Humira combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sciatica Disability 7/26/2005 Female 130 lb 1/4/2006 Spain
Primary
Concomitant
Carpal Tunnel Syndrome Other Serious 12/22/2005 Female 114 lb 1/5/2006 Canada
Primary
Concomitant
Injection Site Erythema Other Serious 10/1/2004 Male 256 lb 1/6/2006 United States
Primary
Concomitant
Hip Fracture Other Serious 1/1/2004 Male 201 lb 1/6/2006 United States
Primary
Concomitant
Tuberculosis Hospitalization 1/1/2005 79 Female 1/9/2006 France
Primary
Secondary
Concomitant
Varicella Hospitalization 3/27/2005 50 Female 1/9/2006 Sweden
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2005 65 Male 1/9/2006 Sweden
Primary
Concomitant
Lung Neoplasm Malignant Death 10/14/2005 Female 1/10/2006 Netherlands
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 12/20/2005 Female 101 lb 1/11/2006 Canada
Primary
Concomitant
Pseudarthrosis Hospitalization 10/1/2005 42 Male 143 lb 1/10/2006 France
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 10/14/2005 68 Female 1/12/2006 Physician Netherlands
Primary
Secondary
Concomitant
Dislocation Of Joint Prosthesis Hospitalization 9/28/2005 Female 108 lb 1/12/2006 United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 11/22/2005 Female 117 lb 1/12/2006 Czech Republic
Primary
Concomitant
Resuscitation Life Threatening 11/30/2005 Female 134 lb 1/13/2006 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 10/21/2004 Female 176 lb 1/13/2006 United Kingdom
Primary
Concomitant
Pyrexia Other Serious 10/1/2005 Male 1/16/2006 Czech Republic
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 10/11/2005 Female 130 lb 1/16/2006 France
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/15/2005 Female 159 lb 1/18/2006 Germany
Primary
Concomitant
Rhinitis Hospitalization 5/15/2005 Female 1/17/2006 Australia
Primary
Concomitant
Myositis Other Serious 9/1/2005 Female 1/18/2006 Belgium
Primary
Concomitant
Respiratory Failure Other Serious 19 Female 121 lb 1/18/2006 Austria
Primary
Concomitant
Peripheral Artery Aneurysm Death 10/22/2005 Male 1/18/2006 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2005 Female 1/18/2006 United Kingdom
Primary
Concomitant
Pyrexia Other Serious 8/1/2005 Female 139 lb 1/19/2006 Belgium
Primary
Concomitant
Peritonitis Hospitalization 11/27/2004 Female 165 lb 1/19/2006 United Kingdom
Primary
Concomitant
Arthralgia Other Serious 2/1/2005 Female 214 lb 1/20/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 Female 120 lb 1/20/2006 Canada
Primary
Concomitant
Renal Disorder Hospitalization 3/17/2002 62 Female 190 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Respiratory Failure Other Serious 19 Female 121 lb 1/24/2006 Austria
Primary
Concomitant
Pyelonephritis Acute Hospitalization 1/9/2006 59 Female 143 lb 1/24/2006 Romania
Primary
Concomitant
Abdominal Abscess Hospitalization 11/8/2004 Female 148 lb 1/25/2006 Netherlands
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Pharyngeal Oedema Other Serious 1/10/2006 Female 280 lb 1/26/2006 Canada
Primary
Concomitant
Femur Fracture Hospitalization 1/8/2006 Female 135 lb 1/26/2006 Canada
Primary
Concomitant
Metastatic Neoplasm Death 1/30/2004 Female 152 lb 1/26/2006 United Kingdom
Primary
Concomitant
Pneumonia Legionella Hospitalization 1/1/2005 Male 119 lb 1/26/2006 Netherlands
Primary
Concomitant
Polyarthritis Hospitalization 4/19/2005 41 Female 1/27/2006 France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 11/22/2005 Female 216 lb 1/27/2006 France
Primary
Concomitant
Vertigo Hospitalization 8/11/2005 Female 1/27/2006 Italy
Primary
Concomitant
Varices Oesophageal Hospitalization 12/26/2005 Female 174 lb 1/27/2006 Finland
Primary
Concomitant
Restlessness Hospitalization 11/18/2005 Female 108 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Trigeminal Neuralgia Hospitalization 9/2/2005 Female 1/30/2006 Denmark
Primary
Concomitant
Syncope Other Serious Male 2/1/2006 United Kingdom
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2006 Female 155 lb 2/1/2006 Canada
Primary
Concomitant
Vomiting Hospitalization 5/27/2005 Female 115 lb 2/2/2006 Italy
Primary
Concomitant
Weight Decreased Death 7/1/2005 Female 2/3/2006 Netherlands
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/1/2005 46 Female 2/3/2006 Brazil
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Death Female 129 lb 2/3/2006 United States
Primary
Concomitant
Neutropenia Hospitalization 7/29/2005 Male 2/3/2006 United Kingdom
Primary
Concomitant
Throat Tightness Other Serious 1/10/2006 Female 280 lb 2/3/2006 Canada
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 8/28/2004 63 Female 2/2/2006 Sweden
