Methotrexate combined with Morphine Sulfate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Carpal Tunnel Syndrome Other Serious 12/22/2005 Female 114 lb 1/5/2006 Canada
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2005 44 Female 1/4/2006 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 10/21/2004 Female 176 lb 1/13/2006 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 12/7/2001 73 Female 154 lb 1/20/2006 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 10/15/2004 Female 176 lb 2/10/2006 United Kingdom
Primary
Concomitant
Toe Deformity Other Serious 12/1/2001 Female 286 lb 3/7/2006 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 3/9/2006
Primary
Secondary
Concomitant
Hemiparesis Required Intervention 12/21/2005 63 Male 276 lb 3/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Death 1/1/2005 Female 3/29/2006 Physician United States
Primary
Concomitant
No Adverse Effect Other Serious Female 3/29/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 4/24/2006
Primary
Secondary
Concomitant
Pustular Psoriasis Disability 2/16/2006 48 Female 209 lb 5/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/13/2006 81 Female 5/24/2006 Physician France
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Hospitalization 8/1/2005 52 Female 6/7/2006 Consumer France
Primary
Concomitant
Lung Infection Hospitalization 5/29/2006 76 Female 7/6/2006 Consumer France
Primary
Concomitant
Throat Tightness Other Serious 1/1/2004 Male 270 lb 8/18/2006 Consumer United States
Primary
Concomitant
Hyperaesthesia Other Serious 5/1/2004 57 Female 9/6/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/21/2004 73 Female 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Throat Tightness Other Serious 1/1/2004 Male 270 lb 10/5/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2004 Male 272 lb 10/9/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 6/21/2004 73 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death Female 128 lb 1/22/2007 France
Primary
Concomitant
Infarction Death 11/13/2006 Female 128 lb 2/16/2007 France
Primary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Death Death 4/1/2007 Male 187 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Disease Progression Other Serious Female 117 lb 6/4/2007 Consumer Canada
Primary
Concomitant
Disease Progression Other Serious Female 117 lb 6/22/2007 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 12/25/2004 Female 110 lb 6/25/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Death Male 192 lb 7/18/2007 United Kingdom
Primary
Concomitant
Tooth Loss Hospitalization 6/1/2006 37 Male 7/23/2007 Other Health Professional France
Primary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/20/2007 Consumer United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2005 Male 241 lb 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2005 Male 241 lb 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Life Threatening 7/11/2007 Female 190 lb 11/21/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2007 63 Male 241 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection 9/1/2007 Female 156 lb 12/14/2007 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 12/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/2/2007 Male 219 lb 12/21/2007 Physician United States
Primary
Concomitant
Spinal Compression Fracture Other Serious 7/17/2007 Male 218 lb 12/28/2007 United Kingdom
Primary
Concomitant
Rash Other Serious 8/15/2007 Female 1/2/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/25/2004 Female 110 lb 1/15/2008 Consumer United States
Primary
Concomitant
Hospitalisation Hospitalization 1/1/2008 74 Female 1/22/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 8/15/2007 Female 114 lb 1/22/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 70 Female 1/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
Infarction Hospitalization 11/13/2006 Female 128 lb 2/7/2008 France
Primary
Concomitant
Spinal Compression Fracture Other Serious 7/17/2007 Male 218 lb 2/25/2008 United Kingdom
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Spinal Operation Other Serious 3/21/2008 Female 4/7/2008 Physician United Kingdom
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 11/13/2006 Female 128 lb 4/25/2008 France
Primary
Concomitant
Vitamin D Deficiency 5/1/2008 Female 113 lb 9/12/2008 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 11/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/13/2008 Female 164 lb 11/26/2008 Physician United States
Primary
Concomitant
Pleural Effusion Death 1/1/2003 47 Female 12/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Limb Hospitalization 7/1/2008 Male 12/3/2008 Physician France
Primary
Secondary
Concomitant
Rash Life Threatening 47 Female 121 lb 12/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Visual Impairment 4/1/2008 Female 250 lb 12/12/2008 United States
Primary
Concomitant
Procedural Complication 11/26/2008 Female 198 lb 12/12/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/13/2008 Female 164 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2005 Female 120 lb 1/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 10/1/2007 Female 114 lb 1/23/2009 Physician United States
Primary
Concomitant
Death Other Serious 70 Male 220 lb 1/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Carpal Tunnel Syndrome Other Serious 11/1/2008 Female 125 lb 1/27/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 51 Female 198 lb 2/11/2009 Consumer United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 8/4/2005 Female 121 lb 2/24/2009 Consumer United Kingdom
Primary
Concomitant
Tooth Infection Other Serious 1/1/2008 Female 175 lb 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Meningism Hospitalization 2/13/2009 41 Female 4/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/27/2009 35 Female 345 lb 5/21/2009 Physician United States
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 6/11/2009 Consumer United States
Primary
Concomitant
Muscle Strain 1/1/2009 Male 180 lb 6/12/2009 Physician United States
