Methotrexate combined with Seroquel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 1/13/2006 Physician United States
Primary
Concomitant
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 2/3/2006 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Thirst Other Serious 2/24/2006 Female 172 lb 3/8/2006 Consumer United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
Paraesthesia 4/12/2006 Female 12/20/2006 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 1/1/2006 61 Female 120 lb 1/2/2007 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 1/1/2007 49 Female 162 lb 2/13/2007 Consumer United States
Primary
Concomitant
Photophobia Other Serious Male 2/20/2007 Physician United Kingdom
Primary
Concomitant
Toothache Other Serious 1/1/2007 49 Female 162 lb 6/21/2007 Physician United States
Primary
Concomitant
Temperature Intolerance Other Serious 10/1/2006 Female 159 lb 8/20/2007 Other Health Professional Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 Male 211 lb 9/19/2007 Physician United States
Primary
Concomitant
Liver Function Test Abnormal 49 Female 9/19/2007 Physician United States
Primary
Concomitant
Tremor Hospitalization 5/8/2000 52 Female 291 lb 9/24/2007 Physician United States
Primary
Concomitant
Urticaria Other Serious 12/29/2006 Female 196 lb 10/5/2007 Other Health Professional Canada
Primary
Concomitant
Pneumonia Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Sensory Disturbance 8/21/2007 48 Female 161 lb 12/21/2007 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 4/25/2008 Female 113 lb 4/28/2008 Pharmacist United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 4/5/2003 Female 6/26/2008 Physician United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 4/9/2008 Male 174 lb 8/7/2008 Physician United States
Primary
Concomitant
Swelling Hospitalization 1/1/2008 Female 282 lb 9/8/2008 Physician France
Primary
Secondary
Concomitant
Death Death Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased 11/5/2008 Physician United Kingdom
Primary
Concomitant
Death Death 2/1/2009 52 Male 303 lb 4/3/2009 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/3/2009 United States
Primary
Secondary
Concomitant
Death Death 2/1/2009 52 Male 303 lb 4/10/2009 United States
Primary
Secondary
Plantar Fasciitis Other Serious 1/1/2009 Female 183 lb 4/10/2009 Physician United States
Primary
Concomitant
Death Death 2/1/2009 52 Male 303 lb 4/7/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/9/2000 50 Female 213 lb 4/14/2009 United States
Primary
Concomitant
Pain Death 2/1/2009 52 Male 303 lb 4/14/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/10/2009 Physician United States
Primary
Secondary
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/10/2009 Physician United States
Primary
Secondary
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2009 Female 191 lb 4/27/2009 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/29/2009 United States
Primary
Secondary
Insulin-requiring Type 2 Diabetes Mellitus Other Serious 4/29/2002 50 Female 388 lb 6/1/2009 United States
Primary
Concomitant
Gingival Ulceration Other Serious Female 158 lb 6/3/2009 Canada
Primary
Concomitant
Wrong Technique In Drug Usage Process 1/22/2009 Female 152 lb 6/11/2009 Physician United States
Primary
Concomitant
Pain 6/1/2006 Female 147 lb 6/11/2009 Physician United States
Primary
Concomitant
Tooth Fracture Other Serious Female 158 lb 6/19/2009 Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 53 Female 145 lb 7/14/2009 United States
Primary
Concomitant
Hidradenitis Other Serious 4/20/2009 Female 176 lb 7/17/2009 Netherlands
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 7/1/2009 Female 122 lb 7/17/2009 United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 7/1/2009 Female 122 lb 7/20/2009 United States
Primary
Concomitant
Weight Increased Other Serious 57 Female 135 lb 7/21/2009 United States
Primary
Concomitant
Hypoglycaemia Death 6/15/2006 19 Male 130 lb 7/22/2009 United States
Primary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/23/2003 56 Male 392 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Hidradenitis Other Serious 4/20/2009 Female 176 lb 7/30/2009 Netherlands
