Clonidine combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Noncompliance Other Serious 1/1/2005 44 Female 1/4/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2003 37 Female 6/28/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2003 37 Female 6/22/2006 Physician United States
Primary
Concomitant
Convulsion Hospitalization 6/14/2006 Male 150 lb 7/19/2006 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Other Serious 6/7/2001 68 Female 7/5/2006 United States
Primary
Concomitant
Syncope Hospitalization 1/1/2006 Female 156 lb 8/18/2006 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 5/13/2004 Female 100 lb 9/6/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 38 Female 10/16/2006 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Hospitalization 11/21/2005 32 Female 11/17/2006 Other Health Professional Sweden
Primary
Concomitant
Myocardial Infarction Death 9/21/2006 Female 130 lb 11/20/2006 Physician Canada
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Vertigo Hospitalization 1/24/2007 41 Female 231 lb 1/26/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Oesophagogastric Fundoplasty Hospitalization 1/12/2007 Female 2/23/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Temporal Lobe Epilepsy Hospitalization 8/30/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Death Death 1/1/2004 73 Unknown 3/22/2007 Pharmacist United States
Primary
Secondary
Somnolence 3/1/2007 Female 300 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 71 Female 9/20/2007 Physician Canada
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 8 Male 10/17/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 150 lb 11/15/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/14/2007 Consumer United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/1/2007 Female 150 lb 11/29/2007 Physician United States
Primary
Concomitant
Local Swelling Other Serious 8/1/2007 Female 12/14/2007 Physician United States
Primary
Concomitant
Polyp Other Serious 8 Male 1/11/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Migraine Other Serious 10/16/2007 Female 146 lb 2/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Iucd Complication 1/1/2007 32 Female 154 lb 2/13/2008 Consumer United States
Primary
Concomitant
Rheumatoid Nodule Other Serious 8/2/2007 Female 141 lb 2/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatic Carcinoma Metastatic Other Serious 2/14/2008 Male 200 lb 3/11/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Irritation 1/1/2005 Female 225 lb 3/15/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2008 Female 135 lb 3/15/2008 Consumer United States
Primary
Concomitant
Asthma Other Serious 12/6/2007 Female 160 lb 3/26/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 9/1/2007 Male 220 lb 5/7/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/1/2007 Male 220 lb 5/12/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Metastatic Other Serious 2/14/2008 Male 200 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis 12/1/2007 61 Female 154 lb 5/19/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2007 Male 220 lb 5/19/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 59 Female 5/28/2008 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis 12/1/2007 61 Female 154 lb 5/29/2008 Other Health Professional United States
Primary
Concomitant
Mania 2/1/2008 Male 6/12/2008 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 2/24/2008 79 Female 168 lb 5/21/2008 Pharmacist United States
Primary
Concomitant
Sensory Disturbance Other Serious 5/1/2008 Female 6/20/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/25/2008 Female 8/7/2008 Other Health Professional Italy
Primary
Concomitant
Myocardial Infarction Hospitalization 6/25/2008 Female 231 lb 9/10/2008 Other Health Professional Italy
Primary
Concomitant
Psoriasis 10/2/2006 Female 115 lb 9/12/2008 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 7/1/2008 Female 214 lb 9/12/2008 United States
Primary
Concomitant
Pancreatitis Chronic Hospitalization 5/1/2006 Female 10/1/2008 Physician Norway
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2008 Female 11/21/2008 Consumer United States
Primary
Concomitant
Injection Site Irritation 11/18/2008 Male 178 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Irritation 11/18/2008 Male 178 lb 3/14/2009 Other Health Professional United States
Primary
Concomitant
Sleep Disorder Other Serious 1/30/2009 Male 192 lb 4/24/2009 United States
Primary
Secondary
Concomitant
Withdrawal Syndrome 1/1/2008 5/19/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 5/20/2008 Female 5/22/2009 Consumer United Kingdom
Primary
Concomitant
Respiratory Distress Other Serious 4/30/2009 0 Female 5/21/2009 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 2/11/2009 Female 165 lb 6/8/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 2/11/2009 Female 165 lb 6/18/2009 Physician United States
Primary
Concomitant
Palpitations Hospitalization 83 Female 170 lb 7/2/2009 United States
Primary
Concomitant
Pain In Extremity Other Serious 76 Female 180 lb 7/13/2009 Consumer United States
Primary
Concomitant
Hypoglycaemia Death 6/15/2006 19 Male 130 lb 7/22/2009 United States
Primary
Concomitant
Incorrect Dose Administered 3/3/2007 Male 186 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/13/2007 Female 140 lb 9/11/2009 Consumer United States
Primary
Concomitant
Multiple Sclerosis Other Serious 2/1/2008 Female 9/19/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2009 76 Female 180 lb 9/25/2009 Consumer United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious 1/1/2007 Female 10/2/2009 United States
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2009 76 Female 180 lb 10/8/2009 Consumer United States
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 1/1/2009 Female 251 lb 10/30/2009 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 10/1/2009 Female 280 lb 11/6/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/30/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2008 Female 11/30/2009 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization Female 151 lb 12/9/2009 Consumer
Primary
Concomitant
Oropharyngeal Blistering 7/27/2009 66 Female 143 lb 12/21/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/12/2009 Female 15 lb 12/30/2009 United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Cholecystectomy Hospitalization 10/15/2009 Female 1/26/2010 United Kingdom
