Bleomycin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancytopenia Other Serious 11/15/2004 36 Male 1/10/2006 Consumer United States
Primary
Secondary
Concomitant
Deafness Hospitalization 12/2/2005 57 Female 1/17/2006 France
Primary
Secondary
Myelodysplastic Syndrome Other Serious 11/15/2004 36 Male 1/24/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious 11/15/2004 36 Male 1/24/2006 Consumer United States
Primary
Secondary
Concomitant
Psychomotor Skills Impaired Other Serious 64 Male 2/2/2006
Primary
Secondary
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
Pneumonia Death 2/13/2004 63 Male 4/14/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/7/2006 40 Female 209 lb 4/14/2006 Physician France
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 66 Male 4/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 66 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Eosinophilic Leukaemia Hospitalization 12/1/2000 43 Male 5/5/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious 11/15/2004 36 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 2/24/2006 31 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 66 Male 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Death 66 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Chronic Eosinophilic Leukaemia Hospitalization 12/1/2000 43 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Hospitalization 1/1/2001 43 Male 5/16/2006
Primary
Secondary
Thrombocytopenia Death 5/30/2006 59 Male 143 lb 6/12/2006 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 6/16/2006 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 6/26/2006 Physician France
Primary
Secondary
Peritonitis Hospitalization 1/1/2001 56 Male 7/25/2006 Consumer United States
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 65 Male 7/28/2006 Physician Italy
Primary
Concomitant
Sepsis Death 39 Male 10/17/2006 Physician United States
Primary
Concomitant
Liver Disorder Hospitalization 10/1/2005 66 Male 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/2/2006 56 Female 115 lb 10/26/2006 Physician France
Primary
Secondary
Pulmonary Fibrosis Death 4/9/1986 70 Male 12/6/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/28/2006 61 Male 176 lb 12/21/2006 Physician France
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 11/27/2006 41 Male 152 lb 12/28/2006 Physician France
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 12/23/2006 56 Female 1/8/2007 Physician France
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 11/9/2006 57 Female 110 lb 1/12/2007 Physician France
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 1/10/2007 Physician Finland
Primary
Secondary
Concomitant
Purpura Hospitalization 12/23/2006 56 Female 104 lb 1/24/2007 Physician France
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Hospitalization 66 Female 2/26/2007
Primary
Secondary
Concomitant
Ureteric Obstruction Hospitalization 66 Female 2/22/2007 Physician Italy
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 66 2/19/2007 Italy
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 66 Female 3/1/2007 Italy
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 66 Female 3/2/2007 Other Health Professional Italy
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 66 Female 3/5/2007 Consumer Japan
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 11/27/2006 41 Male 152 lb 3/2/2007 Physician France
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 66 Female 3/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Hospitalization 66 Female 3/8/2007 Italy
Primary
Secondary
Pneumonitis Hospitalization 2/11/2007 65 Male 157 lb 3/2/2007 Physician France
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Hospitalization 66 Female 3/13/2007 Consumer United States
Primary
Secondary
Vomiting Hospitalization 3/1/2007 52 Male 3/12/2007 Physician France
Primary
Secondary
Pulmonary Mass Hospitalization 2/11/2007 65 Male 157 lb 3/23/2007 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/1/2007 52 Male 159 lb 3/23/2007 Physician France
Primary
Secondary
Ulcer Hospitalization 3/4/2007 28 Female 110 lb 3/23/2007 Physician France
Primary
Secondary
Somnolence Other Serious 6/6/2005 40 Male 4/18/2007 Other Health Professional Malaysia
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 1/1/2006 66 Female 4/11/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Tongue Coated Hospitalization 2/1/2007 65 Male 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 3/22/2007 58 Male 139 lb 4/27/2007 Physician France
