Methotrexate combined with Tramadol Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Other Serious 10/20/2005 Male 152 lb 1/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Arthritis Other Serious 10/15/2005 Female 176 lb 1/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious Female 1/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Disability 12/9/2005 Male 1/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 9/15/2005 Male 245 lb 1/19/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Death 7/13/2005 57 Female 159 lb 1/13/2006 Physician Germany
Primary
Concomitant
Restlessness Hospitalization 11/18/2005 Female 108 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Amenorrhoea Other Serious 7/1/2005 Female 2/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Death 78 Female 2/17/2006 Germany
Primary
Concomitant
Folliculitis Other Serious 9/14/2005 Female 293 lb 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 10/3/2005 Female 110 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 10/3/2005 Female 110 lb 3/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 3/9/2006
Primary
Secondary
Concomitant
Peritoneal Tuberculosis Hospitalization 71 Female 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Peritoneal Tuberculosis Hospitalization 10/17/2005 Female 185 lb 3/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Peritoneal Tuberculosis Hospitalization 10/17/2005 Female 185 lb 3/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 2/16/2005 67 Female 132 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 4/23/2005 Female 207 lb 3/29/2006 Consumer United Kingdom
Primary
Concomitant
Peritoneal Tuberculosis Other Serious 10/17/2005 Female 185 lb 4/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/10/2006 61 Male 4/4/2006 Consumer United Kingdom
Primary
Concomitant
Peritoneal Tuberculosis Hospitalization 10/17/2005 Female 185 lb 4/4/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Migraine Other Serious 7/7/2004 Female 152 lb 4/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Shock Other Serious 78 Female 4/7/2006 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/15/2005 Male 245 lb 4/11/2006 Physician United Kingdom
Primary
Concomitant
Grand Mal Convulsion Hospitalization 2/1/2006 Female 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 4/24/2006
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 78 Female 4/12/2006 Physician Germany
Primary
Concomitant
Platelet Production Decreased Hospitalization 4/4/2006 60 Male 169 lb 4/27/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 10/3/2005 Female 110 lb 5/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dysgeusia 11/30/2005 66 Female 2/21/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 6/1/2004 48 Female 163 lb 5/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Erythema Nodosum Other Serious 5/1/2006 76 Female 187 lb 5/17/2006 Physician United States
Primary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 5/23/2006 Consumer United Kingdom
Primary
Concomitant
Unintended Pregnancy Hospitalization 3/24/2006 Female 110 lb 6/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 3/31/2006 Male 6/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Colitis Hospitalization 11/1/2005 Female 6/9/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 12/11/2005 Female 212 lb 6/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Migraine Other Serious 3/10/2006 Female 155 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 3/27/2006 Male 165 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious 3/26/2006 Female 143 lb 6/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 3/22/2006 Female 183 lb 6/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dysgeusia 11/30/2005 66 Female 5/19/2006 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Hospitalization 3/22/2006 Female 183 lb 7/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Male 119 lb 7/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 5/31/2005 Male 119 lb 7/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 64 Male 175 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Death 7/6/2004 Male 126 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious 1/4/2006 Male 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lung Infiltration Hospitalization 1/27/2006 Female 8/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/14/2005 Male 168 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 5/11/2006 Male 156 lb 8/11/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Death 10/28/2005 Female 88 lb 8/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 5/19/2005 Male 119 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/25/2006 Female 226 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteoporotic Fracture Other Serious 4/1/2006 Male 168 lb 8/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Pain Upper Hospitalization 5/10/2005 Female 194 lb 8/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteoarthritis Disability 6/15/2005 Female 8/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Tuberculosis Other Serious 10/17/2005 Female 185 lb 8/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 4/13/2006 Female 126 lb 9/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2006 Female 331 lb 9/7/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Tachycardia Other Serious 7/24/2006 Female 106 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 3/15/2006 Female 10/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 3/9/2005 Female 10/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 12/15/2001 Female 100 lb 10/16/2006 Physician United States
Primary
Concomitant
Mesenteric Vascular Insufficiency Other Serious 5/14/2002 Female 215 lb 10/16/2006 Physician United States
Primary
Concomitant
Metastatic Neoplasm Other Serious 7/28/2006 Male 174 lb 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Other Serious 4/24/2006 Male 163 lb 11/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Joint Effusion Other Serious 10/2/2006 Female 121 lb 11/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Uveitis Disability 1/15/2006 Male 141 lb 11/10/2006 Physician United Kingdom
Primary
Concomitant
Hemiparesis Other Serious 5/3/2006 Female 192 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Throat Cancer Other Serious 8/3/2006 Male 187 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gout Hospitalization 3/17/2006 Male 225 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hemiparesis Other Serious 5/3/2006 Female 192 lb 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 9/24/2004 45 Female 168 lb 11/21/2006 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2004 66 Female 11/22/2006 France