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Injection Site Extravasation 8/23/2008 Female 130 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vitamin D Deficiency 5/1/2008 Female 113 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Urosepsis Life Threatening 9/21/2009 Male 150 lb 11/10/2009 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/27/2009 35 Female 345 lb 12/1/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Vomiting Other Serious 3 Female 29 lb 1/20/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Death 11/6/2009 Female 163 lb 2/12/2010 United Kingdom
Primary
Concomitant
Pain In Extremity 1/1/2009 Female 185 lb 2/10/2010 Consumer United States
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/29/2009 Male 185 lb 3/15/2010 Physician Poland
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 8/5/2009 Male 185 lb 3/31/2010 Physician Poland
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 5/7/2010 Physician United States
Primary
Concomitant
Sciatica Other Serious 8/31/2009 53 Female 164 lb 5/10/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death 8/11/2009 66 Female 126 lb 5/20/2010 Other Health Professional United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 10/28/2010 Physician United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 9/7/2009 5 Male 38 lb Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2010 53 Male 11/12/2010 Other Health Professional United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 11/29/2010 Physician United States
Primary
Concomitant
Oesophageal Squamous Cell Carcinoma Other Serious 10/18/2010 80 Male 156 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2010 68 Male 12/10/2010 Physician United States
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 4/1/2010 81 Female 127 lb 12/13/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/1/2010 58 Female 144 lb 12/14/2010 Consumer Canada
Primary
Concomitant
Contusion 5/25/2009 12/14/2010 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/1/2010 81 Female 127 lb 12/17/2010 Physician United States
Primary
Concomitant
Weight Increased 2/24/2010 12/19/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2010 58 Female 144 lb 12/22/2010 Consumer Canada
Primary
Secondary
Concomitant
Tooth Infection 12/22/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2010 58 Female 144 lb 12/27/2010 Consumer Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2010 58 Female 144 lb 12/28/2010 Consumer Canada
Primary
Secondary
Concomitant
Cholestasis Hospitalization 5/1/2008 14 Male 205 lb 1/11/2011 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/7/2011 31 Female 139 lb 2/11/2011 Pharmacist United States
Primary
Concomitant
Hemiparesis Hospitalization 4/9/2009 47 Female 152 lb 3/11/2011 Physician Canada
Primary
Secondary
Concomitant
Angioedema Hospitalization 8 Male 3/1/2011 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Death 72 Female 174 lb 3/9/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 2 Female 31 lb 3/11/2011 Pharmacist Canada
Primary
Concomitant
Tenderness Hospitalization 4/22/2011 20 Female 188 lb 4/27/2011 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 12/17/2010 67 Female 4/26/2011 Physician Australia
Primary
Concomitant
Blood Pressure Increased Other Serious 1/1/2010 51 Male 325 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious Female 115 lb 5/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 7/31/2010 Male 210 lb 5/24/2011 Physician Canada
Primary
Secondary
Concomitant
Alopecia 47 Male 179 lb 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Alveolitis Hospitalization 1/1/2010 73 Female 5/31/2011 Consumer France
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 2/18/2002 51 Female 130 lb 6/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 4/25/2008 57 Female 79 lb 6/4/2011 Physician Japan
Primary
Concomitant
Malaise Other Serious 5/2/2005 49 Female 6/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tetany Hospitalization 4/30/2011 33 Female 7/12/2011 Physician Germany
Primary
Secondary
Concomitant
Tetany Hospitalization 4/30/2011 33 Female 7/12/2011 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 2/18/2002 51 Female 130 lb 7/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 4/25/2008 57 Female 79 lb 8/2/2011 Physician Japan
Primary
Concomitant
Hypoglycaemia Other Serious 2/18/2002 51 Female 130 lb 8/4/2011 United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 10/10/2010 20 Male 148 lb 8/24/2011 Consumer France
Primary
Secondary
Concomitant
Dental Alveolar Anomaly Hospitalization Female 8/26/2011 Physician France
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 5/2/2011 63 Male 254 lb 9/2/2011 Physician New Zealand
Primary
Concomitant
Lung Disorder Other Serious 5/13/2011 62 Male 9/14/2011 Consumer France
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/3/2010 34 Female 137 lb 9/16/2011 Physician Denmark
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 8/29/2011 41 Female 227 lb 9/27/2011 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 8/25/2011 41 Female 227 lb 10/3/2011 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 8/25/2011 41 Female 227 lb 10/5/2011 Physician United States
Primary
Concomitant
Cervix Carcinoma Other Serious 9/8/2011 38 Female 111 lb 10/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhoids Other Serious 10/31/2007 35 Female 116 lb 10/19/2011 Consumer United States
Primary
Concomitant
Injection Site Discomfort 11/3/2010 48 Female 326 lb 10/27/2011 Consumer United States
Primary
Concomitant
Myalgia 7/30/2011 52 Female 177 lb 11/7/2011 Pharmacist United States
Primary
Concomitant
Dyspnoea Other Serious 10/1/2010 62 Female 251 lb 11/9/2011 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Disability 10/28/2011 79 Female 136 lb 11/14/2011 Other Health Professional
Primary
Concomitant
Upper Respiratory Tract Infection Female 11/17/2011 Consumer United States
Primary
Concomitant
Cough Hospitalization 1/1/2011 52 Female 190 lb 11/18/2011 Physician United States
Primary
Concomitant
Osteonecrosis Disability 10/28/2011 79 Female 11/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Disability 10/28/2011 79 Female 136 lb 11/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 10/28/2011 79 Female 136 lb 11/17/2011 Other Health Professional
Primary
Concomitant
Drug Ineffective Other Serious Female 200 lb 11/23/2011 Consumer Canada
Primary
Secondary
Concomitant

Drug Data