Amlodipine Besylate combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Subcutaneous Haematoma Hospitalization 11/25/2005 Male 1/26/2006 Physician Japan
Primary
Concomitant
Weight Increased Life Threatening 4/22/2005 Male 254 lb 2/13/2006 United States
Primary
Concomitant
Blood Pressure Decreased Death 2/13/2005 64 Male 223 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 12/1/2005 Female 142 lb 3/16/2006 Consumer Canada
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 11/18/2005 Male 4/6/2006 Physician Japan
Primary
Concomitant
Injection Site Induration Hospitalization 11/1/2005 Female 130 lb 4/25/2006 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 10/31/2004 67 Female 124 lb 3/2/2006 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 11/20/2003 66 Male 209 lb 5/18/2006 Lawyer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 10/26/2005 56 Female 248 lb 12/29/2005 Physician United States
Primary
Concomitant
Prostate Examination Abnormal Hospitalization Male 158 lb 5/24/2006 Consumer United States
Primary
Concomitant
Cardiomyopathy Life Threatening 4/22/2005 Male 254 lb 6/16/2006 United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 8/1/2005 52 Female 6/7/2006 Consumer France
Primary
Concomitant
Oral Mucosal Blistering Other Serious 8/2/2006 43 Female 211 lb 8/15/2006 United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/15/2006 Female 198 lb 8/28/2006 Physician Italy
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/15/2006 Female 198 lb 9/6/2006 Physician Italy
Primary
Concomitant
Prostate Examination Abnormal Hospitalization Male 158 lb 9/7/2006 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 5/10/2006 Male 9/21/2006 Other Health Professional Belgium
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/15/2006 Female 198 lb 9/29/2006 Physician Italy
Primary
Concomitant
Small Intestinal Obstruction Death Male 143 lb 9/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cystitis Noninfective Hospitalization 3/17/2006 73 Female 10/12/2006 Physician Belgium
Primary
Concomitant
Scar Other Serious 8/1/2006 Female 10/16/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/15/2006 Female 198 lb 12/1/2006 Physician Italy
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/26/2005 Female 168 lb 12/13/2006 Greece
Primary
Concomitant
Spinal Fracture Life Threatening 3/1/2005 Female 154 lb 1/25/2007 Belgium
Primary
Concomitant
Spinal Fracture Hospitalization 5/19/2006 Female 2/9/2007 Physician Belgium
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 5/19/2006 Female 2/19/2007 Physician Belgium
Primary
Concomitant
Skin Laceration Hospitalization 12/9/2005 Male 128 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious Male 206 lb 3/22/2007 Consumer Canada
Primary
Concomitant
Rhabdomyolysis Hospitalization 83 Male 4/9/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 83 Male 225 lb 4/13/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/15/2007 Male 205 lb 4/19/2007 Consumer Canada
Primary
Concomitant
Dyspnoea Other Serious Male 206 lb 4/20/2007 Physician Canada
Primary
Concomitant
Delirium Other Serious 3/13/2007 70 Male 169 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2005 82 Male 225 lb 5/7/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2005 82 Male 225 lb 5/9/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2005 82 Male 225 lb 5/14/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 12/1/2006 Female 117 lb 6/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Injury Hospitalization 10/1/2006 53 Female 155 lb 6/6/2007 Other Health Professional Japan
Primary
Concomitant
Spinal Fracture Life Threatening 3/1/2005 Female 154 lb 7/13/2007 Belgium
Primary
Concomitant
Tumour Invasion Other Serious 5/1/2007 Female 11/16/2007 Belgium
Primary
Concomitant
Pustular Psoriasis 12/1/2006 Female 12/11/2007 Physician United States
Primary
Secondary
Concomitant
Injection Site Reaction 10/16/2007 Male 240 lb 12/14/2007 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/19/2007 Female 117 lb 1/24/2008 United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 1/1/2008 61 Male 2/22/2008 United Kingdom
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 6/1/2007 59 Female 3/6/2008 Consumer Australia
Primary
Concomitant
Pyrexia 10/10/2006 Male 195 lb 3/14/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious Female 5/1/2008 Consumer United States
Primary
Concomitant
Ulcer Other Serious 1/31/2008 44 Female 169 lb 5/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Mass Hospitalization 8/7/2006 Male 160 lb 6/13/2008 Japan