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious 7/1/2005 66 Male 5/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 3/22/2007 58 Male 139 lb 5/10/2007 Physician France
Primary
Secondary
Concomitant
Tongue Coated Hospitalization 2/1/2007 65 Male 5/17/2007 Consumer Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 5/11/2007 Physician France
Primary
Secondary
Oesophageal Ulcer Hospitalization 12/21/2006 56 Female 104 lb 5/11/2007 Physician France
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Hospitalization 2/11/2007 65 Male 157 lb 5/14/2007 Physician France
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 2/11/2007 65 Male 157 lb 5/17/2007 Physician France
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 6/1/2007 Physician Germany
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 6/1/2007 Physician Germany
Primary
Secondary
Tongue Disorder Hospitalization 2/11/2007 65 Male 157 lb 6/18/2007 Physician France
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 7/9/2007 United Kingdom
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 1/1/2002 67 Female 7/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Aplasia Hospitalization 6/22/2007 43 Male 152 lb 7/16/2007 Physician France
Primary
Secondary
Metastasis Hospitalization 1/1/2002 67 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraparesis Life Threatening 1/1/2002 67 Female 7/20/2007 United Kingdom
Primary
Secondary
Metastasis Hospitalization 1/1/2002 40 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraparesis Hospitalization 1/1/2002 40 Male 8/3/2007 Argentina
Primary
Secondary
Metastasis Hospitalization 1/1/2002 40 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 1/1/2002 40 Female 8/8/2007 Consumer United States
Primary
Secondary
Pleocytosis Life Threatening 1/1/2002 40 Female 8/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 17 Male 8/9/2007 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious 70 Female 8/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastasis Other Serious 40 Male 8/10/2007 Physician Argentina
Primary
Secondary
Concomitant
Spinal Anaesthesia Hospitalization 67 Female 8/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Spinal Anaesthesia Life Threatening 1/1/2002 40 Male 8/10/2007 United Kingdom
Primary
Secondary
Neutropenia Other Serious 70 Female 8/20/2007 United Kingdom
Primary
Secondary
Concomitant
Spinal Anaesthesia Life Threatening 1/1/2002 40 Male 8/15/2007 United Kingdom
Primary
Secondary
Tongue Haemorrhage Hospitalization 2/11/2007 65 Male 157 lb 8/21/2007 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 8/22/2007 Physician France
Primary
Secondary
Pancytopenia Hospitalization 12/21/2006 56 Female 104 lb 8/22/2007 Physician France
Primary
Secondary
Concomitant
Spinal Anaesthesia Hospitalization 1/1/2002 40 Female 8/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastasis Hospitalization 1/1/2002 40 Female 9/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 12/23/2006 56 Female 104 lb 9/20/2007 Physician France
Primary
Secondary
Concomitant
Pulmonary Embolism Death Male 9/26/2007 Other Health Professional Japan
Primary
Secondary
Pneumonia Bacterial Death Male 9/26/2007 Other Health Professional Japan
Primary
Secondary
Embolism Death Male 9/27/2007 Other Health Professional Japan
Primary
Secondary
Neutropenia Other Serious 67 Male 9/27/2007 United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/25/2007 29 Male 181 lb 10/22/2007 Physician France
Primary
Secondary
Sepsis Other Serious 70 Female 11/13/2007 Consumer United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 4/1/2007 61 Male 11/16/2007 Consumer United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/22/2007 57 Male 11/16/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 70 Female 11/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Haematotoxicity Other Serious 11/27/2007 Other Health Professional Germany
Primary
Secondary
Haematotoxicity Other Serious 11/27/2007 Other Health Professional Germany
Primary
Secondary
Haematotoxicity Other Serious 11/27/2007 Other Health Professional Germany
Primary
Secondary
Bone Marrow Failure Hospitalization 5/27/2007 Male 12/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Pneumonitis Hospitalization 2/11/2007 65 Male 157 lb 12/6/2007 Physician France
Primary
Secondary
