Methotrexate combined with Selbex

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rheumatoid Arthritis Other Serious 12/25/2003 56 Female 101 lb 1/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/5/2005 58 Male 1/20/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/17/2005 Female 101 lb 2/17/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/2/2005 Female 131 lb 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/17/2005 Female 101 lb 2/28/2006 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 3/15/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 3/11/2005 Female 110 lb 3/17/2006 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/1/2005 76 Male 3/18/2006 Pharmacist Japan
Primary
Concomitant
Oedema Other Serious 2/21/2005 Male 137 lb 3/21/2006 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 5/24/2006 Female 115 lb 7/26/2006 Physician Japan
Primary
Concomitant
Infusion Related Reaction Other Serious 5/24/2006 Female 115 lb 8/16/2006 Physician Japan
Primary
Concomitant
Flushing Hospitalization 10/25/2005 Female 99 lb 9/8/2006 Physician Japan
Primary
Concomitant
Lymphoma Hospitalization 2/14/2005 Female 99 lb 9/11/2006 Physician Japan
Primary
Concomitant
Peritoneal Tuberculosis Other Serious 12/26/2003 Female 9/14/2006 Physician Japan
Primary
Concomitant
Neck Pain Hospitalization 8/19/2006 Male 11/29/2006 Physician Japan
Primary
Concomitant
Atypical Mycobacterial Infection Hospitalization 3/22/2006 Female 117 lb 12/6/2006 Physician Japan
Primary
Concomitant
Mediastinal Abscess Hospitalization 9/27/2006 Male 12/12/2006 Physician Japan
Primary
Concomitant
Scleritis Other Serious 11/10/2006 Female 1/19/2007 Physician Japan
Primary
Concomitant
Iritis Life Threatening 11/7/2006 Female 95 lb 1/25/2007 Physician Japan
Primary
Concomitant
Lymphoma Other Serious 9/14/2006 Female 95 lb 2/14/2007 Physician Japan
Primary
Concomitant
Atypical Mycobacterial Infection Hospitalization 3/22/2006 Female 117 lb 2/20/2007 Physician Japan
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 11/24/2006 Female 108 lb 4/3/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 3/4/2007 Female 146 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 3/4/2007 Female 146 lb 4/30/2007 Physician Japan
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 3/4/2007 Female 146 lb 5/1/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/4/2007 Female 146 lb 6/11/2007 Physician Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 9/2/2003 Male 159 lb 6/12/2007 Physician Japan
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 10/17/2003 Female 97 lb 6/15/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/30/2004 Female 84 lb 6/17/2007 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 6/4/2006 Female 79 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/14/2005 61 Female 115 lb 9/13/2007 Physician Japan
Primary
Concomitant
Oedema Other Serious 2/21/2005 Male 137 lb 10/18/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 9/24/2007 44 Female 108 lb 11/5/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Eczema Other Serious 7/29/2007 Male 159 lb 12/7/2007 Physician Japan
Primary
Secondary
Concomitant
Peritoneal Perforation Hospitalization 7/29/2007 Male 159 lb 12/21/2007 Physician Japan
Primary
Secondary
Concomitant
Petechiae Hospitalization 8/9/2007 Male 159 lb 1/7/2008 Physician Japan
Primary
Secondary
Concomitant
Osteitis Other Serious 1/8/2008 Female 1/25/2008 Physician Japan
Primary
Concomitant
Oral Pustule 1/8/2008 Female 1/29/2008 Physician Japan
Primary
Concomitant
Petechiae Hospitalization 1/1/2007 Male 159 lb 2/15/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Petechiae Hospitalization 3/1/2007 Male 159 lb 3/4/2008 Physician Japan
Primary
Secondary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 4/14/2005 Female 99 lb 3/7/2008 Physician Japan
Primary
Concomitant
Peritonitis Hospitalization 3/1/2007 Male 159 lb 3/21/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/17/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/22/2008 Physician Japan
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Atypical Mycobacterial Infection Hospitalization 3/22/2006 Female 117 lb 5/23/2008 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/11/2007 Female 88 lb 5/30/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 7/15/2008 Physician Japan
