Actos combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 1/1/1998 58 Female 196 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 2/9/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased 10/1/2005 60 Female 200 lb 1/20/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2002 61 Female 198 lb 3/20/2006 Consumer United States
Primary
Concomitant
Nausea 9/1/2005 47 Female 203 lb 1/20/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2001 63 Female 161 lb 5/10/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/24/2006 52 Female 7/6/2006 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 8/1/2005 Female 7/10/2006 Physician United States
Primary
Concomitant
Weight Decreased 2/1/2006 48 Female 295 lb 4/17/2006 Consumer United States
Primary
Concomitant
Vasculitis Other Serious Female 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 9/21/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 10/2/2006 Other Health Professional United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 3/1/2006 Female 11/3/2006 Physician United States
Primary
Concomitant
Injection Site Pain 10/25/2006 Female 12/14/2006 Consumer United States
Primary
Concomitant
Pelvic Fracture Hospitalization 10/22/2006 Female 220 lb 1/12/2007 Physician United States
Primary
Concomitant
Death Death 2/1/2007 61 Male 2/12/2007 France
Primary
Concomitant
Pancreatitis Hospitalization 11/1/2006 Male 209 lb 3/8/2007 Consumer United States
Primary
Concomitant
Joint Swelling Required Intervention 11/1/2006 61 Female 3/26/2007 United Kingdom
Primary
Secondary
Concomitant
Cardiac Flutter Other Serious 3/1/2003 68 Female 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/1998 Female 8/16/2007 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2003 68 Female 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 5/1/2007 64 Female 240 lb 7/11/2007 Consumer United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 10/22/2007 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2005 67 Male 229 lb 11/9/2007 Consumer United States
Primary
Concomitant
Pericarditis Hospitalization 10/1/2007 Male 310 lb 11/15/2007 Physician United States
Primary
Concomitant
Weight Increased Required Intervention 1/1/2007 70 Female 145 lb 11/26/2007 Consumer United States
Primary
Concomitant
Vulval Cancer Other Serious 1/1/2003 Female 185 lb 12/6/2007 Physician United States
Primary
Concomitant
Weight Increased Female 12/8/2007 Physician United States
Primary
Concomitant
Psoriatic Arthropathy 1/5/2007 Male 330 lb 12/12/2007 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 12/18/2007 Physician United States
Primary
Concomitant
Skin Hyperpigmentation 10/1/2007 48 Male 209 lb 12/21/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2007 53 Female 250 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 1/24/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/13/2008 Female 221 lb 2/1/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/13/2008 Female 221 lb 2/14/2008 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 2/28/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 11/3/2007 Male 3/6/2008 Physician United States
Primary
Concomitant
Paraesthesia 7/1/2005 Male 309 lb 3/14/2008 United States
Primary
Concomitant
Urticaria 10/16/2007 48 Male 209 lb 3/27/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 4/25/2008 60 Male 5/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/25/2008 60 Male 6/3/2008 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 2/24/2008 79 Female 168 lb 5/21/2008 Pharmacist United States
Primary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 7/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 8/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 9/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 10/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain 10/24/2007 Female 240 lb 12/15/2008 Physician United States
Primary
Concomitant
Vision Blurred 10/10/2007 Male 12/17/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/17/2009 Female 140 lb 1/29/2009 United States
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 2/13/2009 Other Health Professional Canada
Primary
Concomitant
Tooth Disorder Hospitalization 8/1/2008 Female 2/17/2009 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 2/24/2009 Other Health Professional Canada
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 3/13/2009 Other Health Professional Canada
Primary
Concomitant
Pain 6/1/2007 Female 155 lb 3/14/2009 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 4/29/2009 Other Health Professional Canada
Primary
Concomitant
Insulin-requiring Type 2 Diabetes Mellitus Other Serious 4/29/2002 50 Female 388 lb 6/1/2009 United States
Primary
Concomitant
Procedural Complication 6/1/2008 Female 230 lb 6/11/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2008 Male 289 lb 6/11/2009 Consumer United States
Primary
Concomitant
Swelling Face 1/1/2009 Female 285 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased 3/1/2009 Male 225 lb 6/12/2009 United States
Primary
Concomitant
Necrotising Retinitis Other Serious 9/1/2008 Female 114 lb 6/17/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/12/2009 45 Female 258 lb 6/15/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Wound Dehiscence Hospitalization 4/2/2009 68 Female 179 lb 8/28/2009 Physician Germany
Primary
Concomitant
Herpes Zoster 6/1/2008 Female 230 lb 9/12/2009 Consumer United States
Primary
Concomitant
Palpitations 6/16/2009 Female 161 lb 9/19/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased 12/1/2008 Female 262 lb 9/19/2009 United States
Primary
Secondary
Concomitant
Injection Site Pain 7/25/2009 Female 250 lb 9/19/2009 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 2/2/2001 30 Female 273 lb 9/23/2009 United States
