Methotrexate combined with Metoclopramide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Other Serious 5/1/2005 Female 110 lb 2/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/30/2005 62 Male 2/22/2006 Other Health Professional Mexico
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 12/4/2005 21 Male 159 lb 2/17/2006 United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 12/30/2005 62 Male 3/6/2006 Other Health Professional Mexico
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/30/2005 62 Male 3/17/2006 Other Health Professional Mexico
Primary
Secondary
Concomitant
Sedation Hospitalization 6/16/2003 49 Female 231 lb 3/23/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2000 58 Female 141 lb 3/28/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/25/2005 Female 119 lb 4/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pustular Psoriasis Disability 2/16/2006 48 Female 209 lb 5/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 5/20/2006 61 Female 159 lb 6/5/2006 Consumer United States
Primary
Concomitant
Large Intestinal Haemorrhage Other Serious 6/28/2006 Female 8/4/2006 Consumer Canada
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 7/30/2006 57 Male 149 lb 8/10/2006 Pharmacist United States
Primary
Concomitant
Large Intestinal Haemorrhage Other Serious 7/12/2006 Female 9/22/2006 Physician Canada
Primary
Concomitant
Respiratory Failure Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Septic Shock Life Threatening 12/30/2005 62 Male 10/4/2006 Other Health Professional Mexico
Primary
Secondary
Concomitant
Vertigo Life Threatening 8/6/2005 Female 10/4/2006 Physician Finland
Primary
Concomitant
Vertigo Other Serious 8/6/2005 Female 10/4/2006 Physician Finland
Primary
Concomitant
Septic Shock Life Threatening 12/30/2005 62 Male 10/11/2006 Other Health Professional Mexico
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2006 Female 160 lb 11/16/2006 Consumer United States
Primary
Concomitant
Skin Cancer Other Serious 3/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/26/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Hyperglycaemia Other Serious 11/13/2006 46 Female 12/15/2006 Pharmacist United Kingdom
Primary
Concomitant
Polyneuropathy Hospitalization 9/1/2006 Female 2/13/2007 Physician Norway
Primary
Concomitant
Vision Blurred 1/1/2005 66 Female 200 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 8/20/2006 70 Female 6/29/2007 Other Health Professional Sweden
Primary
Concomitant
Hypoglycaemia Life Threatening 4/1/2007 60 Female 220 lb 7/6/2007 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/20/2006 Female 8/14/2007 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 9/28/2007 Other Health Professional Sweden
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 13 Male 10/11/2007 Physician United States
Primary
Secondary
Swelling Face Other Serious 1/1/2007 Female 191 lb 10/16/2007 United States
Primary
Concomitant
Weight Decreased 8/26/2005 54 Female 12/15/2006 Physician United States
Primary
Concomitant
Alveolitis Fibrosing Life Threatening 61 Female 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 5/1/2007 Female 11/16/2007 Belgium
Primary
Concomitant
Syncope Life Threatening 7/11/2007 Female 190 lb 11/21/2007 Physician United States
Primary
Concomitant
Yellow Skin Other Serious 1/1/2005 Male 12/6/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 12/20/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 12/26/2007 Physician Germany
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2006 75 Female 128 lb 1/7/2008 Physician United States
Primary
Concomitant
Oesophageal Cancer Metastatic Other Serious 7/30/2006 Female 157 lb 1/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Carcinoma In Situ Of Skin Other Serious 11/15/2006 Female 99 lb 1/10/2008 Physician United Kingdom
Primary
Concomitant
Infusion Related Reaction Other Serious 9/26/2006 78 Female 130 lb 1/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Disease Other Serious 4/2/2007 Male 181 lb 1/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization 78 Female 1/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Cancer Metastatic Other Serious 3/22/2005 Female 157 lb 1/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 70 Female 1/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
Trichophytosis Other Serious 64 Female 1/31/2008
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/11/2008 Female 2/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 9/26/2006 78 Female 130 lb 3/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Pain 11/25/2007 Male 139 lb 3/15/2008 Consumer United States
Primary
Concomitant
Accidental Needle Stick Female 3/15/2008 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 78 Female 3/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Hospitalization 12/1/2007 Female 139 lb 3/24/2008 United States
Primary
Concomitant
Gastrointestinal Disorder Other Serious 8/29/2007 Female 119 lb 3/28/2008 Consumer United Kingdom
Primary
Concomitant
Exsanguination Life Threatening 10/23/1986 23 Male 154 lb 3/31/2008 Physician United Kingdom
Primary
Concomitant
Alveolitis Fibrosing Life Threatening 9/15/2007 Female 194 lb 4/2/2008 Physician United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 2/4/2008 Female 254 lb 4/17/2008 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 2/25/2007 Female 130 lb 6/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Other Serious 67 Female 7/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 5/6/2008 Female 128 lb 7/30/2008 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/11/2008 Female 8/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 5/6/2008 Female 128 lb 8/15/2008 Physician Netherlands
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 5/6/2008 Female 128 lb 8/19/2008 Physician Netherlands
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 5/20/2008 Female 112 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 44 Female 9/17/2008
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/30/2005 Male 9/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tic Other Serious 1/28/2008 56 Female 8/19/2008 Other Health Professional United States
Primary
Concomitant
Pruritus Hospitalization 9/1/2007 29 Female 9/25/2008 Other Health Professional United States
Primary
Concomitant
Lung Cancer Metastatic Other Serious 9/11/2008 Female 119 lb 11/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Mass Other Serious 9/1/2006 54 Female 174 lb 3/3/2008 Other Health Professional United States
