Altace combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Metastatic Neoplasm Life Threatening 10/11/2005 Female 1/24/2006 Physician Canada
Primary
Concomitant
Weight Decreased Hospitalization 5/24/2005 83 Female 3/24/2006 Canada
Primary
Concomitant
Myocardial Infarction Other Serious 5/1/2004 76 Male 168 lb 4/19/2006 Lawyer United States
Primary
Concomitant
Paraesthesia Other Serious 12/30/2005 55 Female 166 lb 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Shoulder Pain Hospitalization 65 Female 5/26/2006 Other Health Professional Canada
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization Male 6/12/2006 Physician United States
Primary
Concomitant
Lipase Increased Other Serious 4/1/2006 Female 6/30/2006 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/9/2006 Female 125 lb 8/7/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 3/1/2006 Female 225 lb 9/15/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/30/2005 55 Female 166 lb 9/11/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/26/2006 89 Female 9/18/2006 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/1/2006 46 Female 9/20/2006 Physician United States
Primary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 9/21/2006 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/9/2006 Female 125 lb 10/6/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Male 10/11/2006 Physician United States
Primary
Concomitant
Skin Infection Hospitalization 5/1/2005 Female 305 lb 10/19/2006 Physician United States
Primary
Concomitant
Wheezing Other Serious 9/1/2006 Female 11/8/2006 Physician
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 2/5/2006 Female 118 lb 12/13/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/15/2005 Male 248 lb 12/13/2006 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 2/1/2006 Male 12/21/2006 Physician United States
Primary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 12/19/2006 Consumer United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 12/19/2006 Consumer United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 10/23/2006 57 Male 1/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/1/2005 63 Female 157 lb 11/28/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/26/2006 Female 171 lb 1/25/2007 Physician United States
Primary
Concomitant
Suffocation Feeling Other Serious 3/2/2006 67 Female 2/5/2007 Other Health Professional Canada
Primary
Concomitant
Embolism Other Serious 1/25/2007 54 Male 164 lb 2/6/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Life Threatening 1/12/2007 72 Female 226 lb 3/8/2007 Physician United States
Primary
Concomitant
Septic Embolus Hospitalization 12/1/2005 Female 3/26/2007 Physician United States
Primary
Concomitant
Coronary Artery Occlusion Life Threatening 1/12/2007 72 Female 226 lb 3/21/2007 Other Health Professional United States
Primary
Concomitant
Histoplasmosis Other Serious 12/1/2006 Female 266 lb 4/2/2007 Physician United States
Primary
Concomitant
Myalgia Hospitalization 10/1/2005 52 Male 182 lb 4/2/2007 Consumer United States
Primary
Concomitant
Oesophagitis Ulcerative Hospitalization 12/1/2006 Female 203 lb 4/3/2007 Physician Canada
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/5/2006 Female 4/5/2007 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Female 115 lb 6/25/2007 Consumer United States
Primary
Concomitant
Bowen's Disease Other Serious 6/1/2005 83 Female 7/5/2007 Other Health Professional United States
Primary
Concomitant
Lacunar Infarction Other Serious 12/30/2005 Female 166 lb 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/28/2007 51 Male 186 lb 8/22/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 5/28/2007 51 Male 186 lb 9/7/2007 Physician United States
Primary
Concomitant
Weight Decreased 8/26/2005 54 Female 12/15/2006 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 10/22/2007 Physician United States
Primary
Concomitant
Pulmonary Mass Other Serious 10/16/2007 Male 207 lb 10/26/2007 Other Health Professional Canada
Primary
Concomitant
Pneumonia Other Serious 1/1/2005 67 Male 229 lb 11/9/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/1/2006 Male 11/12/2007 Physician United States
Primary
Concomitant
Rash 4/24/2007 59 Female 11/13/2007 Consumer United States
Primary
Concomitant
Pulmonary Mass Other Serious 10/16/2007 Male 207 lb 11/21/2007 Other Health Professional Canada
Primary
Concomitant
Superficial Spreading Melanoma Stage Iv Other Serious 10/3/2007 Female 12/6/2007 Physician United States
Primary
Concomitant
Bowen's Disease Other Serious 4/1/2007 83 Female 12/17/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 70 Female 163 lb 12/17/2007 United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 12/18/2007 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 1/24/2008 Physician United States