Primary
Concomitant
Pulmonary Mass Hospitalization 8/7/2006 Male 160 lb 6/27/2008 Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 10/19/2004 Male 161 lb 6/30/2008 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Mass Hospitalization 8/7/2006 Male 160 lb 7/11/2008 Japan
Primary
Concomitant
Ulcer Other Serious 1/31/2008 44 Female 169 lb 7/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 1/1/2004 61 Male 8/6/2008 Physician Switzerland
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 160 lb 8/8/2008 Japan
Primary
Concomitant
Death Death 6/16/2008 88 Female 8/27/2008 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 160 lb 9/12/2008 Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2005 Female 120 lb 9/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Female 9/12/2008 Consumer United States
Primary
Concomitant
Death Other Serious 6/16/2008 88 Female 9/15/2008 Physician Japan
Primary
Secondary
Concomitant
Lymphocytic Leukaemia Hospitalization 3/10/2008 Male 9/18/2008 France
Primary
Concomitant
Lymphoma Hospitalization 8/27/2007 Female 137 lb 9/19/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Death 6/16/2008 Female 9/26/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/31/2008 44 Female 169 lb 9/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 160 lb 10/1/2008 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 167 lb 11/26/2008 Japan
Primary
Concomitant
Osteolysis Hospitalization 3/14/2008 82 Female 12/8/2008 Other Health Professional Italy
Primary
Concomitant
Rash Hospitalization 11/13/2008 Female 151 lb 12/9/2008 Japan
Primary
Concomitant
Pneumoperitoneum Hospitalization 8/30/2004 72 Female 12/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Osteolysis Hospitalization 3/14/2008 82 Female 12/26/2008 Other Health Professional Italy
Primary
Concomitant
Acute Myocardial Infarction Death 12/15/2008 Female 115 lb 1/13/2009 Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2005 Female 120 lb 1/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2007 Female 1/22/2009 Physician Brazil
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 11/13/2008 Female 151 lb 2/5/2009 Japan
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 2/26/2009 United States
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 3/10/2009 United States
Primary
Concomitant
Hypersensitivity Hospitalization 11/13/2008 Female 151 lb 3/11/2009 Japan
Primary
Concomitant
Acute Myocardial Infarction Death 12/15/2008 Female 115 lb 3/16/2009 Japan
Primary
Concomitant
Toe Operation Hospitalization 1/1/2006 Female 4/3/2009 Consumer United Kingdom
Primary
Secondary
Nasopharyngitis Hospitalization 12/1/2008 Female 4/3/2009 Physician United Kingdom
Primary
Concomitant
Ischaemic Stroke Life Threatening 2/1/2009 Male 4/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 11/30/2008 Male 4/10/2009 Physician Germany
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Hospitalization 2/21/2008 Male 148 lb 5/7/2009 France
Primary
Concomitant
Tonsillitis 12/6/2008 Female 106 lb 6/12/2009 Japan
Primary
Concomitant
Tooth Fracture Other Serious 9/28/2005 68 Female 123 lb 4/20/2009 Physician United States
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 12/6/2008 Female 106 lb 7/16/2009 Japan
Primary
Concomitant
Tonsillitis Hospitalization 12/6/2008 Female 106 lb 8/6/2009 Japan
Primary
Concomitant
Pyelonephritis Hospitalization 2/25/2009 Female 81 lb 8/21/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 7/16/2009 Female 110 lb 9/1/2009 Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/9/2009 Female 9/2/2009 Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/16/2009 Female 110 lb 9/3/2009 Japan
Primary
Concomitant
Pneumonia Hospitalization 2/12/2009 Female 123 lb 9/10/2009 Japan
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 1/1/2004 61 Male 9/11/2009 Physician Switzerland
Primary
Secondary
Concomitant
Incorrect Dose Administered 3/13/2007 Female 231 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 4/10/2007 Female 130 lb 9/11/2009 Consumer United States
Primary
Concomitant
Pyelonephritis Hospitalization 2/25/2009 Female 81 lb 9/24/2009 Japan
Primary
Concomitant
Haemophilus Infection Hospitalization 2/12/2009 Female 123 lb 10/8/2009 Japan
Primary
Secondary
Concomitant
Haemophilus Infection Hospitalization 2/12/2009 Female 123 lb 10/19/2009 Japan
Primary
Secondary
Concomitant
