Lamictal combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Septic Shock Hospitalization 11/28/2005 Female 1/5/2006 Physician United States
Primary
Secondary
Concomitant
Thirst Other Serious 2/24/2006 Female 172 lb 3/8/2006 Consumer United States
Primary
Concomitant
Rash Hospitalization 1/1/2006 40 Male 3/16/2006 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 2/15/2006 Female 152 lb 5/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 4/1/2005 55 Female 8/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/15/2006 Female 152 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 3/2/2006 Male 12/13/2006 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 3/1/2006 Male 260 lb 1/25/2007 Physician United States
Primary
Concomitant
Pseudoporphyria Other Serious 4/1/2005 55 Female 2/27/2007 United Kingdom
Primary
Concomitant
Rash Other Serious 1/20/2006 40 Male 2/26/2007 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious Female 2/28/2007 Consumer United States
Primary
Concomitant
Benign Intracranial Hypertension Other Serious 1/1/2006 15 Female 150 lb 3/21/2007 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious 6/15/2007 Female 7/27/2007 Consumer Australia
Primary
Concomitant
Somnolence 3/1/2007 Female 300 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 11/28/2005 Female 10/25/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2003 Female 130 lb 12/17/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2007 53 Female 250 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/1/2008 74 Female 220 lb 2/20/2008 Pharmacist France
Primary
Concomitant
Surgery Other Serious 6/2/2005 Female 152 lb 3/1/2008 Consumer United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/1/2008 74 Female 220 lb 3/24/2008 Pharmacist France
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 1/1/2008 74 Female 220 lb 4/11/2008 Pharmacist France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 160 lb 5/8/2008 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 5/12/2008 82 Female 5/23/2008 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased 45 Male 6/29/2008 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 5/12/2008 82 Female 7/28/2008 Consumer United States
Primary
Concomitant
Crystal Urine Present Hospitalization 4/1/2008 23 Male 154 lb 7/7/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2007 63 Male 8/25/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 1/1/2007 63 Male 241 lb 9/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 9/14/2008 50 Female 9/23/2008 Consumer Australia
Primary
Concomitant
Convulsion Hospitalization 9/14/2008 50 Female 10/16/2008 Consumer Australia
Primary
Concomitant
Nasopharyngitis 12/1/2007 Female 150 lb 12/1/2008 Physician United States
Primary
Concomitant
Convulsion Hospitalization 9/14/2008 50 Female 12/16/2008 Consumer Australia
Primary
Concomitant
Partial Seizures Other Serious 12/1/2007 50 Female 12/19/2008 Consumer Australia
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 12/19/2008 Consumer United States
Primary
Concomitant
Convulsion Other Serious 12/6/2007 50 Female 1/2/2009 Consumer Australia
Primary
Concomitant
Fall Other Serious 12/6/2007 50 Female 1/7/2009 Consumer Australia
Primary
Concomitant
Convulsion Other Serious 12/6/2007 50 Female 1/30/2009 Consumer Australia
Primary
Concomitant
Vomiting Other Serious 51 Female 198 lb 2/11/2009 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 3/25/2008 40 Female 2/27/2009 Consumer United States
Primary
Concomitant
Infection 10/2/2008 Female 2/27/2009 Consumer United States
Primary
Concomitant
Convulsion Other Serious 12/6/2007 50 Female 3/18/2009 Consumer Australia
Primary
Concomitant
Grand Mal Convulsion 51 Female 6/15/2009 Other Health Professional Australia
Primary
Concomitant
Grand Mal Convulsion 51 Female 6/16/2009 Other Health Professional Australia
Primary
Concomitant
Grand Mal Convulsion Other Serious 51 Female 6/16/2009 Other Health Professional Australia
Primary
Concomitant
Convulsion Other Serious 12/6/2007 49 Female 6/19/2009 Consumer Australia
Primary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Suicide Attempt Other Serious 2/2/2001 30 Female 273 lb 9/23/2009 United States
Primary
Concomitant
Tremor 4/25/2009 40 Female 9/24/2009 Physician United States
Primary
Concomitant
Oesophageal Perforation Other Serious 4/1/2009 Female 185 lb 10/16/2009 United States
Primary
Concomitant
