Methotrexate combined with Synthroid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Artery Stent Placement Hospitalization 4/1/2005 Female 1/3/2006 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/2005 Female 154 lb 1/3/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/1/2000 75 Male 181 lb 1/4/2006 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 11/17/2005 Female 175 lb 1/5/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 11/1/2002 Female 1/6/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/1998 58 Female 196 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Ankle Fracture Other Serious 8/1/2005 Female 281 lb 1/24/2006 Physician United States
Primary
Concomitant
Rash Pruritic Hospitalization 8/13/2005 Female 123 lb 1/26/2006 Physician United States
Primary
Concomitant
Gastrointestinal Disorder Hospitalization 2/1/2005 Female 170 lb 1/27/2006 Physician United States
Primary
Concomitant
Rash 3/29/2005 50 Female 239 lb 2/15/2006 Consumer United States
Primary
Concomitant
Pulmonary Cavitation Other Serious 6/5/2003 Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Insomnia 6/1/2005 56 Female 155 lb 1/5/2006 Consumer United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Death Female 3/1/2006 Physician United States
Primary
Concomitant
Renal Failure Life Threatening 1/1/2006 Female 170 lb 3/14/2006 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2005 Female 3/20/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/1/2004 Male 182 lb 3/20/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2002 61 Female 198 lb 3/20/2006 Consumer United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
Tuberculosis Other Serious Female 196 lb 3/27/2006 Other Health Professional United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2003 63 Female 3/23/2006 United States
Primary
Concomitant
Headache 1/1/2005 75 Female 194 lb 1/20/2006 Consumer United States
Primary
Concomitant
Pain Hospitalization 2/27/2006 Female 150 lb 4/4/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2002 Female 131 lb 4/7/2006 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 11/1/2005 Female 4/17/2006 Physician United States
Primary
Concomitant
Varices Oesophageal Hospitalization 12/15/2005 76 Female 170 lb 4/13/2006 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/6/2006 Female 4/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 12/7/2005 Female 204 lb 4/24/2006 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 6/3/2002 70 Male 130 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 8/20/2001 63 Female 198 lb 4/26/2006 Lawyer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/27/2006 Female 150 lb 4/26/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2005 Female 4/27/2006 Other Health Professional United States
Primary
Concomitant
Urinary Retention 57 Female 4/28/2006 Consumer United States
Primary
Secondary
Concomitant
Adenocarcinoma Other Serious 5/5/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/16/2002 66 Female 201 lb 5/10/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2005 60 Female 5/11/2006 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 7/1/2005 Male 5/11/2006 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9/1/2005 Female 5/12/2006 Physician United States
Primary
Concomitant
Cardiomyopathy Hospitalization 11/9/2005 Female 210 lb 5/15/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 53 Female 95 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Tremor Hospitalization 1/1/2005 85 Female 5/10/2006 Consumer United States
Primary
Concomitant
Septic Shock Life Threatening 3/1/2005 Female 180 lb 5/30/2006 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2006 Female 5/31/2006 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2005 Female 254 lb 6/6/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Death Female 6/12/2006 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 5/19/2006 Female 6/21/2006 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 4/1/2006 56 Female 193 lb 6/20/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 Female 6/28/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/25/2005 Female 115 lb 7/7/2006 Physician United States
Primary
Concomitant
Cerebellar Tumour Hospitalization 12/19/2005 Female 7/10/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2005 Female 7/17/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 32 Female 7/3/2006 Consumer United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 4/1/2006 56 Female 193 lb 7/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 132 lb 7/31/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 8/1/2002 Male 180 lb 8/7/2006 Physician United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 4/1/2006 56 Female 193 lb 8/8/2006 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 1/1/2006 Female 240 lb 8/15/2006 Physician United States
Primary
Concomitant
Hypoaesthesia Facial Other Serious 12/27/2004 66 Male 8/11/2006 Pharmacist United States
Primary
Concomitant
Sjogren's Syndrome Other Serious 8/1/2000 Female 132 lb 8/17/2006 Consumer United States
Primary
Concomitant
Skin Disorder Other Serious 1/1/2002 Female 190 lb 8/28/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 6/20/2006 67 Female 152 lb 7/21/2006 Consumer United States
Primary
Concomitant
Thyroid Disorder Other Serious 6/19/2006 65 Female 170 lb 9/5/2006 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 3/20/2006 71 Female 9/6/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 1/1/2004 Female 9/8/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 3/1/2006 Female 225 lb 9/15/2006 Consumer United States
Primary
Concomitant
Hepatic Cyst Other Serious 1/1/2004 Female 176 lb 9/22/2006 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/17/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 8/1/2002 Male 180 lb 9/27/2006 Physician United States
Primary
Concomitant
Herpes Zoster 5/18/2006 71 Female 196 lb 10/2/2006 Consumer United States
Primary
Concomitant
Urticaria 6/20/2006 47 Female 139 lb 10/2/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 8/7/2006 48 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Other Serious 9/7/2004 Female 159 lb 10/4/2006 Consumer United States
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2005 Female 10/5/2006 Physician United States
Primary
Concomitant
Histoplasmosis Disseminated Death Female 10/10/2006 Physician United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 7/22/2006 Male 198 lb 10/11/2006 Physician United States
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 4/1/2006 Female 10/13/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 9/11/2006 Female 10/13/2006 Physician United States
