Methotrexate combined with Roactemra

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Septic Shock Death 3/1/2010 46 Female 143 lb 4/6/2010 Consumer Belgium
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/1/2010 66 Male 203 lb 4/14/2010 Other Health Professional Belgium
Primary
Concomitant
Septic Shock Death 3/1/2010 46 Female 143 lb 4/15/2010 Consumer Belgium
Primary
Concomitant
Pneumonia Death 3/23/2010 53 Female 4/15/2010 Physician Mexico
Primary
Concomitant
Post Herpetic Neuralgia Other Serious 1/10/2010 71 Female 134 lb 4/17/2010 Physician France
Primary
Concomitant
Interstitial Lung Disease Hospitalization 12/31/2009 66 Female 4/19/2010 Physician Sweden
Primary
Secondary
Transient Ischaemic Attack Hospitalization 11/16/2009 65 Female 4/26/2010 Physician Denmark
Primary
Concomitant
Vasculitis Hospitalization 10/17/2009 59 Female 4/29/2010 Consumer Ireland
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 2/9/2010 70 Female 5/4/2010 Physician Denmark
Primary
Concomitant
Herpes Zoster Other Serious 9/19/2009 67 Female 154 lb 5/11/2010 Other Health Professional Denmark
Primary
Concomitant
Septic Shock Life Threatening 5/2/2010 39 Female 5/21/2010 Consumer Spain
Primary
Concomitant
Facial Palsy Other Serious 2/10/2010 43 Female 121 lb 5/24/2010 Physician Belgium
Primary
Concomitant
Neutropenia Hospitalization 5/1/2010 70 Male 5/25/2010 Physician France
Primary
Secondary
Post Herpetic Neuralgia Other Serious 1/10/2010 71 Female 134 lb 5/26/2010 Physician France
Primary
Concomitant
Neutropenia Hospitalization 5/1/2010 70 Male 5/27/2010 Physician United Kingdom
Primary
Secondary
Paraesthesia Hospitalization 4/1/2010 29 Female 6/1/2010 Physician Sweden
Primary
Concomitant
Otitis Media Other Serious 9/17/2009 13 Male 52 lb 6/9/2010 Physician Spain
Primary
Concomitant
Otitis Media Other Serious 9/17/2009 13 Female 52 lb 6/15/2010 Physician Spain
Primary
Concomitant
Septic Shock Life Threatening 5/2/2010 39 Female 134 lb 6/16/2010 Consumer Spain
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 5/1/2010 58 Female 6/16/2010 Consumer Belgium
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 5/1/2010 58 Female 150 lb 6/22/2010 Consumer Belgium
Primary
Concomitant
Subcutaneous Haematoma Other Serious 1/1/2010 80 Female 132 lb 7/9/2010 Consumer Belgium
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 2/9/2010 70 Female 119 lb 7/16/2010 Physician Denmark
Primary
Concomitant
Tachycardia Other Serious 7/7/2010 34 Female 7/19/2010 Other Health Professional Ireland
Primary
Concomitant
Tinnitus Other Serious Female 154 lb 7/27/2010 Pharmacist Ireland
Primary
Concomitant
Peritonitis Life Threatening 5/19/2010 50 Female 7/27/2010 Physician France
Primary
Secondary
Concomitant
Tachycardia Other Serious 7/7/2010 34 Female 7/30/2010 Other Health Professional Ireland
Primary
Concomitant
Malaise Hospitalization 6/26/2010 58 Female 8/4/2010 Physician France
Primary
Concomitant
Anaemia Macrocytic Hospitalization 1/1/2010 70 Male 134 lb 8/5/2010 Physician France
Primary
Concomitant
Tachycardia Other Serious 7/7/2010 34 Female 168 lb 8/10/2010 Other Health Professional Ireland
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 11/16/2009 65 Female 128 lb 8/11/2010 Physician Denmark
Primary
Concomitant
Tachycardia Other Serious 7/7/2010 34 Female 168 lb 8/16/2010 Other Health Professional Ireland
Primary
Concomitant
Septic Shock Life Threatening 8/5/2010 81 Female 128 lb 8/18/2010 Consumer Mexico
Primary
Concomitant
Death Death 7/6/2010 71 Female 8/23/2010 Other Health Professional Spain
Primary
Concomitant
Septic Shock Life Threatening 8/5/2010 81 Female 128 lb 8/24/2010 Consumer Mexico
Primary
Concomitant
Pulmonary Oedema Death 8/12/2010 63 Female 143 lb 8/25/2010 Consumer Hungary
Primary
Concomitant
Pericarditis Hospitalization 5/5/2010 70 Male 8/25/2010 Physician France
