Methotrexate combined with Reclast

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Oedema Hospitalization Female 1/29/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 2/4/2008 Female 194 lb 2/27/2008 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 1/1/2008 86 Female 3/5/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 1/1/2008 86 Female 3/11/2008 Physician United States
Primary
Concomitant
Wheezing Other Serious 3/29/2008 81 Female 135 lb 3/31/2008 Physician United States
Primary
Concomitant
Transplant Rejection Other Serious 3/1/2008 65 Female 119 lb 4/21/2008 Physician United States
Primary
Concomitant
Transplant Rejection Other Serious 3/1/2008 65 Female 119 lb 5/6/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 1/1/2008 86 Female 5/9/2008 Physician United States
Primary
Concomitant
Troponin Increased Other Serious 7/29/2008 Female 250 lb 8/6/2008 Physician United States
Primary
Concomitant
Troponin Increased Other Serious 7/29/2008 Female 250 lb 9/9/2008 Physician United States
Primary
Concomitant
Transplant Rejection Other Serious 3/1/2008 65 Female 119 lb 9/15/2008 Physician United States
Primary
Concomitant
Troponin Increased Other Serious 7/29/2008 Female 250 lb 10/20/2008 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 7/1/2007 Male 203 lb 11/3/2008 Other Health Professional United States
Primary
Concomitant
Medical Device Removal Other Serious 10/4/2007 72 Female 176 lb 11/20/2008 Greece
Primary
Secondary
Concomitant
Troponin Increased Other Serious 7/29/2008 Female 250 lb 12/4/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 1/8/2009 Physician United States
Primary
Concomitant
Osteonecrosis Required Intervention 12/8/2008 Female 111 lb 1/13/2009 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 1/6/2009 Female 181 lb 1/19/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 1/23/2009 Physician United States
Primary
Concomitant
Transplant Rejection Other Serious 3/1/2008 65 Female 119 lb 1/30/2009 Physician United States
Primary
Concomitant
Mouth Ulceration Other Serious 12/11/2008 63 Female 208 lb 3/10/2009 Physician United States
Primary
Concomitant
Removal Of Foreign Body Other Serious 11/1/2008 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious 12/11/2008 63 Female 208 lb 3/25/2009 Physician United States
Primary
Concomitant
Fall Death 11/17/2008 79 Female 106 lb 3/26/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 3/7/2009 Female 4/13/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 4/30/2009 Physician United States
Primary
Concomitant
Carpal Tunnel Syndrome Other Serious Female 130 lb 5/1/2009 Consumer United States
Primary
Concomitant
Syncope Life Threatening 4/1/2009 Female 132 lb 5/17/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/7/2009 Female 6/8/2009 Physician United States
Primary
Concomitant
Removal Of Foreign Body Other Serious 11/1/2008 Female 7/6/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/1/2009 Female 119 lb 7/16/2009 Physician United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 7/1/2009 Female 122 lb 7/17/2009 United States
Primary
Concomitant
Renal Failure Other Serious 7/1/2009 Female 7/17/2009 Physician United States
Primary
Secondary
Rotator Cuff Syndrome Other Serious 7/1/2009 Female 122 lb 7/20/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/1/2009 Female 119 lb 8/13/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 7/1/2009 Female 119 lb 8/21/2009 Physician United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious Female 150 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 9/9/2009 Female 122 lb 11/9/2009 United States
Primary
Concomitant
Vomiting Hospitalization 9/9/2009 Female 122 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Tooth Loss Other Serious 12/30/2008 Female 11/20/2009 United States
Primary
Concomitant
Bowen's Disease Other Serious Female 150 lb 11/30/2009 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 11/1/2009 Female 12/1/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/29/2009 Female 230 lb 12/15/2009 Physician United States
Primary
Concomitant
Confusional State Other Serious 8/1/2009 Female 99 lb 1/12/2010 Physician United States
Primary
Concomitant
Ear Disorder Other Serious Female 1/25/2010 Consumer United States
Primary
Concomitant
Death Death 2/25/2009 Female 1/25/2010 Physician United States
Primary
Concomitant
Ear Disorder Other Serious 6/1/2009 Female 2/5/2010 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 10/20/2009 70 Female 132 lb 2/12/2010 Physician United States
Primary
Concomitant
