Methotrexate combined with Vitamin D3

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Hospitalization 11/10/2005 79 Female 1/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/10/2005 79 Female 1/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 5/1/2006 Physician Brazil
Primary
Concomitant
Shock Hospitalization 1/1/2004 53 Female 6/29/2006 Other Health Professional France
Primary
Secondary
Concomitant
Myasthenia Gravis Hospitalization 1/12/2006 Female 7/24/2006 Other Health Professional Italy
Primary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 8/16/2006 Physician Brazil
Primary
Concomitant
Renal Impairment Other Serious 5/1/2004 58 Male 11/3/2006 Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 50 Female 1/4/2007 Pharmacist Canada
Primary
Concomitant
Vascular Purpura Hospitalization 11/21/2006 Male 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Fistula Other Serious 3/1/2007 Male 163 lb 8/14/2007 Physician Canada
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/8/2007 Female 185 lb 4/14/2008 Consumer Canada
Primary
Secondary
Concomitant
Skin Reaction Death Male 4/14/2008
Primary
Secondary
Concomitant
Skin Reaction Death Male 4/14/2008
Primary
Secondary
Concomitant
Peritonitis Life Threatening 1/9/2007 Female 115 lb 4/17/2008 Physician France
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 8/6/2008 Female 12/17/2008 Physician United States
Primary
Concomitant
Meniscus Operation Hospitalization 12/1/2008 Female 1/20/2009 Consumer Germany
Primary
Concomitant
Chondropathy Hospitalization 12/1/2008 Female 1/22/2009 Consumer Germany
Primary
Concomitant
Chondropathy Hospitalization 12/1/2008 Female 2/5/2009 Consumer Germany
Primary
Concomitant
Pain Other Serious Female 2/20/2009 Consumer Germany
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 12/31/2008 Female 218 lb 3/13/2009 Consumer United States
Primary
Concomitant
Visual Acuity Reduced 2/1/2009 Female 115 lb 3/14/2009 Consumer United States
Primary
Concomitant
Rash Papular Other Serious 1/1/2009 Female 135 lb 3/18/2009 Physician United States
Primary
Concomitant
Rash Vesicular Other Serious 1/1/2009 Female 135 lb 3/25/2009 Physician United States
Primary
Concomitant
Metastasis Other Serious 3/1/2009 Female 4/2/2009 Physician Russian Federation
Primary
Concomitant
Pneumonitis Hospitalization 3/25/2009 Female 168 lb 4/8/2009 Hungary
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 4/4/2009 58 Female 4/16/2009 Consumer Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/4/2009 58 Female 4/30/2009 Other Health Professional Brazil
Primary
Concomitant
Pneumonitis Hospitalization 3/25/2009 Female 168 lb 5/1/2009 Hungary
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/25/2009 Female 168 lb 5/18/2009 Hungary
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/11/2009 Female 165 lb 6/8/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 2/11/2009 Female 165 lb 6/18/2009 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 3/1/2008 Female 8/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Injection Site Pain 7/25/2009 Female 250 lb 9/19/2009 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/1/2009 Male 12/11/2009 Physician United States
Primary
Concomitant
Colonic Stenosis Hospitalization 1/8/2010 Female 1/21/2010 United States
Primary
Concomitant
Paranasal Sinus Hypersecretion 2/1/2009 Female 177 lb 1/29/2010 Consumer United States
Primary
Concomitant
Colon Cancer Hospitalization 10/29/2009 Female 3/19/2010 United States
Primary
Concomitant
Colon Cancer Hospitalization 10/29/2009 80 Female 5/4/2010 United States
Primary
Concomitant
Neutropenia Other Serious 3/1/2008 73 Female 5/20/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Female 145 lb 5/11/2010 Other Health Professional United States
Primary
Concomitant
Neutropenia Life Threatening 3/1/2008 73 Female 6/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/15/2010 64 Female 129 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 6/15/2010 64 Female 129 lb 7/9/2010 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/15/2010 64 Female 129 lb 7/13/2010 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 7/27/2010 58 Female 150 lb 8/5/2010 Physician Canada
Primary
Concomitant
