Methotrexate combined with Risedronate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Resuscitation Life Threatening 11/30/2005 Female 134 lb 1/13/2006 United States
Primary
Concomitant
Sinusitis Life Threatening 7/1/2005 62 Female 1/23/2006 Consumer South Africa
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 1/8/2006 Female 135 lb 1/26/2006 Canada
Primary
Concomitant
Vertigo Hospitalization 8/11/2005 Female 1/27/2006 Italy
Primary
Concomitant
Sinusitis Life Threatening 7/4/2005 62 Female 2/6/2006 Consumer South Africa
Primary
Secondary
Concomitant
Sinusitis Life Threatening 7/4/2005 62 Female 2/16/2006 Consumer South Africa
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 3/9/2006 Consumer Canada
Primary
Concomitant
Postoperative Infection Hospitalization 2/3/2006 Female 225 lb 3/14/2006 Consumer Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 3/23/2006 Physician Canada
Primary
Concomitant
Pneumococcal Sepsis Death 1/24/2006 Female 126 lb 4/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 4/21/2006 Physician Canada
Primary
Concomitant
Postoperative Infection Hospitalization 2/3/2006 Female 225 lb 5/3/2006 Consumer Canada
Primary
Concomitant
Red Blood Cell Abnormality Hospitalization 11/30/2005 85 Male 4/26/2006 Other Health Professional France
Primary
Secondary
Urethral Operation Other Serious 3/30/2006 Female 155 lb 5/5/2006 Consumer Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 5/11/2006 Physician Canada
Primary
Concomitant
Postoperative Infection Hospitalization 2/3/2006 Female 225 lb 5/12/2006 Consumer Canada
Primary
Concomitant
Breast Cancer Required Intervention 2/1/2005 55 Female 159 lb 2/27/2006 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 70 Female 7/6/2006 Physician Greece
Primary
Concomitant
Death Hospitalization 5/3/2006 Female 7/11/2006 Australia
Primary
Concomitant
Tuberculosis Hospitalization 4/5/2005 Female 139 lb 7/11/2006 France
Primary
Concomitant
Tuberculosis Hospitalization 4/5/2005 Female 139 lb 7/18/2006 France
Primary
Concomitant
Urethral Operation Other Serious 3/30/2006 Female 155 lb 7/26/2006 Consumer Canada
Primary
Concomitant
Death Hospitalization 5/3/2006 Female 8/1/2006 Australia
Primary
Concomitant
Pneumococcal Sepsis Death 1/24/2006 Female 126 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Foot Operation Other Serious 7/25/2006 Female 130 lb 8/17/2006 Consumer Canada
Primary
Concomitant
Foot Operation Other Serious 7/25/2006 Female 130 lb 8/21/2006 Consumer Canada
Primary
Concomitant
Foot Operation Other Serious 7/25/2006 Female 130 lb 9/22/2006 Consumer Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Skin Laceration Hospitalization 8/1/2006 Female 90 lb 11/2/2006 Consumer United States
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 9/25/2006 Female 117 lb 11/3/2006 Physician Colombia
Primary
Concomitant
Oesophageal Cancer Metastatic Other Serious 7/30/2006 Female 157 lb 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 6/30/2006 Female 11/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 3/17/2006 Female 206 lb 11/16/2006 Physician United States
Primary
Concomitant
Motor Neurone Disease Other Serious 6/14/2006 66 Male 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage Other Serious 10/1/2006 Male 12/5/2006 Consumer Canada
Primary
Concomitant
Vessel Puncture Site Haemorrhage Other Serious 10/1/2006 Male 12/7/2006 Physician Canada
Primary
Concomitant
Brain Neoplasm Hospitalization 78 Male 159 lb 12/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Brain Neoplasm Hospitalization 78 Male 159 lb 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Other Serious Female 104 lb 12/22/2006 Consumer Canada
Primary
Concomitant
Pain Hospitalization 9/4/2006 Female 209 lb 1/8/2007 Consumer Canada
Primary
Concomitant
Renal Impairment Hospitalization 10/3/2005 71 Female 88 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Headache Other Serious 12/20/2006 Male 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Polyp Other Serious Female 155 lb 1/9/2007 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/23/2005 Female 126 lb 1/19/2007 Consumer United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 11/14/2005 Female 88 lb 1/19/2007 Physician United States
Primary
Secondary
Concomitant
Scab Other Serious 7/14/2006 39 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death Female 128 lb 1/22/2007 France
Primary
Concomitant
Vasculitis Other Serious 1/1/2006 Male 163 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Arthropathy Other Serious Female 150 lb 1/24/2007 Consumer Canada
Primary
