Methotrexate combined with Neupogen

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Hospitalization 11/12/2004 61 Male 181 lb 1/18/2006 Consumer United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 8/4/2005 Female 1/20/2006 Other Health Professional Sweden
Primary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 3/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Trichosporon Infection Other Serious 1/1/2004 30 Male 3/9/2006 Japan
Primary
Concomitant
Trichosporon Infection Other Serious 1/1/2004 30 Male 3/29/2006 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/7/2006 40 Female 209 lb 3/28/2006 Physician France
Primary
Secondary
Concomitant
Visual Acuity Reduced Required Intervention 6/20/2005 18 Female 4/5/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Hospitalization 54 Male 4/5/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/7/2006 40 Female 209 lb 4/14/2006 Physician France
Primary
Secondary
Concomitant
Visual Acuity Reduced Required Intervention 6/20/2005 18 Female 4/17/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Life Threatening 3/27/2006 Female 116 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Death 8/3/2005 43 Male 4/28/2006 Physician Japan
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/6/2006 United States
Primary
Secondary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 5/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Septic Shock Life Threatening 2/7/2006 40 Female 209 lb 5/15/2006 Physician France
Primary
Secondary
Concomitant
Toothache Other Serious 63 Female 132 lb 5/24/2006 Portugal
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/31/2006 United States
Primary
Secondary
Concomitant
Toothache Other Serious 8/1/2005 63 Female 132 lb 6/8/2006 Portugal
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 16 Male 6/6/2006 Physician United States
Primary
Concomitant
Tri-iodothyronine Free Increased Other Serious 42 Male 6/16/2006 Physician Japan
Primary
Concomitant
Thyroxine Free Increased Other Serious 32 Female 6/16/2006 Other Health Professional Japan
Primary
Concomitant
Toxic Induced Encephalopathy Life Threatening 8/3/2005 43 Male 6/8/2006 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 7/2/2006 Male 9 lb 7/5/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/3/2003 35 Female 8/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2005 72 Male 9/1/2006 United States
Primary
Concomitant
Renal Impairment Other Serious 35 Male 9/5/2006 Japan
Primary
Secondary
Concomitant
Septic Shock Death 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Gastric Haemorrhage Life Threatening 8/30/2006 63 Male 9/26/2006 Physician France
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/9/2005 Male 164 lb 10/5/2006 Physician Australia
Primary
Concomitant
Stomatitis Other Serious 7/1/2006 Female 165 lb 10/9/2006 Physician Belgium
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Required Intervention 9/1/2006 18 Female 10/4/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 9/1/2005 Male 176 lb 11/2/2006 Physician Japan
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 12/7/2006 Physician Australia
Primary
Secondary
Stomatitis Other Serious 7/12/2006 Female 165 lb 12/12/2006 Physician Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 55 Female 12/18/2006 Consumer Hong Kong
Primary
Secondary
Concomitant
Vaginal Inflammation Other Serious 55 Female 12/18/2006
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/4/2005 29 Male 141 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 1/23/2007 United States
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 9/15/2005 36 Male 176 lb 1/15/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 9/15/2005 36 Male 176 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 9/13/2005 36 Male 176 lb 1/30/2007 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Life Threatening 8/30/2006 63 Male 1/31/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vasculitis Death 15 Male 2/6/2007 Physician Canada
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/1/2004 49 Male 2/8/2007 Japan
Primary
Concomitant
Vasculitis Death 15 Male 2/12/2007 Physician Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2004 49 Male 2/10/2007 Japan
Primary
Concomitant
Pneumonia Hospitalization 1/3/2007 53 Male 179 lb 2/12/2007 Physician Israel
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 70 Female 2/12/2007 Consumer Israel
Primary
Secondary
Concomitant
Skin Lesion Other Serious 0 Male 2/15/2007 Other Health Professional Turkey
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 2/20/2007 Consumer Australia
Primary
Secondary
Thrombocytopenia Other Serious 2/20/2007 Consumer Australia
Primary
Secondary
Vomiting Hospitalization 7/4/2005 29 Male 141 lb 2/5/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 11/12/2001 23 Female 2/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/12/2001 23 Female 2/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/12/2001 23 Female 86 lb 2/23/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/12/2001 23 Female 2/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 54 Male 3/15/2007 Japan
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 3/17/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 1/23/2007 59 Female 150 lb 3/18/2007 Physician France
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/23/2006 Female 163 lb 4/4/2007 Physician Bahrain
Primary
Concomitant
Thrombocytopenia Death 13 Female 4/16/2007 Other Health Professional India
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 54 Male 4/17/2007 Japan
Primary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 4/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2006 54 Female 4/19/2007 Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/7/2007 38 Female 189 lb 5/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/7/2007 38 Female 189 lb 5/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Transplant Rejection Death 5/16/2006 49 Female 109 lb 4/29/2007 Physician Japan
