Decadron combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tongue Disorder Other Serious 12/5/2005 Male 216 lb 12/27/2005 United States
Primary
Secondary
Tumour Lysis Syndrome Required Intervention 10/14/2005 55 Male 11/15/2005 Other Health Professional United States
Primary
Concomitant
Blood Creatinine Increased Required Intervention 10/10/2005 32 Male 11/15/2005 Other Health Professional United States
Primary
Concomitant
Renal Failure Required Intervention 11/9/2005 46 Male 11/15/2005 United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 2/3/2006 Physician Japan
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 3/2/2006 Physician Japan
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 3/8/2006 Physician Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 3/10/2006 Physician Japan
Primary
Secondary
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/24/2006 65 Male 134 lb 4/11/2006 Physician Japan
Primary
Concomitant
Eye Movement Disorder 1/1/2006 47 Female 4/28/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Death 46 Male 5/2/2006 Norway
Primary
Secondary
Ventricular Hypertrophy Life Threatening 3/27/2006 Female 116 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 6 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 8/3/2005 43 Male 4/28/2006 Physician Japan
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/6/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/20/2006 70 Female 117 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Life Threatening 8/3/2005 43 Male 6/8/2006 Physician Japan
Primary
Concomitant
Pain In Jaw Other Serious 2/21/2006 78 Female 6/26/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/15/2006 Female 6/28/2006 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 1/1/2002 16 Female 95 lb 7/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 2/21/2006 78 Female 8/4/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/24/2005 85 Female 8/14/2006 Physician United States
Primary
Concomitant
Cataract Other Serious 51 Male 270 lb 9/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 5 Female 10/5/2006 Physician Japan
Primary
Concomitant
Sepsis Death 39 Male 10/17/2006 Physician United States
Primary
Concomitant
Necrotising Colitis Hospitalization 7 Female 10/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Mucormycosis Death 10/13/2006 Physician United States
Primary
Concomitant
Multi-organ Failure Other Serious 5 Female 10/27/2006 Physician Japan
Primary
Concomitant
Weight Increased Required Intervention 9/18/2006 Male 36 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Hyponatraemia Required Intervention 9/5/2006 8 Male 61 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Cataract Other Serious 51 Male 269 lb 11/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/17/2006 61 Female 11/2/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 17 Male 11/6/2006 Physician Poland
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 5 Female 11/8/2006 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 11/26/2003 61 Male 168 lb 11/6/2006 Physician United States
Primary
Secondary
Incorrect Dose Administered Other Serious 51 Male 270 lb 11/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/4/2002 56 Female 11/20/2006 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 51 Male 270 lb 10/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2003 Female 12/13/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 11/9/2005 46 Male 10/7/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/29/2005 40 Female 10/7/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/29/2006 17 Female 1/10/2007 Consumer
Primary
Concomitant
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 1/10/2007 Physician Finland
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 1/23/2007 United States
Primary
Secondary
Concomitant
Lymphohistiocytosis Hospitalization 0 Female 3/1/2007 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 3/17/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/27/2007 35 Female 3/22/2007 Physician Japan
Primary
Secondary
Concomitant
Streptococcal Bacteraemia Death 12 Female 4/2/2007 Physician Japan
Primary
Concomitant
Venous Thrombosis Limb Other Serious 31 Female 4/2/2007 Physician Japan
Primary
Secondary
Cataract Other Serious 51 Male 270 lb 1/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 31 Female 4/5/2007 Physician Japan
Primary
Secondary
Streptococcal Bacteraemia Death 12 Female 4/6/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/27/2007 35 Female 4/4/2007 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 31 Female 4/24/2007 Physician Japan
Primary
Secondary
Vomiting Hospitalization 1/27/2007 35 Female 4/19/2007 Physician Japan
Primary
Secondary
Concomitant
Streptococcal Bacteraemia Death 12 Female 5/7/2007 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Hospitalization 6/18/2005 15 Female 108 lb 6/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 7/9/2007 United Kingdom
Primary
Concomitant
Metastasis Hospitalization 1/1/2002 67 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Cachexia Death 57 8/3/2007 Netherlands
Primary
Secondary
Concomitant
Cachexia Death 60 8/3/2007 Netherlands
Primary
Secondary
Concomitant
Metastasis Hospitalization 1/1/2002 40 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Platelet Count Decreased Life Threatening 12/18/2006 20 Male 115 lb 8/2/2007 Physician Japan
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/27/2007 8 Male 44 lb 8/27/2007 Physician Japan
Primary
Secondary
Concomitant
Metastasis Hospitalization 1/1/2002 40 Female 9/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Hepatitis B Death 3/1/2006 54 Male 9/11/2007 Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 2/1/2006 54 Male 9/18/2007 Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 2/1/2006 54 Male 10/2/2007 Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/30/2007 43 Male 233 lb 10/4/2007 Pharmacist United States