Primary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 3/4/2007 Female 146 lb 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 8/16/2008 51 Male 97 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/19/2006 9 Male 51 lb 7/10/2009 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 7/10/2009 Female 169 lb 7/28/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 7/10/2009 Female 169 lb 8/3/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Sepsis Other Serious 8/8/2008 51 Male 97 lb 9/3/2009 Physician Japan
Primary
Secondary
Concomitant
Synovial Cyst Life Threatening 8/28/2009 Male 128 lb 9/24/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 8/8/2008 51 Male 97 lb 10/14/2009 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 2/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 9/5/2008 Female 2/23/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 5/14/2009 Female 95 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 3/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 3/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 106 lb 5/6/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2007 9 Male 51 lb 5/21/2010 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Life Threatening 7/1/2009 61 Female 137 lb 6/8/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/2/2009 69 Female 122 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 10/1/2009 61 Female 88 lb 8/9/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 8/22/2008 73 Female 90 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 3/23/2010 74 Female 9/24/2010 Physician Japan
Primary
Concomitant
Pneumonia 10/30/2009 69 Female 126 lb 10/1/2010 Physician Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 10/19/2010 80 Female 12/6/2010 Physician Japan
Primary
Concomitant
Pulmonary Mass Hospitalization 9/1/2010 12/13/2010 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 9/15/2001 32 Female 88 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 7/13/2010 61 Female 143 lb 12/28/2010 Physician Japan
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 10/19/2010 80 Female 130 lb 12/29/2010 Physician Japan
Primary
Concomitant
Circulatory Collapse Life Threatening 9/15/2001 32 Female 88 lb 1/12/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 1/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Alopecia Hospitalization 10/21/2010 73 Female 2/6/2011 Consumer Japan
Primary
Secondary
Concomitant
Gastritis Other Serious 7/13/2010 61 Female 143 lb 2/14/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Other Serious 10/1/2009 61 Female 88 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 1/1/2009 10 Male 4/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Cancer Hospitalization 2/21/2011 60 Female 101 lb 4/8/2011 Physician Japan
Primary
Secondary
Concomitant
Reye's Syndrome Life Threatening 9/15/2001 32 Female 88 lb 4/15/2011 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 7/13/2010 61 Female 143 lb 4/25/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 7/13/2010 61 Female 143 lb 4/25/2011 Physician Japan
Primary
Concomitant
Diverticulitis Other Serious 9/28/2010 40 Male 176 lb 5/2/2011 Physician Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 5/28/2010 54 Female 104 lb 5/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Headache Death 6/12/2009 70 Male 162 lb 5/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Malignant Melanoma Hospitalization 2/21/2011 60 Female 101 lb 6/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Malignant Melanoma Hospitalization 2/21/2011 60 Female 101 lb 6/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Eczema Death 6/12/2009 70 Male 162 lb 6/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Macular Hole Hospitalization 64 Male 6/22/2011 Consumer Japan
Primary
Secondary
Concomitant
Erythema Hospitalization 9/1/2010 39 Female 117 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Malignant Melanoma Hospitalization 2/21/2011 60 Female 101 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 9/1/2010 39 Female 117 lb 7/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Aplastic Anaemia Hospitalization 1/21/2011 60 Female 99 lb 7/14/2011 Consumer Japan
Primary
Secondary
Concomitant
Arthralgia Hospitalization 9/1/2010 39 Female 117 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 3/23/2010 74 Female 7/27/2011 Physician Japan
Primary
Concomitant
Lymphoma Other Serious 8/1/2010 81 Female 101 lb 7/11/2011 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 3/23/2010 74 Female 8/1/2011 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/6/2011 72 Female 99 lb 8/11/2011 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/6/2011 72 Female 99 lb 8/16/2011 Physician Japan
