Methotrexate combined with Pantoprazole Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancytopenia Hospitalization 61 Female 1/3/2006
Primary
Concomitant
Abdominal Abscess Hospitalization 11/8/2004 Female 148 lb 1/25/2006 Netherlands
Primary
Concomitant
Pregnancy Other Serious 12/28/2005 Female 146 lb 1/27/2006 Other Health Professional Austria
Primary
Concomitant
Pneumonia Legionella Hospitalization 1/1/2005 Male 119 lb 1/26/2006 Netherlands
Primary
Concomitant
Breast Microcalcification Other Serious 12/1/2005 Female 179 lb 2/17/2006 Consumer Canada
Primary
Concomitant
Weight Decreased Hospitalization 5/24/2005 83 Female 3/24/2006 Canada
Primary
Concomitant
Breast Microcalcification Other Serious 12/1/2005 Female 179 lb 4/13/2006 Physician Canada
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 1/1/2002 57 Male 179 lb 4/27/2006 Physician Germany
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 11/30/2005 85 Male 4/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Red Blood Cell Abnormality Hospitalization 11/30/2005 85 Male 4/26/2006 Other Health Professional France
Primary
Secondary
Pulmonary Oedema Hospitalization 2/3/2006 Male 210 lb 5/19/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Joint Reconstruction Other Serious 1/18/2006 Female 174 lb 5/22/2006 Consumer Canada
Primary
Concomitant
Weight Increased Hospitalization 12/1/2005 Female 201 lb 5/24/2006 Consumer Canada
Primary
Concomitant
Pancytopenia Hospitalization 61 Female 5/19/2006 Physician United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 1/1/2003 62 Female 7/13/2006 Consumer Australia
Primary
Concomitant
Lymphopenia Hospitalization 1/1/2006 33 Female 7/12/2006 Other Health Professional Austria
Primary
Concomitant
Weight Increased Hospitalization 12/14/2005 Female 201 lb 7/21/2006 Physician Canada
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/30/2006 54 Female 8/1/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Thyroid Neoplasm Life Threatening 4/21/2006 Female 167 lb 8/4/2006 Other Health Professional Canada
Primary
Concomitant
Syncope Hospitalization 1/1/2006 Female 156 lb 8/18/2006 Consumer United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 6/19/2006 65 Female 170 lb 9/5/2006 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 9/7/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2005 Female 180 lb 9/8/2006 Physician United States
Primary
Concomitant
Episcleritis Other Serious 7/1/2006 Female 134 lb 9/27/2006 Physician France
Primary
Concomitant
Renal Failure Other Serious 4/26/2006 Female 276 lb 10/3/2006 Physician Germany
Primary
Secondary
Concomitant
Vertigo Life Threatening 8/6/2005 Female 10/4/2006 Physician Finland
Primary
Concomitant
Vertigo Other Serious 8/6/2005 Female 10/4/2006 Physician Finland
Primary
Concomitant
Thrombocytopenia Other Serious 63 Male 273 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Skin Laceration Hospitalization 8/1/2006 Female 90 lb 11/2/2006 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 58 Male 11/1/2006 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2006 Female 160 lb 11/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Superior Sagittal Sinus Thrombosis Hospitalization 8/31/2006 Female 121 lb 12/18/2006 Pharmacist United States
Primary
Concomitant
Arthritis Bacterial Other Serious 12/20/2006 68 Female 1/4/2007 Consumer Argentina
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Arthritis Other Serious 12/20/2006 68 Female 1/11/2007 Consumer Argentina
Primary
Secondary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Hypertension Hospitalization 4/12/2006 Female 1/16/2007 Other Health Professional Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 12/12/2005 63 Male 273 lb 2/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 2/6/2006 Female 2/2/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/1/2005 Male 141 lb 2/9/2007 Physician Belgium
Primary
Concomitant
Vomiting Other Serious 10/16/2003 Female 121 lb 2/12/2007 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 10/25/2006 70 Female 2/13/2007 Other Health Professional Canada
Primary
Concomitant
Coeliac Disease Other Serious 1/18/2007 Female 94 lb 2/15/2007 Physician Canada
Primary
Concomitant
Wound Necrosis Hospitalization 7/10/2006 Female 2/16/2007 Physician Belgium
Primary
Concomitant
Vomiting Other Serious 10/16/2003 Female 121 lb 2/16/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/1/2005 Male 141 lb 2/21/2007 Physician Belgium
Primary
Concomitant
Vasculitis Necrotising Hospitalization 2/10/2007 69 Female 211 lb 3/6/2007 Physician Austria
Primary
Secondary
Concomitant