Vitamin D Decreased Hospitalization 8/11/2008 48 Female 212 lb 11/11/2009 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Death 12/15/2008 Female 115 lb 12/9/2009 Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 2/27/2009 Female 12/11/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 11/10/2009 Male 128 lb 1/5/2010 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 12/11/2009 Female 139 lb 1/12/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/23/2009 Female 188 lb 1/30/2010 United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 12/11/2009 Female 139 lb 2/24/2010 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 12/11/2009 Female 139 lb 2/24/2010 Physician Japan
Primary
Secondary
Concomitant
Vitamin D Decreased Hospitalization 8/11/2008 48 Female 212 lb 2/26/2010 Physician United States
Primary
Concomitant
Hyponatraemia Hospitalization 12/11/2009 Female 139 lb 3/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 11/10/2009 Male 128 lb 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/12/2010 Female 112 lb 3/2/2010 Korea, Republic Of
Primary
Concomitant
Spinal Column Stenosis Hospitalization 7/9/2009 67 Female 3/18/2010 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 1/7/2010 Female 3/26/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 2/15/2010 Female 225 lb 3/30/2010 Physician Australia
Primary
Concomitant
Renal Disorder Other Serious 2/15/2010 72 Female 225 lb 4/1/2010 Physician Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/15/2010 63 Female 254 lb 4/2/2010 Other Health Professional Canada
Primary
Concomitant
Right Ventricular Failure Hospitalization 10/1/2009 74 Female 4/12/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 3/29/2010 52 Male 4/12/2010 Physician France
Primary
Secondary
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 4/21/2010 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 4/27/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Traumatic Lung Injury Other Serious 10/1/2009 64 Female 137 lb 5/7/2010 Brazil
Primary
Concomitant
Traumatic Lung Injury Other Serious 10/1/2009 64 Female 137 lb 5/10/2010 Brazil
Primary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 5/13/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 5/28/2010 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 3/1/2010 57 Female 142 lb 6/3/2010 Pharmacist Japan
Primary
Concomitant
Weight Increased Other Serious 10/27/2009 70 Female 154 lb 6/3/2010 Consumer United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2010 61 Female 5/28/2010 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 6/10/2010 Physician Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2010 61 Female 6/9/2010 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 6/17/2010 Physician Japan
Primary
Secondary
Concomitant
Pyothorax Hospitalization 3/1/2010 57 Female 142 lb 6/21/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 4/7/2010 61 Female 7/1/2010 Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2010 61 Female 7/1/2010 Japan
Primary
Secondary
Concomitant
Pyothorax Hospitalization 3/3/2010 57 Female 142 lb 7/15/2010 Physician Japan
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 9/28/2005 68 Female 123 lb 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 9/28/2005 68 Female 123 lb 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 4/7/2010 61 Female 7/13/2010 Japan
Primary
Concomitant
Pain Other Serious 1/1/2009 60 Female 174 lb 7/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Nasopharyngitis Hospitalization 7/5/2010 73 Male 7/20/2010 Japan
Primary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 7/26/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/5/2010 73 Male 7/23/2010 Japan
Primary
Concomitant
Blood Pressure Inadequately Controlled Female 7/31/2010 Pharmacist United States
Primary
Concomitant
Hydrocele Hospitalization 7/20/2010 71 Male 116 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/5/2010 73 Male 7/28/2010 Japan
Primary
Concomitant
Cough Hospitalization 12/29/2009 60 Female 122 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngitis Hospitalization 7/5/2010 73 Male 8/10/2010 Other Health Professional Japan
Primary
Concomitant
Pyothorax Hospitalization 3/3/2010 57 Female 142 lb 8/18/2010 Physician Japan
Primary
Secondary
Concomitant
Immune System Disorder Hospitalization 7/5/2010 73 Male 8/17/2010 Physician Japan
Primary
Concomitant
Immune System Disorder Hospitalization 7/5/2010 73 Male 8/17/2010 Other Health Professional Japan
Primary
Concomitant

Drug Data