Confusional State Other Serious 8/1/2009 Female 99 lb 3/5/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/9/2010 42 Female 126 lb 3/9/2010 Pharmacist United States
Primary
Concomitant
Herpes Zoster Other Serious 12/17/2009 69 Female 3/17/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 3/1/2010 81 Male 234 lb 4/8/2010 Physician United States
Primary
Concomitant
Herpes Zoster Other Serious 12/17/2009 68 Female 120 lb 4/12/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 4/29/2010 Consumer United States
Primary
Concomitant
Rash Generalised Hospitalization 3/1/2009 47 Female 132 lb 5/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 5/7/2010 Physician United States
Primary
Concomitant
Death Death 12/9/2009 95 Female 100 lb 5/10/2010 United States
Primary
Concomitant
Death Death 12/29/2009 80 Female 6/16/2010 United States
Primary
Concomitant
Death Death Female 100 lb 6/16/2010 United States
Primary
Concomitant
Retinal Vein Occlusion Other Serious 7/1/2010 62 Female 195 lb 8/17/2010 Consumer United States
Primary
Concomitant
Frequent Bowel Movements 1/1/2009 71 Female 125 lb 8/27/2010 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious Female 104 lb 9/18/2010 Physician United States
Primary
Concomitant
Spinal Operation Hospitalization Female 140 lb 9/27/2010 Consumer United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 8/25/2010 50 Female 104 lb 10/1/2010 Physician United States
Primary
Concomitant
Pneumonia Death 9/24/2010 75 Female 10/21/2010 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 2/14/2010 60 Female 10/22/2010 Consumer United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 10/28/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 11/16/2010 United States
Primary
Concomitant
Urticaria Other Serious 10/19/2010 46 Female 11/25/2010 Physician United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 11/29/2010 Physician United States
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 4/1/2010 81 Female 127 lb 12/13/2010 Physician United States
Primary
Concomitant
Hip Fracture Hospitalization 1/1/2010 78 Female 174 lb 12/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 8/25/2010 50 Female 104 lb 12/13/2010 Physician United States
Primary
Concomitant
Nasopharyngitis Other Serious 1/1/2010 73 Female 153 lb 12/17/2010 Physician United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/1/2010 81 Female 127 lb 12/17/2010 Physician United States
Primary
Concomitant
Hip Fracture Other Serious 11/6/2010 78 Female 148 lb 12/21/2010 United States
Primary
Secondary
Concomitant
Limb Asymmetry Hospitalization 4/1/2010 68 Female 138 lb 12/27/2010 Consumer United States
Primary
Concomitant
Blood Creatine Abnormal Other Serious 10/19/2010 46 Female 1/12/2011 Physician United States
Primary
Concomitant
Pain 1/9/2010 60 Female 110 lb 1/28/2011 Consumer United States
Primary
Concomitant
Stress Fracture Female 157 lb 1/28/2011 United States
Primary
Concomitant
Weight Decreased 11/1/2009 73 Female 1/28/2011 Consumer United States
Primary
Concomitant
Injection Site Urticaria 3/26/2010 61 Female 140 lb 1/28/2011 Consumer United States
Primary
Concomitant
Epistaxis 4/23/2010 61 Female 140 lb 1/29/2011 Consumer United States
Primary
Concomitant
Blood Pressure Increased 8/1/2010 57 Male 270 lb 1/29/2011 Consumer United States
Primary
Concomitant
Blood Pressure Increased 1/1/2009 86 Male 170 lb 1/30/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 4/1/2010 Female 2/25/2011 Consumer United States
Primary
Concomitant
Headache Disability 6/1/2010 71 Female 152 lb 3/9/2011 Physician United States
Primary
Concomitant
Fall Other Serious Female 3/9/2011 Consumer United States
Primary
Concomitant
Dyskinesia 9/27/2010 68 Female 3/25/2011 Consumer United States
Primary
Concomitant
Femur Fracture Other Serious 11/1/2010 74 Female 4/4/2011 Physician United States
Primary
Concomitant
Arthralgia Other Serious Female 4/8/2011 Consumer United States
Primary
Concomitant
Influenza Like Illness Life Threatening Female 4/11/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 9/16/2010 54 Female 131 lb 4/21/2011 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 58 Female 179 lb 4/22/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 1/1/1999 68 Female 5/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 4/9/2011 71 Female 119 lb 5/26/2011 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization 4/9/2011 71 Female 119 lb 5/26/2011 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/4/2011 54 Female 6/2/2011 Physician United States
Primary
Concomitant
Cognitive Disorder Other Serious Female 6/3/2011 Pharmacist United States
Primary
Concomitant
