Methotrexate combined with Pantoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Orthostatic Hypotension Other Serious 12/13/2005 63 Female 1/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Hospitalization 10/20/2005 71 Male 1/11/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Ovarian Cancer Other Serious 6/1/2005 Female 1/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 1/4/2005 57 Female 143 lb 2/8/2006 Germany
Primary
Concomitant
Impaired Healing Hospitalization 5/4/2005 65 Male 2/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastric Perforation Hospitalization 11/9/2005 Female 199 lb 3/2/2006 United States
Primary
Concomitant
Infection Life Threatening 7/1/2003 79 Male 179 lb 3/7/2006 Physician Austria
Primary
Concomitant
Pneumonia Death 2/1/2006 Male 289 lb 3/7/2006 Physician United States
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 10/20/2005 71 Male 3/17/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 12/1/2005 58 Male 132 lb 4/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pemphigus Hospitalization 9/28/2005 Female 88 lb 5/1/2006 Physician Austria
Primary
Concomitant
Tachycardia Other Serious 12/1/2005 58 Male 132 lb 5/3/2006 Other Health Professional France
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 5/8/2006 Physician Germany
Primary
Concomitant
Pneumonia Staphylococcal Other Serious 1/1/2006 Male 289 lb 5/11/2006 Physician United States
Primary
Concomitant
Stomach Discomfort Required Intervention 1/1/2005 40 Female 136 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 6/7/2006 Physician Germany
Primary
Concomitant
Basal Cell Carcinoma Other Serious 9/29/2006 Female 123 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 3/1/2007 Female 118 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Disability 9/20/2007 66 Male 148 lb 1/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 12/1/2007 Female 1/28/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 80 lb 2/1/2008 Canada
Primary
Concomitant
Gastrointestinal Disorder Hospitalization Male 2/8/2008 Consumer Germany
Primary
Concomitant
Vestibular Disorder Other Serious 1/1/2005 Female 2/15/2008 Other Health Professional Canada
Primary
Concomitant
Subcutaneous Nodule Hospitalization 10/25/2005 Male 2/15/2008 France
Primary
Concomitant
Wheezing Other Serious 2/14/2008 Female 76 lb 2/22/2008 Canada
Primary
Concomitant
Pain 11/12/2007 Female 228 lb 6/12/2008 Consumer United States
Primary
Concomitant
Injection Site Reaction 1/1/2008 Female 6/12/2008 United States
Primary
Concomitant
Underdose 2/1/2008 Male 198 lb 6/12/2008 Consumer United States
Primary
Concomitant
Procedural Complication 4/17/2008 Male 165 lb 6/12/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 5/8/2008 Female 205 lb 6/13/2008 United States
Primary
Concomitant
Accidental Exposure 5/30/2008 Female 220 lb 6/13/2008 Consumer United States
Primary
Concomitant
Malaise Other Serious 8/1/2008 Female 198 lb 9/4/2008 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 8/16/2008 Female 103 lb 9/5/2008 United States
Primary
Concomitant
Transverse Sinus Thrombosis Hospitalization 8/28/2008 Male 197 lb 9/3/2008 United States
Primary
Secondary
Concomitant
Swelling Hospitalization 1/1/2008 Female 282 lb 9/8/2008 Physician France
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 5/29/2008 Male 9/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection 4/1/2008 Female 159 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cells Urine Positive 4/1/2008 Female 160 lb 9/12/2008 Consumer United States
Primary
Concomitant
Joint Swelling 5/1/2008 Female 156 lb 9/12/2008 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/1/2008 1/23/2009 France
Primary
Concomitant
Interacting
Urosepsis Hospitalization 12/2/2008 Female 165 lb 3/2/2009 Australia
Primary
Concomitant
Deafness Other Serious 11/1/2008 4/6/2009 Other Health Professional France
Primary
Concomitant
Speech Disorder Other Serious 3/1/2009 Female 104 lb 4/8/2009 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/5/2001 64 Female 9/18/2009 Physician Spain
Primary
Concomitant
Herpes Zoster Hospitalization 7/22/2009 Female 154 lb 9/24/2009 Physician Austria
Primary
Concomitant
Suicidal Ideation Other Serious 10/5/2001 64 Female 9/29/2009 Physician Spain
Primary
Concomitant
Pancreatic Carcinoma Other Serious 9/16/2009 77 Male 155 lb 10/9/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Periorbital Cellulitis Hospitalization 6/11/2009 Female 192 lb 10/12/2009 Physician Canada
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 11/2/2009 Australia
Primary
Concomitant
Venous Thrombosis Other Serious 4/1/2007 Female 11/3/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2009 Female 11/10/2009 Pharmacist United Kingdom