Concomitant
Treatment Failure Hospitalization 5/19/2006 59 Male 65 lb 12/5/2007 Physician France
Primary
Secondary
Testis Cancer Other Serious 30 Male 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 12/23/2006 56 Female 104 lb 12/12/2007 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/17/2007 56 Female 104 lb 12/14/2007 Physician France
Primary
Secondary
Stomatitis Other Serious 12/21/2007 Other Health Professional Japan
Primary
Secondary
Renal Failure Acute Other Serious 12/21/2007 Other Health Professional Japan
Primary
Secondary
Large Intestinal Haemorrhage Hospitalization 45 Male 12/28/2007 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious Male 12/31/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 33 Female 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 33 Female 2/5/2008 Consumer United States
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Hospitalization Male 150 lb 2/8/2008 Consumer United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/25/2007 29 Male 181 lb 2/21/2008 Physician France
Primary
Secondary
Large Intestinal Haemorrhage Hospitalization Male 150 lb 2/29/2008 Consumer United Kingdom
Primary
Concomitant
Exsanguination Life Threatening 10/23/1986 23 Male 154 lb 3/31/2008 Physician United Kingdom
Primary
Concomitant
Pneumonia Death 60 Male 9/9/2008 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 1/16/2009 Female 2/24/2009 Physician United Kingdom
Primary
Secondary
Lymphadenitis Other Serious 3 Male 2/25/2009
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/12/2008 Male 2/27/2009 Physician United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/1/2008 3/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/1/2008 3/17/2009 Other Health Professional France
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 55 Male 3/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 55 Male 4/7/2009 Austria
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Fat Embolism Hospitalization 22 Male 3/26/2010 Greece
Primary
Secondary
Acute Myeloid Leukaemia Death 39 Male 4/16/2010 Other Health Professional United States
Primary
Secondary
Respiratory Failure Hospitalization 11/1/2007 36 Male 7/16/2010 Consumer France
Primary
Secondary
Tachycardia Other Serious 25 Female 102 lb 7/27/2010 Physician United States
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 5/29/2010 22 Male 9/20/2010 Other Health Professional France
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 2/4/2011 64 Male 4/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Death 4/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Human Chorionic Gonadotropin Increased Hospitalization 36 Female 3/30/2011 Physician United Kingdom
Primary
Concomitant
Agranulocytosis Hospitalization 2/4/2011 64 Male 4/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 73 8/30/2011 Physician Japan
Primary
Secondary
Oral Herpes Required Intervention 61 Female 8/24/2012 Us
Primary
Secondary
Renal Tubular Necrosis Death 61 Female 9/20/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 60 Male 1/4/2013 Physician Fr
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 53 Female 1/4/2013 Physician Fr
Primary
Secondary
Stomatitis Hospitalization 19 Male 117 lb 10/7/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 61 Male 1/4/2013 Physician Fr
Primary
Secondary
Concomitant
Stomatitis Other Serious 19 Male 10/11/2012 Jp
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 53 Female 10/22/2012 Country Not Specified
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 64 Female 11/12/2012 Physician It
Primary
Secondary
Febrile Neutropenia Death 11/20/2012 Other Health Professional Fr
Primary
Secondary
Intestinal Obstruction Death 11/20/2012 Other Health Professional Fr
Primary
Secondary
Liver Injury Other Serious 11/20/2012 Physician Country Not Specified
Primary
Secondary
White Blood Cell Count Decreased Other Serious 64 Female 11/20/2012 Physician It
Primary
Secondary
Immunosuppression Other Serious 64 Female 12/13/2012 Physician It
Primary
Secondary
Ototoxicity Other Serious NotSpecified 1/3/2013 Other Health Professional Nl
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 53 Female 1/2/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Off Label Use Death Female 12/19/2012 Other Health Professional Cn
Primary
Secondary
Toxic Encephalopathy Other Serious NotSpecified 1/3/2013 Other Health Professional Nl
Primary
Secondary

Drug Data