Pancreatitis Hospitalization 6/5/2009 38 Female 11/25/2009 Physician France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/5/2009 Female 12/2/2009 Physician France
Primary
Secondary
Concomitant
Injection Site Pain Female 197 lb 1/29/2010 United States
Primary
Concomitant
Sinusitis 8/1/2009 Male 155 lb 1/30/2010 Other Health Professional United States
Primary
Concomitant
Stress Hospitalization 12/29/2009 Female 135 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 7/15/2006 60 Male 5/18/2010 Consumer United Kingdom
Primary
Concomitant
Cellulitis Other Serious 44 Female 6/4/2010 Consumer United States
Primary
Concomitant
Drug Dose Omission Hospitalization 3/20/2009 10 Female 112 lb 6/15/2010 Physician United States
Primary
Secondary
Convulsion Hospitalization 3/20/2009 13 Female 112 lb 7/8/2010 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 7/15/2006 60 Male 176 lb 7/12/2010 Consumer United Kingdom
Primary
Concomitant
Cholesterosis Other Serious 5/20/2008 25 Female 1/17/2011 Lawyer United States
Primary
Concomitant
Influenza Like Illness 1/1/2010 52 Female 262 lb 1/29/2011 Consumer United States
Primary
Secondary
Concomitant
Device Malfunction 7/1/2010 40 Female 1/29/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Hospitalization 12/15/2010 16 Male 126 lb 2/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 1/31/2011 52 Female 163 lb 2/7/2011 Consumer United States
Primary
Concomitant
Convulsion Other Serious 12/6/2007 49 Female 2/28/2011 Other Health Professional Australia
Primary
Concomitant
Skin Burning Sensation 46 Female 2/28/2011 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 5/20/2008 25 Female 178 lb 3/10/2011 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 1/31/2011 52 Female 163 lb 3/1/2011 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 2/25/2011 38 Female 291 lb 3/17/2011 Consumer Canada
Primary
Concomitant
Suicidal Ideation Hospitalization 2/25/2011 38 Female 291 lb 6/30/2011 Consumer Canada
Primary
Concomitant
Pneumonia Hospitalization 2/15/2006 58 Female 152 lb 7/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tenderness Hospitalization 3/15/2011 71 Female 304 lb 8/10/2011 Physician United States
Primary
Concomitant
Neuralgia Other Serious 1/1/2009 60 Female 9/19/2011 Consumer United States
Primary
Secondary
Concomitant
Carotid Artery Occlusion Other Serious 1/1/2009 60 Female 9/27/2011 Consumer United States
Primary
Secondary
Concomitant
Convulsion Hospitalization Female 10/7/2011 Physician United States
Primary
Secondary
Concomitant
Dry Eye Other Serious Female 10/11/2011 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization Female 10/14/2011 Physician United States
Primary
Secondary
Concomitant
Sinus Disorder 12/12/2010 61 Female 175 lb 10/28/2011 Consumer United States
Primary
Concomitant
Spinal Cord Compression Hospitalization Female 11/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Female 11/17/2011 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 5/20/2008 27 Female 207 lb 11/30/2011 Other Health Professional United States
Primary
Concomitant
Bone Lesion Death Female 12/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Bronchitis 3/1/2011 57 Female 12/13/2011 Physician United States
Primary
Concomitant
Sepsis Hospitalization 6/29/2011 60 Female 12/19/2011 Physician Ireland
Primary
Concomitant
Migraine Other Serious 48 Female 185 lb 12/29/2011 Consumer United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 12/15/2011 57 Female 1/16/2012 Physician Japan
Primary
Secondary
Concomitant
Bone Lesion Other Serious Female 1/27/2012 Lawyer United States
Primary
Secondary
Concomitant
Psoriasis 3/1/2011 49 Female 1/28/2012 Consumer United States
Primary
Concomitant
Arthralgia 2/22/2011 51 Female 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 11/1/2010 50 Female 1/27/2012 Consumer United States
Primary
Concomitant
Diarrhoea 2/1/2011 48 Female 143 lb 1/27/2012 Consumer United States
Primary
Concomitant
Fatigue 2/18/2011 54 Female 135 lb 1/27/2012 Consumer United States
Primary
Concomitant
Arthralgia 5/27/2011 39 Female 1/28/2012 Consumer United States
Primary
Concomitant
Influenza 1/1/2011 51 Male 178 lb 1/28/2012 Consumer United States
Primary
Concomitant
Pain 7/29/2011 54 Female 1/28/2012 Consumer United States
Primary
Concomitant
Skin Papilloma Hospitalization Female 1/31/2012 Physician United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/15/2011 57 Female 1/31/2012 Physician Japan
Primary
Secondary
Concomitant
