Loxoprofen Sodium combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Anaphylactoid Reaction Other Serious 8/26/2005 Female 88 lb 4/11/2006 Physician Japan
Primary
Concomitant
Peritonitis Hospitalization 10/11/2006 Female 117 lb 11/7/2006 Physician Japan
Primary
Concomitant
Sarcoidosis Hospitalization 6/27/2006 Female 2/8/2007 Physician Japan
Primary
Concomitant
Sarcoidosis Hospitalization 7/28/2006 Female 3/19/2007 Physician Japan
Primary
Concomitant
Leg Amputation Other Serious 12/26/2003 Male 119 lb 11/20/2007 Physician Japan
Primary
Concomitant
Pulmonary Mass Hospitalization 8/7/2006 Male 160 lb 6/13/2008 Japan
Primary
Concomitant
Pulmonary Mass Hospitalization 8/7/2006 Male 160 lb 6/27/2008 Japan
Primary
Concomitant
Pulmonary Mass Hospitalization 8/7/2006 Male 160 lb 7/11/2008 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 160 lb 8/8/2008 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 160 lb 9/12/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/12/2008 51 Female 9/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 160 lb 10/1/2008 Japan
Primary
Concomitant
Meningitis Other Serious 9/27/2008 Female 93 lb 11/14/2008 Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 167 lb 11/26/2008 Japan
Primary
Concomitant
Speech Disorder Hospitalization 9/27/2008 Female 93 lb 12/11/2008 Japan
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/27/2008 Female 93 lb 12/18/2008 Japan
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/25/2008 Female 93 lb 12/26/2008 Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 12/15/2008 Female 115 lb 1/13/2009 Japan
Primary
Concomitant
Speech Disorder Hospitalization 9/25/2008 Female 93 lb 2/4/2009 Japan
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/25/2008 Female 93 lb 3/10/2009 Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 12/15/2008 Female 115 lb 3/16/2009 Japan
Primary
Concomitant
Speech Disorder Hospitalization 9/25/2008 Female 93 lb 3/18/2009 Japan
Primary
Secondary
Concomitant
Uveitis Other Serious 11/10/2008 Female 123 lb 6/5/2009 Japan
Primary
Concomitant
Pyrexia Other Serious 5/24/2009 Female 6/5/2009 Japan
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/25/2008 Female 93 lb 6/11/2009 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/24/2009 Female 6/11/2009 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/24/2009 Female 6/16/2009 Japan
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/25/2008 Female 93 lb 6/17/2009 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 6/11/2009 Physician Japan
Primary
Secondary
Concomitant
Atypical Mycobacterial Infection Hospitalization 6/1/2009 58 Female 6/11/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 6/19/2009 Consumer Japan
Primary
Secondary
Concomitant
Atypical Mycobacterial Infection Hospitalization 6/1/2009 58 Female 105 lb 6/18/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 5/11/2009 Female 7/8/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 5/11/2009 Female 7/10/2009 Japan
Primary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 7/6/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/11/2009 Female 7/27/2009 Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 5/11/2009 Female 8/4/2009 Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/15/2009 72 Female 114 lb 8/17/2009 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/12/2008 51 Female 8/25/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Splenomegaly Other Serious 7/2/2009 Female 9/4/2009 Japan
Primary
Concomitant
Drug Effect Decreased Hospitalization 6/1/2009 58 Female 105 lb 9/2/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 5/1/2009 Female 139 lb 9/18/2009 Japan
Primary
Secondary
Concomitant
Splenomegaly Life Threatening 7/2/2009 Female 9/21/2009 Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 7/2/2009 Male 116 lb 9/22/2009 Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/15/2009 72 Female 114 lb 9/22/2009 Physician Japan
Primary
Concomitant
Rheumatoid Lung Hospitalization 5/11/2009 Female 10/22/2009 Japan
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 10/14/2009 57 Female 10/23/2009 Physician Japan
Primary
Concomitant
Putamen Haemorrhage Hospitalization 8/11/2009 62 Male 10/23/2009 Japan
Primary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 10/20/2009 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 4/5/2009 Male 10/29/2009 Japan
Primary
Concomitant
Swelling Hospitalization 10/21/2009 30 Female 11/10/2009 Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 7/2/2009 Male 116 lb 11/23/2009 Japan
Primary