Primary
Concomitant
Constipation Hospitalization 2/8/2008 Female 167 lb 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Fusion Surgery Other Serious Female 121 lb 11/17/2009 Brazil
Primary
Secondary
Concomitant
Constipation Hospitalization 2/8/2008 Female 167 lb 11/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 11/16/2009 Male 200 lb 11/25/2009 Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 2/20/2007 Female 132 lb 11/25/2009 Consumer United Kingdom
Primary
Concomitant
Haemarthrosis Hospitalization 9/8/2009 54 Female 146 lb 11/30/2009 Pharmacist United States
Primary
Concomitant
Wisdom Teeth Removal Other Serious 7/1/2009 Female 174 lb 12/10/2009 Brazil
Primary
Concomitant
Wound Haemorrhage 4/1/2009 12/10/2009 Consumer United States
Primary
Secondary
Concomitant
Depression Other Serious 8/20/2009 Male 176 lb 12/11/2009 Physician Denmark
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 12/10/2009 Consumer United States
Primary
Concomitant
Device Failure Other Serious 1/1/2008 Female 165 lb 12/18/2009 Brazil
Primary
Concomitant
Osteoarthritis Hospitalization 7/1/2009 75 Female 129 lb 12/21/2009 Other Health Professional Canada
Primary
Concomitant
Reversible Ischaemic Neurological Deficit Hospitalization 9/28/2009 Male 249 lb 12/22/2009 Germany
Primary
Concomitant
Surgery Hospitalization 10/21/2009 54 Female 12/22/2009 Other Health Professional Netherlands
Primary
Concomitant
Swelling Face Other Serious 1/1/2009 Female 110 lb 12/29/2009 Other Health Professional Canada
Primary
Concomitant
Nausea Hospitalization 5/21/2009 62 Female 181 lb 12/28/2009 Poland
Primary
Concomitant
Drug Ineffective Hospitalization 10/25/2009 58 Female 1/7/2010 Physician Italy
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/12/2009 Female 15 lb 12/30/2009 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 10/5/2001 64 Female 1/11/2010 Physician Spain
Primary
Concomitant
Vomiting Other Serious 12/28/2009 Male 1/12/2010 Consumer Canada
Primary
Secondary
Concomitant
Vertigo Other Serious 10/5/2001 64 Female 1/19/2010 Physician Spain
Primary
Concomitant
Muscular Weakness Other Serious 10/6/2009 Female 1/21/2010 Physician Germany
Primary
Concomitant
Visual Impairment Hospitalization 11/1/2009 Male 1/22/2010 Physician Germany
Primary
Concomitant
Thermal Burn Other Serious 1/1/2008 Female 1/25/2010 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious Female 121 lb 1/25/2010 Brazil
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 1/15/2008 46 Male 331 lb 1/25/2010 Germany
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Wisdom Teeth Removal Other Serious 7/1/2009 Female 154 lb 1/28/2010 Brazil
Primary
Concomitant
Libido Decreased Other Serious 8/20/2009 Male 176 lb 1/28/2010 Physician Denmark
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/26/2009 Male 187 lb 2/1/2010 Physician Germany
Primary
Concomitant
Drug Ineffective Hospitalization 10/25/2009 58 Female 2/12/2010 Physician Italy
Primary
Secondary
Concomitant
B-cell Lymphoma Other Serious 9/1/2009 Female 170 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 2/23/2010 Australia
Primary
Concomitant
Libido Decreased Other Serious 8/20/2009 Male 176 lb 3/3/2010 Physician Denmark
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 8/20/2009 Male 176 lb 3/11/2010 Physician Denmark
Primary
Secondary
Concomitant
Hip Fracture Hospitalization 6/29/2009 Male 159 lb 3/9/2010 Argentina
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Hip Fracture Hospitalization 6/29/2009 Male 159 lb 3/12/2010 Physician Argentina
Primary
Concomitant
Leukopenia Hospitalization 3/3/2010 68 Female 117 lb 3/18/2010 Physician Germany
Primary
Concomitant
Wound Drainage Other Serious 7/1/2009 Female 130 lb 3/19/2010 Brazil
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2008 Female 220 lb 3/19/2010 Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 9/1/2009 Female 132 lb 3/22/2010 Brazil
Primary
Concomitant
Neuropathy Peripheral Hospitalization 14 Female 3/23/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Leukopenia Hospitalization 3/3/2010 68 Female 117 lb 3/24/2010 Other Health Professional Germany
Primary
Concomitant
Wound Drainage Other Serious 7/1/2009 Female 130 lb 3/24/2010 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 3/16/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/24/2009 Female 181 lb 3/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 10/25/2009 58 Female 3/30/2010 Physician Italy
Primary
Secondary
Concomitant
Fall Hospitalization 2/26/2010 64 Female 160 lb 4/6/2010 Consumer Canada
Primary
Concomitant
