Doxorubicin Hcl combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Disseminated Intravascular Coagulation Other Serious 12/21/2005 Female 42 lb 12/27/2005 United States
Primary
Secondary
Respiratory Distress Hospitalization 12/9/2005 72 Male 163 lb 1/13/2006 Consumer United States
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 11/12/2004 69 Male 181 lb 1/17/2006 Physician France
Primary
Secondary
Concomitant
Stomatitis Other Serious 11/21/2005 Female 138 lb 1/17/2006 United States
Primary
Secondary
Concomitant
Deafness Unilateral Hospitalization 12/2/2005 57 Female 1/24/2006 Physician France
Primary
Secondary
Vomiting Other Serious 1/19/2006 Female 125 lb 1/26/2006 United States
Primary
Secondary
Peripheral Motor Neuropathy Other Serious 1/4/2006 5 Female 35 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 3/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 2/11/2006 Female 179 lb 3/3/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 12/28/2004 75 Male 3/6/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/2004 68 Male 152 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 2/14/2006 Female 23 lb 3/7/2006 United States
Primary
Secondary
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 8/27/2005 63 Female 3/22/2006 Physician France
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 14 Male 3/27/2006 Physician United States
Primary
Secondary
Neutropenic Sepsis Other Serious 20 Male 139 lb 4/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Stomatitis Other Serious 14 Male 4/5/2006 Other Health Professional United States
Primary
Secondary
Transverse Sinus Thrombosis Hospitalization 12/9/2005 Female 43 lb 4/4/2006 Physician United States
Primary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/7/2006 40 Female 209 lb 4/14/2006 Physician France
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 3/1/2004 38 Female 4/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 11/23/2003 5 Female 4/28/2006 Physician Japan
Primary
Secondary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 5/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 2/24/2006 31 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/1/2003 43 Male 5/5/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/17/2005 52 Female 272 lb 5/11/2006 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 40 Female 5/19/2006 Consumer Japan
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 10 Female 6/3/2006 Physician Canada
Primary
Secondary
Treatment Related Secondary Malignancy Death 9/8/1998 58 Female 6/23/2006 Other Health Professional Finland
Primary
Secondary
Cerebral Haemorrhage Hospitalization 5/10/2006 49 Female 212 lb 6/29/2006 Other Health Professional France
Primary
Secondary
Medical Device Complication Other Serious 6/19/2006 12 Female 97 lb 6/26/2006 Physician Germany
Primary
Concomitant
Pancytopenia Death 5/10/2006 49 Female 216 lb 6/30/2006 France
Primary
Secondary
Sepsis Hospitalization 5/10/2006 49 Female 6/29/2006 France
Primary
Secondary
Movement Disorder Other Serious 6/19/2006 12 Female 97 lb 6/29/2006 Physician Germany
Primary
Concomitant
Pyrexia Death 5/10/2006 49 Female 212 lb 7/7/2006 Physician France
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 5/10/2006 49 Female 212 lb 7/19/2006 Other Health Professional France
Primary
Secondary
Visual Field Defect Other Serious Female 7/13/2006
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/18/2006 49 Male 146 lb 7/28/2006 Physician France
Primary
Secondary
Concomitant
Insulin-like Growth Factor Decreased Other Serious 15 Male 122 lb 7/28/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/30/2004 75 Male 8/2/2006 Physician France
Primary
Secondary
Concomitant
Cerebral Atrophy Hospitalization 11/9/2004 68 Female 106 lb 8/7/2006 Physician France
Primary
Secondary
Respiratory Failure Life Threatening 8/19/2005 74 Male 126 lb 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/23/2006 Male 53 lb 9/12/2006 United States
Primary
Secondary
Gastric Haemorrhage Life Threatening 8/30/2006 63 Male 9/26/2006 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 40 Male 10/6/2006 United States
Primary
Secondary
Spinal Compression Fracture Other Serious 11/1/1998 43 Male 10/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 7 Female 10/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Viral Load Increased Other Serious 11/1/1998 43 Male 10/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Injection Site Necrosis Hospitalization 8/21/2006 74 Male 220 lb 10/20/2006 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 7 Female 10/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Necrotising Colitis Hospitalization 7 Female 10/24/2006 Consumer United Kingdom
Primary
Secondary
Osteoporosis Other Serious 43 Male 10/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 8/1/2005 7 Female 10/26/2006 United Kingdom
Primary
Secondary
Intestinal Ischaemia Other Serious 9/11/2006 77 Male 11/2/2006 Other Health Professional Canada
Primary
Concomitant
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 11/3/2006 Physician Australia
Primary
Secondary
Vomiting Hospitalization 7 Female 10/26/2006 United Kingdom
Primary
Secondary
Osteoporosis Hospitalization 9/1/1998 43 Male 11/8/2006
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 11/1/1998 43 Male 11/14/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombosis 9/29/2006 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 53 Male 11/17/2006 Other Health Professional Japan
Primary
Concomitant
Mucosal Inflammation Hospitalization 11/17/2006 63 Female 12/11/2006 Consumer United States
Primary
Secondary
Mucosal Inflammation Other Serious 5/1/1999 55 Female 12/12/2006
Primary
Secondary
Lip And/or Oral Cavity Cancer Other Serious 5/1/1999 54 Female 12/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Other Serious 55 Female 12/18/2006 Consumer Hong Kong
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 43 Male 12/6/2006 United Kingdom
Primary
Secondary
Concomitant
Vaginal Inflammation Other Serious 55 Female 12/18/2006
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Hospitalization 43 Male 12/11/2006 United Kingdom
Primary
Secondary