Vasculitis Necrotising Hospitalization 2/10/2007 69 Female 211 lb 3/16/2007 Physician Austria
Primary
Secondary
Concomitant
Thymus Enlargement Hospitalization 1/1/2005 Female 118 lb 3/16/2007 Physician Canada
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 12/1/2006 82 Female 112 lb 3/23/2007 Other Health Professional Canada
Primary
Concomitant
Arthropathy Hospitalization Female 200 lb 3/28/2007 Consumer Canada
Primary
Concomitant
Thrombocytopenia Other Serious 12/12/2005 63 Male 273 lb 3/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Thymus Enlargement Hospitalization 1/1/2005 Female 118 lb 4/2/2007 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 12/19/2006 Female 141 lb 4/5/2007 Belgium
Primary
Concomitant
Thrombocytopenia Hospitalization 12/19/2006 Female 141 lb 4/18/2007 Belgium
Primary
Concomitant
Drug Ineffective Hospitalization Female 140 lb 4/25/2007 Consumer Canada
Primary
Concomitant
Pain In Extremity Other Serious 10/25/2006 Female 5/2/2007 Other Health Professional Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/3/2006 Female 172 lb 5/3/2007 Physician Austria
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 12/1/2006 Female 112 lb 5/9/2007 Other Health Professional Canada
Primary
Concomitant
Gastroenteritis Other Serious 4/8/2007 Male 5/10/2007 Physician United Kingdom
Primary
Concomitant
Metastatic Renal Cell Carcinoma Other Serious 1/1/1999 Female 141 lb 5/18/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/20/2007 Female 132 lb 5/18/2007 Consumer United Kingdom
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 2/11/2007 65 Male 157 lb 5/14/2007 Physician France
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 2/11/2007 65 Male 157 lb 5/17/2007 Physician France
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 6/8/2007 Physician Italy
Primary
Concomitant
Respiratory Failure Other Serious 62 Female 6/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 62 Female 6/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 2/11/2007 65 Male 157 lb 6/18/2007 Physician France
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 6/18/2007 Female 190 lb 6/28/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 5/28/2007 Female 155 lb 6/29/2007 Consumer Canada
Primary
Concomitant
Interacting
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 7/5/2007 Physician Italy
Primary
Concomitant
Respiratory Failure Other Serious 62 Female 7/13/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/1/2007 Female 118 lb 7/19/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Psoriasis Hospitalization 6/1/2007 59 Female 7/20/2007 Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 4/1/2007 32 Female 165 lb 7/20/2007 Consumer Brazil
Primary
Concomitant
Incision Site Infection Hospitalization Female 130 lb 7/23/2007 Canada
Primary
Concomitant
Tibia Fracture Hospitalization 4/1/2006 76 Female 8/14/2007 Germany
Primary
Concomitant
Temperature Intolerance Other Serious 10/1/2006 Female 159 lb 8/20/2007 Other Health Professional Canada
Primary
Concomitant
Tongue Haemorrhage Hospitalization 2/11/2007 65 Male 157 lb 8/21/2007 Physician France
Primary
Secondary
Concomitant
Polyp Other Serious 6/1/2007 Female 154 lb 8/24/2007 Canada
Primary
Concomitant
Staphylococcal Infection Other Serious 7/7/2007 Female 137 lb 8/30/2007 Germany
Primary
Concomitant
Pneumocystis Jiroveci Infection Hospitalization 4/24/2007 Male 9/4/2007 Physician Finland
Primary
Concomitant
Road Traffic Accident Hospitalization 8/14/2007 Female 9/4/2007 United States
Primary
Concomitant
Joint Dislocation Other Serious 8/24/2007 Female 154 lb 9/5/2007 Canada
Primary
Concomitant
Renal Failure Hospitalization 3/1/2007 Female 118 lb 9/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Drainage Hospitalization 9/10/2007 Male 160 lb 9/20/2007 Canada
Primary
Concomitant
Wound Drainage Hospitalization 9/10/2007 Male 160 lb 9/26/2007 Canada
Primary
Concomitant
Renal Failure Life Threatening 8/16/2007 Male 9/27/2007 Australia
Primary
Concomitant
Stress Fracture Other Serious 12/1/2006 50 Female 140 lb 10/2/2007 Pharmacist Canada
Primary
Concomitant
Wound Drainage Hospitalization 9/10/2007 Male 160 lb 10/11/2007 Canada
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/1/2007 71 Female 10/16/2007 Physician Canada
Primary
Concomitant
Interacting
Haemoglobin Decreased Other Serious 4/1/2007 71 Female 10/18/2007 Physician Canada
Primary
Concomitant
Interacting
Alveolitis Fibrosing Life Threatening 61 Female 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 3/1/2004 Female 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 7/2/2007 Female 176 lb 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Urosepsis Other Serious 10/1/2007 Female 11/20/2007 Other Health Professional Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/21/2007 Female 11/21/2007 Belgium
