Famotidine combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Subcutaneous Haematoma Hospitalization 11/25/2005 Male 1/26/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/1/2006 Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization Male 180 lb 2/10/2006 Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/8/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/27/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 3/2/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/2004 68 Male 152 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculin Test Positive Other Serious 11/22/2005 Female 117 lb 4/3/2006 Physician Czech Republic
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 11/18/2005 Male 4/6/2006 Physician Japan
Primary
Concomitant
Ulcer Hospitalization 8/1/2005 Male 154 lb 6/9/2006 Physician United States
Primary
Concomitant
Rash Other Serious 12/4/2003 Female 108 lb 6/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/4/2005 Female 170 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/28/2005 54 Female 106 lb 11/9/2006 Physician Japan
Primary
Concomitant
Retroperitoneal Neoplasm Life Threatening 1/28/2005 54 Female 106 lb 11/20/2006 Physician Japan
Primary
Concomitant
Subdiaphragmatic Abscess Hospitalization 1/1/2004 65 Female 11/13/2006 Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 11/14/2005 Female 88 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 5/21/2004 65 Female 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/14/2005 Female 88 lb 1/19/2007 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 5/15/2004 65 Female 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 60 Male 2/5/2007 Netherlands
Primary
Concomitant
Pneumothorax Hospitalization 5/15/2004 65 Female 2/15/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 8/10/2004 55 Female 5/4/2007 Japan
Primary
Secondary
Renal Impairment Hospitalization 9/30/2005 63 Female 139 lb 6/15/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 7/30/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 8/1/2007 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 6/4/2006 Female 79 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 12/18/2006 20 Male 115 lb 8/2/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 7/27/2007 55 Female 8/13/2007 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 9/27/2005 Female 97 lb 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 7/27/2007 55 Female 9/4/2007 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 10/2/2006 45 Male 143 lb 8/31/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 1/1/2004 Female 178 lb 9/7/2007 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 4/26/2007 10 Male 88 lb 5/29/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 2/1/2007 Female 180 lb 9/21/2007 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/12/2007 70 Male 196 lb 10/1/2007 Physician United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 6/13/2007 65 Female 119 lb 10/10/2007 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 6/13/2007 65 Female 119 lb 10/10/2007 Physician Japan
Primary
Concomitant
Oedema Other Serious 2/21/2005 Male 137 lb 10/18/2007 Physician Japan
Primary
Secondary
Concomitant
Skin Necrosis Other Serious Female 196 lb 10/25/2007 Brazil
Primary
Concomitant
Skin Necrosis Other Serious Female 196 lb 11/1/2007 Brazil
Primary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 11/12/2007 Physician Japan
Primary
Concomitant
Leg Amputation Other Serious 12/26/2003 Male 119 lb 11/20/2007 Physician Japan
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 144 lb 12/6/2007 Physician United States
Primary
Concomitant
Injection Site Pain 4/1/2007 Female 145 lb 12/14/2007 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 6/1/2007 Female 175 lb 12/14/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 Female 178 lb 1/4/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 2/1/2007 Female 132 lb 2/7/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Death 2/9/2006 66 Female 108 lb 2/20/2008 Physician Japan
Primary
Secondary
Concomitant
Eosinophilic Pneumonia Hospitalization 10/2/2007 Male 104 lb 2/29/2008 Physician Japan
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Life Threatening 7/27/2007 55 Female 3/14/2008 Physician Japan
Primary
Concomitant
Somnolence 12/21/2007 Female 172 lb 3/14/2008 Consumer United States
Primary
Concomitant
Eosinophilic Pneumonia Hospitalization 10/2/2007 Male 104 lb 3/20/2008 Physician Japan
Primary
Concomitant
Rash Other Serious 12/4/2003 Female 108 lb 3/21/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/20/2007 68 Female 3/21/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 9/20/2007 68 Female 4/17/2008 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 9/2/2007 Female 123 lb 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 Female 163 lb 4/24/2008 Consumer United States
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 8/1/2006 Female 110 lb 5/30/2008 Physician Japan
Primary
Concomitant
Pneumonia Life Threatening 4/12/2008 Female 101 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Lung Hospitalization 9/20/2007 68 Female 6/9/2008 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 4/22/2008 Female 75 lb 6/12/2008 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Life Threatening 7/20/2007 Female 6/12/2008 Physician Japan
Primary
Secondary
Concomitant
Accidental Exposure 5/30/2008 Female 220 lb 6/13/2008 Consumer United States
Primary
Concomitant
Malaise 5/1/2004 141 lb 6/13/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Biliary Cirrhosis Primary Other Serious 1/23/2006 Female 110 lb 7/2/2008 Physician Japan
Primary
Secondary
Concomitant
Malaise Other Serious 42 Female 130 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 144 lb 8/4/2008 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 143 lb 8/12/2008 Physician United States