Joint Swelling Other Serious 1/1/1999 68 Female 6/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 4/19/2011 69 Female 128 lb 6/7/2011 Physician United States
Primary
Concomitant
Influenza Hospitalization 3/3/2011 57 Female 6/9/2011 Consumer United States
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious 3/1/2011 74 Female 6/10/2011 United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization Male 6/15/2011 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 68 Female 7/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 5/16/2011 66 Female 7/5/2011 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 4/19/2011 69 Female 128 lb 7/18/2011 Physician United States
Primary
Concomitant
Oral Pain Other Serious 5/4/2011 54 Female 150 lb 8/2/2011 Physician United States
Primary
Concomitant
Tenderness Hospitalization 3/15/2011 71 Female 304 lb 8/10/2011 Physician United States
Primary
Concomitant
Pemphigoid Other Serious 9/27/2011 67 Female 10/6/2011 Physician United States
Primary
Concomitant
Iatrogenic Injury Other Serious 6/4/2010 45 Female 246 lb 10/4/2011 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 10/1/2011 77 Female 10/20/2011 Other Health Professional United States
Primary
Concomitant
Arthropathy Other Serious Female 10/20/2011 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization Female 10/26/2011 Consumer United States
Primary
Concomitant
Injection Site Pruritus 6/27/2011 82 Female 88 lb 11/2/2011 Other Health Professional United States
Primary
Concomitant
Pelvic Fracture Hospitalization 9/1/2011 Female 11/3/2011 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 10/3/2011 77 Female 117 lb 11/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 9/1/2008 61 Female 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Blood Cholesterol Increased Other Serious 1/1/2004 57 Female 11/11/2011 Lawyer United States
Primary
Concomitant
Cognitive Disorder Other Serious Female 11/14/2011 Pharmacist United States
Primary
Concomitant
Gastrointestinal Tract Irritation Other Serious 11/4/2004 39 Female 246 lb 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Infection 4/1/2011 78 Male 11/17/2011 Consumer United States
Primary
Concomitant
Femur Fracture Hospitalization 11/4/2004 46 Female 246 lb 11/23/2011 Physician United States
Primary
Secondary
Concomitant
Balance Disorder Hospitalization 1/1/2009 85 Female 149 lb 12/7/2011 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Perforation Other Serious 12/12/2011 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization Female 141 lb 12/16/2011 Physician United States
Primary
Concomitant
Stress Fracture Other Serious 11/4/2004 46 Female 246 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fluid Retention Other Serious 1/1/2006 68 Female 120 lb 1/6/2012 Consumer United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 75 Female 11/28/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 1/23/2012 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/29/2011 68 Female 235 lb 1/26/2012 Physician United States
Primary
Secondary
Concomitant
Device Malfunction 4/7/2011 77 Female 1/28/2012 Consumer United States
Primary
Concomitant
Arthritis Female 1/28/2012 Consumer United States
Primary
Concomitant
Ankle Fracture 1/1/2010 46 Female 130 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain Female 123 lb 1/28/2012 Consumer United States
Primary
Concomitant
Cataract Other Serious 1/1/2006 55 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 6/1/2011 46 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema 5/1/2011 66 Female 1/28/2012 Consumer United States
Primary
Concomitant
Tongue Haemorrhage Other Serious Female 1/31/2012 Physician United States
Primary
Concomitant
Flushing Other Serious Female 160 lb 2/2/2012 Consumer United States
Primary
Concomitant
Musculoskeletal Discomfort Other Serious 80 Female 153 lb 2/2/2012 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage Other Serious 11/1/2011 57 Female 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 4/1/2011 70 Female 119 lb 2/29/2012 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2008 62 Female 110 lb 3/2/2012 Physician United States
Primary
Concomitant
Impaired Healing Other Serious 11/1/2011 57 Female 124 lb 3/2/2012 Physician United States
Primary
Secondary
Concomitant
Death Death Female 3/27/2012 Consumer United States
Primary
Concomitant
Night Sweats Other Serious 3/11/2012 58 Female 5/8/2012 Consumer United States
Primary
Concomitant
Walking Aid User Hospitalization 2/14/2010 60 Female 5/3/2012 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 3/11/2012 58 Female 5/15/2012 Consumer United States
Primary
Concomitant

Drug Data