Primary
Concomitant
Hypertension Hospitalization 6/11/2004 Female 11/21/2007 Germany
Primary
Concomitant
Steroid Therapy Life Threatening 4/1/2007 Female 132 lb 11/21/2007 Physician Netherlands
Primary
Concomitant
Arthropathy Hospitalization 9/19/2005 60 Female 11/29/2007 Physician Austria
Primary
Concomitant
Renal Failure Hospitalization 7/9/2007 Male 11/30/2007 Australia
Primary
Concomitant
Testicular Cyst Other Serious 7/27/2006 Male 230 lb 12/3/2007 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious Female 80 lb 12/7/2007 Canada
Primary
Concomitant
Pneumonitis Hospitalization 2/11/2007 65 Male 157 lb 12/6/2007 Physician France
Primary
Secondary
Concomitant
Injection Site Irritation 6/1/2007 Female 165 lb 12/14/2007 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 8/1/2007 Female 226 lb 12/14/2007 Physician United States
Primary
Concomitant
Drug Ineffective 9/1/2007 Female 200 lb 12/14/2007 Consumer United States
Primary
Concomitant
Injury 9/24/2007 Female 152 lb 12/14/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness 7/1/2007 Female 150 lb 12/14/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral 11/10/2007 Female 230 lb 12/15/2007 United States
Primary
Concomitant
Skin Cancer Other Serious 11/2/2005 Female 132 lb 12/19/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious Female 80 lb 12/20/2007 Canada
Primary
Concomitant
Renal Failure Hospitalization 7/5/2007 Male 12/20/2007 Australia
Primary
Concomitant
Pain In Extremity Hospitalization 5/6/2007 55 Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 12/2/2007 Male 219 lb 12/21/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious Female 80 lb 1/17/2008 Canada
Primary
Concomitant
Rectosigmoid Cancer Other Serious 4/1/2007 Female 1/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 4/1/2006 76 Female 2/8/2008 Germany
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 9/24/2005 Male 143 lb 2/27/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Opportunistic Infection Hospitalization 2/11/2007 65 Male 157 lb 2/20/2008 Physician France
Primary
Secondary
Concomitant
Restlessness Hospitalization Female 3/5/2008 Germany
Primary
Concomitant
White Blood Cell Count Increased 9/22/2006 Female 180 lb 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/5/2005 Female 133 lb 3/14/2008 United States
Primary
Concomitant
Musculoskeletal Stiffness 7/1/2007 Female 155 lb 3/14/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 12/10/2007 Female 152 lb 3/14/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 1/4/2008 Female 230 lb 3/15/2008 Consumer United States
Primary
Concomitant
Skin Lesion 2/6/2008 Female 155 lb 3/15/2008 United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2008 Male 178 lb 3/15/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/18/2008 74 Female 112 lb 3/18/2008 Physician
Primary
Concomitant
Lymphadenitis Other Serious 9/26/2007 Female 190 lb 3/21/2008 Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/18/2008 74 Female 3/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sensory Disturbance Hospitalization 2/4/2008 Male 148 lb 3/27/2008 Physician Netherlands
Primary
Concomitant
Haematochezia Other Serious 1/1/2008 70 Female 141 lb 3/28/2008 Other Health Professional Canada
Primary
Concomitant
Wheezing Other Serious 2/14/2008 Female 76 lb 3/28/2008 Canada
Primary
Concomitant
Mucous Stools Hospitalization 11/6/2007 Female 4/16/2008 Other Health Professional France
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 4/16/2008 Physician Italy
Primary
Concomitant
Dyspnoea Other Serious 2/4/2008 Female 254 lb 4/17/2008 Physician United States
Primary
Concomitant
Mucous Stools Hospitalization 6/11/2007 Female 4/23/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/7/2007 Female 137 lb 4/25/2008 Germany
Primary
Secondary
Concomitant
Erythema Nodosum Other Serious 7/1/2007 Female 148 lb 4/28/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2006 Female 168 lb 4/30/2008 France
Primary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 168 lb 5/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 167 lb 4/25/2008 United States
Primary
Secondary
Concomitant
Injection Site Swelling Other Serious 3/12/2008 Female 155 lb 5/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Other Serious 12/1/2007 Female 5/9/2008 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/2/2007 Female 176 lb 5/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2006 Female 168 lb 5/13/2008 France
Primary
Concomitant

Drug Data