Methotrexate combined with Zolpidem Tartrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Other Serious 8/1/2005 Female 150 lb 4/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 2/1/2003 33 Female 117 lb 5/4/2006 Physician Germany
Primary
Secondary
Concomitant
Heart Rate Decreased Hospitalization 9/1/2006 Female 217 lb 10/18/2006 Consumer United States
Primary
Secondary
Concomitant
Heart Rate Decreased Hospitalization 9/1/2006 Female 217 lb 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2006 61 Female 120 lb 1/2/2007 Other Health Professional United States
Primary
Concomitant
Death Death 2/8/2007 Female 4/6/2007 United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2007 83 Female 7/10/2007 Consumer United States
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 8/28/2007 Physician Japan
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 8/1/2007 Female 209 lb 9/14/2007 Consumer United States
Primary
Concomitant
Tibia Fracture Hospitalization 3/1/2004 Female 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Legionella Other Serious 11/8/2007 85 143 lb 11/21/2007 Physician Israel
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/1/2004 Female 168 lb 12/3/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/1/2007 Female 227 lb 12/14/2007 Consumer United States
Primary
Concomitant
Vertigo 9/1/2007 Male 12/14/2007 United States
Primary
Concomitant
Overdose Hospitalization 10/16/2007 Female 180 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Injection Site Pruritus 10/31/2007 Female 12/14/2007 United States
Primary
Concomitant
Injection Site Irritation 3/1/2007 Female 130 lb 12/15/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 11/1/2007 66 Female 1/17/2008 Physician Sweden
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 1/22/2008 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 11/1/2007 66 Female 2/4/2008 Physician Sweden
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 2/11/2008 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 11/1/2007 66 Female 2/15/2008 Other Health Professional Sweden
Primary
Concomitant
Weight Increased 1/1/2003 Female 223 lb 3/14/2008 United States
Primary
Concomitant
Accidental Exposure 11/8/2006 Female 220 lb 3/14/2008 Consumer United States
Primary
Concomitant
Pain 10/1/2007 Female 452 lb 3/14/2008 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 10/1/2007 Female 165 lb 3/14/2008 United States
Primary
Concomitant
Insomnia 12/10/2007 Female 130 lb 3/14/2008 United States
Primary
Concomitant
Somnolence 12/21/2007 Female 172 lb 3/14/2008 Consumer United States
Primary
Concomitant
Smear Cervix Abnormal 3/10/2007 Female 178 lb 3/15/2008 Physician United States
Primary
Concomitant
Injection Site Pruritus 12/29/2007 Female 200 lb 3/15/2008 Consumer United States
Primary
Concomitant
Nasopharyngitis 1/28/2008 Female 196 lb 3/15/2008 United States
Primary
Concomitant
Accidental Exposure 1/24/2008 Female 115 lb 3/15/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 10/1/2007 Female 139 lb 3/15/2008 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 5/1/2007 Female 159 lb 4/8/2008 Physician United States
Primary
Concomitant
Overdose Hospitalization 10/16/2007 Female 180 lb 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Nasopharyngitis 3/6/2008 Female 285 lb 6/12/2008 United States
Primary
Concomitant
Arthralgia 3/7/2008 Female 240 lb 6/12/2008 United States
Primary
Concomitant
Rash Pruritic 4/22/2008 Female 180 lb 6/13/2008 Consumer United States
Primary
Concomitant
Weight Increased Male 6/13/2008 Pharmacist United States
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 4/6/2008 Male 162 lb 6/23/2008 United States
Primary
Concomitant
Shoulder Operation Other Serious 6/19/2008 Female 138 lb 6/27/2008 Consumer United States
Primary
Concomitant
Hernia Other Serious 3/12/2008 Female 165 lb 7/3/2008 United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 6/19/2008 Female 138 lb 7/11/2008 Consumer United States
Primary
Concomitant
Troponin Increased Hospitalization 6/8/2008 69 Female 123 lb 7/7/2008 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/3/2008 Female 115 lb 7/11/2008 Japan
Primary
Concomitant
Lung Infiltration Hospitalization 9/11/2007 45 Female 7/16/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pemphigoid Other Serious 4/6/2008 Male 162 lb 7/17/2008 United States