Secondary
Concomitant
Purulent Discharge Hospitalization 10/21/2009 30 Female 11/25/2009 Other Health Professional Japan
Primary
Concomitant
Histiocytosis Haematophagic Life Threatening 6/11/2008 51 Female 12/8/2009 Other Health Professional Japan
Primary
Concomitant
Swelling Hospitalization 10/21/2009 30 Female 12/1/2009 Japan
Primary
Concomitant
Acute Myocardial Infarction Death 12/15/2008 Female 115 lb 12/9/2009 Japan
Primary
Concomitant
Rheumatoid Lung Hospitalization 6/3/2009 Female 12/14/2009 Japan
Primary
Secondary
Concomitant
Swelling Hospitalization 10/21/2009 Female 12/12/2009 Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 7/2/2009 Male 116 lb 12/21/2009 Japan
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 11/5/2008 Female 103 lb 12/29/2009 Physician Japan
Primary
Secondary
Concomitant
Swelling Hospitalization 10/21/2009 Female 12/30/2009 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/21/2009 Female 1/19/2010 Japan
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/18/2009 Female 115 lb 2/4/2010 Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 9/22/2009 Female 2/8/2010 Japan
Primary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 2/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 9/22/2009 Female 2/15/2010 Japan
Primary
Concomitant
Tendon Rupture Hospitalization 11/5/2008 Female 103 lb 2/22/2010 Physician Japan
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 5/7/2009 Female 2/23/2010 Japan
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/18/2009 Female 115 lb 2/23/2010 Japan
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 5/7/2009 Female 2/24/2010 Japan
Primary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 5/24/2009 Female 2/26/2010 Japan
Primary
Secondary
Concomitant
Chest X-ray Abnormal Hospitalization 6/1/2009 Female 105 lb 2/10/2010 Japan
Primary
Secondary
Concomitant
Ovarian Neoplasm Other Serious 1/28/2010 Female 3/1/2010 Other Health Professional Japan
Primary
Concomitant
Vulvovaginal Pain Hospitalization 2/16/2010 Female 3/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 3/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Scab Hospitalization 2/16/2010 Female 3/9/2010 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/28/2009 Female 111 lb 3/12/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 3/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 6/1/2009 Female 105 lb 3/16/2010 Consumer Japan
Primary
Secondary
Concomitant
Ovarian Neoplasm Other Serious 1/29/2010 Female 3/16/2010 Other Health Professional Japan
Primary
Concomitant
Ovarian Neoplasm Other Serious 1/29/2010 Female 3/23/2010 Japan
Primary
Concomitant
Scab Hospitalization 2/16/2010 Female 3/22/2010 Japan
Primary
Secondary
Concomitant
Drug Effect Decreased Hospitalization 6/1/2009 58 Female 105 lb 4/1/2010 Japan
Primary
Secondary
Concomitant
Ovarian Neoplasm Other Serious 1/29/2010 60 Female 4/1/2010 Japan
Primary
Concomitant
Cerebral Infarction Other Serious 9/22/2009 78 Female 4/12/2010 Japan
Primary
Concomitant
Benign Ovarian Tumour Other Serious 1/29/2010 60 Female 4/13/2010 Japan
Primary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 4/21/2010 Japan
Primary
Concomitant
Cerebral Infarction Other Serious 9/22/2009 78 Female 4/22/2010 Japan
Primary
Concomitant
Benign Ovarian Tumour Other Serious 1/29/2010 60 Female 4/16/2010 Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 9/22/2009 78 Female 4/28/2010 Japan
Primary
Concomitant
Benign Ovarian Tumour Other Serious 1/29/2010 60 Female 4/29/2010 Japan
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 5/12/2010 63 Female 104 lb 5/25/2010 Physician Japan
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 5/12/2010 63 Female 104 lb 5/26/2010 Physician Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 6/3/2010 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2010 61 Female 5/28/2010 Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2010 61 Female 6/9/2010 Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 6/21/2010 Physician Japan
Primary
Concomitant
Respiratory Arrest Life Threatening 10/14/2009 57 Female 6/22/2010 Physician Japan
Primary
Concomitant
Tumour Necrosis Hospitalization 12/17/2009 67 Female 7/1/2010 Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 4/7/2010 61 Female 7/1/2010 Japan
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Hospitalization 3/8/2007 59 Female 7/12/2010 Physician Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2010 61 Female 7/1/2010 Japan
