Enalapril Maleate combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Von Willebrand's Factor Multimers Abnormal Other Serious 8/1/2005 57 Female 150 lb 12/30/2005 Argentina
Primary
Concomitant
Musculoskeletal Stiffness Disability 11/30/2005 Female 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 9/1/2001 Female 159 lb 3/27/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Breast Cancer Female Life Threatening Female 3/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Peritonitis Hospitalization 10/1/2005 Female 4/5/2006 Consumer Australia
Primary
Concomitant
Coronary Artery Occlusion Other Serious 2/20/2006 Female 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 9/18/2005 58 Male 4/13/2006 Physician Germany
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 4/20/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/17/2006 60 Female 5/3/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Diverticular Perforation Other Serious 4/7/2004 Female 132 lb 5/11/2006 Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 4/1/2006 Male 220 lb 5/26/2006 Physician Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/27/2006 61 Female 165 lb 6/28/2006 Physician Argentina
Primary
Concomitant
Eye Inflammation Other Serious 3/1/2006 Female 6/15/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/27/2006 61 Female 165 lb 9/8/2006 Physician Argentina
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/1/2006 73 Female 9/18/2006 Consumer United States
Primary
Concomitant
Bronchospasm Hospitalization 11/25/2005 36 Male 10/6/2006 Physician Germany
Primary
Concomitant
Pneumonia Aspiration Hospitalization 1/1/2002 73 Female 10/11/2006 Consumer United States
Primary
Concomitant
Pulmonary Granuloma Life Threatening 1/1/2006 40 Male 10/25/2006 Physician Iceland
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 31 Female 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2005 Female 107 lb 11/8/2006 Consumer Brazil
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/27/2006 61 Female 165 lb 11/17/2006 Physician Argentina
Primary
Concomitant
Diverticular Perforation Other Serious 4/7/2004 Female 132 lb 12/1/2006 Germany
Primary
Concomitant
Osteomyelitis Acute Hospitalization 9/8/2006 49 Female 12/6/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Sarcoidosis Life Threatening 1/1/2006 40 Male 11/27/2006 Physician Switzerland
Primary
Secondary
Concomitant
Renal Artery Stent Placement Hospitalization 5/1/2006 Female 157 lb 12/8/2006 Physician United States
Primary
Concomitant
Spinal Fracture Hospitalization 1/13/2005 Female 159 lb 12/15/2006 Consumer United Kingdom
Primary
Concomitant
Malaise 2/9/2006 Female 12/21/2006 Other Health Professional United States
Primary
Concomitant
Urine Ketone Body Present Other Serious 12/1/2005 Female 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Femur Fracture Other Serious 8/17/2004 Female 159 lb 1/9/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/25/2006 Female 139 lb 1/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Dislocation Other Serious 8/6/2003 Female 123 lb 2/1/2007 Consumer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/3/2007 53 Male 179 lb 2/12/2007 Physician Israel
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 7/4/2005 Female 159 lb 2/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/16/2006 Male 198 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pericarditis Hospitalization 2/18/2007 42 Male 317 lb 3/7/2007 Physician Greece
Primary
Concomitant
Respiratory Failure Hospitalization 88 Female 3/19/2007 Physician United States
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 12/1/2005 Female 3/21/2007 Physician Sweden
Primary
Concomitant
Joint Swelling Other Serious 11/1/2006 61 Female 269 lb 3/23/2007 United Kingdom
Primary
Secondary
Concomitant
Joint Swelling Required Intervention 11/1/2006 61 Female 3/26/2007 United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Metrorrhagia Other Serious 1/1/2005 60 Female 4/12/2007 Other Health Professional France
Primary
Concomitant
Basal Cell Carcinoma Other Serious 11/15/2003 Female 4/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Dislocation Hospitalization 53 Female 121 lb 5/29/2007 Consumer Brazil
Primary
Concomitant
Cholecystitis Hospitalization 2/5/2007 54 Female 5/30/2007 Consumer Poland
Primary
Concomitant
Sudden Death Death 4/29/2007 79 Female 154 lb 5/24/2007 Netherlands
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/19/2006 Male 130 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/20/2007 Consumer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 2/1/2007 60 Female 176 lb 8/3/2007 Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 12/13/2006 55 Female 6/8/2007 Consumer United States