Primary
Concomitant
Bowen's Disease Other Serious 4/1/2007 85 Female 2/5/2008 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 12/19/2007 72 Female 150 lb 2/6/2008 Physician United States
Primary
Concomitant
Diastolic Dysfunction Other Serious 12/1/2007 Female 2/20/2008 Physician United States
Primary
Concomitant
Hemiparesis Hospitalization 57 Female 249 lb 2/20/2008 Consumer United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 2/28/2008 Physician United States
Primary
Concomitant
Hemiparesis Hospitalization 1/30/2008 57 Female 249 lb 4/3/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 Female 143 lb 4/23/2008 Consumer United States
Primary
Concomitant
Palpitations Other Serious 3/1/2008 Female 180 lb 6/4/2008 Physician Canada
Primary
Concomitant
Skin Reaction Other Serious 4/1/2008 Female 119 lb 7/2/2008 United States
Primary
Concomitant
Hypoaesthesia Hospitalization Male 7/18/2008 Consumer United States
Primary
Concomitant
Spinal Compression Fracture Other Serious 10/19/2006 Male 196 lb 7/18/2008 Canada
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 4/11/2008 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Cyst Other Serious 4/15/2008 Female 174 lb 8/13/2008 Other Health Professional Canada
Primary
Concomitant
Tooth Loss Disability 12/18/2001 64 Female 8/15/2008 Other Health Professional United States
Primary
Concomitant
Tooth Loss Disability 12/18/2001 64 Female 9/12/2008 Other Health Professional United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 11/12/2007 Male 275 lb 9/22/2008 Physician United States
Primary
Concomitant
Vertigo Positional Disability 12/18/2001 64 Female 11/3/2008 Other Health Professional United States
Primary
Concomitant
Mass Other Serious 12/1/2007 Female 11/24/2008 Consumer Canada
Primary
Concomitant
Pseudoporphyria Other Serious 65 Female 11/25/2008 Physician United States
Primary
Concomitant
Ventricular Extrasystoles 9/26/2008 53 Female 11/26/2008 Consumer United States
Primary
Concomitant
Superficial Spreading Melanoma Stage Iv Other Serious 10/3/2007 Female 12/1/2008 Physician United States
Primary
Concomitant
Vomiting 1/1/2008 58 Female 140 lb 12/17/2008 Consumer United States
Primary
Concomitant
Stent Placement Other Serious 8/1/2006 Male 12/22/2008 United States
Primary
Concomitant
Septic Embolus Other Serious 10/31/2008 Male 160 lb 12/26/2008 Canada
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 2/26/2009 United States
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 3/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 11/6/2008 67 Female 3/12/2009 Consumer France
Primary
Secondary
Concomitant
Skin Atrophy Hospitalization 1/9/2009 Female 3/6/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 12/1/2008 Male 220 lb 3/14/2009 United States
Primary
Concomitant
Vertigo Positional Disability 1/1/2001 60 Female 3/18/2009 Other Health Professional United States
Primary
Concomitant
Tendon Rupture Required Intervention 12/1/2007 74 Male 195 lb 3/27/2009 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 3/15/2009 Female 171 lb 5/12/2009 Canada
Primary
Concomitant
Vertigo Positional Disability 1/1/2001 60 Female 5/19/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased 3/1/2009 Male 225 lb 6/12/2009 United States
Primary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/17/2009 Other Health Professional Canada
Primary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Urinary Tract Infection 7/31/2009 Female 180 lb 9/19/2009 Physician
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/22/2003 42 Female 246 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 9/16/2009 77 Male 155 lb 10/9/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Endometrial Cancer Metastatic Other Serious Female 261 lb 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Haemothorax Hospitalization 10/20/2009 Male 247 lb 11/23/2009 Physician Canada
Primary
Concomitant
Skin Burning Sensation Female 220 lb 11/25/2009 United States
Primary
Concomitant
Volvulus Other Serious 11/17/2009 Male 225 lb 12/1/2009 Canada
Primary
Concomitant
Intestinal Obstruction Hospitalization 11/11/2009 65 Female 12/8/2009 Consumer Canada
Primary
Concomitant
Swelling 9/16/2009 77 Female 146 lb 10/30/2009 Consumer United States
Primary
Concomitant
Toe Operation Other Serious 9/1/2009 Female 150 lb 1/28/2010 Physician Canada
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 11/11/2009 65 Female 1/25/2010 Physician Canada
Primary
Concomitant
Oral Disorder 9/1/2009 59 Female 115 lb 2/22/2010 Consumer United States
Primary