Concomitant
Sepsis Other Serious 2/22/2006 Female 128 lb 2/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Colorectal Cancer Metastatic Death Female 130 lb 2/8/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/6/2006 Female 212 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bowen's Disease Other Serious 11/2/2006 Female 179 lb 2/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Depression Hospitalization 9/4/2006 Female 209 lb 2/12/2007 Physician Canada
Primary
Concomitant
Neutropenia Other Serious 12/14/2006 60 Female 128 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Infarction Death 11/13/2006 Female 128 lb 2/16/2007 France
Primary
Concomitant
Pneumonia Hospitalization 12/22/2006 Male 198 lb 2/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 2/22/2006 40 Female 128 lb 2/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pseudoporphyria Other Serious 4/1/2005 55 Female 2/27/2007 United Kingdom
Primary
Concomitant
Sepsis Other Serious 2/22/2006 40 Female 128 lb 3/7/2007 United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 2/22/2006 40 Female 128 lb 3/8/2007 United Kingdom
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Life Threatening 2/11/2007 44 143 lb 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Life Threatening 2/11/2007 44 143 lb 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertebral Injury Hospitalization 9/4/2006 Female 209 lb 3/16/2007 Physician Canada
Primary
Concomitant
Syncope Hospitalization 12/9/2005 Male 161 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wound Other Serious 8/14/2006 Female 137 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sickle Cell Anaemia With Crisis Life Threatening 2/11/2007 44 143 lb 3/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arthropathy Hospitalization Female 200 lb 3/28/2007 Consumer Canada
Primary
Concomitant
Stress Other Serious 12/21/2006 80 Female 81 lb 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/19/2006 Female 126 lb 4/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hydrocephalus Hospitalization 9/1/2006 Female 174 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Endometrial Cancer Other Serious 4/10/2007 Female 110 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 10/15/2006 Female 101 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death Female 123 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Synovial Cyst Hospitalization 1/5/2007 Female 5/11/2007 Physician France
Primary
Secondary
Concomitant
Colorectal Cancer Metastatic Death Female 130 lb 5/17/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/20/2007 Female 132 lb 5/18/2007 Consumer United Kingdom
Primary
Concomitant
Endometrial Cancer Other Serious 4/10/2007 Female 110 lb 5/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 117 lb 6/4/2007 Consumer Canada
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/28/2007 Male 126 lb 6/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Disease Progression Other Serious Female 117 lb 6/22/2007 Consumer Canada
Primary
Concomitant
Diverticulitis Other Serious 6/23/2006 Male 225 lb 7/16/2007 Consumer United Kingdom
Primary
Concomitant
Toothache Other Serious 1/25/2005 41 Female 244 lb 7/16/2007 United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 9/1/2005 80 Female 121 lb 7/17/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 8/1/2006 Female 110 lb 7/27/2007 Canada
Primary
Concomitant
Skin Nodule Hospitalization 8/21/2006 Female 88 lb 8/3/2007 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 31 Female 8/16/2007 Czech Republic
Primary
Concomitant
Vomiting Hospitalization 11/15/2006 Female 183 lb 8/22/2007 United Kingdom
Primary
Concomitant
Spinal Compression Fracture Other Serious 4/16/2007 Female 86 lb 8/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious 9/20/2006 Female 88 lb 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization Female 132 lb 8/30/2007 Canada
Primary
Concomitant
Weight Increased Other Serious 31 Female 9/6/2007 Czech Republic
Primary
Secondary
Concomitant
Spinal Fusion Surgery Other Serious 4/1/2007 Female 132 lb 9/7/2007 Canada
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 8/22/2007 Female 165 lb 9/21/2007 Canada
Primary
Concomitant
Skin Lesion Hospitalization 8/22/2007 Female 165 lb 10/4/2007 Canada
Primary
Concomitant
Rash Maculo-papular Hospitalization 9/13/2007 65 Female 10/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/1/2007 71 Female 10/16/2007 Physician Canada
Primary
Concomitant
Interacting
Tooth Disorder Hospitalization 45 Female 154 lb 10/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/1/2007 71 Female 10/18/2007 Physician Canada