Primary
Concomitant
Gastric Ulcer Death 8/1/2007 Male 205 lb 10/4/2007 Physician Poland
Primary
Concomitant
Urine Analysis Abnormal Other Serious 53 Male 11/13/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Hypertension Hospitalization 6/11/2004 Female 11/21/2007 Germany
Primary
Concomitant
Venous Thrombosis Other Serious 53 Male 12/7/2007 Physician Portugal
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 10/1/2006 Female 146 lb 12/14/2007 Other Health Professional United States
Primary
Concomitant
Angioedema Hospitalization 7/13/2007 44 12/27/2007 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Death 12/26/2007 Female 254 lb 1/14/2008 Other Health Professional United States
Primary
Concomitant
Schizophrenia Other Serious 12/21/2004 46 Male 140 lb 12/6/2007 United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2005 Female 107 lb 1/21/2008 Consumer Brazil
Primary
Concomitant
Interacting
Palpitations Hospitalization 3/1/2005 66 Male 1/29/2008 Physician Sweden
Primary
Concomitant
Nausea Other Serious 8/1/2007 76 Female 148 lb 2/19/2008 Physician Brazil
Primary
Concomitant
Staphylococcal Infection Hospitalization 7/17/2007 Female 143 lb 2/29/2008 United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/1/2007 60 Male 3/1/2008 Physician Sweden
Primary
Secondary
Concomitant
Faeces Discoloured Other Serious 8/1/2007 87 Female 128 lb 8/17/2007 Consumer United States
Primary
Secondary
Concomitant
Inappropriate Schedule Of Drug Administration 8/23/2006 Female 3/14/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 12/28/2007 Female 104 lb 3/14/2008 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 1/15/2008 47 Female 172 lb 3/20/2008 Physician Germany
Primary
Concomitant
Faeces Discoloured Other Serious 8/16/2007 87 Female 128 lb 3/3/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Hospitalization 6/14/2007 Female 143 lb 4/11/2008 United Kingdom
Primary
Secondary
Concomitant
Alveolitis Allergic Other Serious 3/26/2008 Male 161 lb 4/21/2008 Argentina
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/15/2008 47 Female 172 lb 5/12/2008 Physician Germany
Primary
Concomitant
Wound Secretion Other Serious 9/2/2005 Male 5/21/2008 Physician United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 1/15/2008 47 Female 172 lb 5/22/2008 Other Health Professional Germany
Primary
Concomitant
Fatigue 1/1/2008 Female 170 lb 6/12/2008 United States
Primary
Concomitant
Sepsis Life Threatening 5/11/2008 Female 199 lb 6/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/11/2008 61 Female 199 lb 7/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 53 Male 7/16/2008 Other Health Professional Portugal
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/1/2007 60 Male 7/16/2008 Physician Sweden
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 1/1/2004 67 Female 7/18/2008 Consumer Mexico
Primary
Concomitant
Blood Glucose Decreased Hospitalization 11/1/2006 81 Female 7/24/2008 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 2/1/2007 67 Female 7/29/2008 Consumer Mexico
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/2/2008 Female 8/4/2008 Physician United States
Primary
Concomitant
Alveolitis Allergic Other Serious 3/26/2008 Male 161 lb 8/7/2008 Argentina
Primary
Secondary
Concomitant
Swelling Face 5/12/2008 Female 249 lb 8/27/2008 Other Health Professional United States
Primary
Concomitant
Paraesthesia 7/1/2008 Female 8/29/2008 United States
Primary
Concomitant
Haematemesis Hospitalization 11/3/2002 Male 254 lb 9/4/2008 United Kingdom
Primary
Concomitant
Pyrexia Life Threatening 8/16/2008 Female 103 lb 9/5/2008 United States
Primary
Concomitant
Haematemesis Hospitalization 11/3/2007 Male 254 lb 9/8/2008 United Kingdom
Primary
Concomitant
Procedural Complication 8/11/2008 Male 250 lb 9/13/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 4/1/2008 Female 265 lb 9/13/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 8/16/2008 Female 103 lb 9/26/2008 United States
Primary
Concomitant
B-cell Lymphoma Required Intervention 8/19/2008 Female 185 lb 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 72 Female 4/17/2008 Netherlands
Primary
Concomitant
Renal Impairment Death 5/25/2008 Female 134 lb 10/24/2008 United Kingdom
Primary
Concomitant
Renal Impairment Death 5/25/2008 Female 134 lb 10/24/2008 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/2/2008 Female 10/27/2008 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 5/15/2008 Male 205 lb 10/29/2008 United Kingdom
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 5/15/2008 Male 205 lb 10/31/2008 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2007 Female 11/3/2008 Physician United States
Primary
Concomitant
Stress Fracture Hospitalization 64 Female 11/7/2008 Netherlands
