Darvocet combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Hospitalization 7/21/2005 Female 149 lb 1/3/2006 Physician United States
Primary
Concomitant
Thirst Other Serious 2/24/2006 Female 172 lb 3/8/2006 Consumer United States
Primary
Concomitant
Paraesthesia Hospitalization 2/28/2006 Female 268 lb 3/9/2006 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/16/2006 54 Female 205 lb 3/16/2006 Physician United States
Primary
Concomitant
Tuberculosis Other Serious Female 196 lb 3/27/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2001 41 Female 150 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 1/1/2000 78 Female 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/30/2003 77 Female 134 lb 4/11/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2000 64 Female 291 lb 4/17/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Life Threatening 9/1/2001 30 Male 187 lb 4/24/2006 Physician United States
Primary
Concomitant
Wrist Fracture Hospitalization 4/20/2000 56 Female 126 lb 5/1/2006 Physician United States
Primary
Concomitant
Respiratory Distress Hospitalization 1/1/2000 78 Female 150 lb 5/3/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2000 47 Female 161 lb 5/8/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 Female 118 lb 5/26/2006 Consumer United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 10/1/2005 Female 5/26/2006 Physician United States
Primary
Concomitant
Cryptococcosis Hospitalization 11/3/2005 72 Male 195 lb 5/30/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Death 2/28/2006 68 Female 6/6/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 11/7/2002 Female 6/9/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 Female 6/26/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 Female 6/28/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 5/3/2006 Female 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Blood Creatinine Increased 5/10/2006 71 Female 6/30/2006 Consumer United States
Primary
Concomitant
Breast Cancer Hospitalization 10/1/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2006 Female 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization Female 110 lb 8/24/2006 Physician United States
Primary
Concomitant
Breast Cancer Hospitalization Female 9/11/2006 Physician United States
Primary
Concomitant
Death Other Serious Female 9/15/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 9/19/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 7/1/2004 Male 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 10/31/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Disorder Other Serious 12/1/2005 Female 9/26/2006 Consumer United States
Primary
Secondary
Concomitant
Death Other Serious Female 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Pseudomonas Infection Other Serious 9/10/2003 Female 200 lb 9/27/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 8/7/2006 48 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Other Serious 8/29/2006 Female 149 lb Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/7/2006 Female 10/13/2006 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 3/1/2006 61 Male 196 lb 8/8/2006 Pharmacist United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 3/30/2006 Female 150 lb 11/3/2006 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 4/1/2006 Female 123 lb 12/7/2006 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection 9/6/2006 75 Female 170 lb 12/22/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/25/2005 54 Male 11/6/2006 Physician United States
Primary
Concomitant
Headache Other Serious 4/13/2006 77 Female 116 lb 5/2/2006 Consumer United States
Primary
Concomitant
Lymphoma Death Female 1/25/2007 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 6/1/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Histoplasmosis Other Serious 12/1/2006 Female 266 lb 4/2/2007 Physician United States
Primary
Concomitant
Death Death 2/8/2007 Female 4/6/2007 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/26/2007 74 Female 5/4/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/26/2007 74 Female 5/17/2007 Consumer United States
Primary
Concomitant
Lower Limb Fracture Other Serious 5/17/2007 Female 5/25/2007 Physician United States
Primary
Concomitant
Procedural Complication Hospitalization 3/1/2007 Female 187 lb 6/14/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/26/2007 74 Female 7/5/2007 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 7/4/2007 40 Female 7/27/2007 Other Health Professional United States
Primary
Concomitant
Femur Fracture Other Serious 6/26/2007 63 Female 200 lb 8/5/2007 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 1/1/2007 40 Female 8/17/2007 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Other Serious Female 252 lb 9/4/2007 United States
Primary
Concomitant
Osteonecrosis Other Serious 8/2/2006 Female 202 lb 9/7/2007 Physician United States
Primary
Concomitant
Pelvic Pain 7/27/2007 63 Female 159 lb 9/26/2007 Consumer United States
Primary
Concomitant
Renal Failure Death 1/1/2007 40 Female 10/2/2007 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Death 7/4/2007 40 Female 10/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/14/2007 Consumer United States
Primary
Concomitant
Oesophagitis Other Serious 54 Female 170 lb 11/26/2007 United States
Primary
Concomitant
Yellow Skin Other Serious 1/1/2005 Male 12/6/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 12/6/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/6/2006 Male 12/6/2007 Physician United States
Primary
Concomitant
Tuberculosis Skin Test Positive Other Serious 12/1/2006 Female 124 lb 12/6/2007 Physician United States
Primary
Concomitant
Basal Cell Carcinoma 4/4/2006 Female 12/8/2007 Physician United States
Primary
Concomitant
Injection Site Pain 3/1/2007 Female 200 lb 12/8/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Disability 8/5/2007 68 Female 234 lb 12/4/2007 Pharmacist United States
Primary
Concomitant
Nasopharyngitis 3/24/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Tuberculosis Gastrointestinal Other Serious 8/8/2005 Male 197 lb 12/13/2007 Physician United States
Primary
Concomitant
