Enbrel combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Level Increased 7/29/2005 1/3/2006 Physician United States
Primary
Concomitant
Cardiac Failure Other Serious 47 Male 243 lb 1/3/2006 Physician Switzerland
Primary
Concomitant
Weight Decreased Life Threatening 6/1/2003 Female 144 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 12/11/2005 64 Male 1/4/2006 Consumer France
Primary
Secondary
Syncope Vasovagal Hospitalization 6/11/2005 Male 150 lb 1/4/2006 Physician France
Primary
Secondary
Recurrent Cancer Other Serious 62 Male 1/4/2006 Consumer United Kingdom
Primary
Concomitant
Jaundice Hospitalization 11/7/2005 Female 1/4/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Level Increased 7/29/2005 1/4/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 8/28/2003 73 Female 258 lb 1/4/2006 Physician United States
Primary
Concomitant
Breast Cancer Stage Iii Hospitalization 9/19/2005 Female 1/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Nephrotic Syndrome Hospitalization 10/24/2005 Male 1/5/2006 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 11/28/2005 Female 1/5/2006 Physician United States
Primary
Secondary
Concomitant
Personality Change Other Serious 1/1/2004 Female 1/5/2006 Other Health Professional France
Primary
Concomitant
Neutropenia Other Serious 11/15/2005 Female 1/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 11/1/2002 Female 1/6/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 1/6/2006 Physician Belgium
Primary
Secondary
Urticaria Hospitalization 8/23/2005 49 Female 120 lb 1/10/2006 Physician Japan
Primary
Concomitant
Pregnancy Other Serious 9/1/2005 38 Female 1/11/2006 Other Health Professional France
Primary
Secondary
Pleural Effusion Other Serious 10/1/2005 79 Male 1/11/2006 Physician Greece
Primary
Concomitant
Palpitations Other Serious 11/18/2005 Female 1/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 3/1/2005 57 Female 1/17/2006 Physician France
Primary
Concomitant
Drug Exposure During Pregnancy Disability 11/22/2005 38 Female 1/10/2006 Other Health Professional France
Primary
Secondary
Recurrent Cancer Hospitalization 8/22/2005 Male 1/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis E Hospitalization 5/6/2005 57 Female 180 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 12/26/2005 Male 1/19/2006 Physician Japan
Primary
Secondary
Swelling Face Disability 12/9/2005 Male 1/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 9/15/2005 Male 245 lb 1/19/2006 Physician United Kingdom
Primary
Concomitant
Shoulder Pain Hospitalization 10/1/2005 Female 1/19/2006 Other Health Professional France
Primary
Secondary
Myocardial Infarction Hospitalization 4/29/2001 55 Female 148 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Drug Exposure During Pregnancy Disability 10/3/2005 38 Female 1/23/2006 Other Health Professional France
Primary
Secondary
Neoplasm Malignant Hospitalization 3/1/2000 48 Female 150 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Scleroderma Other Serious 11/1/2005 44 Female 1/25/2006 Physician United States
Primary
Concomitant
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 1/25/2006 Physician Belgium
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 7/1/2004 Female 110 lb 1/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 11/25/2005 Male 1/26/2006 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 9/20/2005 Female 157 lb 1/26/2006 Physician United Kingdom
Primary
Concomitant
Laryngitis Hospitalization 9/30/2005 40 Female 1/26/2006 Other Health Professional France
Primary
Concomitant
Rash Pruritic Hospitalization 8/13/2005 Female 123 lb 1/26/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/7/2005 Male 229 lb 1/27/2006 Physician Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/5/2005 Female 1/27/2006 Physician United States
Primary
Concomitant
Adenocarcinoma Death Female 130 lb 1/27/2006 Physician United States
Primary
Concomitant
Peripheral Embolism Other Serious 12/15/2004 Female 1/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 12/26/2005 Male 1/27/2006 Physician Japan
Primary
Secondary
Myelodysplastic Syndrome Other Serious 7/11/2000 Male 1/31/2006 Sweden
Primary
Concomitant
Myocardial Infarction Hospitalization 12/27/2005 44 Female 131 lb 1/23/2006 Other Health Professional United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/25/2003 78 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 9/1/2005 38 Female 2/2/2006 Other Health Professional France
Primary
Secondary
Herpes Zoster Other Serious 2/19/2004 Male 2/2/2006 Physician Sweden
Primary
Concomitant