Primary
Concomitant
Melaena Hospitalization 2/13/2008 61 Female 234 lb 11/11/2008 Pharmacist United States
Primary
Concomitant
Stress Fracture Hospitalization 64 Female 11/19/2008 Netherlands
Primary
Concomitant
Urinary Tract Infection Life Threatening 8/16/2008 Female 103 lb 11/21/2008 United States
Primary
Concomitant
Alveolitis Allergic Other Serious 3/26/2008 Male 161 lb 11/21/2008 Argentina
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 54 Male 11/24/2008 Physician Spain
Primary
Secondary
Concomitant
Pyrexia 10/1/2007 Female 170 lb 12/12/2008 Puerto Rico
Primary
Concomitant
Procedural Complication 8/11/2008 Male 250 lb 12/12/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection 9/19/2008 Female 195 lb 12/12/2008 United States
Primary
Concomitant
Urticaria 10/15/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Psoriasis 1/1/2008 Female 12/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 11/6/2008 Female 180 lb 12/12/2008 United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2003 Female 12/18/2008 Physician United States
Primary
Concomitant
Alveolitis Allergic Other Serious 3/26/2008 Male 161 lb 12/19/2008 Argentina
Primary
Secondary
Concomitant
Kaposi's Sarcoma Other Serious 11/1/2008 77 Male 12/29/2008 Physician Canada
Primary
Concomitant
Meningitis Life Threatening 12/24/2008 Female 1/6/2009 Physician Russian Federation
Primary
Concomitant
Sciatica Other Serious 5/1/2005 Female 180 lb 1/13/2009 Consumer United States
Primary
Concomitant
Kaposi's Sarcoma Other Serious 11/1/2008 77 Male 1/16/2009 Physician Canada
Primary
Concomitant
Rhabdomyolysis Other Serious 54 Male 1/30/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Fall Other Serious 9/7/2008 Female 2/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hyperthyroidism Other Serious 9/12/2008 67 Female 2/9/2009 Other Health Professional Sweden
Primary
Concomitant
Urinary Tract Infection Life Threatening 10/29/2002 Female 3/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Thyroid Haemorrhage Hospitalization 9/8/2008 74 Female 3/11/2009 Physician Germany
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 3/25/2009 Physician Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 54 Male 5/4/2009 Spain
Primary
Concomitant
Interacting
Syncope Other Serious 4/29/2009 Female 5/5/2009 Brazil
Primary
Concomitant
Uterine Haemorrhage Hospitalization 1/8/2009 Female 161 lb 5/6/2009 Physician Mexico
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 54 Male 5/8/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 54 Male 5/11/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Malaise Hospitalization 3/1/2009 Female 5/11/2009 Consumer Argentina
Primary
Concomitant
Hepatitis Other Serious 48 Female 5/8/2009 Consumer Colombia
Primary
Concomitant
Rhabdomyolysis Other Serious 57 Male 5/8/2009 Physician Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 68 Female 161 lb 5/21/2009 Physician Brazil
Primary
Concomitant
Renal Impairment Other Serious 3/21/2009 58 5/22/2009 Physician Costa Rica
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/6/2009 Female 196 lb 5/22/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 54 Male 5/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Hepatitis Other Serious 48 Female 5/20/2009 Consumer Colombia
Primary
Concomitant
Stomatitis Other Serious 1/1/2007 54 Male 5/22/2009 Physician Spain
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 4/21/2009 Female 189 lb 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/15/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Renal Failure Life Threatening 56 Male 7/16/2009 Australia
Primary
Secondary
Concomitant
Uterine Haemorrhage Hospitalization 1/8/2009 Female 161 lb 7/16/2009 Physician Mexico
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 6/18/2009 Female 112 lb 7/20/2009 Other Health Professional Argentina
Primary
Secondary
Concomitant
Viral Infection Hospitalization 6/1/2009 62 Female 220 lb 7/21/2009 Other Health Professional Austria
Primary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/21/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Hypotension Hospitalization 9/8/2008 74 Female 150 lb 7/27/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 7/30/2009 Physician Costa Rica
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 8/3/2009 Physician Costa Rica
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/6/2009 Female 196 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 Male 274 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 6/9/2009 Female 189 lb 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Acute Prerenal Failure Hospitalization 1/1/2008 55 Female 8/18/2009 Physician Spain
Primary
Interacting

Drug Data