Gastrointestinal Disorder Hospitalization 7/1/2010 51 Female 8/12/2010 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 6/1/2010 76 Female 135 lb 8/19/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/7/2010 54 Female 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Female 145 lb 7/26/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 8/9/2010 75 Male 227 lb 9/9/2010 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 5/1/2004 58 Male 9/17/2010 Physician Japan
Primary
Concomitant
Colon Cancer Other Serious 7/29/2010 57 Female 238 lb 9/20/2010 Physician Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 5/7/2010 54 Female 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 7/27/2010 58 Female 150 lb 10/8/2010 Physician Canada
Primary
Concomitant
Skin Disorder Other Serious 7/12/2010 66 Female 10/6/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/1/2010 57 Female 11/17/2010 Consumer Australia
Primary
Concomitant
Urticaria Other Serious 10/19/2010 46 Female 11/25/2010 Physician United States
Primary
Concomitant
Skin Disorder Other Serious 7/12/2010 66 Female 11/30/2010 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 8/30/2010 43 Female 12/15/2010 United States
Primary
Concomitant
Injection Site Pruritus 10/19/2010 12/28/2010 Consumer United States
Primary
Concomitant
Laparotomy Death 11/20/2010 73 Female 12/30/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Laparotomy Death 11/20/2010 73 Female 1/10/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Blood Creatine Abnormal Other Serious 10/19/2010 46 Female 1/12/2011 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/15/2010 64 Female 129 lb 3/22/2013 Physician Us
Primary
Concomitant
Rash Hospitalization 10/21/2009 63 Female 157 lb 10/23/2012 Consumer Us
Primary
Concomitant
Venous Thrombosis Limb Other Serious 8/13/2011 75 Female 110 lb 3/11/2013 Consumer Us
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 5/27/2012 61 Female 384 lb 2/6/2013 Physician Us
Primary
Concomitant
Swelling Face Hospitalization 4/27/2012 75 Female 12/27/2012 Physician Us
Primary
Concomitant
Walking Aid User Other Serious 2011 43 Female 11/2/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Vomiting Other Serious 2012 61 Female 9/21/2012 Other Health Professional Ca
Primary
Concomitant
Vomiting Hospitalization 2/2012 51 Female 117 lb 9/6/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious Female 8/28/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Pruritus Other Serious 6/11/2011 74 Female 74 lb 8/31/2012 Physician Us
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 151 lb 9/19/2012 Physician Us
Primary
Concomitant
Rheumatoid Lung Hospitalization 6/18/2012 85 Female 123 lb 9/18/2012 Physician Country Not Specified
Primary
Concomitant
Lymphoproliferative Disorder Death 8/2012 Male 10/2/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Wrist Fracture Female 165 lb 9/27/2012 Other Health Professional Us
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 10/22/2012 Physician Us
Primary
Concomitant
Sudden Cardiac Death Death 7/6/2012 81 Male 163 lb 12/27/2012 Physician Country Not Specified
Primary
Concomitant
Rash Maculo-papular Hospitalization Female 158 lb 10/12/2012 Pharmacist Br
Primary
Concomitant
Injection Site Pain Female 173 lb 10/23/2012 Physician Us
Primary
Concomitant
Weight Increased Female 142 lb 10/23/2012 Consumer Us
Primary
Concomitant
Back Pain 9/10/2012 56 Female 551 lb 10/23/2012 Physician Us
Primary
Concomitant
Drug Ineffective Female 189 lb 10/23/2012 Physician Us
Primary
Concomitant
Increased Tendency To Bruise Female 165 lb 10/23/2012 Physician Us
Primary
Concomitant
Influenza 3/2012 48 Female 164 lb 10/25/2012 Physician Us
Primary
Concomitant
Platelet Count Decreased 3/27/2012 60 Male 10/25/2012 Physician Us
Primary
Concomitant
Rash Male 10/24/2012 Physician Us
Primary
Concomitant
Onychomycosis 63 Female 10/24/2012 Physician Us
Primary
Concomitant
Injection Site Swelling Female 126 lb 10/24/2012 Physician Us
Primary
Concomitant
Vulvovaginal Mycotic Infection 11/28/2011 46 Female 147 lb 10/24/2012 Other Health Professional Us
Primary
Concomitant
Respiratory Tract Infection 11/14/2011 45 Female 112 lb 10/24/2012 Other Health Professional Us
Primary
Concomitant
Injection Site Bruising 58 Female 185 lb 10/24/2012 Physician Us
Primary
Concomitant
Sinusitis 57 Female 10/24/2012 Physician Us
Primary
Concomitant
Injection Site Warmth 62 Female 212 lb 10/24/2012 Other Health Professional Us
Primary
Concomitant
Pollakiuria 12/14/2011 43 Female 10/24/2012 Physician Us
Primary
Concomitant
Nonspecific Reaction Female 10/25/2012 Physician Us
