/2/2008 65 Female 7/16/2008 Other Health Professional Sweden
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2005 66 Female 7/16/2008 Physician Sweden
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/1/2007 60 Male 7/16/2008 Physician Sweden
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/8/2007 64 Female 8/18/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Intestinal Functional Disorder Hospitalization 6/4/2007 Female 8/27/2008 Physician Sweden
Primary
Concomitant
Breast Cancer Hospitalization 10/1/2007 67 Female 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 7/17/2008 81 Female 9/5/2008 Other Health Professional Sweden
Primary
Concomitant
Urticaria Other Serious 3/25/2008 53 Female 9/22/2008 Other Health Professional Sweden
Primary
Concomitant
Nausea Other Serious 5/1/2008 57 Male 10/14/2008 Physician Sweden
Primary
Secondary
Concomitant
Breast Cyst Other Serious 6/1/2008 Female 10/22/2008 Consumer Sweden
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 8/1/2008 58 Female 10/23/2008 Other Health Professional Sweden
Primary
Concomitant
Nausea Other Serious 5/1/2008 57 Male 10/27/2008 Physician Sweden
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 12/1/2007 57 Male 10/28/2008 Physician Sweden
Primary
Concomitant
Oesophageal Carcinoma Other Serious 3/19/2007 61 Female 10/29/2008 Other Health Professional Sweden
Primary
Concomitant
Oesophageal Carcinoma Other Serious 3/19/2007 61 Female 10/31/2008 Other Health Professional Sweden
Primary
Concomitant
Nausea Other Serious 5/1/2008 57 Male 11/17/2008 Physician Sweden
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 9/20/2008 73 Male 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 7/4/2007 68 Male 1/23/2009 Physician Sweden
Primary
Concomitant
Prostate Cancer Hospitalization 12/1/2007 57 Male 1/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2008 75 Female 1/26/2009 Physician Sweden
Primary
Secondary
Concomitant
Polycythaemia Hospitalization 4/9/2008 32 Female 1/26/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 7/17/2008 81 Female 2/4/2009 Other Health Professional Sweden
Primary
Concomitant
Breast Cancer Male Hospitalization 11/1/2008 2/6/2009 Other Health Professional Sweden
Primary
Concomitant
Hyperthyroidism Other Serious 9/12/2008 67 Female 2/9/2009 Other Health Professional Sweden
Primary
Concomitant
Vomiting Hospitalization 11/1/2008 75 Female 2/11/2009 Physician Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/14/2008 2/16/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Oesophageal Carcinoma Other Serious 3/19/2007 61 Female 2/18/2009 Other Health Professional Sweden
Primary
Concomitant
Polycythaemia Hospitalization 4/9/2008 32 Female 2/19/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pericarditis Hospitalization 5/7/2008 Male 2/20/2009 Other Health Professional Sweden
Primary
Concomitant
Cerebral Infarction Hospitalization 12/12/2006 64 Male 2/24/2009 Sweden
Primary
Concomitant
Vomiting Hospitalization 11/1/2008 Female 2/26/2009 Physician Sweden
Primary
Secondary
Concomitant
Breast Cancer Metastatic Hospitalization 1/19/2004 50 Female 4/10/2009 Physician Sweden
Primary
Concomitant
Multiple Myeloma Hospitalization 3/10/2009 73 Female 4/10/2009 Physician Sweden
Primary
Concomitant
Vision Blurred Hospitalization 1/26/2009 48 Female 4/29/2009 Other Health Professional Sweden
Primary
Concomitant
Optic Neuritis Other Serious 3/16/2009 Female 5/11/2009 Other Health Professional Sweden
Primary
Concomitant
Prostate Cancer Hospitalization 9/12/2006 59 Male 7/16/2009 Other Health Professional Sweden
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iv Hospitalization 2/1/2002 Male 7/17/2009 Other Health Professional Sweden
Primary
Concomitant
Cardiomyopathy Other Serious 6/28/2009 69 Male 7/24/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Other Serious 6/28/2009 Male 8/26/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/1/2008 Female 9/1/2009 Physician Sweden
Primary
Secondary
Concomitant
Sepsis Other Serious 1/9/2009 75 Female 9/8/2009 Physician Sweden
Primary
Concomitant
Herpes Zoster Infection Neurological Other Serious 6/14/2009 Female 9/24/2009 Physician Sweden
Primary
Concomitant
Pneumocystis Jiroveci Infection Hospitalization Male 9/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vasculitis Cerebral Hospitalization 10/1/2008 Female 10/16/2009 Physician Sweden
Primary
Concomitant
Breast Cancer Metastatic Life Threatening 1/19/2004 50 Female 10/30/2009 Physician Sweden
Primary
Concomitant
Optic Neuritis Other Serious 3/1/2009 Female 10/30/2009 Physician Sweden
Primary
Concomitant
Herpes Zoster Hospitalization 9/14/2009 44 Female 11/12/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Hospitalization Male 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/26/2009 Female 11/24/2009 Other Health Professional Sweden
Primary
Concomitant
Vasculitis Cerebral Hospitalization 10/1/2008 Female 12/14/2009 Physician Sweden
Primary
Concomitant
Urine Output Decreased Life Threatening 9/1/2001 67 Female 12/18/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pericarditis Other Serious 2/24/2003 Male 1/26/2010 Other Health Professional Sweden
Primary
Concomitant
Pericarditis Hospitalization 5/7/2008 Male 1/28/2010 Physician Sweden
Primary
Concomitant
Genital Neoplasm Malignant Female Other Serious 3/1/2008 Female 2/2/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Myalgia Hospitalization 12/12/2009 63 Male 2/16/2010 Other Health Professional Sweden
Primary
Concomitant
Metastatic Uterine Cancer Hospitalization 5/1/2009 68 Female 3/10/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypophosphataemia Hospitalization 3/30/2010 56 Female 218 lb 4/28/2010 Physician Sweden
Primary
Secondary
Concomitant
Alopecia Totalis Other Serious 14 Female 5/3/2010 Consumer Sweden
Primary
Secondary
Concomitant
Genital Neoplasm Malignant Female Hospitalization 12/1/2009 43 Female 5/14/2010 Consumer Sweden
Primary
Secondary
Concomitant
Breast Cancer Female Hospitalization 3/1/2010 53 Female 5/14/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cough Hospitalization 12/1/2009 43 Female 5/14/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Amnesia Hospitalization 3/30/2010 56 Female 218 lb 5/14/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Amnesia Hospitalization 3/30/2010 56 Female 218 lb 5/25/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Amnesia Hospitalization 3/30/2010 56 Female 218 lb 5/27/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 4/1/2010 29 Female 6/1/2010 Physician Sweden
Primary
Concomitant
Respiratory Tract Infection Hospitalization 3/30/2010 57 Female 218 lb 6/1/2010 Physician United States
Primary
Secondary
Concomitant
Amnesia Hospitalization 3/30/2010 56 Female 218 lb 6/14/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/30/2010 57 Female 218 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Amnesia Hospitalization 3/30/2010 56 Female 218 lb 7/7/2010 Sweden
Primary
Secondary
Concomitant
Neoplasm Hospitalization 7/25/2008 61 Female 7/9/2010 Physician United Kingdom
Primary
Concomitant

Drug Data