Swelling Face 9/1/2007 Female 142 lb 12/13/2007 Physician United States
Primary
Concomitant
Oesophagitis Other Serious 54 Female 170 lb 12/18/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 8/1/2007 Female 173 lb 1/7/2008 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2007 66 Female 202 lb 2/5/2008 Physician United States
Primary
Secondary
Staphylococcal Infection Hospitalization 9/10/2007 66 Female 202 lb 2/20/2008 Physician United States
Primary
Secondary
Staphylococcal Infection Hospitalization 9/10/2007 66 Female 202 lb 2/27/2008 Physician United States
Primary
Secondary
Soft Tissue Disorder Required Intervention 3/1/2003 63 Female 1/17/2008 United States
Primary
Concomitant
Weight Increased Other Serious 60 Female 4/2/2008 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization Female 103 lb 6/18/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/1/2008 73 Female 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Upper 4/19/2008 81 Male 240 lb 6/19/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/1/2008 73 Female 6/19/2008 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 6/27/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/22/2008 Female 103 lb 7/8/2008 Consumer United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Other Serious 12/31/2007 Male 229 lb 7/8/2008 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 7/11/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/1/2008 Female 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 6/1/2008 Female 253 lb 8/19/2008 Other Health Professional United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 9/11/2008 Consumer United States
Primary
Secondary
Concomitant
Psoriasis 12/1/2006 Female 190 lb 9/12/2008 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 10/17/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/30/2008 Female 103 lb 10/23/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 10/29/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 11/5/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/30/2008 Female 103 lb 11/18/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 11/24/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/3/2008 Consumer United States
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Other Serious 9/1/2008 Female 152 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/29/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting 1/1/2008 56 Female 249 lb 12/31/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 260 lb 1/2/2009 Physician United States
Primary
Concomitant
Urticaria Other Serious 12/13/2008 Female 1/6/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 12/1/2008 Female 193 lb 1/30/2009 Physician United States
Primary
Concomitant
Urticaria Other Serious 12/13/2008 Female 2/4/2009 Other Health Professional United States
Primary
Concomitant
Death Death 1/26/2009 Female 134 lb 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 12/1/2008 Female 193 lb 2/13/2009 Physician United States
Primary
Concomitant
Pneumonia Death 1/1/2009 Female 134 lb 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Injection Site Pain 9/1/2007 Female 200 lb 3/14/2009 Consumer United States
Primary
Concomitant
Rash 1/1/2008 Female 210 lb 3/14/2009 Physician United States
Primary
Concomitant
Pneumonia Death 1/1/2009 Female 134 lb 3/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 2/9/2000 50 Female 213 lb 4/14/2009 United States
Primary
Concomitant
Tachypnoea Other Serious 59 Female 5/26/2009 Lawyer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 5/11/2009 Female 150 lb 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia 11/10/2008 Female 6/11/2009 United States
Primary
Concomitant
Injection Site Irritation Female 196 lb 6/11/2009 Physician United States
Primary
Concomitant
Injection Site Irritation 3/2/2009 Female 170 lb 6/11/2009 Consumer United States
Primary
Concomitant
Infected Cyst 1/1/2008 Male 172 lb 6/11/2009 United States
Primary
Concomitant
Injection Site Haematoma Male 190 lb 6/12/2009 Consumer United States
Primary
Concomitant
Sinusitis 5/1/2009 Female 170 lb 6/12/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 5/20/2009 Female 165 lb 6/12/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Death 91 Female 126 lb 6/18/2009 Lawyer United States
Primary
Concomitant
Tachypnoea Other Serious 8/30/2007 59 Female 6/25/2009 Physician United States
Primary
Secondary
Concomitant
Death Death Female 7/7/2009 Consumer United States
Primary
Concomitant
Lung Disorder Hospitalization Female 219 lb 7/13/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/14/2006 Male 200 lb 9/11/2009 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2007 Female 190 lb 9/19/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious 1/1/2007 Female 10/2/2009 United States
Primary
Concomitant
Vomiting Other Serious 2/9/2000 50 Female 213 lb 11/26/2009 United States
Primary
Concomitant
Weight Decreased Disability 1/1/2001 72 Female 95 lb 11/25/2009 United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/31/2009 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/31/2009 Consumer United States
Primary
Secondary
Concomitant
Therapy Regimen Changed Other Serious Female 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Female 180 lb 1/29/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Dose Omission 9/14/2009 Female 158 lb 1/29/2010 United States
Primary
Concomitant
Drug Ineffective 10/1/2009 Female 1/29/2010 United States
Primary
Concomitant
Thyroid Cancer Other Serious 10/1/2009 Female 1/30/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Haematoma 12/1/2009 Male 260 lb 1/30/2010 United States
Primary
Concomitant
Pain Other Serious 7/1/2009 Female 160 lb 1/30/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 3/12/2008 Female 194 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2009 Female 481 lb 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/12/2008 Female 194 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 1/24/2010 Female 2/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Psoriasis 5/27/2009 57 Female 2/22/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 1/1/2009 Female 2/22/2010 Consumer United States
Primary
Concomitant

Drug Data