Primary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/1/2008 Female 8/27/2008 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 7/28/2008 Female 93 lb 9/5/2008 Physician Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 3/31/2008 54 Male 164 lb 8/26/2008 Physician United States
Primary
Secondary
Concomitant
Virus Serology Test Positive Hospitalization 9/1/2007 Male 180 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Swelling 6/30/2008 Female 160 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 6/1/2008 Female 164 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/1/2008 Female 9/15/2008 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/1/2008 Female 10/2/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 3/31/2008 54 Male 164 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/1/2008 Male 10/30/2008 Physician United States
Primary
Secondary
Concomitant
Dementia Other Serious 1/1/2006 Female 126 lb 11/4/2008 Physician United States
Primary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 11/4/2008 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Female 11/25/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 54 Male 100 lb 11/26/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/3/2007 33 Female 12/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 9/27/2004 70 Female 117 lb 12/10/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 12/27/2007 Female 44 lb 12/5/2008 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis 1/1/2003 Female 254 lb 12/13/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 12/6/2008 Female 18 lb 12/8/2008 United States
Primary
Secondary
Concomitant
Pupil Fixed Hospitalization 12/6/2008 Female 18 lb 12/17/2008 United States
Primary
Secondary
Concomitant
Hypertension Other Serious 1/17/2008 9 Male 88 lb 12/26/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/2/2008 Male 2/9/2009 Physician Japan
Primary
Secondary
Concomitant
Clostridium Difficile Colitis 22 Female 2/19/2009 Other Health Professional United States
Primary
Concomitant
Tendon Rupture Hospitalization 12/25/2008 Female 110 lb 2/19/2009 Japan
Primary
Concomitant
Stomatitis Other Serious 9/15/2008 Male 3/6/2009 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 12/25/2008 Female 110 lb 3/16/2009 Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 1/23/2009 Female 132 lb 4/6/2009 Japan
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 99 lb 4/17/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/17/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/22/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/22/2009 Japan
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 99 lb 4/30/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 5/4/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 6/5/2009 Japan
Primary
Concomitant
Injection Site Swelling 6/30/2008 Female 160 lb 6/11/2009 Consumer United States
Primary
Concomitant
Urticaria 10/1/2008 Female 135 lb 6/12/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2004 75 Female 7/2/2009
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 Female 99 lb 7/6/2009 Physician Japan
Primary
Concomitant
T-cell Lymphoma Hospitalization 7/1/2006 74 Male 7/8/2009
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 Female 99 lb 7/16/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 99 lb 7/27/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 Female 106 lb 8/6/2009 Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 Female 106 lb 8/13/2009 Japan
Primary
Concomitant
Pyrexia Hospitalization 6/26/2009 Female 106 lb 8/20/2009 Japan
Primary
Concomitant
Stomatitis Hospitalization 7/15/2009 72 Female 114 lb 8/17/2009 Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/14/2009 Female 132 lb 8/26/2009 Japan
Primary
Secondary
Concomitant
Splenomegaly Other Serious 7/2/2009 Female 9/4/2009 Japan
Primary
Concomitant
Incorrect Dose Administered 9/24/2006 Female 148 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 4/1/2007 Female 145 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation 5/30/2008 Female 220 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Swelling 6/30/2008 Female 160 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting Death 3/2/2008 69 Female 9/8/2009 United States
Primary
Concomitant
Splenomegaly Life Threatening 7/2/2009 Female 9/21/2009 Japan
Primary
Concomitant
Tachycardia Other Serious 6/25/2009 Female 86 lb 9/22/2009 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 56 Male 9/15/2009 Physician China
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 56 Male 9/25/2009
Primary
Secondary
Stomatitis Hospitalization 7/15/2009 72 Female 114 lb 9/22/2009 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 6/15/2009 Female 129 lb 10/19/2009 Japan
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 10/14/2009 57 Female 10/23/2009 Physician Japan
Primary
Concomitant
Vomiting Death 3/2/2008 78 Female 10/17/2009 United States
Primary
Concomitant
Tendon Rupture Hospitalization 2/24/2009 Female 110 lb 11/2/2009 Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 9/15/2009 Female 128 lb 11/16/2009 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 6/25/2009 Female 86 lb 11/17/2009 Japan
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 1/1/2009 Female 140 lb 11/20/2009 Brazil
Primary
Concomitant
Tendon Rupture Hospitalization 11/5/2008 Female 103 lb 12/29/2009 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/29/2009 Female 128 lb 1/5/2010 Physician Japan
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 9/29/2009 Female 128 lb 1/13/2010 Physician Japan
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Nasopharyngitis Other Serious 1/1/2009 Female 140 lb 1/28/2010 Brazil
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 6/25/2009 Female 86 lb 2/3/2010 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/2/2009 Female 2/4/2010 Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/2/2009 Female 2/11/2010 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/1/2009 Female 2/11/2010 Japan
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant

Drug Data