Skin Fissures Other Serious 1/31/2000 Female 2/2/2006 Sweden
Primary
Concomitant
Amenorrhoea Other Serious 7/1/2005 Female 2/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 1/1/2006 Female 2/3/2006 Physician United States
Primary
Concomitant
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 2/3/2006 Physician Belgium
Primary
Secondary
Concomitant
Multiple Fractures Hospitalization 2/2/2004 64 Female 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/26/2005 Female 97 lb 2/6/2006 Physician United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy Disability 11/22/2005 38 Female 1/31/2006 Other Health Professional France
Primary
Secondary
Leukaemia Other Serious 12/28/2005 Male 2/7/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Drug Exposure During Pregnancy Disability 10/3/2005 38 Female 2/9/2006 Other Health Professional France
Primary
Secondary
Peptostreptococcus Infection Hospitalization 10/25/2005 Female 2/9/2006 Physician United States
Primary
Concomitant
Nephrotic Syndrome Hospitalization 10/24/2005 Male 2/10/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 10/12/2005 Female 2/10/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 6/29/2005 Male 161 lb 2/10/2006 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 7/21/2005 Male 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
Myalgia Life Threatening 1/1/2006 33 Female 2/14/2006 Physician Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/1/2005 Female 95 lb 2/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy Disability 10/3/2005 38 Female 2/15/2006 Other Health Professional France
Primary
Secondary
Amyotrophic Lateral Sclerosis Other Serious 11/9/2005 Female 2/15/2006 Other Health Professional Spain
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 51 Female 2/16/2006 Physician Sweden
Primary
Secondary
Concomitant
Pulmonary Cavitation Other Serious 6/5/2003 Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/22/2005 Male 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/13/2005 44 Male 2/21/2006 Other Health Professional Spain
Primary
Concomitant
Vomiting Other Serious 1/11/2006 Female 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2003 59 Female 128 lb 2/21/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Disability 11/1/2005 Female 156 lb 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/2/2006 60 Female 2/21/2006 Consumer Israel
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 1/1/2005 70 Female 159 lb 2/21/2006 Other Health Professional Switzerland
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 57 Male 225 lb 2/22/2006 Lawyer United States
Primary
Concomitant
Pleural Effusion Other Serious 11/1/2005 71 Female 174 lb 2/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchioloalveolar Carcinoma Other Serious 12/14/2005 56 Male 181 lb 2/19/2006 Physician United States
Primary
Concomitant
Streptococcal Sepsis Hospitalization 7/1/2005 Female 35 lb 2/22/2006 Physician Canada
Primary
Concomitant
Metastatic Renal Cell Carcinoma Hospitalization 9/13/2005 Female 157 lb 2/22/2006 Physician United Kingdom
Primary
Concomitant
Pyrexia Other Serious 9/1/2004 Female 2/22/2006 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 11/1/2005 Male 192 lb 2/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 3/9/2005 47 Male 2/23/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 7/1/2005 Female 2/23/2006 Physician United States
Primary
Concomitant
Leukaemia Other Serious 12/28/2005 Male 2/23/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Keratitis Disability 10/13/2004 Male 2/24/2006 Physician Spain
Primary
Concomitant
Jaundice Hospitalization 11/7/2005 Female 2/24/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 10/1/2005 Female 2/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/31/2005 Female 147 lb 2/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 2/27/2004 49 Male 231 lb 2/27/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2002 57 Male 225 lb 2/27/2006 Physician United States
Primary
Concomitant
Neutropenia Other Serious 11/15/2005 Female 2/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/1999 37 Female 148 lb 2/28/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/5/2006 Female 2/27/2006 Physician Japan
Primary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Amyotrophic Lateral Sclerosis Other Serious 11/9/2005 Female 2/28/2006 Other Health Professional Spain
Primary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
Heart Rate Irregular Female 2/28/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/19/2002 41 Female 150 lb 3/1/2006 Physician United States