Concomitant
Malignant Muscle Neoplasm Other Serious 3/19/2009 Male 291 lb 3/5/2010 Physician Canada
Primary
Concomitant
Skin Laceration Other Serious 1/1/2009 Male 170 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Malignant Muscle Neoplasm Other Serious 3/19/2009 Male 291 lb 3/24/2010 Physician Canada
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 82 Female 121 lb 4/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 80 Female 4/27/2010 Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2008 55 Female 208 lb 5/6/2010 United States
Primary
Concomitant
Eye Haemorrhage Other Serious 3/1/2010 64 Male 154 lb 5/14/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Skin Burning Sensation 3/5/2010 70 Male 190 lb 5/17/2010 Physician
Primary
Concomitant
Vertigo Positional Hospitalization 1/1/2001 60 Female 6/10/2010 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis Other Serious 12/3/2007 57 Female 7/6/2010 Physician Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/25/2010 52 Male 274 lb 7/7/2010 Other Health Professional Canada
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/3/2007 57 Female 7/9/2010 Physician Canada
Primary
Concomitant
Oedema Peripheral Other Serious Female 167 lb 7/22/2010 Consumer United States
Primary
Concomitant
Splinter Other Serious 1/1/2009 51 Female 8/17/2010 Consumer United States
Primary
Concomitant
Flushing 9/1/2009 76 Male 210 lb 8/28/2010 United States
Primary
Concomitant
Drug Level Increased Hospitalization 8/1/2010 52 Male 250 lb 10/8/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 10/15/2010 United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/3/2007 57 Female 10/27/2010 Physician Canada
Primary
Concomitant
Diabetes Mellitus Other Serious Male 289 lb 10/29/2010 Other Health Professional Canada
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 11/11/2010 Physician Canada
Primary
Concomitant
Osteoporosis Other Serious 61 Female 11/22/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 9/11/2009 11/30/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 11/20/2010 61 Female 117 lb 12/30/2010 Other Health Professional Canada
Primary
Concomitant
Infection Other Serious 1/1/2009 72 Male 1/29/2011 Consumer United States
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 2/4/2011 Physician Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 12/3/2007 57 Female 2/21/2011 Consumer Canada
Primary
Concomitant
Bladder Cancer Hospitalization 10/29/2010 70 Male 169 lb 4/15/2011 Physician Canada
Primary
Concomitant
Thrombosis Hospitalization 4/1/2011 66 Female 195 lb 4/27/2011 Consumer United States
Primary
Concomitant
Diverticular Perforation Death 6/8/2006 60 Female 266 lb 5/3/2011 Physician United States
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 8/12/2008 80 Male 138 lb 5/23/2011 Physician Canada
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 2/4/2011 42 Female 5/26/2011 Other Health Professional United States
Primary
Concomitant
Bladder Cancer Hospitalization 10/29/2010 70 Male 169 lb 6/3/2011 Physician Canada
Primary
Concomitant
Tongue Haemorrhage Other Serious 5/1/2011 65 Male 206 lb 6/30/2011 Other Health Professional Canada
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 7/8/2011 Physician Canada
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/7/2004 49 Male 7/12/2011 Lawyer United States
Primary
Concomitant
Stress Other Serious 10/12/2004 54 Male 203 lb 7/15/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Hospitalization 10/12/2004 54 Male 203 lb 8/3/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 10/12/2004 54 Male 203 lb 8/24/2011 Lawyer United States
Primary
Concomitant
Cellulitis Hospitalization 7/30/2011 50 Male 269 lb 8/25/2011 Physician United States
Primary
Concomitant
Atrial Fibrillation Other Serious 8/14/2011 63 Male 165 lb 8/31/2011 Physician
Primary
Concomitant
Arteriosclerosis Hospitalization 8/14/2011 63 Male 165 lb 9/1/2011 Physician Canada
Primary
Concomitant
Dyspnoea Other Serious 8/1/2011 57 Female 240 lb 9/12/2011 Consumer Canada
Primary
Concomitant
Haemoglobin Decreased Other Serious 8/1/2011 57 Female 240 lb 9/14/2011 Physician Canada
Primary
Concomitant
Osteochondroma Other Serious Male 291 lb 9/15/2011 Physician Canada
Primary
Concomitant
Pain In Extremity Congenital Anomaly 1/1/2001 60 Female 9/16/2011 Other Health Professional United States
Primary
Concomitant
Haemolytic Anaemia Other Serious 8/1/2011 57 Female 240 lb 9/23/2011 Consumer Canada
Primary
Concomitant
Splenomegaly Hospitalization 6/25/2005 55 Female 10/13/2011 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/16/2011 57 Female 240 lb 10/18/2011 Physician Canada
Primary
Concomitant

Drug Data