Methotrexate combined with Restasis

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Cancer Other Serious 1/1/2005 Female 154 lb 1/3/2006 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 11/1/2002 Female 1/6/2006 Physician United States
Primary
Secondary
Concomitant
Food Poisoning Hospitalization 9/1/2005 Female 4/14/2006 Physician United States
Primary
Concomitant
Histoplasmosis Hospitalization 5/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Injection Site Bruising Male 12/18/2006 Consumer United States
Primary
Concomitant
Fall Hospitalization 11/1/2006 56 Male 1/3/2007 Consumer United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 6/11/2007 Female 200 lb 11/7/2007 Physician United States
Primary
Concomitant
Gastrointestinal Carcinoma Other Serious 67 Female 2/15/2008 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Required Intervention 6/14/2006 78 Female 1/17/2008 Physician United States
Primary
Concomitant
Mass Other Serious 9/1/2006 54 Female 174 lb 3/3/2008 Other Health Professional United States
Primary
Concomitant
Psoriatic Arthropathy 8/1/2007 Female 12/11/2008 Physician United States
Primary
Secondary
Concomitant
Psoriasis 10/1/2008 67 Female 12/31/2008 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 Female 1/5/2009 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 Female 2/13/2009 Consumer United States
Primary
Concomitant
Presyncope Hospitalization 3/1/2009 33 Female 4/13/2009 Physician United States
Primary
Concomitant
Dizziness Other Serious 4/2/2009 Female 130 lb 5/6/2009 Physician United States
Primary
Concomitant
Wheezing Other Serious 3/1/2009 Female 5/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 1/1/2006 Female 177 lb 6/9/2009 Consumer United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/2006 Female 177 lb 6/10/2009 Consumer United States
Primary
Concomitant
Pyrexia 11/10/2008 Female 6/11/2009 United States
Primary
Concomitant
Injection Site Irritation 3/2/2009 Female 170 lb 6/11/2009 Consumer United States
Primary
Concomitant
Renal Cancer Other Serious 1/1/2003 Female 189 lb 7/24/2009 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/17/2006 Female 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/13/2007 Female 231 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/23/2007 Female 211 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Papule 6/16/2009 Female 147 lb 9/19/2009 United States
Primary
Concomitant
Injection Site Swelling 12/18/2008 Female 189 lb 9/19/2009 Consumer United States
Primary
Concomitant
Vasculitis Female 218 lb 9/19/2009 United States
Primary
Concomitant
Pruritus Other Serious 10/26/2009 Female 11/3/2009 United States
Primary
Concomitant
Nasopharyngitis 4/15/2009 Female 181 lb 12/8/2009 Physician United States
Primary
Concomitant
Vitreous Floaters 1/22/2009 Female 1/24/2010 Consumer United States
Primary
Concomitant
Insomnia 49 Female 1/24/2010 Consumer United States
Primary
Concomitant
Tonsillitis 5/1/2009 29 Female 1/24/2010 Consumer United States
Primary
Concomitant
Nasopharyngitis Other Serious 10/15/2009 Female 140 lb 1/30/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 9/3/2006 Female 188 lb 1/30/2010 Consumer United States
Primary
Concomitant
Fatigue 8/27/2008 53 Female 220 lb 2/22/2010 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Hospitalization 2/24/2010 Female 235 lb 3/25/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/24/2009 53 Female 160 lb 4/16/2010 Physician United States
Primary
Concomitant
Swelling Face Hospitalization 2/24/2010 66 Female 235 lb 4/19/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 11/1/2008 55 Female 208 lb 5/6/2010 United States
Primary
Concomitant
Eye Discharge 1/12/2010 44 Female 5/6/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death 8/11/2009 66 Female 126 lb 5/20/2010 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/1/2009 59 Female 7/8/2010 Physician United States
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 5/19/2010 60 Male 181 lb 8/26/2010 Consumer United States
Primary
Secondary
Concomitant
Pelvic Fluid Collection Other Serious 8/7/2010 63 Female 10/11/2010 Consumer United States
Primary
Concomitant
Tongue Biting 71 Male 10/13/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 10/1/2010 61 Female 160 lb 11/6/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 12/1/2009 73 Female 152 lb 12/10/2010 Physician United States
Primary
Secondary
Concomitant
Hip Fracture Other Serious 8/7/2010 63 Female 12/15/2010 Physician United States
Primary
Concomitant
Pelvic Fracture Other Serious Female 12/17/2010 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Female 1/17/2011 Consumer United States