Primary
Secondary
Concomitant
Tinnitus Other Serious Female 154 lb 8/26/2010 Pharmacist Ireland
Primary
Concomitant
Tachypnoea Other Serious 7/1/2010 2 Female 8/26/2010 Other Health Professional Czech Republic
Primary
Concomitant
Viith Nerve Paralysis Other Serious 2/10/2010 43 Female 121 lb 8/27/2010 Physician Belgium
Primary
Concomitant
Cytolytic Hepatitis Other Serious 12/24/2009 20 Female 8/27/2010 Pharmacist France
Primary
Secondary
Concomitant
Sepsis Death 7/13/2010 60 Female 9/2/2010 Physician Sweden
Primary
Concomitant
Urinary Tract Infection Other Serious 7/27/2010 Female 249 lb 9/9/2010 Consumer Denmark
Primary
Concomitant
Tinnitus 7/15/2010 43 Female 152 lb 9/15/2010 Pharmacist Ireland
Primary
Concomitant
Thrombocytopenia Hospitalization 7/13/2010 60 Female 9/20/2010 Physician Sweden
Primary
Concomitant
Malignant Melanoma Other Serious 5/1/2010 58 Female 150 lb 9/22/2010 Consumer Belgium
Primary
Concomitant
Malignant Melanoma Other Serious 5/1/2010 58 Female 150 lb 9/28/2010 Consumer Belgium
Primary
Concomitant
Vasculitis Cerebral Hospitalization Female 9/30/2010 Physician Germany
Primary
Concomitant
Nausea Hospitalization 9/10/2010 50 Female 9/30/2010 Physician Germany
Primary
Concomitant
Disease Recurrence Other Serious 4/19/2010 50 Female 10/14/2010 Physician France
Primary
Concomitant
Skin Infection Other Serious 8/13/2010 13 Female 101 lb 10/15/2010 Consumer Denmark
Primary
Concomitant
Urosepsis Life Threatening 7/1/2010 55 Male 10/26/2010 Consumer Czech Republic
Primary
Concomitant
Vasculitis Cerebral Hospitalization 9/5/2010 55 Female 287 lb 10/29/2010 Physician Germany
Primary
Concomitant
Septic Shock Life Threatening 4/14/2010 47 Female 198 lb 11/1/2010 Physician France
Primary
Concomitant
Skin Infection Other Serious 8/13/2010 13 Female 101 lb 11/3/2010 Consumer Denmark
Primary
Concomitant
Sepsis Other Serious 6/1/2010 55 Male 11/9/2010 Consumer Czech Republic
Primary
Concomitant
Amenorrhoea Other Serious 11/1/2010 45 Female 11/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 9/27/2010 20 Male 86 lb 11/24/2010 Consumer Belgium
Primary
Concomitant
Arthritis Other Serious 7/31/2010 56 Male 132 lb 11/29/2010 Consumer Spain
Primary
Concomitant
Septic Arthritis Streptococcal Hospitalization 7/30/2010 75 Female 154 lb 11/30/2010 Consumer Denmark
Primary
Secondary
Concomitant
Intraocular Pressure Increased Disability 11/4/2010 50 Female 161 lb 12/8/2010 Consumer Spain
Primary
Concomitant
Sensorimotor Disorder Hospitalization 4/22/2010 41 Female 12/14/2010 Other Health Professional Italy
Primary
Concomitant
Septic Arthritis Streptococcal Hospitalization 7/30/2010 75 Female 154 lb 12/22/2010 Consumer Denmark
Primary
Secondary
Concomitant
Sensorimotor Disorder Hospitalization 4/22/2010 41 Female 12/27/2010 Other Health Professional Italy
Primary
Concomitant
Laparotomy Death 11/20/2010 73 Female 12/30/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 1/10/2010 71 Female 134 lb 1/3/2011 Consumer France
Primary
Concomitant
Laparotomy Death 11/20/2010 73 Female 1/10/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Pleural Fibrosis Hospitalization 11/25/2010 71 Male 1/14/2011 Physician Sweden
Primary
Concomitant
Abdominal Abscess Hospitalization 11/20/2010 73 Female 1/18/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 3/27/2010 62 Male 1/18/2011 Other Health Professional France
Primary
Secondary
Leukopenia Other Serious 12/1/2010 68 Male 1/19/2011 Physician France
Primary
Secondary
Concomitant
Abdominal Abscess Hospitalization 12/1/2010 30 Female 1/27/2011 Consumer Denmark
Primary
Concomitant
Leukopenia Other Serious 12/1/2010 68 Male 1/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Psoriasis Other Serious 9/22/2010 49 Female 168 lb 2/2/2011 Physician United Kingdom
Primary
Concomitant