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Hospitalization 3/8/2007 59 Female 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 4/7/2010 61 Female 7/13/2010 Japan
Primary
Concomitant
Renal Tuberculosis Hospitalization 12/17/2009 67 Female 7/13/2010 Japan
Primary
Concomitant
Fall Hospitalization 12/17/2009 67 Female 7/29/2010 Japan
Primary
Concomitant
Organising Pneumonia Hospitalization 6/23/2010 66 Female 90 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Tuberculin Test Positive Hospitalization 3/23/2010 29 Female 8/6/2010 Japan
Primary
Concomitant
Pyrexia Hospitalization 5/24/2009 64 Female 8/9/2010 Physician Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 6/24/2010 35 Female 110 lb 8/9/2010 Physician Japan
Primary
Secondary
Concomitant
Necrosis Hospitalization 12/17/2009 67 Female 8/6/2010 Other Health Professional Japan
Primary
Concomitant
Threatened Labour Hospitalization 3/23/2010 29 Female 9/10/2010 Japan
Primary
Concomitant
Hodgkin's Disease Stage Iv Other Serious 8/31/2009 73 Female 157 lb 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 5/12/2010 63 Female 104 lb 10/1/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/28/2009 61 Female 111 lb 10/5/2010 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/2/2010 62 Male 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Enterocolitis Infectious Hospitalization 9/1/2010 57 Female 10/20/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/5/2010 39 Male 10/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 10/5/2010 39 Male 10/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Iv Other Serious 8/31/2009 73 Female 157 lb 11/9/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 10/5/2010 39 Male 10/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vertebral Artery Occlusion Other Serious 9/2/2010 62 Male 159 lb 11/12/2010 Physician Japan
Primary
Secondary
Concomitant
Ovarian Adenoma Hospitalization 1/28/2010 60 Female 11/8/2010 Other Health Professional Japan
Primary
Concomitant
Vertebral Artery Occlusion Other Serious 9/2/2010 62 Male 159 lb 12/3/2010 Physician Japan
Primary
Secondary
Concomitant
Enteritis Infectious Hospitalization 9/1/2010 57 Female 12/3/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Mass Hospitalization 9/1/2010 12/13/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Hypertrophy Hospitalization 6/17/2010 40 Female 11/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Peritonitis Life Threatening 12/8/2010 66 Male 117 lb 12/17/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Hypertrophy Hospitalization 6/17/2010 40 Female 12/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Enteritis Infectious Hospitalization 9/1/2010 57 Female 127 lb 12/20/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Complication Hospitalization 12/17/2009 67 Female 12/16/2010 Other Health Professional Japan
Primary
Concomitant
Renal Hypertrophy Hospitalization 6/17/2010 40 Female 12/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Peritonitis Other Serious 12/8/2010 66 Male 117 lb 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Uterine Leiomyoma Hospitalization 5/19/2010 12/15/2010 Other Health Professional Japan
Primary
Concomitant
Gastrointestinal Perforation Other Serious 12/8/2010 66 Male 117 lb 1/4/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/23/2010 1/3/2011 Other Health Professional Japan
Primary
Concomitant
Uterine Leiomyoma Other Serious 5/19/2010 56 Female 12/22/2010 Japan
Primary
Secondary
Concomitant
Deafness Bilateral Life Threatening 1/1/2010 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Vasculitis Hospitalization 4/7/2010 61 Female 12/28/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 1/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Fall Hospitalization 12/17/2007 65 Female 1/18/2011 Other Health Professional Japan
Primary
Concomitant
Condition Aggravated Hospitalization 4/7/2010 61 Female 1/24/2011 Physician Japan
Primary
Concomitant
Constipation Hospitalization 12/17/2009 67 Female 2/7/2011 Other Health Professional Japan
Primary
Concomitant
Condition Aggravated Hospitalization 4/7/2010 61 Female 2/7/2011 Other Health Professional Japan
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 4/7/2010 61 Female 3/7/2011 Other Health Professional Japan
Primary
Concomitant
Uterine Leiomyoma Other Serious 5/19/2010 56 Female 3/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Synovial Cyst Hospitalization 9/1/2010 38 Male 3/21/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Inflammation Hospitalization 10/5/2010 39 Male 3/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data