Benadryl combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myalgia Hospitalization 1/1/2005 Female 1/6/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2005 44 Female 1/4/2006 Other Health Professional United States
Primary
Concomitant
Drug Administration Error Hospitalization 10/1/2005 Female 140 lb 1/23/2006 Consumer United States
Primary
Concomitant
Suicide Attempt Hospitalization 11/16/2002 17 Female 125 lb 2/7/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2006 Female 147 lb 2/17/2006 Other Health Professional Canada
Primary
Concomitant
Peritonitis Other Serious 12/1/1998 Female 110 lb 2/17/2006 Physician United States
Primary
Concomitant
Vein Disorder Other Serious 9/7/2005 20 Female 121 lb 2/27/2006 Physician United States
Primary
Concomitant
Toe Deformity Other Serious 12/1/2001 Female 286 lb 3/7/2006 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 12/12/2005 Male 194 lb 3/17/2006 Other Health Professional Canada
Primary
Concomitant
Glomerulonephritis Membranous Other Serious Male 3/31/2006 Other Health Professional Canada
Primary
Concomitant
Visual Field Defect Other Serious 6/7/2001 35 Male 220 lb 4/14/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 119 lb 4/18/2006 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 119 lb 4/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 119 lb 4/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 6/7/2001 35 Male 220 lb 5/2/2006 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/6/2006 United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 4/1/1997 Female 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2001 Female 160 lb 5/11/2006 Consumer United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 4/17/2006 5 Female 38 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Peritonitis Other Serious 12/1/1998 Female 113 lb 5/19/2006 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/31/2006 United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 4/1/1997 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 115 lb 6/2/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 115 lb 6/2/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Somnolence 1/1/2005 42 Female 257 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 6/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 6/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 10/1/2005 Female 7/10/2006 Physician United States
Primary
Concomitant
Drug Clearance Decreased Required Intervention 2/24/2004 17 Male 152 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 7/20/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 66 Female 6/5/2006 United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Ulcer Other Serious 9/27/2005 Female 214 lb 8/2/2006 Other Health Professional Canada
Primary
Concomitant
Therapeutic Response Decreased Other Serious 6/1/2006 Female 154 lb 8/28/2006 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/18/2006 Female 140 lb 8/28/2006 Other Health Professional United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 9/7/2004 Female 159 lb 10/4/2006 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/18/2006 Female 140 lb 10/10/2006 Other Health Professional United States
Primary
Concomitant
Autoimmune Thyroiditis Hospitalization 10/11/2006 51 Female 10/18/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 8/18/2006 Female 140 lb 10/19/2006 Other Health Professional United States
Primary
Concomitant
Thyroiditis Fibrous Chronic Hospitalization 10/11/2006 51 Female 11/6/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thyroiditis Fibrous Chronic Hospitalization 10/11/2006 51 Female 11/9/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 10/1/2006 48 Female 191 lb 11/14/2006 Consumer United States
Primary
Secondary
White Blood Cells Urine Positive Other Serious 8/18/2005 Female 11/28/2006 Lawyer United States
Primary
Concomitant
Bronchitis Hospitalization 6/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 12/11/2006 Physician United States
Primary
Concomitant
Thyroiditis Fibrous Chronic Hospitalization 10/11/2006 51 Female 12/13/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 6/28/2005 59 Female 190 lb 1/9/2007 Consumer United States
Primary
Concomitant
Pain Other Serious 8/1/2005 56 Female 180 lb 12/5/2005 Other Health Professional United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 1/23/2007 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 6/28/2005 59 Female 190 lb 2/1/2007 Consumer United States
Primary
Concomitant
Temporal Lobe Epilepsy Hospitalization 2/7/2006 Male 2/21/2007 Other Health Professional Canada
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 8/31/2006 Female 105 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Other Serious 4/26/2006 Female 2/28/2007 Other Health Professional Canada
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 3/17/2007 Physician United States
Primary
Secondary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 10/11/2006 51 Female 3/19/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 3/20/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Lupus-like Syndrome Other Serious Female 210 lb 4/4/2007 Other Health Professional Canada
Primary
Concomitant
Wheezing Other Serious 12/15/2005 Male 228 lb 4/6/2007 Other Health Professional Canada
Primary
Concomitant
Neutropenic Sepsis Hospitalization 2/22/2007 62 Male 4/18/2007 Consumer United States
Primary
Concomitant
Throat Tightness Other Serious 1/23/2007 Female 4/20/2007 Other Health Professional Canada
Primary
Concomitant
Hypersensitivity 5/1/2007 72 Male 185 lb 6/4/2007 Consumer United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 7/5/2007 Female 176 lb 7/18/2007 Other Health Professional United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 Female 331 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Type Iii Immune Complex Mediated Reaction Other Serious 5/7/2007 1 Male 13 lb 7/19/2007 Physician United States
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 8/3/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 Female 229 lb 8/13/2007 Consumer United States
Primary
Secondary
Concomitant
Temperature Intolerance Other Serious 10/1/2006 Female 159 lb 8/20/2007 Other Health Professional Canada
Primary
Concomitant
Synovitis Other Serious 7/1/2007 Male 194 lb 8/24/2007 Other Health Professional United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 Female 331 lb 9/11/2007 Consumer United States