Demyelinating Polyneuropathy Hospitalization 10/20/2010 73 Female 110 lb 2/4/2011 Consumer Greenland
Primary
Concomitant
Hypertension Hospitalization 11/1/2010 Female 2/4/2011 Consumer Netherlands
Primary
Concomitant
Drug Ineffective Hospitalization 11/9/2010 37 Female 2/11/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 12/6/2010 32 Female 2/15/2011 Other Health Professional France
Primary
Secondary
Abdominal Abscess Hospitalization 11/25/2010 31 Female 108 lb 2/17/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Demyelinating Polyneuropathy Hospitalization 10/20/2010 73 Female 110 lb 2/21/2011 Physician Greenland
Primary
Concomitant
Sudden Death Death 1/24/2011 54 Female 247 lb 2/23/2011 Consumer France
Primary
Concomitant
Ligament Rupture Disability 1/9/2011 45 Female 2/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 6 57 lb 3/1/2011 Consumer Greece
Primary
Concomitant
Blindness Disability 1/20/2011 59 Female 3/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Venous Thrombosis Limb Other Serious 12/24/2010 Male 3/8/2011 Other Health Professional Sweden
Primary
Secondary
Abdominal Pain Hospitalization 11/9/2010 37 Female 3/9/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/27/2010 62 Male 3/10/2011 Physician France
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 1/1/2011 Female 3/16/2011 Consumer France
Primary
Concomitant
Eye Pain Hospitalization Female 174 lb 3/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Eye Pain Disability 1/20/2011 59 Female 174 lb 3/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Calcitonin Increased Other Serious 12/1/2010 68 Female 126 lb 3/24/2011 Consumer Belgium
Primary
Concomitant
Circulatory Collapse Other Serious 12/10/2010 31 Male 172 lb 3/24/2011 Physician Germany
Primary
Concomitant
Inflammation Death 1/1/2011 65 Female 4/7/2011 Physician Spain
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/1/2011 70 Female 143 lb 4/7/2011 Physician Netherlands
Primary
Concomitant
Cytolytic Hepatitis Other Serious 12/6/2010 32 Female 4/8/2011 Other Health Professional France
Primary
Secondary
Vasculitis Hospitalization 2/1/2011 70 Female 143 lb 4/11/2011 Physician Netherlands
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 3/15/2009 69 Male 134 lb 4/12/2011 Physician France
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/14/2011 65 Male 152 lb 4/18/2011 Consumer Spain
Primary
Concomitant
Subcutaneous Nodule Hospitalization 12/1/2010 61 Male 165 lb 4/22/2011 Other Health Professional France
Primary
Secondary
Concomitant
Erysipelas Hospitalization 3/4/2011 56 Female 187 lb 4/28/2011 Consumer France
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 6/30/2010 72 Male 135 lb 8/20/2012 Physician United States
Primary
Concomitant
Septic Shock Death 9/16/2011 51 Female 106 lb 8/20/2012 Physician Brazil
Primary
Concomitant
Shock Life Threatening 10/15/2011 77 Female 125 lb 8/20/2012 Physician Spain
Primary
Secondary
Concomitant
Pyrexia Death 7/1/2012 47 Female 132 lb 8/20/2012 Physician Colombia
Primary
Secondary
Concomitant
Metastatic Bronchial Carcinoma Death 11/1/2011 57 Male 8/22/2012 Physician Germany
Primary
Secondary
Pelvic Pain Death 10/15/2011 77 Female 125 lb 8/23/2012 Physician Spain
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/16/2012 75 Female 179 lb 8/23/2012 Consumer Canada
Primary
Concomitant
Productive Cough Other Serious 7/1/2012 49 Female 175 lb 8/23/2012 Consumer Canada
Primary
Concomitant
Aspartate Aminotransferase Increased Life Threatening 12/9/2009 47 Male 194 lb 8/23/2012 Physician Germany
Primary
Concomitant
Tachycardia Other Serious 6/12/2012 26 Male 8/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Aortic Dissection Hospitalization 1/5/2011 61 Female 8/24/2012 Physician Japan
Primary
Concomitant
Pneumonia Pneumococcal Life Threatening 2009 Female 123 lb 9/7/2012 Physician Jp
