Methotrexate combined with Zolpidem

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neutropenia Other Serious 9/27/2005 Female 163 lb 8/17/2006 Physician France
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/12/2005 50 Female 141 lb 5/23/2007 Physician United States
Primary
Concomitant
Leukoencephalopathy Other Serious 12/5/2006 70 Female 9/3/2007 Pharmacist Japan
Primary
Secondary
Subcutaneous Nodule Hospitalization 10/25/2005 Male 2/15/2008 France
Primary
Concomitant
Pancreatitis Acute Hospitalization 21 Male 2/21/2008 France
Primary
Secondary
Concomitant
Influenza Hospitalization 2/18/2008 Female 194 lb 2/28/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 12/9/2007 Female 135 lb 3/15/2008 United States
Primary
Concomitant
Gastric Ulcer Hospitalization 12/20/2007 65 Female 99 lb 4/4/2008 Other Health Professional Korea, Republic Of
Primary
Concomitant
Thrombocytopenia Death 6/9/2008 Male 120 lb 6/24/2008 Physician Korea, Republic Of
Primary
Concomitant
Gastric Ulcer Hospitalization 12/20/2007 65 Female 99 lb 7/2/2008 Other Health Professional Korea, Republic Of
Primary
Concomitant
Ovarian Epithelial Cancer Other Serious 10/1/2007 61 Female 7/21/2008 Physician Belgium
Primary
Concomitant
Pneumonia Hospitalization 6/9/2008 Male 120 lb 7/16/2008 Physician Korea, Republic Of
Primary
Concomitant
Ovarian Epithelial Cancer Other Serious 10/1/2007 61 Female 8/8/2008 Physician Belgium
Primary
Concomitant
Retinal Vein Thrombosis Hospitalization 8/8/2008 Female 172 lb 8/29/2008 Physician Germany
Primary
Secondary
Concomitant
Injection Site Haemorrhage 6/26/2008 Female 185 lb 9/12/2008 Consumer United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2008 Male 200 lb 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Retinal Vein Thrombosis Hospitalization 8/8/2008 Female 172 lb 11/7/2008 Physician Germany
Primary
Secondary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Foot Operation Hospitalization 11/6/2008 Female 11/25/2008 Belgium
Primary
Concomitant
Tuberculosis Hospitalization 5/1/2008 33 Female 11/26/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Toe Operation Hospitalization 11/6/2008 Female 12/2/2008 Belgium
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 7/1/2008 Male 12/3/2008 Physician France
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 46 Female 12/4/2008
Primary
Secondary
Concomitant
Venous Thrombosis Limb Hospitalization 1/1/2008 Male 12/4/2008 Physician France
Primary
Concomitant
Meniscus Lesion Hospitalization 4/1/2008 Female 12/10/2008 Belgium
Primary
Concomitant
Foot Deformity Other Serious Female 12/12/2008 Belgium
Primary
Concomitant
Sepsis Hospitalization 11/14/2008 12/17/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Pain Hospitalization 8/4/2008 Female 154 lb 1/21/2009 United Kingdom
Primary
Concomitant
Breast Cancer In Situ Other Serious 7/10/2007 Female 159 lb 5/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tenosynovitis Hospitalization 4/1/2007 Female 100 lb 5/26/2009 Physician United Kingdom
Primary
Concomitant
Skin Cancer Other Serious 2/6/2007 157 lb 5/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 12/12/2008 Female 282 lb 7/10/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/5/2009 68 Female 7/13/2009 Other Health Professional Argentina
Primary
Secondary
Concomitant
Viral Infection Hospitalization 6/5/2009 68 Female 7/15/2009 Other Health Professional Argentina
Primary
Secondary
Concomitant
Necrosis Other Serious 7/10/2007 Female 159 lb 7/17/2009 United Kingdom
Primary
Concomitant
Breast Cancer In Situ Other Serious 5/31/2007 Female 159 lb 7/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2009 Female 131 lb 8/5/2009 Physician Argentina
Primary
Secondary
Concomitant
Incorrect Dose Administered 7/8/2007 Female 182 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 6/26/2008 Female 185 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting Death 3/2/2008 69 Female 9/8/2009 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 46 Female 9/9/2009 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2009 Female 144 lb 10/6/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2009 Female 131 lb 10/6/2009 Physician Argentina
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2009 Female 131 lb 10/14/2009 Physician Argentina
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2009 Female 131 lb 10/21/2009 Physician Argentina
Primary
Secondary
Concomitant
Vomiting Death 3/2/2008 78 Female 10/17/2009 United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 2/6/2007 Female 157 lb 12/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased 5/1/2009 Female 12/9/2009 Physician United States
Primary
Concomitant
Sinus Congestion 6/15/2009 12/9/2009 Physician United States
Primary