Primary
Concomitant
Interacting
Stomatitis Other Serious Female 135 lb 10/22/2007 Canada
Primary
Concomitant
Weight Decreased Hospitalization 5/2/2007 Female 101 lb 10/30/2007 Italy
Primary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 11/12/2007 Physician Japan
Primary
Concomitant
Wound Treatment Hospitalization 1/25/2005 41 Female 220 lb 11/14/2007 United States
Primary
Secondary
Concomitant
Vasculitis Necrotising Other Serious 7/13/2007 Female 126 lb 11/14/2007 Spain
Primary
Concomitant
Myocardial Ischaemia Hospitalization 5/3/2006 Female 11/16/2007 Australia
Primary
Concomitant
Myocardial Infarction Hospitalization 5/3/2006 Female 11/21/2007 Australia
Primary
Concomitant
Spinal Compression Fracture Other Serious 7/17/2007 Male 218 lb 11/21/2007 United Kingdom
Primary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 11/29/2007 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 5/2/2007 Female 101 lb 11/29/2007 Italy
Primary
Concomitant
Obesity Death 3/28/2007 Female 236 lb 12/3/2007 United Kingdom
Primary
Concomitant
Tuberculosis Hospitalization 4/5/2005 Female 139 lb 12/7/2007 France
Primary
Concomitant
Diarrhoea Hospitalization 5/2/2007 Female 101 lb 12/13/2007 Italy
Primary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 10/1/2006 Female 146 lb 12/14/2007 Other Health Professional United States
Primary
Concomitant
Rhinorrhoea 5/1/2007 Female 133 lb 12/14/2007 Physician United States
Primary
Concomitant
Streptococcal Infection 9/2/2007 Female 150 lb 12/14/2007 United States
Primary
Concomitant
Accidental Exposure 9/9/2007 Female 217 lb 12/14/2007 United States
Primary
Concomitant
Rheumatoid Arthritis 8/1/2007 Female 227 lb 12/14/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 8/1/2007 Female 165 lb 12/14/2007 Consumer United States
Primary
Concomitant
Joint Dislocation Other Serious 8/15/2007 Female 106 lb 12/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Removal Of Foreign Body Other Serious 10/15/2007 Female 106 lb 12/18/2007 Physician United Kingdom
Primary
Concomitant
Spinal Compression Fracture Other Serious 7/17/2007 Male 218 lb 12/20/2007 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 3/20/2007 Female 181 lb 12/21/2007 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 8/10/2007 Female 181 lb 12/28/2007 United Kingdom
Primary
Concomitant
Endometrial Cancer Other Serious 4/10/2007 Female 110 lb 12/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 7/17/2007 Male 218 lb 12/28/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious 4/1/2007 Female 130 lb 1/4/2008 Physician United States
Primary
Concomitant
Oesophageal Cancer Metastatic Other Serious 7/30/2006 Female 157 lb 1/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 12/10/2007 Female 161 lb 1/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Female 79 lb 1/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Other Serious 6/15/2007 Female 20 lb 1/21/2008 United Kingdom
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 1/22/2008 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 5/2/2007 Female 101 lb 1/23/2008 Italy
Primary
Concomitant
Rheumatoid Arthritis Disability Female 1/24/2008 Physician United Kingdom
Primary
Concomitant
Oesophageal Cancer Metastatic Other Serious 3/22/2005 Female 157 lb 1/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Other Serious 1/8/2008 Female 135 lb 1/25/2008 Canada
Primary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 1/31/2008 Physician Japan
Primary
Concomitant
Optic Neuritis Other Serious 7/13/2007 Female 126 lb 2/7/2008 Spain
Primary
Concomitant
Infarction Hospitalization 11/13/2006 Female 128 lb 2/7/2008 France
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 2/11/2008 Physician Japan
Primary
Concomitant
Ovarian Cancer Metastatic Other Serious 8/1/2007 Female 2/13/2008 Spain
Primary
Concomitant
Multi-organ Failure Other Serious 11/13/2007 Female 79 lb 2/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pelvic Fracture Hospitalization 2/5/2007 Female 130 lb 2/18/2008 Canada
Primary
Concomitant
Tuberculosis Other Serious 1/2/2008 65 Female 2/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 11/6/2006 Female 90 lb 2/22/2008 Physician Japan
Primary
Concomitant
Optic Neuritis Other Serious 7/13/2007 Female 126 lb 2/22/2008 Spain
Primary
Concomitant
Throat Tightness Disability Female 128 lb 2/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Compression Fracture Other Serious 7/17/2007 Male 218 lb 2/25/2008 United Kingdom
Primary
Concomitant

Drug Data