Ifosfamide combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neurotoxicity Death 36 Female 1/4/2006 Consumer Japan
Primary
Secondary
Tongue Disorder Other Serious 12/5/2005 Male 216 lb 12/27/2005 United States
Primary
Secondary
Neurotoxicity Death 36 Female 1/5/2006 Physician Turkey
Primary
Secondary
Concomitant
Respiratory Failure Death 7/13/2005 57 Female 159 lb 1/13/2006 Physician Germany
Primary
Concomitant
Leukoencephalopathy Death 36 Female 1/26/2006 Consumer Japan
Primary
Secondary
Swelling Death 36 Female 1/31/2006 Physician Turkey
Primary
Secondary
Swelling Death 36 Female 2/13/2006 Physician Turkey
Primary
Secondary
Therapy Non-responder Death 36 Female 2/14/2006 Physician Turkey
Primary
Secondary
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
T-cell Lymphoma Hospitalization 36 Female 3/17/2006 Physician Turkey
Primary
Secondary
Stupor Death 36 Female 3/24/2006 Turkey
Primary
Secondary
Concomitant
Performance Status Decreased Other Serious 3/13/2006 Male 216 lb 3/29/2006 United States
Primary
Secondary
Thrombocytopenia Other Serious 16 Male 6/6/2006 Physician United States
Primary
Concomitant
Tongue Disorder Hospitalization 6/1/2006 Male 212 lb 7/18/2006 Physician Germany
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 36 Female 7/14/2006 Other Health Professional Turkey
Primary
Secondary
Tachycardia Hospitalization 3/4/2006 Male 311 lb 8/11/2006 United States
Primary
Secondary
Septic Shock Death 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Lung Infection Pseudomonal Other Serious 50 Female 9/29/2006 Canada
Primary
Secondary
Concomitant
Stem Cell Transplant Death Unknown 9/29/2006 France
Primary
Secondary
Concomitant
Neurotoxicity Other Serious Unknown 9/29/2006 France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 16 Female 10/18/2006 Physician France
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 8/31/2006 47 112 lb 10/23/2006 Physician Germany
Primary
Secondary
Thrombocytopenia Other Serious 16 Female 11/27/2006
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/30/2006 Male 254 lb 12/6/2006 United States
Primary
Secondary
Tremor Hospitalization 11/20/2006 Female 216 lb 12/6/2006 United States
Primary
Secondary
Renal Failure Acute Hospitalization 8/12/2006 50 Male 166 lb 2/9/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 16 Female 3/14/2007 Other Health Professional France
Primary
Secondary
Visual Acuity Reduced Life Threatening 16 Female 110 lb 3/15/2007
Primary
Secondary
Stomatitis Life Threatening 1/29/2007 68 Male 159 lb 3/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 16 Female 110 lb 3/21/2007 Other Health Professional France
Primary
Secondary
Stomatitis Life Threatening 1/29/2007 68 Male 3/22/2007 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 31 Male 4/4/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/16/2005 17 Male 4/18/2007 Other Health Professional Malaysia
Primary
Secondary
Staphylococcal Infection Other Serious 45 Male 143 lb 4/13/2007 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious Unknown 4/16/2007 Germany
Primary
Secondary
Thrombocytopenia Other Serious 61 Female 4/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/19/2007 Male 198 lb 5/8/2007 United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 36 Female 5/25/2007 Physician Turkey
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 6/1/2007 Physician Germany
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 6/1/2007 Physician Germany
Primary
Secondary
Tremor Other Serious 58 Male 6/11/2007 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 6/3/2007 Male 188 lb 6/8/2007 United States
Primary
Secondary
Xerosis Hospitalization 11 Male 6/13/2007 Physician United States
Primary
Concomitant
Tumour Necrosis Other Serious 17 Male 6/16/2007 United States
Primary
Secondary
Pancreatitis Acute Other Serious 11/1/2004 9 Male 6/29/2007 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 7/3/2007
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 4/1/2005 13 Male 7/2/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 7/18/2007 Female 141 lb 7/20/2007 United States
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 5 Female 7/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 7/25/2007 Male 187 lb 7/30/2007 United States
Primary
Secondary
Synovial Sarcoma Other Serious 23 Male 9/6/2007 Other Health Professional Japan
Primary
Secondary
Staphylococcal Infection Other Serious 10/2/2006 45 Male 143 lb 8/31/2007 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 8 Female 9/6/2007 Physician China
Primary
Secondary
Concomitant
Synovial Sarcoma Other Serious 9/1/1994 23 Male 9/13/2007 Consumer United States
Primary
Secondary
Myelodysplastic Syndrome Death 23 Male 9/7/2007 Physician United Kingdom
Primary
Secondary
Hormone Level Abnormal Other Serious 9/14/2007 Consumer United States
Primary
Secondary
Synovial Sarcoma Other Serious 9/1/1994 23 Male 9/14/2007
Primary
Secondary
Acute Myeloid Leukaemia Death 5 Female 9/12/2007 Physician Brazil
Primary
Secondary
Synovial Sarcoma Other Serious 9/1/1994 23 Male 9/17/2007 Consumer United States
Primary
Secondary
Thrombocytopenia Other Serious 20 Male 9/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Synovial Sarcoma Other Serious 9/1/1994 23 Male 9/20/2007 Japan
Primary
Secondary
Hepatitis B Death 54 Male 9/25/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 21 Female 8/16/2007 Physician United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 14 Female 10/2/2007 Other Health Professional United States
Primary
Secondary
Interacting
Vomiting Other Serious 14 Female 10/2/2007
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 6/1/2006 Male 212 lb 10/5/2007 Physician Germany
Primary
Secondary
Concomitant
Procedural Site Reaction Other Serious 20 Male 10/23/2007 Physician United States
Primary
Concomitant
Hepatitis B Death 54 Male 10/31/2007 Physician Japan
Primary