Concomitant
Oropharyngeal Blistering 7/27/2009 66 Female 143 lb 12/21/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 9/16/2009 Male 170 lb 1/29/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 59 Female 170 lb 2/22/2010 Consumer United States
Primary
Concomitant
Gynaecomastia Hospitalization 8/1/2009 Male 3/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Gynaecomastia Hospitalization 1/1/2009 45 Male 3/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 1/24/2009 44 Female 198 lb 4/8/2010 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2009 49 Female 150 lb 4/9/2010 United States
Primary
Concomitant
Vomiting Life Threatening 1/24/2009 44 Female 198 lb 4/14/2010 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 2/10/2010 34 Male 130 lb 4/19/2010 Physician France
Primary
Concomitant
Vomiting Other Serious 2/10/2010 34 Male 130 lb 4/21/2010 Physician France
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 49 Female 150 lb 4/26/2010
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 49 Female 150 lb 5/17/2010
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/8/2010 53 Female 131 lb 5/20/2010 Physician Czech Republic
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 2/8/2010 53 Female 131 lb 6/17/2010 Physician Czech Republic
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 10/1/2001 41 Female 157 lb 6/28/2010 Physician France
Primary
Secondary
Concomitant
Nausea 10/15/2008 66 Female 200 lb 7/23/2010 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 9/21/2009 37 Female 93 lb 8/9/2010 Physician Japan
Primary
Concomitant
Pustular Psoriasis Hospitalization Female 269 lb 8/12/2010 Physician France
Primary
Concomitant
Renal Colic Hospitalization 7/23/2010 32 Female 8/19/2010 Other Health Professional Argentina
Primary
Secondary
Concomitant
Renal Colic Hospitalization 7/23/2010 32 Female 8/23/2010 Other Health Professional Argentina
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 2/8/2010 53 Female 131 lb 8/25/2010 Physician Czech Republic
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 8/10/2010 57 Female 8/20/2010 Other Health Professional Japan
Primary
Concomitant
Pruritus 3/29/2010 70 Female 200 lb 8/28/2010 United States
Primary
Concomitant
Weight Increased Other Serious 9/23/2010 43 Female 161 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 8/23/2010 11/22/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/22/2010 Physician South Africa
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/24/2010 Physician South Africa
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/24/2010 Physician South Africa
Primary
Concomitant
Injection Site Swelling 2/15/2010 12/19/2010 Consumer United States
Primary
Concomitant
Pelvic Fracture Other Serious Female 12/17/2010 Consumer United States
Primary
Concomitant
Injection Site Haematoma 7/13/2010 12/22/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 12/23/2010 Physician South Africa
Primary
Concomitant
Herpes Simplex 8/19/2006 12/23/2010 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 8/23/2010 12/28/2010 United States
Primary
Concomitant
Erythema Other Serious 7/1/2010 52 Female 137 lb 1/6/2011 Consumer United States
Primary
Concomitant
Hydronephrosis Other Serious 5/30/1996 48 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 11/4/2010 63 Male 158 lb 1/18/2011 Physician South Africa
Primary
Concomitant
Transient Ischaemic Attack Other Serious Female 1/17/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 8/31/2010 36 Female 1/29/2011 Consumer United States
Primary
Concomitant
Blister 7/11/2010 64 Female 1/29/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 5/1/2010 55 Female 160 lb 1/29/2011 Consumer United States
Primary
Concomitant
Constipation 7/1/2010 64 Female 1/30/2011 Consumer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 9/1/2010 58 Female 1/30/2011 Consumer United States
Primary
Concomitant
Dyspepsia 1/1/2009 58 Female 245 lb 1/30/2011 Physician United States
Primary
Concomitant
Delirium Hospitalization Female 2/3/2011 Physician United States
Primary
Concomitant
Renal Atrophy Other Serious 5/30/1996 48 Female 2/10/2011 United States
Primary
Secondary
Concomitant
Anxiety Other Serious 5/30/1996 48 Female 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Death Other Serious 1/22/2011 76 Female 2/28/2011 Physician United States
Primary
Concomitant
Opportunistic Infection Other Serious 10/17/2010 28 Female 249 lb 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Mesangioproliferative Glomerulonephritis Hospitalization 1/1/2009 48 Female 254 lb 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 12/15/2010 68 Female 175 lb 3/21/2011 Consumer United States
Primary
Concomitant
Oedema Mouth Hospitalization 7/1/2010 52 Female 137 lb 3/25/2011 Consumer United States