Primary
Concomitant
Urinary Retention Death 10/21/2005 Male 192 lb 2/3/2006 United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 1/1/2003 51 Female 2/6/2006 Sweden
Primary
Concomitant
Knee Arthroplasty Hospitalization 7/26/2004 Male 298 lb 2/6/2006 Germany
Primary
Concomitant
Pancreatic Disorder Hospitalization 12/1/2004 63 Female 2/6/2006 Sweden
Primary
Secondary
Concomitant
Psoriasis Other Serious 8/4/2005 Female 120 lb 2/6/2006 Canada
Primary
Concomitant
Knee Arthroplasty Hospitalization 7/19/2005 50 Female 2/7/2006 Germany
Primary
Concomitant
Vasculitis Death 9/27/2005 Female 214 lb 2/7/2006 Italy
Primary
Concomitant
Pseudomonas Infection Hospitalization 12/10/2005 49 Female 238 lb 2/7/2006 France
Primary
Secondary
Polyarthritis Hospitalization 4/19/2005 41 Female 2/7/2006 France
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 1/4/2006 Male 2/7/2006 United Kingdom
Primary
Concomitant
Respiratory Tract Congestion Hospitalization 11/20/2004 Male 170 lb 2/7/2006 United States
Primary
Concomitant
Parkinsonism Disability 12/15/2003 Male 203 lb 2/8/2006 Germany
Primary
Concomitant
Skin Ulcer Hospitalization 1/4/2005 57 Female 143 lb 2/8/2006 Germany
Primary
Concomitant
Tooth Fracture Other Serious 1/24/2006 Female 160 lb 2/8/2006 United States
Primary
Concomitant
Weight Decreased Death 10/14/2005 68 Female 2/9/2006 Physician Netherlands
Primary
Secondary
Concomitant
Sjogren's Syndrome Other Serious 7/20/2004 Female 168 lb 2/9/2006 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Female 2/9/2006 United Kingdom
Primary
Concomitant
Infection Disability 1/1/2005 Female 115 lb 2/9/2006 France
Primary
Secondary
Concomitant
Synovectomy Other Serious 5/24/2005 56 Female 2/9/2006 Germany
Primary
Concomitant
Amyotrophic Lateral Sclerosis Hospitalization 12/1/2004 Male 161 lb 2/9/2006 Belgium
Primary
Concomitant
Nephrolithiasis Hospitalization 2/9/2004 Male 192 lb 2/9/2006 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 3/15/2004 Male 184 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Pleurisy Viral Hospitalization 5/25/2005 Female 126 lb 2/9/2006 United Kingdom
Primary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 Male 203 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 2/9/2006 United Kingdom
Primary
Concomitant
Clostridium Colitis Death 12/15/2003 Female 165 lb 2/9/2006 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death Male 2/10/2006 United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 6/7/2005 53 Female 2/10/2006 Germany
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization Male 180 lb 2/10/2006 Canada
Primary
Concomitant
Depression Other Serious 4/1/2005 Female 185 lb 2/10/2006 United Kingdom
Primary
Concomitant
Joint Arthroplasty Hospitalization 6/7/2005 69 Female 2/10/2006 Germany
Primary
Concomitant
Weight Decreased Hospitalization 5/10/2005 Male 143 lb 2/10/2006 Germany
Primary
Concomitant
Trigeminal Neuralgia Hospitalization 9/2/2005 Female 2/10/2006 Denmark
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 4/27/2004 Female 128 lb 2/10/2006 Germany
Primary
Concomitant
Rheumatoid Arthritis Other Serious 10/15/2004 Female 176 lb 2/10/2006 United Kingdom
Primary
Concomitant
Hypertension Hospitalization 6/11/2004 Female 2/10/2006 Germany
Primary
Concomitant
Respiratory Failure Other Serious 19 Female 121 lb 2/10/2006 Austria
Primary
Concomitant
Tuberculin Test Positive Other Serious 11/22/2005 Female 117 lb 2/10/2006 Czech Republic
Primary
Concomitant
Cerebrovascular Accident Death 11/1/2005 Female 2/10/2006 United States
Primary
Concomitant
Skin Ulcer Hospitalization 2/2/2005 Female 159 lb 2/10/2006 United Kingdom
Primary
Concomitant
Staphylococcal Infection Life Threatening 2/23/2005 Female 196 lb 2/10/2006 United Kingdom
Primary
Concomitant
Knee Arthroplasty Hospitalization 7/19/2005 50 Female 2/13/2006 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 12/1/2005 46 Female 2/13/2006 Physician Brazil
Primary
Secondary
Concomitant
Tuberculosis Other Serious 8/1/2005 Female 139 lb 2/13/2006 Physician Belgium
Primary
Concomitant
Visual Field Defect Other Serious 8/1/2005 40 Female 2/13/2006 Other Health Professional Sweden
Primary
Concomitant
Wound Drainage Hospitalization 1/5/2004 50 Male 2/14/2006 Physician United States
Primary
Concomitant
Weight Increased Life Threatening 4/22/2005 Male 254 lb 2/13/2006 United States
Primary
Concomitant
Diarrhoea Hospitalization 6/8/2004 Male 123 lb 2/15/2006 France
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 11/30/2005 Female 163 lb 2/15/2006 Physician Italy
Primary
Concomitant