Primary
Secondary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/30/2007 43 Male 233 lb 10/4/2007 Pharmacist United States
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/2/2007 Female 176 lb 10/26/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 Female 229 lb 10/30/2007 Consumer United States
Primary
Secondary
Concomitant
Rash 4/24/2007 59 Female 11/13/2007 Consumer United States
Primary
Concomitant
Peritonitis Life Threatening 11/4/2007 Female 123 lb 11/16/2007 Other Health Professional Colombia
Primary
Concomitant
Peritonitis Life Threatening 11/4/2007 Female 123 lb 11/30/2007 Other Health Professional Colombia
Primary
Concomitant
Staring Hospitalization 11/13/2007 Female 104 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/1/2007 1 Male 11/29/2007 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 11/25/2007 1 Male 23 lb 12/10/2007 Pharmacist United States
Primary
Concomitant
Glomerulonephritis Minimal Lesion Other Serious 9/1/2007 Female 151 lb 12/14/2007 Physician United States
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 8/1/2007 1 Male 22 lb 12/11/2007 Physician United States
Primary
Concomitant
Weaning Failure Hospitalization 3/19/2007 1 Male 12 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
No Adverse Reaction 8/30/2007 68 Female 132 lb 12/21/2007 Consumer United States
Primary
Concomitant
Tracheostomy Infection Hospitalization 11/25/2007 1 Male 23 lb 12/21/2007 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2006 75 Female 128 lb 1/7/2008 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2007 Female 1/7/2008 United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2007 Female 1/8/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2007 77 Female 123 lb 11/28/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/25/2008 Physician United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 4/1/2007 64 Female 107 lb 1/30/2008 Consumer United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/2004 Female 180 lb 2/11/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 2/12/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 2/22/2008 Consumer United States
Primary
Concomitant
Interacting
Oedema Peripheral Other Serious 2/4/2008 Female 194 lb 2/27/2008 Pharmacist United States
Primary
Concomitant
Dizziness Male 197 lb 3/15/2008 United States
Primary
Concomitant
Rash Macular 10/28/2007 Female 220 lb 3/15/2008 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 4/1/2007 Female 107 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 12/21/2006 Female 179 lb 3/28/2008 Physician United States
Primary
Concomitant
Haematochezia Other Serious 1/1/2008 70 Female 141 lb 3/28/2008 Other Health Professional Canada
Primary
Concomitant
Vision Blurred Other Serious 2/19/2008 Female 4/3/2008 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/19/2007 1 Male 12 lb 4/11/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia 4/17/2008 36 Female 6/12/2008 Consumer Puerto Rico
Primary
Concomitant
Swelling Face 3/4/2008 Female 6/12/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 6/25/2008 Physician United States
Primary
Secondary
Concomitant
Renal Pain Other Serious 3/1/2008 Female 139 lb 7/2/2008 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Hospitalization Male 7/18/2008 Consumer United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 5/19/2004 Female 184 lb 8/8/2008 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/7/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 8/12/2008 Canada
Primary
Secondary
Concomitant
Tremor Other Serious 7/31/2008 37 Female 8/15/2008 Other Health Professional United States
Primary
Concomitant
Lymphadenopathy 1/1/2008 Female 198 lb 9/12/2008 Physician United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 11/12/2007 Male 275 lb 9/22/2008 Physician United States
Primary
Concomitant
Pruritus Hospitalization 9/1/2007 29 Female 9/25/2008 Other Health Professional United States
Primary
Concomitant
Periorbital Oedema 59 Female 9/25/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 10/3/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2008 Female 10/24/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Hospitalization 4/1/2008 Female 10/24/2008 Physician United States
Primary
Secondary
Concomitant
Euphoric Mood Other Serious 10/1/2008 Male 90 lb 11/6/2008 Consumer United States
Primary
Concomitant
Pneumonia Legionella Hospitalization 10/1/2008 Female 11/7/2008 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 2/27/2007 Female 71 lb 11/12/2008 Physician United States
Primary
Secondary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/13/2008 Female 164 lb 11/26/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity 3/1/2008 Female 178 lb 12/12/2008 Consumer United States
Primary
Concomitant
Somnolence 10/1/2007 Female 12/15/2008 Consumer United States
Primary
Concomitant
Osteopenia Other Serious 5/11/2007 Female 180 lb 12/19/2008 Physician United States
Primary
Concomitant
Vomiting 1/1/2008 56 Female 249 lb 12/31/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/13/2008 Female 164 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/6/2008 2 Male 29 lb 12/29/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2008 Female 80 lb 1/23/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 8/10/2007 1 Male 22 lb 1/20/2009 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2007 Female 1/29/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Euphoric Mood Other Serious 10/1/2008 Male 90 lb 2/9/2009 Physician United States
Primary
Concomitant
Somnolence Hospitalization 1/30/2009 Male 166 lb 2/6/2009 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/20/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 1/30/2009 Male 166 lb 2/17/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2008 Female 3/1/2009 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/7/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/30/2009 Male 166 lb 3/10/2009 United States
Primary
Secondary
Concomitant
Vaginal Fistula Other Serious 1/1/2008 Female 118 lb 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Fistula Other Serious 1/1/2008 Female 118 lb 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 1/1/2008 Female 175 lb 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/30/2009 Male 166 lb 3/20/2009 United States
Primary
Secondary
Concomitant

Drug Data