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/18/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/18/2008 Japan
Primary
Concomitant
Pemphigoid Other Serious 4/6/2008 Male 162 lb 7/22/2008 United States
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/25/2008 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 9/11/2007 45 Female 8/5/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/11/2007 Female 8/25/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Wound Other Serious 4/6/2008 Male 162 lb 8/27/2008 United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 5/1/2006 Female 250 lb 9/11/2008 United States
Primary
Concomitant
Psoriasis 10/2/2006 Female 115 lb 9/12/2008 Consumer United States
Primary
Concomitant
Varicella 6/1/2008 Female 125 lb 9/12/2008 Puerto Rico
Primary
Secondary
Concomitant
Accidental Exposure 6/17/2008 Female 9/12/2008 Physician United States
Primary
Concomitant
Pain 6/27/2008 Male 210 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 7/14/2008 163 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2004 Female 211 lb 9/12/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection 5/1/2008 Female 220 lb 9/13/2008 United States
Primary
Concomitant
Injection Site Urticaria 7/1/2008 Female 111 lb 9/13/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 4/1/2008 Female 265 lb 9/13/2008 Consumer United States
Primary
Concomitant
Sinus Operation Other Serious 5/27/2008 Female 215 lb 9/16/2008 Consumer United States
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 9/24/2008 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 7/1/2008 Female 326 lb 9/25/2008 Consumer United States
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 10/17/2008 Japan
Primary
Concomitant
Pleural Effusion Life Threatening 8/7/2008 Female 77 lb 10/31/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/4/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/7/2008 Physician Japan
Primary
Concomitant
Nausea Other Serious 5/1/2008 57 Male 11/17/2008 Physician Sweden
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/21/2008 Physician Japan
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 9/22/2008 Female 12/5/2008 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Female 139 lb 12/8/2008 Consumer United States
Primary
Concomitant
Vomiting 8/27/2008 Female 98 lb 12/12/2008 United States
Primary
Secondary
Concomitant
No Therapeutic Response 4/1/2008 Female 170 lb 12/12/2008 Physician United States
Primary
Concomitant
Accidental Exposure 9/5/2008 Male 201 lb 12/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain Male 183 lb 12/12/2008 Consumer United States
Primary
Concomitant
Pain 9/27/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Skin Infection 9/1/2008 Male 12/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2006 Male 12/12/2008 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 3/16/2008 Male 280 lb 12/15/2008 Other Health Professional United States
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 9/22/2008 Female 12/17/2008 Physician United Kingdom
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 12/19/2008 Japan
Primary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 2/12/2009 Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
Pericarditis Hospitalization 5/7/2008 Male 2/20/2009 Other Health Professional Sweden
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 12/12/2008 Female 282 lb 3/13/2009 United States
Primary
Concomitant
Pain In Extremity 11/1/2008 Female 3/14/2009 Consumer United States
Primary
Concomitant
Subcutaneous Emphysema Hospitalization 4/3/2009 Male 4/30/2009 Japan
Primary
Secondary
Concomitant
Dizziness Other Serious 4/2/2009 Female 130 lb 5/6/2009 Physician United States
Primary
Concomitant
Subcutaneous Emphysema Hospitalization 4/3/2009 Male 5/14/2009 Japan
Primary
Secondary
Concomitant
Subcutaneous Emphysema Hospitalization 4/3/2009 Male 5/27/2009 Japan
Primary
Secondary
Concomitant
Subcutaneous Emphysema Hospitalization 3/21/2009 Male 6/5/2009 Japan
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 6/9/2009 Japan
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 11/1/2008 55 Female 137 lb 6/15/2009 Physician Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/18/2009 Male 106 lb 7/13/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/18/2009 Male 106 lb 7/21/2009 Japan