Lip And/or Oral Cavity Cancer Other Serious 5/1/1999 54 Female 12/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 43 Male 12/13/2006 United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/23/2006 64 Female 132 lb 12/15/2006 Other Health Professional France
Primary
Secondary
Pancreatitis Other Serious 10/20/2006 17 Female 112 lb 12/18/2006 United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 12/29/2006 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/28/2006 61 Male 176 lb 12/21/2006 Physician France
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 11/27/2006 41 Male 152 lb 12/28/2006 Physician France
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 13 Male 10/7/2006 United States
Primary
Concomitant
Neurotoxicity Other Serious 20 Male 10/7/2006 United States
Primary
Concomitant
Neurotoxicity Other Serious 15 Female 10/7/2006 United States
Primary
Concomitant
Lip And/or Oral Cavity Cancer Other Serious 5/1/1999 Female 1/10/2007 United States
Primary
Secondary
Osteoporosis Hospitalization 11/1/1998 43 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 12/23/2006 56 Female 1/8/2007 Physician France
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 1/10/2007 Physician Finland
Primary
Secondary
Concomitant
Purpura Hospitalization 12/23/2006 56 Female 104 lb 1/24/2007 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/10/2006 75 Male 1/30/2007 Consumer United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 43 Male 1/30/2007 United Kingdom
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Life Threatening 8/30/2006 63 Male 1/31/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/3/2007 53 Male 179 lb 2/12/2007 Physician Israel
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 70 Female 2/12/2007 Consumer Israel
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 2/20/2007 Consumer Australia
Primary
Secondary
Thrombocytopenia Other Serious 2/20/2007 Consumer Australia
Primary
Secondary
Neutropenia Hospitalization 11/23/2006 64 Female 132 lb 2/9/2007 Other Health Professional France
Primary
Secondary
Thrombocytopenia Other Serious 2/22/2007 Australia
Primary
Secondary
Stem Cell Transplant Death Unknown 2/22/2007 Australia
Primary
Secondary
Metastasis Death 11 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Female 3/5/2007
Primary
Secondary
Metastasis Death 13 Female 3/5/2007
Primary
Secondary
Metastasis Death 12 Male 3/5/2007
Primary
Secondary
Metastasis Death 19 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Male 3/5/2007
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 11/27/2006 41 Male 152 lb 3/2/2007 Physician France
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/1/1998 43 Male 3/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Glioma Other Serious 2 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 2 Female 3/9/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 4 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 3 Female 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 5 Male 3/9/2007 Consumer Finland
Primary
Secondary
Uv Light Therapy Other Serious 49 Male 3/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Glioma Other Serious 2 Male 3/9/2007 Consumer Finland
Primary
Secondary
Pneumonitis Hospitalization 2/11/2007 65 Male 157 lb 3/2/2007 Physician France
Primary
Secondary
Concomitant
Glioma Other Serious 2 Female 3/9/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 3 Female 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 4 Male 3/9/2007 Consumer Finland
Primary
Secondary
Urinary Incontinence Other Serious 26 Female 3/7/2007 Australia
Primary
Secondary
Concomitant
Sepsis Other Serious 25 Male 3/7/2007 Australia
Primary
Secondary
Concomitant
Glioma Other Serious 5 Male 3/12/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 5 Male 3/12/2007 Consumer Finland
Primary
Secondary
Treatment Related Secondary Malignancy Death 11 Male 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 19 Male 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Male 3/1/2007 Germany
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 15 Female 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 12 Male 3/1/2007 Germany
Primary
Secondary
Glioma Death 13 Female 3/1/2007 Germany
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 5/13/2005 63 Female 3/13/2007 Consumer United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/13/2007 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/13/2007 Other Health Professional United States
Primary
Secondary
Spinal Compression Fracture Other Serious 43 Male 3/9/2007 United Kingdom
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Other Serious 11/1/1998 43 Male 3/9/2007 United Kingdom
Primary
Secondary
Malignant Neoplasm Progression Other Serious 5/13/2005 63 Female 3/16/2007 Consumer United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/19/2007 Other Health Professional United States
Primary
Secondary
Toxic Skin Eruption Other Serious 46 Male 3/13/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 49 Male 3/19/2007
Primary
Secondary
Vomiting Hospitalization 3/1/2007 52 Male 3/12/2007 Physician France
Primary
Secondary
Varices Oesophageal Other Serious 6/12/2006 78 Male 157 lb 3/14/2007 Other Health Professional United States
Primary
Concomitant
Spinal Fracture Hospitalization 11/1/1998 43 Male 3/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/23/2006 64 Female 132 lb 3/15/2007 France
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Male 3/16/2007 Germany
Primary
Secondary
Glioma Death 19 Male 3/16/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Female 3/16/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 12 Male 3/16/2007 Germany
Primary
Secondary
Glioma Death 13 Female 3/20/2007 Germany
Primary
Secondary
Glioma Death 11 Male 3/20/2007 Germany
Primary
Secondary
Spinal Fracture Other Serious 11/1/1998 43 Male 3/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/1/2007 52 Male 159 lb 3/23/2007 Physician France
Primary
Secondary
Neoplasm Malignant Death 15 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 13 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 11 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 15 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 19 Male 3/30/2007 Germany
Primary
Secondary
Neoplasm Malignant Death 12 Male 3/30/2007 Germany
Primary
Secondary
Concomitant

Drug Data