Primary
Concomitant
Lip Dry 3/8/2010 66 Female 225 lb 1/28/2011 United States
Primary
Secondary
Concomitant
Influenza Like Illness 1/1/2010 52 Female 262 lb 1/29/2011 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 5/5/2010 60 Female 1/29/2011 United States
Primary
Concomitant
Sinusitis 5/1/2010 68 Female 1/29/2011 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 3/1/2010 Female 1/29/2011 Consumer United States
Primary
Concomitant
Sinus Disorder 6/16/2010 19 Female 1/29/2011 Consumer United States
Primary
Concomitant
Back Pain 9/15/2010 69 Female 185 lb 1/30/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Female 125 lb 1/30/2011 Consumer United States
Primary
Concomitant
Delirium Hospitalization Female 2/3/2011 Physician United States
Primary
Concomitant
Oropharyngeal Pain Hospitalization 8/5/2010 54 Female 140 lb 1/29/2011 United States
Primary
Concomitant
Gastrooesophageal Cancer Death 10/1/2010 71 Male 2/14/2011 Physician United States
Primary
Concomitant
Adverse Event Hospitalization 5/19/2010 60 Male 181 lb 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Death Other Serious 1/22/2011 76 Female 2/28/2011 Physician United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 5/19/2010 60 Male 181 lb 3/4/2011 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral 1/1/2010 61 Female 160 lb 2/7/2011 Consumer United States
Primary
Concomitant
Middle Insomnia 1/1/2010 75 Female 4/22/2011 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 58 Female 179 lb 4/22/2011 Consumer United States
Primary
Secondary
Concomitant
Anxiety Death Female 116 lb 4/20/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 11/28/2010 62 Female 160 lb 2/7/2011 Consumer United States
Primary
Concomitant
Hip Fracture Hospitalization 8/7/2010 63 Female 4/29/2011 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization Female 116 lb 5/10/2011 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 9/23/2009 60 Female 5/9/2011 Consumer United States
Primary
Concomitant
Cognitive Disorder Hospitalization Female 116 lb 5/23/2011 Consumer United States
Primary
Concomitant
Abdominal Discomfort 2/1/2011 40 Male 165 lb 6/9/2011 Consumer United States
Primary
Concomitant
Ear Infection 11/28/2010 62 Female 160 lb 5/12/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/16/2011 72 Female 185 lb 6/8/2011 Other Health Professional United States
Primary
Concomitant
Amyotrophic Lateral Sclerosis Hospitalization 5/16/2011 72 Female 185 lb 6/20/2011 Other Health Professional United States
Primary
Concomitant
Accidental Overdose Death 48 Female 247 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Hot Flush Other Serious Female 137 lb 9/7/2011 Lawyer United States
Primary
Concomitant
Drug Abuse Death 48 Female 247 lb 9/14/2011 Physician United States
Primary
Secondary
Concomitant
Neuralgia Other Serious 1/1/2009 60 Female 9/19/2011 Consumer United States
Primary
Secondary
Concomitant
Carotid Artery Occlusion Other Serious 1/1/2009 60 Female 9/27/2011 Consumer United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 2/1/2007 61 Female 170 lb 10/10/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization Female 11/4/2011 Consumer United States
Primary
Secondary
Laceration Other Serious 1/1/2003 66 Female 11/8/2011 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 1/1/2011 61 Female 11/10/2011 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 3/16/2011 61 Female 150 lb 12/14/2011 Consumer United States
Primary
Concomitant
Erythema Other Serious 4/1/2010 63 Female 130 lb 12/23/2011 Consumer United States
Primary
Concomitant
Rash Macular 1/1/2009 48 Female 239 lb 1/27/2012 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Recurrent Other Serious Male 151 lb 1/27/2012 Physician United States
Primary
Concomitant
Hypoaesthesia 10/1/2010 37 Female 1/27/2012 Consumer United States
Primary
Concomitant
Pulmonary Congestion 2/11/2011 58 Female 150 lb 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Warmth 3/2/2011 56 Female 225 lb 1/27/2012 Consumer United States
Primary
Concomitant
Granuloma Annulare 1/1/2008 57 Female 166 lb 1/27/2012 Consumer United States
Primary
Concomitant
Arthralgia 12/3/2010 72 Female 195 lb 1/27/2012 Consumer United States
Primary
Concomitant
Wound Infection 4/14/2011 63 Female 1/28/2012 Consumer United States
Primary
Concomitant
Device Malfunction 4/23/2011 66 Female 1/28/2012 Consumer United States
Primary
Concomitant
Fatigue Female 195 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 2/1/2011 63 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Swelling 12/2/2011 53 Female 1/29/2012 Consumer United States