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/2/2010 40 Female 143 lb 9/10/2012 Physician Es
Primary
Concomitant
Organising Pneumonia Hospitalization 6/23/2010 66 Female 90 lb 9/6/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Life Threatening Female 148 lb 9/14/2012 Physician Fr
Primary
Concomitant
Myelocytosis Other Serious 4/5/2011 45 Female 9/24/2012 Physician Fr
Primary
Concomitant
Myocardial Infarction Life Threatening 1/31/2012 54 Male 220 lb 10/3/2012 Physician No
Primary
Concomitant
Rheumatoid Arthritis Death 1/16/2012 76 Female 179 lb 10/11/2012 Physician Ca
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/7/2012 65 Female 163 lb 10/1/2012 Physician Fr
Primary
Concomitant
Vasculitis Other Serious Female 10/31/2012 Physician Fi
Primary
Concomitant
Thrombocytopenic Purpura Hospitalization 7/20/2011 48 Female 185 lb 10/10/2012 Physician Fr
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 5/2012 63 Female 1/11/2013 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Synovial Rupture Hospitalization 5/2/2012 68 Female 9/19/2012 Physician Es
Primary
Secondary
Concomitant
Vasculitis Necrotising Other Serious 5/3/2012 79 Female 11/22/2012 Physician Es
Primary
Concomitant
Pneumonia Death 5/25/2012 82 Female 132 lb 9/7/2012 Physician Ar
Primary
Concomitant
Sepsis Other Serious 3/5/2012 64 Male 12/20/2012 Other Health Professional Gb
Primary
Concomitant
Paraesthesia Hospitalization 6/12/2012 50 Male 9/27/2012 Physician Dk
Primary
Secondary
Concomitant
Polydactyly Congenital Anomaly 2/23/2012 Male 9/22/2012 Physician Dk
Primary
Secondary
Concomitant
Skin Cancer Metastatic Hospitalization 12/4/2009 52 Female 8/29/2012 Physician Jp
Primary
Concomitant
Thrombosis Other Serious 7/30/2012 28 Male 9/19/2012 Other Health Professional Gb
Primary
Concomitant
Tonsillitis Other Serious 8/15/2012 12 Male 75 lb 9/26/2012 Other Health Professional Ie
Primary
Concomitant
Diverticulum Intestinal Haemorrhagic Other Serious 8/30/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Encephalitis Herpes Hospitalization 6/18/2012 62 Male 201 lb 9/26/2012 Other Health Professional It
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/5/2012 50 Female 9/5/2012 Other Health Professional Au
Primary
Concomitant
Myocardial Infarction Hospitalization 8/11/2012 54 Female 170 lb 9/7/2012 Physician Ca
Primary
Concomitant
Death Death Female 291 lb 9/4/2012 Other Health Professional Ca
Primary
Concomitant
Sinusitis Other Serious 9/2011 59 Female 161 lb 9/7/2012 Physician Fr
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2012 Female 193 lb 9/12/2012 Consumer Ca
Primary
Concomitant
Ligament Sprain Other Serious 5/29/2012 73 Male 195 lb 9/13/2012 Consumer Ca
Primary
Concomitant
Vitamin D Deficiency Hospitalization 7/28/2010 30 Female 128 lb 9/13/2012 Physician Fr
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 9/27/2011 58 Female 10/12/2012 Physician Jp
Primary
Secondary
Concomitant
Neutropenia Other Serious 8/30/2012 67 Female 169 lb 10/11/2012 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/2012 Female 104 lb 9/22/2012 Other Health Professional Ca
Primary
Concomitant
Vertigo Other Serious 8/11/2012 40 Female 9/22/2012 Other Health Professional Au
Primary
Concomitant
Weight Decreased Hospitalization 8/2011 38 Female 141 lb 9/25/2012 Physician Fr
Primary
Secondary
Concomitant
Pleurisy Hospitalization 1/30/2012 Female 9/26/2012 Physician De
Primary
Secondary
Concomitant
Malaise Other Serious 6/2011 63 Female 181 lb 9/27/2012 Physician Fr
Primary
Concomitant
Vein Disorder Hospitalization 6/21/2012 69 Female 165 lb 10/1/2012 Consumer Gb
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 3/10/2012 65 Female 12/3/2012 Physician Dk
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/1/2011 43 Female 153 lb 10/5/2012 Physician Br
Primary
Secondary
Concomitant

Drug Data