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/1/2009 Female 130 lb 8/13/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2003 38 Female 9/11/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 6/6/2009 Female 163 lb 9/18/2009 Other Health Professional United States
Primary
Concomitant
Injection Site Irritation 6/16/2009 Female 128 lb 9/19/2009 United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 2/2/2001 30 Female 273 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/22/2003 42 Female 246 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Sleep Disorder 7/18/2005 54 Female 236 lb 9/23/2009 United States
Primary
Concomitant
Hidradenitis Other Serious 4/20/2009 Female 176 lb 9/25/2009 Netherlands
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 72 Female 181 lb 10/5/2009 United States
Primary
Concomitant
Oesophageal Perforation Other Serious 4/1/2009 Female 185 lb 10/16/2009 United States
Primary
Concomitant
Urosepsis Life Threatening 9/21/2009 Male 150 lb 11/10/2009 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 2/9/2000 50 Female 213 lb 11/26/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2009 Female 130 lb 12/3/2009 United States
Primary
Secondary
Concomitant
Injection Site Pain 12/1/2008 Female 192 lb 12/9/2009 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness 1/29/2010 Pharmacist United States
Primary
Concomitant
Pain 10/1/2009 Female 130 lb 1/30/2010 United States
Primary
Concomitant
Staphylococcal Osteomyelitis Other Serious 1/1/2009 21 Female 141 lb 2/12/2010 Pharmacist United States
Primary
Concomitant
Hidradenitis Other Serious 4/20/2009 54 Female 176 lb 4/2/2010 Netherlands
Primary
Concomitant
Benign Ovarian Tumour Other Serious 3/1/2010 29 4/6/2010 United States
Primary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/15/2010 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/23/2007 62 Female 196 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/20/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/21/2010 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 80 Female 4/27/2010 Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 4/27/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/1/2009 80 Female 4/23/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/23/2010 57 Female 135 lb 4/29/2010 United States
Primary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 5/13/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 1/23/2010 70 Male 143 lb 7/1/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 6/6/2007 69 Female 174 lb 7/2/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 17 Male 130 lb 7/2/2010 United States
Primary
Concomitant
Liver Disorder Other Serious 6/27/2010 59 Female 154 lb 7/9/2010 Physician Canada
Primary
Concomitant
Liver Disorder Other Serious 6/27/2010 59 Female 154 lb 7/14/2010 Physician Canada
Primary
Concomitant
Liver Disorder Other Serious 6/27/2010 59 Female 154 lb 7/29/2010 Physician Canada
Primary
Concomitant
Somnolence Other Serious 9/8/2009 42 Female 250 lb 5/18/2010 United States
Primary
Concomitant
Amnesia Other Serious 33 Female 176 lb 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 38 Female 286 lb 8/5/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 50 Female 200 lb 8/27/2010 United States
Primary
Concomitant
Pancreatitis Relapsing Other Serious 1/1/1998 51 Male 179 lb 9/17/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 76 Female 150 lb 9/20/2010 Consumer United States
Primary
Concomitant
Urticaria 4/20/2010 Female 9/20/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 12/12/2009 76 Female 150 lb 9/20/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 10/30/2006 33 Male 175 lb 9/20/2010 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 5/13/2010 53 Female 9/20/2010 United States
Primary
Secondary
Concomitant
Hot Flush 62 Female 165 lb 9/20/2010 Consumer United States
Primary
Concomitant
Suicide Attempt Life Threatening 1/23/2010 70 Male 143 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 9/28/2010 75 Female 119 lb 10/14/2010 Consumer Brazil
Primary
Concomitant
Product Quality Issue 8/16/2010 59 Female 11/16/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 10/1/2010 61 Female 160 lb 11/6/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization Female 11/5/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/17/2010 12/21/2010 Pharmacist United States
Primary