Concomitant
Venous Thrombosis Hospitalization 11 Male 10/30/2007 Physician United States
Primary
Concomitant
Hepatitis B Death 54 Male 11/8/2007 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 20 Male 11/14/2007
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 32 Female 11/21/2007 Other Health Professional Germany
Primary
Secondary
Toxic Encephalopathy Other Serious 32 Female 11/28/2007 Other Health Professional Germany
Primary
Secondary
Staphylococcal Infection Hospitalization 11/25/2006 24 Male 95 lb 11/20/2007 Physician Japan
Primary
Concomitant
Toxic Encephalopathy Other Serious 32 Female 12/3/2007 Consumer United States
Primary
Secondary
Grand Mal Convulsion Death 32 Female 12/3/2007
Primary
Secondary
Concomitant
Vomiting Other Serious 11/11/2007 Male 289 lb 12/4/2007 United States
Primary
Secondary
Tachycardia Hospitalization 12/21/2007 Male 289 lb 1/7/2008 United States
Primary
Secondary
Refusal Of Treatment By Relative Other Serious 6 Male 1/22/2008 Physician Turkey
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 6 Male 1/30/2008 Other Health Professional Turkey
Primary
Secondary
Loss Of Consciousness Other Serious 6 Male 2/7/2008 Turkey
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/16/2008 35 Male 157 lb 2/8/2008 Physician France
Primary
Secondary
Neutropenia Hospitalization 2/6/2008 Female 2/19/2008 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Death 76 Female 98 lb 2/21/2008 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 6 Male 2/21/2008 Turkey
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 6/16/2006 43 Male 2/15/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 2/7/2008 Male 190 lb 2/12/2008 United States
Primary
Secondary
Encephalopathy Death 6 Male 2/27/2008 United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/13/2008 35 Male 157 lb 2/20/2008 Physician France
Primary
Secondary
Encephalopathy Death 6 Male 2/29/2008 Other Health Professional United States
Primary
Secondary
Encephalopathy Death 6 Male 2/29/2008 United States
Primary
Secondary
Treatment Noncompliance Hospitalization 2/19/2008 Male 187 lb 2/28/2008 United States
Primary
Secondary
Encephalopathy Death 6 Male 3/8/2008 United States
Primary
Concomitant
Vision Blurred Death 6 Male 3/1/2008 United States
Primary
Secondary
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Death 6 Male 3/10/2008
Primary
Secondary
Concomitant
Encephalopathy Death 6 Male 3/13/2008 United States
Primary
Secondary
Vomiting Other Serious 6 Male 3/15/2008 Physician United States
Primary
Secondary
Concomitant
Viral Diarrhoea Death 6 Male 3/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Effusion Death 1/1/2008 6 Male 3/28/2008 United States
Primary
Secondary
Ewing's Sarcoma Other Serious 16 Male 3/31/2008
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Systemic Inflammatory Response Syndrome Disability 78 Female 159 lb 4/7/2008 United Kingdom
Primary
Concomitant
Subdural Effusion Other Serious 6 Male 4/16/2008 Consumer United States
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/22/2008 Consumer Japan
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/16/2008 35 Male 5/9/2008 Physician France
Primary
Secondary
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Radiculitis Lumbosacral Hospitalization 11/1/2007 64 Female 122 lb 5/13/2008 Physician Germany
Primary
Concomitant
Refusal Of Treatment By Relative Disability 6 Male 5/19/2008 Physician Turkey
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Premature Ageing Other Serious 42 Male 6/16/2008 Physician Germany
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Premature Ageing Other Serious 42 Male 6/25/2008 Physician Germany
Primary
Concomitant
Premature Ageing Other Serious 42 Male 6/25/2008 Physician Germany
Primary
Concomitant
Pyrexia Life Threatening 6/3/2008 64 Female 6/27/2008 Physician Finland
Primary
Concomitant
Sepsis Other Serious 63 Male 7/3/2008 Consumer Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 39 Male 7/3/2008 Consumer Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 28 Male 7/3/2008 Consumer Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 57 Male 7/3/2008 Consumer Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 33 Male 7/3/2008 Consumer Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Other Serious 11 Female 7/16/2008 Other Health Professional Switzerland
Primary
Secondary
Lung Disorder Hospitalization 7/3/2008 80 Male 168 lb 7/14/2008 Physician France
Primary
Secondary
Concomitant
Neurotoxicity Life Threatening 1/1/2007 37 Male 7/28/2008 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 11 Female 7/17/2008 Other Health Professional Switzerland
Primary
Secondary
Neuropathy Peripheral Other Serious 1/1/2007 37 Male 7/29/2008 India
Primary
Secondary
Concomitant
Malabsorption 7/28/2008 Male 125 lb 7/28/2008 United States
Primary
Secondary
Thrombocytopenia Other Serious 20 Male 7/30/2008 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Other Serious 11 Female 7/26/2008 Israel
Primary
Secondary
Lymphoma Hospitalization 7/3/2008 80 Male 168 lb 8/1/2008 Physician France
Primary
Secondary
Concomitant
Leukocytosis Other Serious 7/1/2000 37 Female 8/7/2008 Physician United Kingdom
Primary
Concomitant
Febrile Neutropenia Other Serious 11 Female 7/31/2008 Switzerland
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/22/2008 9 Male 76 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 6/3/2008 64 Female 8/5/2008 Physician Finland
Primary
Secondary
Concomitant
Death Death 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Fungal Sepsis Death 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Candida Pneumonia Other Serious 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Recurrent Other Serious 42 Male 8/14/2008 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Hospitalization 8/5/2008 Female 136 lb 8/18/2008 United States
Primary
Secondary

Drug Data