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/18/2009 Male 106 lb 8/20/2009 Japan
Primary
Secondary
Concomitant
Weight Increased 1/1/2006 Female 211 lb 8/25/2009 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 3/19/2009 Female 8/26/2009 Japan
Primary
Concomitant
Pyrexia Other Serious 3/19/2009 Female 9/4/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/18/2009 Male 106 lb 9/9/2009 Japan
Primary
Secondary
Concomitant
Incorrect Dose Administered 3/28/2007 Female 135 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 8/30/2007 Female 141 lb 9/12/2009 Consumer United States
Primary
Concomitant
Accidental Needle Stick 11/8/2006 Female 220 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Irritation 3/1/2007 Female 130 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pain 10/1/2007 Female 452 lb 9/12/2009 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered 1/24/2008 Female 115 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 6/17/2008 Female 9/12/2009 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 4/1/2008 Female 170 lb 9/12/2009 Physician United States
Primary
Concomitant
Injection Site Urticaria 7/1/2008 Female 111 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 7/14/2008 163 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain Male 183 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 9/5/2008 Male 201 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2004 Female 211 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 3/19/2009 Female 9/18/2009 Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 7/2/2009 Male 116 lb 9/22/2009 Japan
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 9/25/2009 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 3/19/2009 Female 10/23/2009 Japan
Primary
Secondary
Concomitant
Vitamin D Decreased Hospitalization 8/11/2008 48 Female 212 lb 11/11/2009 Physician United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 7/2/2009 Male 116 lb 11/23/2009 Japan
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/12/2008 Female 140 lb 12/4/2009 Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 7/2/2009 Male 116 lb 12/21/2009 Japan
Primary
Secondary
Concomitant
Pain Other Serious 1/6/2010 Female 115 lb 1/28/2010 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 3/19/2009 Female 2/5/2010 Japan
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Vitamin D Decreased Hospitalization 8/11/2008 48 Female 212 lb 2/26/2010 Physician United States
Primary
Concomitant
Pain Other Serious 1/6/2010 Female 115 lb 2/26/2010 Japan
Primary
Secondary
Concomitant
Shock Other Serious 1/6/2010 Female 115 lb 3/26/2010 Japan
Primary
Secondary
Concomitant
Gynaecomastia Hospitalization 8/1/2009 45 Male 4/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 3/24/2009 53 Female 160 lb 4/16/2010 Physician United States
Primary
Concomitant
Sepsis Other Serious 3/19/2009 68 Female 6/2/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 1/6/2010 67 Female 115 lb 6/17/2010 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Other Serious 6/1/2010 65 Female 6/29/2010 Japan
Primary
Concomitant
Large Intestine Carcinoma Other Serious 6/1/2010 65 Female 7/7/2010 Japan
Primary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 7/20/2010 Other Health Professional Japan
Primary
Concomitant
Tooth Fracture Other Serious 12/1/2007 72 Male 172 lb 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Wound Other Serious 4/28/2008 49 Female 220 lb 7/21/2010 Consumer United States
Primary
Concomitant
Colon Cancer Hospitalization 6/1/2010 65 Female 7/16/2010 Japan
Primary
Concomitant
Urticaria Other Serious 1/1/2005 62 Female 220 lb 7/29/2010 Consumer United States
Primary
Concomitant
Urticaria Other Serious 1/1/2005 62 Female 220 lb 8/9/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 3/19/2009 68 Female 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Other Serious 6/8/2010 65 Female 8/10/2010 Japan
Primary
Concomitant
Shock Other Serious 1/6/2010 67 Female 115 lb 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/2005 62 Female 220 lb 8/27/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 9/1/2010 Other Health Professional Japan
Primary
Concomitant

Drug Data