Injection Site Papule 2/1/2010 Female 1/28/2012 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 1/30/2012 57 Female 236 lb 2/10/2012 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/30/2012 57 Female 236 lb 2/24/2012 Physician United States
Primary
Secondary
Concomitant
Abdominal Discomfort 2/25/2012 37 Female 3/12/2012 Consumer United States
Primary
Concomitant
Night Sweats Other Serious 3/11/2012 58 Female 5/8/2012 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 3/11/2012 58 Female 5/15/2012 Consumer United States
Primary
Concomitant
Lumbar Radiculopathy Hospitalization 8/10/2010 51 Female 5/23/2012 Physician United States
Primary
Secondary
Concomitant
Fall Other Serious 3/11/2012 58 Female 98 lb 6/28/2012 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 6/1/2010 59 Female 340 lb 7/26/2012 Consumer United States
Primary
Concomitant
Crohn's Disease Other Serious 8/10/2012 25 Male 223 lb 8/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 2/2012 52 Female 130 lb 12/4/2012 Consumer Us
Primary
Concomitant
Death Death Female 291 lb 9/4/2012 Other Health Professional Ca
Primary
Concomitant
Pneumonitis Chemical Hospitalization 7/5/2012 60 Male 179 lb 8/1/2012 Us
Primary
Secondary
Concomitant
Tendon Injury Other Serious Female 11/19/2012 Other Health Professional Au
Primary
Concomitant
Rheumatoid Arthritis Female 445 lb 10/23/2012 Consumer Us
Primary
Concomitant
Weight Decreased Other Serious 2009 56 Female 10/25/2012 Consumer Country Not Specified
Primary
Concomitant
Bronchitis 11/22/2011 22 Female 10/24/2012 Physician Us
Primary
Concomitant
Injection Site Pruritus 8/29/2011 20 Female 220 lb 10/24/2012 Physician Us
Primary
Concomitant
Ocular Hyperaemia 8/3/2012 39 Female 235 lb 10/23/2012 Physician Us
Primary
Concomitant
Rash Pruritic 4/2012 38 Female 11/8/2012 Physician Us
Primary
Concomitant
Parosmia 10/2010 56 Female 226 lb 11/13/2012 Other Health Professional Us
Primary
Concomitant
Photopsia 56 Female 1/2/2013 Consumer Us
Primary
Concomitant
Hypotension Other Serious 10/2012 Female 1/8/2013 Other Health Professional Au
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 190 lb 1/28/2013 Physician Us
Primary
Concomitant
Nausea 1/2012 39 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Pain 1/2012 39 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Rheumatoid Arthritis 1/2012 Female 125 lb 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Skin Exfoliation 11/2011 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Reaction 2012 NotSpecified 200 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pain 6/14/2012 47 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Pallor 4/16/2012 52 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Weight Increased 2011 Female 169 lb 1/29/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Injection Site Bruising 6/2012 42 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Rheumatoid Arthritis NotSpecified 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Paraesthesia 10/2012 76 Female 2/1/2013 Consumer Country Not Specified
Primary
Concomitant
Drug Interaction NotSpecified 2/27/2013 Consumer Us
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/9/2013 52 Male 5/1/2013 Physician Fr
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization Female 5/21/2013 Consumer Us
Primary
Concomitant
Pruritus 5/17/2013 14 Female 173 lb 7/8/2013 Other Health Professional Us
Primary
Concomitant
Depression Hospitalization 5/8/2013 59 Female 155 lb 6/24/2013 Other Health Professional Ca
Primary
Concomitant
Suicidal Ideation Other Serious Female 8/6/2013 Consumer Us
Primary
Concomitant
Therapeutic Response Decreased Other Serious 57 Female 113 lb 8/20/2013 Physician Us
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/3/2013 46 Female 208 lb 10/16/2013 Consumer Us
Primary
Concomitant
Depressed Mood 66 Male 260 lb 9/9/2013 Consumer Us
Primary
Concomitant
Urticaria Female 135 lb 10/1/2013 Physician Us
Primary
Concomitant
Drug Ineffective Female 170 lb 10/1/2013 Physician Us
Primary
Concomitant
Drug Ineffective Female 10/1/2013 Consumer Us
Primary
Concomitant
Injection Site Erythema 6/2/2013 33 Female 145 lb 10/2/2013 Physician Us
Primary
Concomitant
Swelling 10/30/2012 39 Female 230 lb 10/3/2013 Consumer Us
Primary
Concomitant
Injection Site Bruising 54 Female 170 lb 10/4/2013 Physician Us
Primary
Concomitant
Skin Atrophy Hospitalization Male 10/29/2013 Consumer Country Not Specified
Primary
Concomitant
Tooth Extraction Other Serious 2013 67 Female 160 lb 10/18/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data