Primary
Concomitant
Rash 4/24/2007 59 Female 11/13/2007 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 3/28/2007 29 Male 163 lb 12/14/2007 Physician Japan
Primary
Concomitant
Infection Death 18 Female 12/28/2007 Physician Netherlands
Primary
Concomitant
Infection Death 15 Female 12/28/2007 Physician Netherlands
Primary
Concomitant
Infection Death 16 Male 12/28/2007 Physician Netherlands
Primary
Concomitant
Infection Death 3 Male 12/28/2007 Physician Netherlands
Primary
Concomitant
Infection Death 5 Female 12/28/2007 Physician Netherlands
Primary
Concomitant
Infection Death 15 Male 12/28/2007 Physician Netherlands
Primary
Concomitant
Salmonellosis Death 3 Male 12/28/2007 Physician Netherlands
Primary
Concomitant
Pulmonary Toxicity Hospitalization 7/15/2007 58 Female 143 lb 11/5/2007 Pharmacist United States
Primary
Concomitant
Metastases To Skin Life Threatening 12/18/2006 20 Male 115 lb 1/4/2008 Physician Japan
Primary
Concomitant
Cataract Other Serious 51 Male 270 lb 1/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mass Hospitalization 2/4/2008 Physician Hong Kong
Primary
Secondary
Vomiting Hospitalization 3/15/2008 43 Female 128 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/21/2007 25 Male 112 lb 6/4/2008 Physician Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization Female 103 lb 6/18/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/16/2007 Male 163 lb 6/20/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 6/27/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Pain Other Serious 3/1/2008 Female 139 lb 7/2/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/21/2007 25 Male 112 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/22/2008 Female 103 lb 7/8/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 7/11/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Other Serious 75 Female 7/21/2008 Physician Japan
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Other Serious 75 Female 7/31/2008 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 7/28/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 2 Male 8/19/2008 United Kingdom
Primary
Secondary
Choriomeningitis Lymphocytic Hospitalization 15 Female 10/17/2008 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 10/17/2008 Consumer United States
Primary
Secondary
Concomitant
Choriomeningitis Lymphocytic Hospitalization 15 Female 10/20/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 4/30/2008 Female 103 lb 10/23/2008 Consumer United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2007 20 Male 10/24/2008 Physician Japan
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2007 20 Male 10/24/2008 Physician Japan
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 10/29/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 29 Male 10/31/2008 Physician Argentina
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 11/5/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/30/2008 Female 103 lb 11/18/2008 Consumer United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 0 Female 11/18/2008 Other Health Professional United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 11/24/2008 Consumer United States
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 1/1/2007 16 Female 11/21/2008 Physician United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/3/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/27/2007 8 Male 44 lb 12/9/2008 Physician Japan
Primary
Secondary
Concomitant
Yellow Skin 6/27/2008 Female 12/13/2008 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 12/15/2008 China
Primary
Secondary
Vomiting Other Serious 10/23/2007 16 Female 156 lb 12/16/2008 Physician United States
Primary
Secondary
Drug Ineffective Death 1/1/2005 73 Female 12/26/2008 Physician Israel
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/29/2008 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Male 1/6/2009 Physician Sweden
Primary
Concomitant
Drug Ineffective Other Serious Male 1/6/2009 Physician Sweden
Primary
Concomitant
Loss Of Consciousness Life Threatening 11/13/2008 62 Male 12/22/2008 Japan
Primary
Concomitant
Loss Of Consciousness Life Threatening 11/13/2008 62 Male 12/23/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 9/2/2008 Male 2/9/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/15/2008 Male 3/6/2009 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/1/2007 63 Male 5/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/2/2008 56 Male 108 lb 5/18/2009 Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/1/2008 57 Male 108 lb 6/5/2009 Japan
Primary
Concomitant
Nausea Other Serious 10/27/2008 58 Female 106 lb 6/9/2009 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 4/26/2007 Male 112 lb 6/10/2009 Other Health Professional Japan
Primary
Concomitant
Malaise Life Threatening 3/1/2007 Male 134 lb 6/18/2009 Physician Japan
Primary
Concomitant
Vanillyl Mandelic Acid Urine Increased Death 6/12/2009 4 Male 40 lb 6/15/2009 Physician United States
Primary
Concomitant
Surgery Other Serious Female 7/6/2009 Consumer Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/19/2006 9 Male 51 lb 7/10/2009 Physician Japan
Primary
Secondary
Concomitant
Immunosuppression Hospitalization 7/1/1997 30 Male 7/20/2009 Other Health Professional Japan
Primary
Secondary
Pneumonia Hospitalization 7/1/1997 30 Male 7/22/2009 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 2/27/2007 8 Male 44 lb 7/27/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2008 Male 330 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/1/2007 63 Male 8/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 10/29/2008 58 Female 106 lb 9/8/2009 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/2/2008 56 Male 108 lb 9/15/2009 Japan
Primary
Concomitant
Nausea Other Serious 10/29/2008 58 Female 106 lb 9/15/2009 Physician Japan
Primary
Secondary
Concomitant

Drug Data