Primary
Concomitant
Urticaria Generalised Hospitalization 12/20/2005 9 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/22/2005 Male 3/2/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Shock Syndrome Streptococcal Other Serious 17 Female 108 lb 3/3/2006 United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2005 Male 3/3/2006 Physician Canada
Primary
Concomitant
Juvenile Arthritis Hospitalization 1/30/2006 15 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 14 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/17/2001 68 Male 190 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Streptococcal Infection Life Threatening 1/1/2006 Female 3/6/2006 Consumer Netherlands
Primary
Concomitant
Emotional Disorder Hospitalization 5/1/2004 32 Female 3/7/2006 Lawyer United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/7/2005 Female 3/7/2006 Physician United States
Primary
Concomitant
Paraesthesia Hospitalization 2/28/2006 Female 268 lb 3/9/2006 Consumer United States
Primary
Concomitant
Pain Hospitalization 1/1/2006 Female 3/9/2006 Consumer Australia
Primary
Concomitant
Toxic Shock Syndrome Staphylococcal Other Serious 17 Female 108 lb 3/3/2006 United States
Primary
Concomitant
Uveitis 2/1/2005 Male 3/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 3/9/2006
Primary
Secondary
Concomitant
Swelling Face Other Serious 12/1/2005 Male 3/9/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 12/1/2004 Female 116 lb 3/10/2006 Physician United States
Primary
Concomitant
Renal Cyst Other Serious 7/1/2003 Male 153 lb 3/10/2006 Physician
Primary
Secondary
Nephrotic Syndrome Hospitalization 10/24/2005 Male 3/10/2006 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 7/21/2005 Male 3/10/2006 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization 1/1/2006 74 Female 3/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2004 49 Male 231 lb 3/13/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/18/2006 Female 3/13/2006 Physician United States
Primary
Concomitant
Urticaria 66 Female 132 lb 1/28/2006 United States
Primary
Secondary
Shock Hospitalization 7/1/2005 Female 3/14/2006 Physician Sweden
Primary
Concomitant
Tachycardia Other Serious 12/8/2005 Male 3/14/2006 Other Health Professional France
Primary
Secondary
Pleural Effusion Hospitalization 2/8/2006 71 Female 174 lb 3/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatobiliary Disease Other Serious 3/8/2006 Canada
Primary
Concomitant
Spondylolisthesis Hospitalization 10/29/2005 Female 3/14/2006 Physician Japan
Primary
Concomitant
Tumour Embolism Hospitalization 11/1/2005 Female 130 lb 3/14/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/6/2005 Female 3/14/2006 Consumer Australia
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/5/2006 Female 3/15/2006 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 3/15/2006 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 2/8/2006 71 Female 174 lb 3/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/25/2005 Female 3/17/2006 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 1/1/2006 Female 3/17/2006 Physician Canada
Primary
Concomitant
Pseudocyst Hospitalization 1/1/2006 Female 3/21/2006 Physician United States
Primary
Concomitant
Retinal Vein Occlusion Other Serious 5/1/2005 Female 3/21/2006 Physician United States
Primary
Concomitant
Skin Lesion Other Serious Female 3/10/2006 Physician United States
Primary
Concomitant
Pleuritic Pain Hospitalization 9/13/2005 Female 157 lb 3/22/2006 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 2/1/2006 Female 66 lb 3/22/2006 Physician Korea, Republic Of
Primary
Concomitant
Sepsis Hospitalization 2/10/2006 50 Male 143 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neck Mass Hospitalization 3/1/2006 60 Male 3/22/2006 Physician Israel
Primary
Concomitant
Libido Decreased Disability 1/1/2005 Male 3/24/2006 Physician Finland
Primary
Concomitant
Pleural Effusion Hospitalization 6/4/2005 Male 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Disability 9/20/2005 Female 130 lb 3/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhinitis Other Serious 1/1/2005 Male 3/24/2006 Physician France
Primary
Secondary
Concomitant
Breast Cancer Female Life Threatening Female 3/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pathological Fracture Other Serious 12/16/2005 50 Female 3/27/2006 Other Health Professional Switzerland
Primary
Concomitant
Tuberculosis Hospitalization 1/1/2005 Male 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2006 56 Female 287 lb 3/27/2006 Physician Switzerland
Primary
Concomitant

Drug Data