Lidocaine combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Subarachnoid Haemorrhage Death 9/1/2005 43 Female 1/17/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/1998 58 Female 196 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2002 61 Female 198 lb 3/20/2006 Consumer United States
Primary
Concomitant
Stomatitis Other Serious 7/1/2006 Female 165 lb 10/9/2006 Physician Belgium
Primary
Concomitant
Stomatitis Other Serious 7/12/2006 Female 165 lb 12/12/2006 Physician Belgium
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 3/21/2007 32 Female 134 lb 3/27/2007 United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 6/18/2007 Female 190 lb 6/28/2007 Consumer United States
Primary
Concomitant
Hospitalisation Hospitalization 7/23/2007 62 Female 9/4/2007 Consumer Canada
Primary
Concomitant
Surgery Other Serious 1/1/2007 62 Female 9/11/2007 Consumer Canada
Primary
Concomitant
Tremor Hospitalization 5/8/2000 52 Female 291 lb 9/24/2007 Physician United States
Primary
Concomitant
Vitamin D Decreased Other Serious 12/10/2007 44 Female 174 lb 1/23/2008 Consumer France
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/17/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/22/2008 Physician Japan
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 5/1/2007 Female 198 lb 5/19/2008 Germany
Primary
Secondary
Concomitant
Urticaria 1/1/2006 Female 155 lb 6/12/2008 Other Health Professional United States
Primary
Concomitant
Surgery Other Serious 12/1/2003 Female 106 lb 6/30/2008 United States
Primary
Concomitant
Lymphoma Life Threatening 6/17/2008 Male 185 lb 7/7/2008 Physician United States
Primary
Secondary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 7/15/2008 Physician Japan
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 5/1/2007 Female 198 lb 8/7/2008 Germany
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Life Threatening 5/24/2008 Male 185 lb 8/11/2008 Physician United States
Primary
Secondary
Concomitant
Paraesthesia 7/1/2008 Female 8/29/2008 United States
Primary
Concomitant
Post Herpetic Neuralgia Other Serious 12/1/2006 Female 144 lb 9/5/2008 Physician
Primary
Concomitant
Cellulitis 6/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Injection Site Swelling 6/30/2008 Female 160 lb 9/12/2008 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 7/1/2008 Female 214 lb 9/12/2008 United States
Primary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 5/1/2007 Female 198 lb 11/19/2008 Germany
Primary
Secondary
Concomitant
Stress 3/1/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Vomiting 9/24/2008 Female 117 lb 12/12/2008 Consumer United States
Primary
Concomitant
Urticaria 1/1/2006 Female 155 lb 12/16/2008 Other Health Professional United States
Primary
Concomitant
Neoplasm Malignant Other Serious 5/11/2009 Female 150 lb 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 1/11/2009 Female 6/29/2009 Physician New Zealand
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 2/4/2009 2 Male 29 lb 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/4/2009 2 Male 29 lb 7/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Generalised Oedema Hospitalization 6/23/2009 Female 316 lb 7/21/2009 Physician United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/31/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/4/2009 3 Male 30 lb 8/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 2/4/2009 3 Male 30 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 8/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Pulse Abnormal Hospitalization 9/7/2009 Male 102 lb 9/9/2009 United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 11/6/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Yellow Skin 1/1/2009 Female 105 lb 12/10/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 11/9/2009 3 Male 31 lb 12/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Yellow Skin 9/5/2009 Female 105 lb 1/29/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 65 Male 165 lb 3/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 Female 3/12/2010 Other Health Professional United States
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Anaphylactic Reaction Other Serious 2/16/2010 65 Male 165 lb 3/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 Female 3/25/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 4/9/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 2/4/2009 3 Male 32 lb 5/5/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 5/28/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 6/25/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 7/1/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 8/18/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis 2/1/2010 51 Female 175 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 9/8/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Hyperglycaemia Hospitalization 8/7/2010 13 Male 130 lb 10/18/2010 United States
Primary
Secondary
Concomitant
Blood Bilirubin Abnormal 9/5/2010 13 Male 130 lb 10/22/2010 United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 11/30/2010 United States
Primary
Concomitant
Sinusitis Female 175 lb 11/5/2010 Other Health Professional United States
Primary
Concomitant
Renal Atrophy Other Serious 5/30/1996 48 Female 2/10/2011 United States
Primary
Secondary
Concomitant
Anxiety Other Serious 5/30/1996 48 Female 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 1/1/2003 52 Male 2/14/2011 Other Health Professional United States
Primary
Concomitant
Body Height Decreased Other Serious 1/1/2011 66 Female 135 lb 3/11/2011 Consumer United States
Primary
Concomitant
Angioedema Hospitalization 8 Male 3/1/2011 Pharmacist United States
Primary
Secondary
Concomitant
Bronchitis Other Serious 1/1/2003 52 Male 4/15/2011 Lawyer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2003 52 Male 4/25/2011 Other Health Professional United States
Primary
Concomitant