Primary
Concomitant
Sinus Disorder 1/1/2011 75 Female 1/29/2012 Consumer United States
Primary
Concomitant
Nasal Congestion Female 165 lb 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 1/1/2010 72 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 8/1/2011 65 Female 1/28/2012 Consumer United States
Primary
Concomitant
Weight Decreased 2/1/2011 63 Female 155 lb 1/28/2012 Consumer United States
Primary
Concomitant
Drug Dose Omission Other Serious 1/1/2012 64 Female 108 lb 2/3/2012 Consumer United States
Primary
Concomitant
Hyperkeratosis Hospitalization 1/1/2011 55 Female 200 lb 2/14/2012 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2008 62 Female 110 lb 3/2/2012 Physician United States
Primary
Concomitant
Vaginal Ulceration Hospitalization 62 Female 187 lb 3/26/2012 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2011 60 Female 235 lb 3/22/2012 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 5/1/2011 60 Female 235 lb 4/10/2012 Physician United States
Primary
Concomitant
Skin Ulcer Death 3/2/2008 78 Female 134 lb 4/30/2012 Consumer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 4/7/2012 Female 162 lb 5/9/2012 Physician United States
Primary
Concomitant
Sinusitis Hospitalization 12/1/2011 64 Female 166 lb 6/5/2012 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 4/7/2012 Female 162 lb 6/7/2012 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2009 45 Female 216 lb 6/14/2012 Consumer United States
Primary
Concomitant
Thalamic Infarction Other Serious 5/19/2012 66 Female 186 lb 6/22/2012 Other Health Professional United States
Primary
Concomitant
Asthenia Other Serious 1/1/2000 76 Female 6/28/2012 Other Health Professional United States
Primary
Concomitant
Sinusitis Hospitalization 12/1/2011 64 Female 166 lb 7/9/2012 Other Health Professional United States
Primary
Concomitant
Fall 11/2/2011 73 Female 239 lb 8/2/2012 Other Health Professional United States
Primary
Concomitant
Malaise 2010 Female 262 lb 1/28/2013 Consumer Us
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Lung Death 11/2006 Female 10/19/2012 Physician Us
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 7/30/2010 34 Female 245 lb 11/16/2012 Other Health Professional Us
Primary
Concomitant
Vomiting Hospitalization Female 151 lb 9/19/2012 Physician Us
Primary
Concomitant
Visual Impairment Other Serious 4/2012 Female 12/31/2012 Physician Country Not Specified
Primary
Concomitant
Wound Haemorrhage Other Serious 2012 Female 10/29/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Pulmonary Mass Other Serious 6/6/2012 70 Male 10/2/2012 Consumer Us
Primary
Concomitant
Injection Site Pruritus 12/29/2011 45 Female 10/25/2012 Other Health Professional Us
Primary
Concomitant
Paraesthesia Other Serious 5/20/2004 56 Female 150 lb 10/24/2012 Consumer Us
Primary
Concomitant
Injection Site Rash 4/15/2012 35 Female 145 lb 10/23/2012 Consumer Us
Primary
Concomitant
Sinusitis 7/20/2012 61 Female 136 lb 10/26/2012 Consumer Us
Primary
Concomitant
Infected Bites 7/18/2012 57 Female 220 lb 10/26/2012 Physician Us
Primary
Concomitant
Onychomycosis 8/1/2010 59 Female 138 lb 10/26/2012 Physician Us
Primary
Concomitant
Injection Site Pruritus 6/20/2012 36 Female 153 lb 10/26/2012 Consumer Us
Primary
Concomitant
Therapeutic Response Decreased 2/1/2012 53 Female 90 lb 10/25/2012 Physician Us
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2010 62 Female 128 lb 11/7/2012 Consumer Us
Primary
Secondary
Concomitant
Fatigue 10/26/2011 36 Female 11/7/2012 Other Health Professional Us
Primary
Concomitant
Sinusitis 9/15/2011 68 Female 11/7/2012 Other Health Professional Us
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/15/2011 69 Female 12/11/2012 Physician Us
Primary
Secondary
Concomitant
Septic Shock Death 12/24/2011 57 Female 140 lb 11/13/2012 Other Health Professional Us
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/2012 Female 210 lb 11/21/2012 Consumer Us
Primary
Concomitant
Weight Decreased 6/2012 60 Female 12/4/2012 Consumer Us
Primary
Concomitant
Tuberculosis Hospitalization 9/2012 Female 113 lb 12/11/2012 Consumer Us
Primary
Concomitant
Septic Shock Hospitalization 12/19/2012 73 Female 245 lb 3/29/2013 Physician Us
Primary
Concomitant
Vulvovaginal Pruritus 12/1/2011 44 Female 235 lb 1/7/2013 Consumer Us
Primary
Concomitant
Arthralgia 7/2011 88 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Alopecia 4/5/2012 61 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Musculoskeletal Discomfort 53 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pruritus Female 126 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant

Drug Data