Concomitant
Exostosis Hospitalization 9/15/2010 50 Male 175 lb 12/27/2010 Consumer United States
Primary
Concomitant
Hypertension 2/1/2010 57 Female 148 lb 1/28/2011 United States
Primary
Concomitant
Device Malfunction 7/1/2010 40 Female 1/29/2011 Consumer United States
Primary
Concomitant
Hordeolum 9/22/2010 51 Male 1/30/2011 Consumer United States
Primary
Concomitant
Sinusitis 10/1/2010 64 Female 1/30/2011 Consumer United States
Primary
Concomitant
Off Label Use Hospitalization 9/10/2010 65 Female 106 lb 1/31/2011 Physician United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 107 lb 2/2/2011 Physician United States
Primary
Secondary
Concomitant
Drug Screen Positive Hospitalization 9/10/2010 65 Female 106 lb 2/3/2011 Physician United States
Primary
Concomitant
Cholelithiasis Other Serious 6/27/2010 59 Female 154 lb 2/25/2011 Other Health Professional Canada
Primary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 107 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 11/11/2000 32 Female 123 lb 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 106 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Headache Other Serious 9/28/2010 75 Female 119 lb 3/16/2011 Consumer Brazil
Primary
Concomitant
Somnolence Other Serious 11/11/2000 32 Female 123 lb 3/17/2011 Consumer United States
Primary
Secondary
Concomitant
Meningitis Viral Hospitalization 3/7/2011 40 Female 202 lb 3/25/2011 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 11/1/2010 38 Female 3/30/2011 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 2/28/2011 59 Female 156 lb 4/5/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Meningitis Viral Hospitalization 3/7/2011 40 Female 202 lb 4/13/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2010 61 Female 160 lb 2/7/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 11/28/2010 62 Female 160 lb 2/7/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 10/1/2008 49 Female 163 lb 5/20/2011 Consumer United States
Primary
Secondary
Concomitant
Female Genital Operation Disability 11/11/2000 42 Female 123 lb 6/9/2011 Consumer United States
Primary
Secondary
Concomitant
Ear Infection 11/28/2010 62 Female 160 lb 5/12/2011 Consumer United States
Primary
Concomitant
Tendon Injury Hospitalization 11/11/2000 42 Female 123 lb 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Hospitalization 1/1/2010 47 Female 7/8/2011 Consumer Brazil
Primary
Concomitant
Antibody Test Positive Other Serious 1/1/2009 48 Female 178 lb 7/28/2011 Consumer United States
Primary
Concomitant
Hypercholesterolaemia Other Serious 3/1/2003 44 Female 8/2/2011 Consumer United States
Primary
Concomitant
Scoliosis Other Serious Female 8/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Death 40 Female 9/12/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Death 40 Female 9/13/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Impaired Work Ability Hospitalization 1/1/2010 48 Female 9/16/2011 Consumer United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 1/1/2010 48 Female 9/21/2011 Physician United States
Primary
Secondary
Concomitant
Intentional Drug Misuse 12/1/2009 59 Female 240 lb 9/22/2011 Consumer United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Death 7/2/2011 40 Female 157 lb 10/18/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 6/11/2011 40 Female 157 lb 10/21/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Parkinsonism Hospitalization 6/11/2011 41 Female 157 lb 10/25/2011 Physician Japan
Primary
Secondary
Concomitant
Kyphosis Other Serious Female 10/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Female 10/29/2011 Consumer United States
Primary
Concomitant
Pyloric Stenosis Other Serious 12/11/2009 57 Female 154 lb 10/28/2011 Lawyer United States
Primary
Concomitant
Dermatitis Psoriasiform Disability 1/1/2009 48 Female 178 lb 11/4/2011 Physician United States
Primary
Concomitant
Stress Urinary Incontinence Other Serious Female 11/7/2011 Physician United States
Primary
Secondary
Concomitant
Lymphadenitis Other Serious 1/1/2011 50 Female 11/17/2011 Physician United States
Primary
Concomitant
Cough Hospitalization 1/1/2011 52 Female 190 lb 11/18/2011 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious Female 11/21/2011 Lawyer United States
Primary
Secondary
Concomitant

Drug Data