Primary
Concomitant
Pneumonia Cytomegaloviral Other Serious 65 Female 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Hesitation Other Serious 42 Female 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 19 Female 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 22 Male 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neurotoxicity Death 54 Male 5/25/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2006 54 Female 6/11/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2003 31 Male 6/23/2007 Japan
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/7/2007 39 Male 6/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 7/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/7/2007 39 Male 7/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Life Threatening 12/6/2006 50 Female 7/16/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/18/2007 Female 141 lb 7/20/2007 United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/7/2007 39 Male 8/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Life Threatening 5/6/2007 56 Female 9/18/2007 Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 3/21/2007 20 Male 9/18/2007 Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 1/24/2007 21 Male 9/18/2007 Japan
Primary
Concomitant
Transplant Rejection Life Threatening 5/23/2007 60 Male 9/20/2007 Other Health Professional Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 8/10/2007 30 Female 9/20/2007 Other Health Professional Japan
Primary
Concomitant
Rash 2/1/2007 Female 9/27/2007 Physician United States
Primary
Concomitant
Stomatitis 8/31/2006 Female 9/27/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 21 Female 8/16/2007 Physician United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 54 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 61 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 79 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/12/2007 70 Male 196 lb 10/1/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/7/2007 39 Male 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Fibrosis Other Serious 5/7/2007 39 Male 10/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 10/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 10/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 30 Female 10/18/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/28/2007 34 Female 10/22/2007 Japan
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 4/13/2007 49 Male 10/22/2007 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/6/2006 50 Female 10/22/2007 Japan
Primary
Secondary
Concomitant
Reticulocyte Count Decreased Other Serious 54 Male 10/25/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 10/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease 7/30/2007 51 Male 10/26/2007 Japan
Primary
Concomitant
Stomatitis 6/10/2007 21 Female 10/26/2007 Japan
Primary
Concomitant
Vasculitis Other Serious 15 Male 11/5/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 28 Female 11/9/2007 Japan
Primary
Concomitant
Pseudomonal Sepsis Hospitalization 76 Male 11/13/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9 Male 11/14/2007
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Streptococcal Sepsis Other Serious 4/6/2007 21 Male 11/16/2007 Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2007 4 Male 11/16/2007 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/19/2007 18 Female 11/16/2007 Japan
Primary
Concomitant
Vomiting Hospitalization 6/3/2007 60 Male 11/16/2007 Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 5/2/2007 25 Male 11/16/2007 Japan
Primary
Concomitant
Streptococcal Sepsis Other Serious 5/3/2007 54 Female 11/16/2007 Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 10/1/2005 28 Female 11/23/2007 Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 69 Female 11/27/2007 Pharmacist United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 9/12/2007 72 Female 12/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Skin Exfoliation 11/1/2007 Female 2/11/2008 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/1/2008 73 Male 2/20/2008 Consumer France
Primary
Secondary
Weight Increased Hospitalization 6/13/2006 74 Male 198 lb 3/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Rash Other Serious 56 Male 3/9/2008 Japan
Primary
Secondary
Concomitant
Rash Other Serious 12/1/2006 56 Male 3/11/2008 Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/19/2008 71 Female 148 lb 3/12/2008 Physician France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/18/2008 Female 167 lb 3/6/2008 United States
Primary
Secondary
Pneumonia Fungal Life Threatening 3/25/2008 India
Primary
Secondary
Concomitant
Pneumonia Fungal Life Threatening 3/26/2008 India
Primary
Secondary
Concomitant
Skin Injury Hospitalization 3/6/2008 49 Male 277 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 4/4/2008 Physician Germany
Primary
Concomitant
Stem Cell Transplant Other Serious 4/4/2008 France
Primary
Secondary
Sepsis Other Serious 4/4/2008 Other Health Professional France
Primary
Secondary
Therapeutic Response Decreased Other Serious 4/4/2008 Other Health Professional France
Primary
Secondary
Weight Increased Other Serious 6/13/2006 74 Male 198 lb 4/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 3/29/2007 69 Female 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/1/2008 73 Male 4/28/2008 Consumer France
Primary
Secondary
Intestinal Haemorrhage Hospitalization 3/14/2008 5/6/2008 Physician Italy
Primary
Secondary
Stomatitis Life Threatening 10/31/2007 50 Male 4/30/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 10/26/2007 65 Female 4/30/2008 Japan
Primary
Concomitant

Drug Data