Renal Failure Life Threatening 11/1/2009 38 Female 4/9/2010 Other Health Professional Switzerland
Primary
Secondary
Syncope Other Serious 1/1/2008 47 Female 4/16/2010 Consumer Brazil
Primary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 4/19/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Life Threatening 11/1/2009 38 Female 4/20/2010 Other Health Professional Switzerland
Primary
Secondary
Tachypnoea Other Serious 8/30/2007 59 Female 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/1/2010 31 Female 143 lb 4/22/2010 Brazil
Primary
Concomitant
Vision Blurred Other Serious Male 144 lb 4/23/2010 Other Health Professional Canada
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 8/1/2008 68 Female 121 lb 4/29/2010 Brazil
Primary
Secondary
Concomitant
Sjogren's Syndrome Other Serious 1/1/2005 68 Female 200 lb 5/12/2010 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 16 Female 5/21/2010
Primary
Secondary
Urinary Tract Infection Other Serious 6/25/2008 50 Female 115 lb 5/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 27 Female 115 lb 5/26/2010 Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 27 Female 115 lb 5/28/2010 Brazil
Primary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 5/29/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/25/2008 50 Female 115 lb 6/3/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia 2/1/2010 52 Male 230 lb 5/11/2010 Consumer United States
Primary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 6/3/2010 Physician Germany
Primary
Secondary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 6/10/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 1/1/2009 61 Female 6/15/2010 Physician Germany
Primary
Secondary
Concomitant
Drug Interaction Other Serious 6/22/2010 Physician France
Primary
Interacting
Drug Interaction Other Serious 6/22/2010 Physician France
Primary
Interacting
Pneumonia Legionella Other Serious 1/14/2005 63 Male 183 lb 6/28/2010 Physician Germany
Primary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 6/18/2010 70 Male 115 lb 7/6/2010 Consumer United States
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 6/18/2010 69 Female 218 lb 7/9/2010 Physician Canada
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 6/14/2010 69 Female 132 lb 7/12/2010 Consumer Canada
Primary
Concomitant
Myocardial Infarction Life Threatening 10/7/2009 53 Male 181 lb 7/14/2010 Physician Netherlands
Primary
Concomitant
C-reactive Protein Increased Other Serious 6/14/2010 47 Female 265 lb 7/16/2010 Physician Egypt
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 63 Male 7/16/2010 Physician Australia
Primary
Concomitant
Skin Laceration 5/26/2010 7/7/2010 Consumer United States
Primary
Concomitant
Lobar Pneumonia Hospitalization 6/9/2010 77 Female 146 lb 7/16/2010 Other Health Professional Germany
Primary
Concomitant
Melaena Other Serious 7/1/2010 Female 165 lb 7/23/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious Female 7/27/2010 Consumer Canada
Primary
Concomitant
Gait Disturbance Other Serious 6/1/2010 41 Female 126 lb 7/28/2010 Physician Brazil
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/1/2010 70 Female 127 lb 7/28/2010 Physician Canada
Primary
Concomitant
Gastritis Erosive Hospitalization 7/15/2010 59 Female 251 lb 7/30/2010 Physician Switzerland
Primary
Secondary
Concomitant
Mediastinal Mass Other Serious 7/20/2010 64 Male 212 lb 8/2/2010 Physician Canada
Primary
Concomitant
Nausea Other Serious 6/1/2010 67 Female 8/2/2010 Physician Austria
Primary
Concomitant
Interacting
Gait Disturbance Other Serious 6/1/2010 41 Female 126 lb 8/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Menorrhagia Other Serious 11/25/2008 40 Female 126 lb 8/5/2010 Physician Brazil
Primary
Secondary
Concomitant
Rheumatoid Factor Increased Other Serious 5/1/2010 69 Female 143 lb 8/6/2010 Consumer Brazil
Primary
Secondary
Concomitant
Strabismus Other Serious 7/1/2010 56 Female 150 lb 8/6/2010 Consumer Canada
Primary
Concomitant
Spinal Fracture Other Serious 6/14/2010 69 Female 132 lb 8/6/2010 Physician Canada
Primary
Concomitant
Hepatic Steatosis Hospitalization 7/15/2010 59 Female 218 lb 8/9/2010 Physician Switzerland
Primary
Secondary
Concomitant
Menorrhagia Other Serious 6/1/2010 41 Female 126 lb 8/11/2010 Physician Brazil
Primary
Secondary
Concomitant
Tuberculin Test Positive Other Serious 11/1/2009 42 Male 220 lb 8/18/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 63 Male 8/18/2010 Physician Australia
Primary
Concomitant
Strabismus Other Serious 7/1/2010 56 Female 150 lb 8/18/2010 Physician Canada
Primary
Concomitant
Myocardial Infarction Other Serious 8/4/2010 59 Male 8/20/2010 Other Health Professional Canada
Primary
Concomitant

Drug Data