Primary
Secondary
Concomitant
Autoimmune Thyroiditis Hospitalization 10/11/2006 51 Female 10/18/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Histoplasmosis Disseminated Hospitalization Female 10/19/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/24/2006 70 Female 112 lb 10/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hepatic Mass Other Serious Female 182 lb 11/1/2006 Physician United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 4/1/2006 Female 11/3/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 9/11/2006 Female 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Thyroiditis Fibrous Chronic Hospitalization 10/11/2006 51 Female 11/6/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thyroiditis Fibrous Chronic Hospitalization 10/11/2006 51 Female 11/9/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Urosepsis Hospitalization 8/26/2006 Female 11/10/2006 Physician United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 11/1/2006 Female 182 lb 11/20/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/14/2006 69 Female 119 lb 12/6/2006 Physician Canada
Primary
Concomitant
Nausea Other Serious 11/21/2006 74 Female 143 lb 12/6/2006 Consumer United States
Primary
Concomitant
Bronchitis Hospitalization 6/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Histoplasmosis Disseminated Other Serious 7/7/2006 Female 206 lb 12/11/2006 Physician Canada
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 7/1/2000 Female 132 lb 12/13/2006 Physician United States
Primary
Concomitant
Thyroiditis Fibrous Chronic Hospitalization 10/11/2006 51 Female 12/13/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Arthralgia 4/21/2006 Female 12/13/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 9/21/2006 41 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Humerus Fracture 7/5/2006 Female 12/15/2006 Other Health Professional United States
Primary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 12/18/2006 Physician United States
Primary
Concomitant
Nasopharyngitis 9/5/2006 Female 12/19/2006 Physician United States
Primary
Concomitant
Urosepsis Hospitalization 8/26/2006 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 56 Female 12/13/2006 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage 11/5/2005 Female 12/21/2006 Consumer United States
Primary
Concomitant
Paraesthesia Oral 7/6/2006 54 Female 12/22/2006 Physician United States
Primary
Concomitant
Pruritus 5/25/2006 51 Female 168 lb 12/22/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 73 Female 12/28/2006 Consumer United States
Primary
Concomitant
Viral Myocarditis Death 9/21/2006 41 Female 12/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 7/2/2002 Female 120 lb 1/5/2007 Lawyer United States
Primary
Concomitant
Injury Other Serious 7/2/2002 Female 120 lb 1/17/2007 Lawyer United States
Primary
Concomitant
Death Death 12/1/2006 81 Female 1/8/2007 Consumer Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 11/14/2006 69 Female 119 lb 1/25/2007 Physician Canada
Primary
Concomitant
Atrial Fibrillation Hospitalization 5/1/2006 Male 145 lb 1/29/2007 Physician United States
Primary
Concomitant
Nausea Life Threatening 1/11/2007 83 Female 180 lb 2/6/2007 Physician United States
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 4/26/2006 Female 2/28/2007 Other Health Professional Canada
Primary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 10/11/2006 51 Female 3/19/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/21/2006 41 Female 123 lb 3/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 5/6/2003 57 Female 152 lb 11/27/2006 United States
Primary
Concomitant
Acute Myocardial Infarction Other Serious 11/9/2001 48 Female 11/27/2006 United States
Primary
Concomitant
Hypersensitivity Life Threatening 12/13/2006 68 Female 3/27/2007 Consumer United States
Primary
Concomitant
Respiratory Disorder Hospitalization 10/9/2006 Female 3/28/2007 Physician United States
Primary
Concomitant
Haemorrhage Hospitalization 5/30/2006 55 Female 116 lb 12/4/2006 United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 6/4/2006 Female 170 lb 4/4/2007 Consumer United States
Primary
Secondary
Concomitant
Toxic Shock Syndrome Hospitalization 56 Female 3/30/2007 Consumer United States
Primary
Concomitant
Scotoma Other Serious 7/1/2005 Male 236 lb 3/19/2007 Physician United States
Primary
Concomitant
Lupus-like Syndrome Other Serious 10/1/2006 51 Female 185 lb 4/27/2007 Consumer United States
Primary
Concomitant
Uterine Perforation Other Serious 6/20/2006 34 Female 159 lb 1/25/2007 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/8/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/10/2007 Physician United States
Primary
Concomitant
Somnolence Other Serious 5/1/2007 53 Female 210 lb 5/24/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/25/2007 Physician United States
Primary
Concomitant
Histoplasmosis Disseminated Other Serious 7/7/2006 Female 206 lb 6/22/2007 Physician Canada
Primary
Concomitant
Retinal Detachment Other Serious 4/2/2007 Male 6/22/2007 Physician Canada
Primary
Concomitant
Swelling Other Serious 12/1/2006 Female 150 lb 6/26/2007 Physician United States
Primary
Concomitant
Necrotising Fasciitis Hospitalization 4/28/2007 Female 117 lb 6/27/2007 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 6/29/2007 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 7/3/2007 Physician United States
Primary
Concomitant
Death Death Female 97 lb 7/19/2007 Other Health Professional Canada
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 7/24/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased 1/1/2004 Female 149 lb 7/26/2007 Consumer United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 8/2/2007 Physician United States
Primary
Concomitant
Femur Fracture Other Serious 6/26/2007 63 Female 200 lb 8/5/2007 Consumer United States
Primary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 8/7/2007 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/1998 Female 8/16/2007 Consumer United States
Primary
Concomitant
Therapy Regimen Changed 8/17/2007 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/28/2006 Female 171 lb 9/10/2007 Physician United States
Primary
Concomitant
Tremor Hospitalization 5/8/2000 52 Female 291 lb 9/24/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2006 55 Female 175 lb 9/14/2007 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 9/27/2007 Physician United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 7/28/2006 Male 198 lb 8/22/2007 Other Health Professional United States
Primary
Concomitant

Drug Data