Weight Decreased Hospitalization 10/1/2005 Male 88 lb 2/15/2006 Physician United States
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 51 Female 2/16/2006 Physician Sweden
Primary
Secondary
Concomitant
Traumatic Fracture Other Serious 12/7/2005 Female 145 lb 2/16/2006 Physician United States
Primary
Concomitant
Tuberculosis Hospitalization 9/19/2005 19 Female 106 lb 2/16/2006 Other Health Professional France
Primary
Concomitant
Synovectomy Other Serious 5/24/2005 56 Female 2/16/2006 Physician Germany
Primary
Concomitant
Rash Pustular Other Serious Female 142 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Cavitation Other Serious 6/5/2003 Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Varicella Hospitalization 3/27/2005 Female 2/17/2006 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Other Serious 9/27/2004 Male 2/17/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Somnolence Other Serious 50 Male 2/17/2006 Physician Portugal
Primary
Concomitant
Varices Oesophageal Hospitalization 12/26/2005 Female 174 lb 2/17/2006 Finland
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2005 Male 2/17/2006 Other Health Professional Sweden
Primary
Concomitant
Breast Microcalcification Other Serious 12/1/2005 Female 179 lb 2/17/2006 Consumer Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 151 lb 2/17/2006 Physician Germany
Primary
Concomitant
Dyspnoea Other Serious 8/1/2005 52 Female 2/17/2006 Physician Spain
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 8/27/2004 Female 2/17/2006 Other Health Professional Sweden
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 Male 2/17/2006 Consumer Sweden
Primary
Secondary
Concomitant
Lung Infection Hospitalization 1/29/2006 Female 2/17/2006 France
Primary
Concomitant
Peridiverticular Abscess Hospitalization 1/1/2006 Female 155 lb 2/17/2006 Physician Canada
Primary
Concomitant
Tongue Oedema Life Threatening 2/20/2005 Female 2/17/2006 Physician Belgium
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 1/1/2003 51 Female 2/17/2006 Other Health Professional Sweden
Primary
Concomitant
Unevaluable Event Hospitalization 2/4/2006 Male 210 lb 2/17/2006 Consumer Canada
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/21/2006 81 Female 2/20/2006 Physician Spain
Primary
Concomitant
Myocardial Infarction Death 10/15/2005 Male 198 lb 2/20/2006 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/1/2005 Female 110 lb 2/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 57 Male 225 lb 2/22/2006 Lawyer United States
Primary
Concomitant
Orchitis Hospitalization 6/19/2004 Male 181 lb 2/22/2006 France
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 5/27/2005 Female 115 lb 2/23/2006 Italy
Primary
Concomitant
Hypersomnia Disability 11/21/2005 Female 93 lb 2/24/2006 France
Primary
Concomitant
Nervous System Disorder Hospitalization 11/1/2005 Female 2/24/2006 Physician United States
Primary
Concomitant
Lung Disorder Other Serious 5/1/2005 Male 2/27/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2002 57 Male 225 lb 2/27/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 12/15/2005 66 Male 2/14/2006 Sweden
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 2/1/2004 Male 2/28/2006 Physician Norway
Primary
Concomitant
Vertigo Other Serious 10/1/2005 Male 234 lb 2/27/2006 Physician Portugal
Primary
Concomitant
Pancreatic Enzymes Increased Hospitalization 12/10/2005 49 Female 238 lb 2/28/2006 Other Health Professional France
Primary
Secondary
Joint Arthroplasty Hospitalization 5/10/2004 Female 165 lb 2/28/2006 Physician Germany
Primary
Concomitant
Pneumonia Mycoplasmal Hospitalization 53 Female 143 lb 2/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Pseudarthrosis Hospitalization 10/1/2005 42 Male 143 lb 3/1/2006 Other Health Professional France
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 1/1/2005 Female 3/1/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 1/31/2006 50 Female 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious Male 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 61 Male 170 lb 2/27/2006 Physician United States
Primary
Concomitant
Gastric Perforation Hospitalization 11/9/2005 Female 199 lb 3/2/2006 United States
Primary
Concomitant
Cerebrovascular Accident Other Serious Female 3/2/2006 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness Disability 11/30/2005 Female 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 10/3/2005 Female 110 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 11/22/2005 Female 216 lb 3/3/2006 France
Primary
Concomitant
Varices Oesophageal Hospitalization 12/26/2005 Female 174 lb 3/3/2006 Finland
Primary
Concomitant

Drug Data