Primary
Concomitant
Wound Dehiscence Hospitalization 4/2/2009 68 Female 179 lb 9/18/2009 Physician Germany
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Presyncope Hospitalization 5/4/2009 Male 214 lb 11/13/2009 United States
Primary
Concomitant
Sepsis Hospitalization 11/3/2007 Male 11/30/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/13/2008 Female 221 lb 11/30/2009 Physician United States
Primary
Concomitant
Skin Irritation 7/23/2009 Female 12/10/2009 Physician United States
Primary
Concomitant
Hypoglycaemia 85 Female 185 lb 1/30/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 10/1/2007 Male 210 lb 2/10/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 9/11/2009 56 Female 2/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/4/2009 Male 214 lb 2/24/2010 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 10/2/2008 28 Female 112 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Viral Hospitalization 2/27/2010 Female 191 lb 3/8/2010 Consumer United States
Primary
Concomitant
Decreased Appetite Hospitalization 1/23/2010 80 Female 3/12/2010 Physician Japan
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Arthropathy Other Serious 67 Female 3/19/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/2/2008 28 Female 112 lb 4/6/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 4/14/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/4/2009 64 Male 214 lb 5/5/2010 United States
Primary
Concomitant
Weight Increased Other Serious Female 170 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Flushing 5/2/2009 69 Female 214 lb 5/17/2010 United States
Primary
Concomitant
Weight Increased Other Serious 3/1/2010 61 Female 169 lb 5/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/21/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 62 Male 243 lb 5/17/2010 Consumer United States
Primary
Concomitant
Breast Mass Other Serious 1/1/2010 54 Female 6/3/2010 Consumer Canada
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 6/9/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/12/2009 46 Female 258 lb 6/14/2010 United States
Primary
Concomitant
Myositis Other Serious 4/1/2009 60 Female 185 lb 7/6/2010 Physician Australia
Primary
Concomitant
Interacting
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 1/1/2010 62 Male 7/14/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 1/1/2005 63 Male 250 lb 7/26/2010 Consumer United States
Primary
Concomitant
Pneumonia Life Threatening 1/1/2005 63 Male 250 lb 8/13/2010 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/20/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/27/2010 United States
Primary
Secondary
Concomitant
Flushing 1/1/2008 46 Female 350 lb 8/29/2010 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 9/6/2010 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/24/2010 46 Female 154 lb 9/15/2010 Consumer United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 68 Male 9/15/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Type Iv Hypersensitivity Reaction Other Serious 6/1/2010 53 Female 295 lb 10/22/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 10/27/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 11/12/2010 United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 10/19/2010 80 Female 12/6/2010 Physician Japan
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 12/7/2010 United States
Primary
Secondary
Concomitant
Hiatus Hernia Other Serious 9/1/2010 50 Female 170 lb 12/16/2010 Consumer United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 10/19/2010 80 Female 130 lb 12/29/2010 Physician Japan
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 1/23/2010 80 Female 12/31/2010 Physician Japan
Primary
Concomitant
Stress Fracture Hospitalization 4/27/2000 58 Female 138 lb 1/12/2011 United States
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Hospitalization 4/27/2000 58 Female 138 lb 1/18/2011 United States
Primary
Secondary
Concomitant
Injection Site Haematoma 1/1/2009 74 Female 240 lb 1/28/2011 Consumer United States
Primary
Concomitant
Bronchitis Hospitalization Male 240 lb 1/28/2011 Consumer United States
Primary
Concomitant
Poor Quality Drug Administered 2/5/2010 73 Female 189 lb 1/28/2011 Consumer United States
Primary
Concomitant
Nasopharyngitis 8/10/2010 49 Female 1/29/2011 Consumer United States
Primary
Concomitant
Local Swelling 9/2/2010 69 Male 1/30/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 12/30/2010 53 Male 1/30/2011 Consumer United States
Primary
Concomitant
Back Pain Life Threatening 1/1/2005 63 Male 250 lb 2/18/2011 Consumer United States
Primary
Concomitant
Malaise 69 Female 3/8/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 5/24/2010 46 Female 165 lb 3/29/2011 Consumer United Kingdom
Primary
Concomitant
Blood Creatine Increased Hospitalization 11/1/2008 63 Male 243 lb 3/22/2011 Other Health Professional United States
Primary
Concomitant
Stress Fracture Other Serious 4/27/2000 58 Female 138 lb 4/6/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Haematoma Hospitalization 12/27/2010 62 Female 114 lb 5/13/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 12/1/2009 58 Female 137 lb 5/27/2011 Consumer Brazil
Primary
Concomitant
Vomiting Other Serious 3/1/2011 59 Female 6/3/2011 Consumer United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 4/27/2000 58 Female 138 lb 6/29/2011 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 6/20/2011 60 Male 190 lb 7/5/2011 Physician Australia
Primary
Concomitant
Stress Fracture Hospitalization 4/27/2000 58 Female 138 lb 7/15/2011 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/2/2008 28 Female 112 lb 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 1/23/2010 80 Female 7/28/2011 Physician Japan
Primary
Concomitant

Drug Data