Primary
Concomitant
Weight Increased 2/29/2012 52 Female 10/25/2012 Physician Us
Primary
Concomitant
Menstruation Irregular 46 Female 10/25/2012 Physician Us
Primary
Concomitant
Stomatitis Female 130 lb 10/25/2012 Physician Us
Primary
Concomitant
Injection Site Pain 3/19/2012 60 Female 183 lb 10/25/2012 Physician Us
Primary
Concomitant
Injection Site Bruising 6/29/2012 61 Female 170 lb 10/26/2012 Consumer Us
Primary
Concomitant
Infection 7/23/2012 43 Female 124 lb 10/26/2012 Consumer Us
Primary
Concomitant
Fatigue 7/5/2012 65 Female 10/23/2012 Consumer Us
Primary
Concomitant
Throat Irritation 8/14/2012 63 Female 10/23/2012 Other Health Professional Us
Primary
Concomitant
Pneumonia Bacterial Hospitalization 7/10/2012 72 Female 12/31/2012 Consumer Us
Primary
Concomitant
Pneumonia 4/13/2012 55 Female 128 lb 10/26/2012 Consumer Us
Primary
Concomitant
Injection Site Inflammation 7/13/2010 53 Female 113 lb 10/26/2012 Consumer Us
Primary
Concomitant
Arthropod Bite Male 196 lb 10/26/2012 Consumer Us
Primary
Concomitant
Bronchitis 8/6/2012 57 Female 220 lb 10/26/2012 Consumer Us
Primary
Concomitant
Injection Site Swelling 3/8/2012 64 Female 10/26/2012 Consumer Us
Primary
Concomitant
Ear Infection 3/1/2012 56 Female 200 lb 10/26/2012 Consumer Us
Primary
Concomitant
Vomiting 10/2012 71 Female 185 lb 10/29/2012 Consumer Us
Primary
Concomitant
Oropharyngeal Pain 10/11/2011 44 Female 220 lb 11/7/2012 Physician Us
Primary
Concomitant
Vertigo 2010 Male 176 lb 11/7/2012 Other Health Professional Us
Primary
Concomitant
Malaise 3/10/2006 52 Female 11/7/2012 Physician Us
Primary
Concomitant
Skin Discolouration 8/28/2011 51 Female 11/7/2012 Other Health Professional Us
Primary
Concomitant
Sinusitis 4/2012 Female 91 lb 11/8/2012 Physician Us
Primary
Concomitant
Injection Site Reaction 4/20/2012 65 Female 181 lb 11/8/2012 Physician Us
Primary
Concomitant
Tooth Infection Female 270 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Therapeutic Response Decreased 2/2012 58 Female 11/8/2012 Physician Us
Primary
Concomitant
Oral Herpes 4/1/2004 38 Female 193 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Herpes Zoster Female 11/8/2012 Physician Us
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2012 Male 218 lb 1/30/2013 Consumer Us
Primary
Concomitant
Urinary Tract Obstruction Other Serious 8/9/2012 65 Female 230 lb 11/21/2012 Consumer Country Not Specified
Primary
Concomitant
Hepatic Enzyme Increased 10/16/2012 46 Male 11/26/2012 Consumer Us
Primary
Concomitant
Walking Aid User Other Serious 2011 43 Female 12/3/2012 Consumer Us
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 2012 49 Female 143 lb 12/3/2012 Consumer Br
Primary
Concomitant
Wound Other Serious 2012 Male 12/3/2012 Physician Country Not Specified
Primary
Concomitant
Rectal Haemorrhage Other Serious Female 113 lb 3/20/2013 Physician Country Not Specified
Primary
Concomitant
Lung Infection Other Serious 2012 76 Female 110 lb 12/31/2012 Consumer Br
Primary
Concomitant
Ureteric Obstruction Other Serious 2010 74 Male 1/18/2013 Consumer Country Not Specified
Primary
Concomitant
Upper Limb Fracture 12/2011 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Viral Infection 4/7/2012 57 Female 167 lb 1/29/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Uveitis 2012 Male 153 lb 1/29/2013 Physician Us
Primary
Concomitant
Skin Discolouration 43 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Sinusitis NotSpecified 110 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Sneezing 6/30/2012 67 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Rheumatoid Arthritis 1/6/2012 47 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pain 12/14/2011 30 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Rheumatoid Arthritis 7/2011 76 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Urticaria 1/19/2012 60 Female 1/28/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/2010 Female 265 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Joint Swelling 2010 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pain 2/2/2012 50 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Tremor 67 Female 1/28/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 9/30/2011 Male 185 lb 9/12/2012 Physician De
Primary
Concomitant
Paraesthesia 76 Female 143 lb 10/29/2012 Physician Us
Primary
Concomitant
Gait Disturbance Other Serious 2011 67 Female 159 lb 10/30/2012 Consumer Br
Primary
Concomitant

Drug Data