Infective Thrombosis Hospitalization 12/11/2010 62 Female 129 lb 5/16/2011 Physician United States
Primary
Secondary
Concomitant
Insomnia Death 1/1/2003 52 Male 5/19/2011 Physician United States
Primary
Concomitant
Atelectasis Other Serious 1/1/1999 44 Male 152 lb 5/31/2011 United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization Male 6/15/2011 Physician United States
Primary
Concomitant
Paralysis Flaccid Disability 41 Female 6/8/2011 Other Health Professional China
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2003 52 Male 6/17/2011 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/1/2011 92 Female 162 lb 7/8/2011 Other Health Professional United States
Primary
Concomitant
Lentigo Hospitalization 1/1/2011 55 Male 7/12/2011 Consumer United States
Primary
Secondary
Concomitant
Lentigo Other Serious 1/1/2011 55 Male 7/18/2011 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 41 Female 7/25/2011 Other Health Professional China
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/1999 44 Male 152 lb 7/22/2011 United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/4/2011 China
Primary
Secondary
Concomitant
Sensorimotor Disorder Required Intervention 41 Female 7/29/2011 China
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 1/1/1999 44 Male 152 lb 8/5/2011 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 55 Female 8/2/2011 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2011 55 Male 163 lb 8/11/2011 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 41 Female 8/12/2011 Physician China
Primary
Secondary
Pleural Effusion Hospitalization 11/1/2009 61 Female 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Death 11/17/2009 6 Male 33 lb 9/19/2011 Physician Japan
Primary
Concomitant
Cardiovascular Disorder Hospitalization 9/1/2008 36 Female 9/22/2011 Physician United States
Primary
Secondary
Concomitant
Metastases To Peritoneum Other Serious 11/1/2009 61 Female 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 6/1/2011 56 Female 156 lb 10/4/2011 Physician United States
Primary
Concomitant
Staphylococcal Infection 5/1/2011 72 Female 142 lb 11/1/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2011 56 Female 156 lb 11/29/2011 Consumer United States
Primary
Concomitant
Femur Fracture Hospitalization 11/4/2004 46 Female 246 lb 11/23/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Haematoma Other Serious 5/1/2009 44 Male 12/8/2011 Consumer United States
Primary
Secondary
Concomitant
Hypercapnia Life Threatening 6/16/2008 71 Male 230 lb 12/5/2011 Lawyer United States
Primary
Concomitant
Urticaria 6/7/2011 48 Female 99 lb 10/5/2011 United States
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 11/1/2009 61 Female 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Myositis Hospitalization 1/1/2011 56 Female 156 lb 12/22/2011 Physician United States
Primary
Concomitant
Haemolytic Anaemia Life Threatening 11/17/2009 6 Male 33 lb 12/30/2011 Physician Japan
Primary
Concomitant
Stress Fracture Other Serious 11/4/2004 46 Female 246 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2011 56 Female 156 lb 1/20/2012 Consumer United States
Primary
Concomitant
Arthralgia 6/1/2010 53 Male 195 lb 1/27/2012 Physician United States
Primary
Concomitant
Skin Ulcer 2/1/2011 35 Female 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 5/25/2010 5 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 5/1/2011 12 Female 1/28/2012 Consumer United States
Primary
Concomitant
Back Pain 4/29/2011 58 Female 214 lb 1/28/2012 Consumer United States
Primary
Concomitant
Burning Sensation 8/1/2011 59 Female 1/29/2012 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 6/8/2009 6 Male 33 lb 2/9/2012 Physician Japan
Primary
Concomitant
Injection Site Swelling Other Serious 5/1/2009 41 Male 215 lb 2/17/2012 Consumer United States
Primary
Secondary
Concomitant
Headache 10/13/2011 60 Female 156 lb 12/20/2011 United States
Primary
Concomitant
Benign Uterine Neoplasm Other Serious 1/1/2012 51 Female 172 lb 2/29/2012 Other Health Professional United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 6/8/2009 6 Male 33 lb 3/9/2012 Physician Japan
Primary
Concomitant
Pulmonary Embolism Other Serious 7/15/2011 52 Female 185 lb 3/16/2012 Consumer Netherlands
Primary
Secondary
Concomitant
Bone Marrow Oedema Other Serious 1/1/1999 44 Male 152 lb 4/9/2012 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 2/24/2012 11 Female 116 lb 5/2/2012 Physician United States
Primary
Concomitant
Nausea Other Serious 3/1/2011 71 Female 5/3/2012 Physician United Kingdom
Primary
Concomitant
Bradycardia Hospitalization 67 Female 5/11/2012 Physician United States
Primary
Secondary
Concomitant
Nervousness Other Serious 1/1/2012 51 Female 172 lb 5/17/2012 Other Health Professional United States
Primary
Concomitant
Hypertension Death 2/24/2012 11 Female 116 lb 5/22/2012 Other Health Professional United States
Primary
Concomitant
Gallbladder Necrosis Death Male 6/4/2012 Physician United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 4/7/2012 Female 162 lb 6/7/2012 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2009 45 Female 216 lb 6/14/2012 Consumer United States
Primary
Concomitant
Breath Sounds Abnormal Disability Female 226 lb 6/8/2012 Lawyer United States
Primary
Concomitant
Haematocrit Decreased Hospitalization 4/27/2012 75 Female 6/21/2012 Physician United States
Primary
Concomitant
Adverse Reaction Hospitalization 1/1/2011 56 Female 148 lb 7/5/2012 Physician United States
Primary
Concomitant
Arthropathy Other Serious 5/1/2007 41 Female 8/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Hospitalization 4/27/2012 75 Female 12/27/2012 Physician Us
Primary
Concomitant
Sepsis Death 4/6/2012 44 Female 162 lb 10/30/2012 Physician Ca
Primary
Concomitant
Skin Infection Hospitalization 2012 10 Female 99 lb 12/20/2012 Consumer Us
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 7/27/2012 13 Female 271 lb 11/9/2012 Other Health Professional Us
Primary
Secondary
Concomitant

Drug Data