Primary
Secondary
Concomitant
Throat Tightness Life Threatening 10/13/2006 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subcutaneous Abscess Other Serious 1/1/2006 Female 207 lb 12/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2006 Male 143 lb 12/8/2006 Physician France
Primary
Concomitant
Vascular Bypass Graft Other Serious 7/21/2005 Male 216 lb 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Bronchitis Hospitalization 6/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 5/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Male 12/1/2006 Pharmacist United Kingdom
Primary
Concomitant
Death Other Serious Male 119 lb 12/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious 11/12/2006 Male 216 lb 12/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 3/12/2004 57 Female 137 lb 12/29/2006 Physician France
Primary
Secondary
Concomitant
Death Other Serious 11/12/2006 Male 216 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Hospitalization 10/15/2006 Male 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 11/28/2006 55 Female 176 lb 1/18/2007 Physician France
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 11/21/2006 Male 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 3/22/2006 Female 183 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Death Female 128 lb 1/22/2007 France
Primary
Concomitant
Non-hodgkin's Lymphoma Death 8/31/2006 Male 168 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 1/1/2006 Female 1/25/2007 Physician United States
Primary
Secondary
Concomitant
Hepatitis B Other Serious Female 234 lb 1/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Tuberculosis Other Serious 10/17/2005 Female 185 lb 2/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Other Serious 10/15/2004 Male 220 lb 2/7/2007 Consumer United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/1/2006 Female 154 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Macrocytosis Hospitalization 12/21/2006 Female 115 lb 2/9/2007 Physician United Kingdom
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2007 Male 87 lb 2/9/2007 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 12/18/2005 Male 168 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 10/10/2006 Male 168 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/1/2006 Male 87 lb 2/16/2007 Other Health Professional United States
Primary
Concomitant
Infarction Death 11/13/2006 Female 128 lb 2/16/2007 France
Primary
Concomitant
Rheumatoid Arthritis Life Threatening 6/1/2006 51 Female 115 lb 2/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vasculitic Rash Disability 11/1/2005 60 Female 148 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Subcutaneous Abscess Other Serious 1/1/2006 Female 207 lb 2/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 7/21/2005 Male 216 lb 2/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/1/2006 Male 87 lb 3/19/2007 Physician United States
Primary
Concomitant
Subcutaneous Abscess Other Serious 3/1/2006 37 Female 207 lb 3/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Embolus Hospitalization 12/1/2005 Female 3/26/2007 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 9/30/2005 Female 207 lb 3/30/2007 Consumer United Kingdom
Primary
Concomitant
Subcutaneous Abscess Other Serious 3/1/2006 37 Female 207 lb 3/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritoneal Tuberculosis Other Serious 10/17/2005 Female 185 lb 4/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Abscess Hospitalization 3/7/2006 37 Female 207 lb 4/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 9/29/2005 Female 115 lb 4/12/2007 Consumer United Kingdom
Primary
Concomitant
Subcutaneous Abscess Other Serious 3/1/2006 37 Female 207 lb 4/7/2007 United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 4/18/2007 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious Male 216 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Infusion Related Reaction Other Serious 11/24/2006 Female 134 lb 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious 3/15/2007 Female 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Abscess Other Serious 1/1/2006 Female 207 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/1/2007 Female 118 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 2/6/2006 Male 187 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2006 46 Female 117 lb 4/30/2007 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/18/2007 Female 181 lb 5/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pericardial Effusion Life Threatening 12/1/2006 50 Female 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 4/20/2006 Male 168 lb 5/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Disability 57 Female 154 lb 5/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 2/22/2007 38 Female 5/8/2007 Consumer United States
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 5/17/2007 Physician United States
Primary
Concomitant
Metastatic Renal Cell Carcinoma Other Serious 1/1/1999 Female 141 lb 5/18/2007 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 11/16/2006 Female 123 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 4/1/2007 Male 187 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vitritis Hospitalization 3/15/2007 Female 123 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cholecystitis Hospitalization 2/5/2007 54 Female 5/30/2007 Consumer Poland
Primary
Concomitant
Rheumatoid Arthritis Disability 9/1/2006 65 Female 5/24/2007 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Disability 9/1/2006 65 Female 5/26/2007 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Disability 9/1/2006 65 Female 5/28/2007 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Disability 9/1/2006 65 Female 5/31/2007 United Kingdom
Primary
Concomitant
Vitritis Other Serious 3/13/2007 Female 101 lb 6/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pericardial Effusion Life Threatening 12/1/2006 50 Female 6/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 9/1/2006 71 Female 213 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Life Threatening 9/1/2006 71 Female 213 lb 6/13/2007 United Kingdom
Primary
Secondary
Concomitant
Pericarditis Hospitalization 3/6/2006 Female 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/9/2007 Female 150 lb 6/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pericardial Effusion Hospitalization 3/6/2006 Female 6/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 11/20/2006 Female 132 lb 6/21/2007 Physician United Kingdom
Primary
Concomitant

Drug Data