Primary
Concomitant
Lower Respiratory Tract Infection Fungal Death 1/9/2011 28 Female 249 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Eczema 1/1/2011 64 Female 207 lb 2/7/2011 Consumer United States
Primary
Concomitant
Toothache Hospitalization 9/21/2009 37 Female 93 lb 4/14/2011 Physician Japan
Primary
Concomitant
Anxiety Death Female 116 lb 4/20/2011 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 12/27/2010 49 Female 4/28/2011 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/24/2010 43 Female 205 lb 5/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization Female 116 lb 5/10/2011 Consumer United States
Primary
Concomitant
Tuberculosis Gastrointestinal Hospitalization 1/25/2010 65 Female 93 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Discomfort Other Serious 170 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cognitive Disorder Hospitalization Female 116 lb 5/23/2011 Consumer United States
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 4/20/2011 52 Female 6/3/2011 Physician Belgium
Primary
Concomitant
Dyspnoea Hospitalization 5/3/2011 82 Female 6/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 52 Female 146 lb 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 52 Female 146 lb 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 7/9/2008 50 Female 6/13/2011 Lawyer United States
Primary
Concomitant
Nausea Hospitalization 12/28/2010 38 Female 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Death 7/9/2008 50 Female 6/20/2011 Physician United States
Primary
Concomitant
Anal Fissure Hospitalization 6/9/2011 24 Female 132 lb 6/14/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/24/2011 82 Female 6/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Choking Sensation Other Serious 5/1/2011 70 Female 135 lb 6/23/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/20/2011 52 Female 181 lb 6/24/2011 Physician Belgium
Primary
Concomitant
Osteoarthritis Other Serious 5/19/2011 77 Female 132 lb 6/29/2011 Physician Japan
Primary
Concomitant
Arterial Thrombosis Hospitalization 4/20/2011 52 Female 181 lb 7/7/2011 Physician Belgium
Primary
Concomitant
Melaena Other Serious 10/18/2009 48 Female 97 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 12/28/2010 38 Female 7/14/2011 Physician Japan
Primary
Secondary
Concomitant
Photosensitivity Reaction Hospitalization 4/1/2010 64 Female 112 lb 7/14/2011 Consumer United States
Primary
Concomitant
Aortic Dissection Hospitalization 7/29/2007 73 Female 110 lb 7/15/2011 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 12/28/2010 38 Female 7/20/2011 Physician Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Iv Other Serious 8/31/2009 73 Female 157 lb 7/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Choking Sensation Other Serious 5/1/2011 70 Female 135 lb 7/26/2011 Consumer United States
Primary
Concomitant
Coronary Artery Embolism Hospitalization 4/20/2011 52 Female 181 lb 7/29/2011 Physician Belgium
Primary
Concomitant
Lung Neoplasm Malignant Death 4/20/2011 52 Female 7/29/2011 Physician Belgium
Primary
Concomitant
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 2/16/2010 27 Female 8/9/2011 Other Health Professional Italy
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/20/2011 52 Female 181 lb 8/12/2011 Physician Belgium
Primary
Concomitant
Dry Skin Other Serious 52 Female 146 lb 8/24/2011 Consumer United States
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 6/16/2011 23 Male 307 lb 8/18/2011 Physician United States
Primary
Secondary
Concomitant
Dental Alveolar Anomaly Hospitalization Female 8/26/2011 Physician France
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 7/19/2011 80 Male 8/26/2011 Physician France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/1/2009 61 Female 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Arthralgia Hospitalization 6/21/2011 73 Female 82 lb 8/30/2011 Physician Japan
Primary
Concomitant
Pancreatitis Chronic Other Serious 7/9/2010 54 Male 117 lb 9/1/2011 Physician Japan
Primary
Concomitant
Accidental Overdose Death 48 Female 247 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Epilepsy Hospitalization 7/19/2011 79 Male 8/24/2011 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/19/2011 79 Male 8/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Drug Abuse Death 48 Female 247 lb 9/14/2011 Physician United States
Primary
Secondary
Concomitant
Renal Pain Other Serious 1/1/2001 50 Female 230 lb 9/19/2011 Consumer United States
Primary
Concomitant
Metastases To Peritoneum Other Serious 11/1/2009 61 Female 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Psoriasis Hospitalization 9/3/2008 58 Female 9/30/2011 Other Health Professional France
Primary
Concomitant

Drug Data