Primary
Concomitant
Mass Other Serious 9/1/2006 54 Female 174 lb 9/9/2008 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 Male 150 lb 11/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 11/24/2008 Consumer France
Primary
Secondary
Concomitant
Lung Cancer Metastatic Other Serious 9/11/2008 Female 119 lb 12/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization Female 165 lb 12/4/2008 Germany
Primary
Concomitant
Oedema Peripheral 8/1/2008 Female 140 lb 12/12/2008 United States
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Vitamin D Decreased 8/1/2008 Female 165 lb 12/12/2008 Consumer United States
Primary
Concomitant
Nasopharyngitis 10/2/2008 Female 128 lb 12/12/2008 United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 3/14/2008 Female 97 lb 12/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 12/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization Female 165 lb 12/26/2008 Germany
Primary
Concomitant
Sensation Of Heaviness 9/1/2008 Female 1/6/2009 Consumer
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Sensation Of Heaviness 9/1/2008 Female 1/16/2009 Consumer
Primary
Concomitant
Dyspnoea Other Serious 2/3/2008 Female 254 lb 1/21/2009 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 11/28/2008 Female 163 lb 2/4/2009 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 11/28/2008 Female 163 lb 2/6/2009 Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2003 77 Female 161 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Fall Death 11/17/2008 79 Female 106 lb 3/26/2009 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 4/3/2009 Male 5/15/2009 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/10/2009 Male 176 lb 5/20/2009 Physician Australia
Primary
Secondary
Concomitant
Lung Cancer Metastatic Other Serious Female 119 lb 5/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 5 Female 5/22/2009 Other Health Professional Malawi
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12 Female 5/22/2009 Other Health Professional Malawi
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 5/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 5/11/2009 Female 150 lb 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral 8/1/2008 Female 140 lb 6/11/2009 United States
Primary
Concomitant
Iritis Other Serious 3/1/2008 Female 130 lb 6/15/2009 Physician Canada
Primary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 6/30/2009 United Kingdom
Primary
Secondary
Concomitant
Colon Cancer Other Serious 5/11/2009 Female 150 lb 7/20/2009 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 7/21/2009 Female 120 lb 8/7/2009 Physician Poland
Primary
Concomitant
Mitral Valve Incompetence Other Serious 1/1/2007 Male 194 lb 8/21/2009 Brazil
Primary
Concomitant
Overdose Life Threatening 7/5/2008 14 Male 101 lb 9/1/2009 Poland
Primary
Secondary
Concomitant
Injection Site Extravasation Female 9/12/2009 Consumer United States
Primary
Concomitant
Dysentery 7/1/2009 Male 135 lb 9/19/2009 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Life Threatening 7/5/2008 14 Male 101 lb 9/14/2009 Physician Poland
Primary
Secondary
Concomitant
Pregnancy Hospitalization 8/29/2005 25 Female 9/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Life Threatening 7/5/2008 14 Male 101 lb 9/21/2009 Physician Poland
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 10/1/2009 United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/7/2009 43 Female 201 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 5/20/2009 19 Female 10/12/2009 Pharmacist New Zealand
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/15/2009 Female 123 lb 10/28/2009 United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 10/6/2009 Male 11/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Oesophageal Carcinoma Required Intervention 5/5/2009 77 Male 12/22/2009 Consumer United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/12/2009 Female 15 lb 12/30/2009 United States
Primary
Secondary
Concomitant
Listeria Sepsis Hospitalization 9/3/2007 58 Female 132 lb 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/15/2009 Female 123 lb 1/18/2010 United Kingdom
Primary
Concomitant
Visual Impairment Hospitalization 11/1/2009 Male 1/22/2010 Physician Germany
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3 Female 29 lb 1/20/2010 Other Health Professional Canada
Primary
Concomitant
Lung Neoplasm Hospitalization 14 Male 95 lb 1/20/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 6/21/2009 72 Female 1/28/2010 Other Health Professional Argentina
Primary
Secondary
Concomitant
Syncope Hospitalization 10/15/2009 Female 111 lb 2/16/2010 Physician United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/16/2009 Female 192 lb 2/22/2010 Physician France
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/10/2010 55 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Disability 6/1/2007 70 Female 219 lb 4/15/2010 United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2009 38 Female 123 lb 5/28/2010 Netherlands
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/17/2010 United States
Primary
Concomitant
Tinnitus Disability 64 Female 6/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Lesion Hospitalization 4/14/2010 3 Female 43 lb 6/17/2010 United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 1/1/2009 61 Female 6/15/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/4/2010 3 Female 43 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2009 38 Female 123 lb 7/9/2010 Physician Netherlands
Primary
Concomitant
Vomiting 11/5/2007 59 Female 115 lb 7/17/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2009 38 Female 123 lb 7/21/2010 Physician Netherlands
Primary
Concomitant
Stem Cell Transplant Other Serious 3/11/2009 48 Female 84 lb 7/19/2010 Physician Japan
Primary
Concomitant
Suicidal Ideation Other Serious 3/1/2008 55 Female 8/23/2010 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 59 Female 132 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2009 38 Female 123 lb 8/25/2010 Physician Netherlands
Primary
Concomitant
Sepsis Life Threatening 1/11/2010 62 Female 148 lb 8/31/2010 Physician Israel
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 6/1/2009 59 Female 132 lb 9/1/2010 Physician Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 9/10/2010 Physician Sweden
Primary
Concomitant
Interacting

Drug Data