Primary
Concomitant
Atypical Mycobacterial Infection Other Serious 8/1/2010 54 Female 99 lb 8/18/2011 Physician Japan
Primary
Concomitant
Diverticulitis Other Serious 9/28/2010 40 Male 176 lb 8/23/2011 Physician Japan
Primary
Concomitant
Macular Hole Hospitalization 64 Male 8/25/2011 Consumer Japan
Primary
Secondary
Concomitant
Colon Cancer Life Threatening 2/1/2011 80 Male 139 lb 9/4/2011 Physician Japan
Primary
Concomitant
Gastric Ulcer Disability 10/21/2010 73 Female 9/13/2011 Consumer Japan
Primary
Secondary
Concomitant
Gastric Ulcer Disability 10/21/2010 73 Female 9/19/2011 Consumer Japan
Primary
Secondary
Concomitant
Nasopharyngitis Hospitalization 4/2/2010 29 Female 9/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 3/23/2010 74 Female 9/26/2011 Japan
Primary
Concomitant
Cerebral Haemorrhage Other Serious 12/13/2010 50 Female 9/30/2011 Japan
Primary
Concomitant
Aplastic Anaemia Hospitalization 1/21/2011 60 Female 99 lb 10/27/2011 Physician Japan
Primary
Secondary
Concomitant
Henoch-schonlein Purpura Hospitalization 12/1/2010 68 Female 148 lb 11/4/2011 Physician Japan
Primary
Concomitant
Salivary Gland Calculus Other Serious 7/20/2011 75 Male 11/8/2011 Consumer Japan
Primary
Secondary
Concomitant
Pneumothorax Death 9/6/2011 71 Female 95 lb 11/10/2011 Physician Japan
Primary
Secondary
Concomitant
Salivary Gland Calculus Other Serious 7/20/2011 75 Male 11/14/2011 Consumer Japan
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 11/28/2010 68 Female 148 lb 11/29/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 9/1/2011 71 Female 95 lb 12/9/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 9/12/2011 73 Female 93 lb 12/12/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/6/2011 72 Female 99 lb 12/19/2011 Consumer Japan
Primary
Concomitant
Macular Hole Hospitalization 5/1/2011 64 Male 12/28/2011 Consumer Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 12/13/2010 50 Female 12/29/2011 Japan
Primary
Concomitant
Pulmonary Tuberculosis Life Threatening 9/1/2011 73 Female 93 lb 1/10/2012 Physician Japan
Primary
Secondary
Concomitant
Macular Hole Hospitalization 5/1/2011 64 Male 1/16/2012 Consumer Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 4/2/2010 29 Female 1/26/2012 Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 11/18/2011 82 Female 77 lb 2/8/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 1/8/2012 83 Male 128 lb 2/23/2012 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Life Threatening 11/28/2011 61 Female 139 lb 2/24/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 1/8/2012 83 Male 128 lb 2/27/2012 Physician Japan
Primary
Secondary
Concomitant
Salivary Gland Calculus Other Serious 7/20/2011 75 Male 2/28/2012 Consumer Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/1/2011 81 Female 77 lb 3/1/2012 Physician Japan
Primary
Secondary
Concomitant
Colon Cancer Life Threatening 2/1/2011 80 Male 139 lb 3/2/2012 Physician Japan
Primary
Concomitant
Acute Respiratory Failure Death 1/8/2012 83 Male 128 lb 3/6/2012 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Life Threatening 9/1/2011 73 Female 93 lb 3/12/2012 Physician Japan
Primary
Secondary
Concomitant
Salivary Gland Calculus Other Serious 7/20/2011 75 Male 4/2/2012 Physician Japan
Primary
Secondary
Concomitant
Necrotising Oesophagitis Other Serious 1/1/2011 81 Female 77 lb 4/6/2012 Physician Japan
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 4/4/2012 39 Female 157 lb 4/16/2012 Physician Japan
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 4/4/2012 39 Female 157 lb 4/20/2012 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 4/28/2009 75 Female 4/27/2012 Japan
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 11/22/2010 82 Female 75 lb 5/29/2012 Japan
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 4/28/2009 75 Female 6/6/2012 Japan
Primary
Secondary
Concomitant
Thymoma Other Serious 4/18/2012 82 Female 88 lb 6/12/2012 Physician Japan
Primary
Concomitant
Thymoma Life Threatening 4/18/2012 82 Female 88 lb 6/14/2012 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Life Threatening 9/1/2011 73 Female 93 lb 7/2/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 12/10/2011 61 Female 99 lb 7/11/2012 Physician Japan
Primary
Concomitant
Arthralgia Other Serious 11/18/2010 82 Female 75 lb 7/17/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data