Primary
Concomitant
Ovarian Cyst Hospitalization 7/15/2009 Female 2/12/2010 United Kingdom
Primary
Concomitant
Drug Ineffective 60 Female 165 lb 2/22/2010 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2010 Female 194 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 4/1/2009 76 Female 180 lb 3/15/2010 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2010 Female 194 lb 3/15/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 13 Female 119 lb 3/17/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Atrophy Other Serious 3/14/2010 79 Female 150 lb 4/1/2010 Consumer United States
Primary
Secondary
Concomitant
Cholecystitis Acute Other Serious 10/15/2009 66 Female 4/2/2010 United Kingdom
Primary
Concomitant
Wound Necrosis Other Serious 7/15/2009 61 Female 4/7/2010 United Kingdom
Primary
Concomitant
Cholecystitis Acute Other Serious 10/15/2009 66 Female 4/15/2010 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 4/16/2010 Physician United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2010 64 Female 194 lb 4/29/2010 Physician United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/12/2010 United States
Primary
Secondary
Concomitant
Skin Atrophy Other Serious 3/14/2010 79 Female 150 lb 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Other Serious 44 Female 6/4/2010 Consumer United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 5/12/2010 79 Female 6/10/2010 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 5/12/2010 79 Female 6/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/1/2008 52 Female 265 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Potassium Increased Hospitalization 11/9/2009 81 Male 203 lb 6/16/2010 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/28/2009 51 Female 157 lb 6/25/2010 Consumer United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 17 Male 130 lb 7/2/2010 United States
Primary
Concomitant
Product Quality Issue 66 Male 7/14/2010 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 6/19/2010 69 Male 166 lb 7/13/2010 Physician United States
Primary
Concomitant
Surgery Other Serious Female 7/15/2010 Consumer United States
Primary
Concomitant
Wound Other Serious 4/28/2008 49 Female 220 lb 7/21/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 5/1/2010 73 Female 158 lb 7/27/2010 Physician United States
Primary
Concomitant
Osteomyelitis Other Serious 7/27/2010 58 Female 150 lb 8/5/2010 Physician Canada
Primary
Concomitant
Sputum Culture Positive Hospitalization 5/26/2010 81 Male 204 lb 8/4/2010 United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious Female 8/16/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/26/2009 9/7/2010 Other Health Professional Canada
Primary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 9/10/2010 Physician Sweden
Primary
Concomitant
Interacting
Vertigo Other Serious 1/1/2000 59 Female 110 lb 9/15/2010 Other Health Professional Sweden
Primary
Concomitant
Interacting
Skin Atrophy Other Serious 3/14/2010 79 Female 150 lb 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Lung Infiltration Other Serious 1/1/2000 59 Female 110 lb 9/23/2010
Primary
Secondary
Vertebral Wedging Other Serious 1/1/2000 61 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 7/27/2010 58 Female 150 lb 10/8/2010 Physician Canada
Primary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 10/13/2010 Physician Sweden
Primary
Concomitant
Interacting
Vertebral Wedging Other Serious 1/1/2000 61 Female 10/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 5/26/2010 81 Male 204 lb 10/15/2010 United States
Primary
Concomitant
Staphylococcus Test Positive Hospitalization 6/19/2010 69 Male 166 lb 11/5/2010 Physician United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 11/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Atrophy Other Serious 3/14/2010 79 Female 150 lb 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Pruritus 12/16/2010 Consumer United States
Primary
Concomitant
Nausea 6/22/2010 12/22/2010 Consumer United States
Primary
Concomitant
Injection Site Swelling 7/19/2010 12/22/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 8/5/2010 12/22/2010 Consumer United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2001 62 Female 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/1/2001 62 Female 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Mass 9/1/2010 49 Female 1/30/2011 Consumer United States
Primary
Concomitant
Nasopharyngitis 12/1/2010 53 Female 210 lb 1/30/2011 Consumer United States
Primary
Concomitant
Weight Increased 7/1/2010 69 Female 1/30/2011 Consumer United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 1/1/2003 52 Male 2/14/2011 Other Health Professional United States
Primary
Concomitant
Rash Vesicular 12/15/2010 83 Female 3/8/2011 Other Health Professional United States
Primary
Concomitant
Joint Injury Other Serious 2/14/2011 54 Female 216 lb 3/11/2011 Other Health Professional Canada
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/16/2010 14 Female 130 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/1/2001 62 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Eczema 1/1/2011 64 Female 207 lb 2/7/2011 Consumer United States
Primary
Concomitant
Bronchitis Other Serious 1/1/2003 52 Male 4/15/2011 Lawyer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2003 52 Male 4/25/2011 Other Health Professional United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Insomnia Death 1/1/2003 52 Male 5/19/2011 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/2/2005 49 Female 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Cognitive Disorder Other Serious 1/1/2009 46 Female 6/1/2011 Physician United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Influenza Other Serious 3/23/2011 58 Female 186 lb 6/9/2011 Pharmacist Canada
Primary
Concomitant
Malaise Other Serious 5/2/2005 49 Female 6/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiomegaly Other Serious 1/1/2010 52 Female 146 lb 6/16/2011 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2003 52 Male 6/17/2011 Lawyer United States
Primary
Concomitant
Arthralgia Other Serious 1/1/2010 52 Female 146 lb 6/23/2011 United States
Primary
Concomitant

Drug Data