Methotrexate combined with Speciafoldine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 12/13/2005 43 Male 123 lb 1/12/2006 Physician France
Primary
Concomitant
Thrombocytopenia Hospitalization 11/10/2005 79 Female 1/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/10/2005 79 Female 1/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/13/2005 43 Male 123 lb 1/24/2006 Physician France
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2003 65 Female 2/17/2006 Physician France
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 12/1/2005 Male 198 lb 2/22/2006 Physician France
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/11/2006 77 Female 2/24/2006 Physician France
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/7/2006 28 Male 123 lb 3/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/25/2006 28 Male 123 lb 3/24/2006 France
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 12/1/2005 69 Male 198 lb 4/13/2006 Physician France
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2003 65 Female 5/11/2006 Physician France
Primary
Secondary
Concomitant
Tremor Hospitalization 3/24/2006 43 Female 123 lb 5/12/2006 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 40 Female 5/19/2006 Consumer Japan
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Death 12/5/2005 80 Male 154 lb 5/23/2006
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 12/1/2005 69 Male 198 lb 6/1/2006 Physician France
Primary
Concomitant
Thrombocytopenia Hospitalization 12/5/2005 80 Male 154 lb 6/7/2006
Primary
Concomitant
Tremor Hospitalization 3/24/2006 43 Female 123 lb 6/22/2006 Physician France
Primary
Concomitant
Drug Exposure Before Pregnancy Other Serious 5/22/2006 Female 115 lb 6/26/2006 Physician France
Primary
Secondary
Shock Hospitalization 1/1/2004 53 Female 6/29/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pregnancy Other Serious 3/25/2006 22 Female 6/24/2006 Other Health Professional France
Primary
Secondary
Lymph Node Tuberculosis Other Serious 12/1/2005 69 Male 198 lb 7/7/2006 Physician France
Primary
Concomitant
Mycobacterium Chelonei Infection Hospitalization 5/5/2006 62 Male 168 lb 7/20/2006 Physician France
Primary
Concomitant
Stomach Granuloma Hospitalization 3/20/2006 23 Female 7/20/2006 Other Health Professional France
Primary
Concomitant
Interacting
Pneumonia Streptococcal Other Serious 12/8/2005 36 Male 165 lb 8/3/2006 Physician France
Primary
Secondary
Concomitant
Pregnancy Other Serious 5/22/2006 Female 115 lb 8/14/2006 Physician France
Primary
Secondary
Urinary Tract Infection Hospitalization 8/1/2005 62 Male 168 lb 8/14/2006 Physician France
Primary
Concomitant
Pregnancy Other Serious 3/28/2006 22 Female 8/10/2006 Other Health Professional France
Primary
Secondary
Pneumonia Streptococcal Other Serious 12/8/2005 36 Male 165 lb 8/21/2006 Physician France
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 6/21/2006 55 Female 8/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
Lymphoma Life Threatening 7/17/2006 56 Female 8/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2005 62 Male 168 lb 8/29/2006 Physician France
Primary
Secondary
Concomitant
Septic Shock Death 9/1/2005 37 Female 141 lb 9/28/2006 Physician France
Primary
Concomitant
Progesterone Receptor Assay Positive Hospitalization 3/6/2006 Female 209 lb 10/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 6/21/2006 55 Female 10/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 10/21/2006 Female 11/3/2006 Consumer France
Primary
Concomitant
Lymph Node Tuberculosis Hospitalization 10/9/2005 41 Female 11/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 6/21/2006 55 Female 11/29/2006 Other Health Professional France
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 9/22/2006 44 Male 165 lb 12/15/2006 Other Health Professional France
Primary
Concomitant
Thyroid Cancer Hospitalization 1/1/2006 56 Female 12/21/2006 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 8/30/2006 Male 176 lb 12/22/2006 Physician France
Primary
Secondary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 2/1/2006 71 Male 196 lb 12/29/2006 Physician France
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 11/28/2006 55 Female 176 lb 1/18/2007 Physician France
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 11/21/2006 Male 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
B-cell Small Lymphocytic Lymphoma Hospitalization 64 Male 2/20/2007 Other Health Professional France
Primary
Secondary
Concomitant
Rheumatoid Arthritis Life Threatening 6/1/2006 51 Female 115 lb 2/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 12/8/2006 83 Female 3/8/2007 Consumer France
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 12/18/2006 48 Female 143 lb 4/6/2007 Physician France
Primary
Concomitant
Squamous Cell Carcinoma Life Threatening 3/12/2007 58 Female 139 lb 4/24/2007
Primary
Secondary
Status Epilepticus Life Threatening 3/22/2007 42 Male 5/3/2007 Consumer United States
Primary
Secondary
Concomitant
Cryptogenic Organising Pneumonia Other Serious Female 150 lb 5/18/2007 Physician United Kingdom
Primary
Concomitant
Pruritus Other Serious 4/12/2007 45 Female 132 lb 6/15/2007 Physician France
Primary
Concomitant
Cryptogenic Organising Pneumonia Hospitalization 4/1/2007 Female 150 lb 6/15/2007 Physician United Kingdom
Primary
Concomitant
Death Death 9/1/2006 73 Female 6/15/2007 Physician France
Primary
Concomitant
Vomiting Hospitalization 5/24/2007 36 Male 6/27/2007 Other Health Professional France
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 7/2/2007 Female 176 lb 7/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vertigo Other Serious 2/9/2007 Female 166 lb 7/17/2007 Consumer United Kingdom
Primary
Concomitant
Tremor Other Serious 5/18/2007 57 Female 150 lb 7/20/2007 Physician France
Primary
Concomitant
Vitreous Detachment Disability 3/10/2007 Female 7/25/2007 Physician France
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 5/9/2007 58 Female 9/7/2007 Other Health Professional France
Primary
Concomitant
Pharyngitis Streptococcal Hospitalization 9/17/2007 50 Male 9/27/2007 Physician France
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 7/3/2007 58 Male 161 lb 9/28/2007 Physician France
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2007 79 Female 121 lb 9/25/2007 Physician
Primary
Concomitant
Post Procedural Infection Hospitalization 54 Female 170 lb 10/23/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pharyngitis Streptococcal Hospitalization 9/17/2007 50 Male 11/13/2007 Physician France
Primary
Secondary
Concomitant
Tuberculosis Other Serious 5/12/2001 Male 132 lb 11/13/2007 Other Health Professional France
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 7/2/2007 Female 176 lb 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Bronchitis Hospitalization 12/30/2005 71 Female 11/16/2007 Other Health Professional France
Primary
Concomitant
Pharyngitis Streptococcal Hospitalization 9/16/2007 Male 11/29/2007 Physician France
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 11/29/2007 Consumer France
Primary
Secondary
Concomitant
Eosinophilia Other Serious 3/4/1999 53 Female 11/27/2007 France
Primary
Concomitant
Sciatica Hospitalization 8/1/2007 56 Female 227 lb 12/7/2007 Other Health Professional France
Primary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 12/8/2007 Consumer France
Primary
Secondary
Concomitant
Tuberculosis Other Serious 5/12/2001 Male 132 lb 12/10/2007 Other Health Professional France
Primary
Concomitant
Pyelonephritis Hospitalization 7/2/2007 Female 176 lb 12/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/1/2007 Female 106 lb 12/17/2007 Physician France
Primary
Secondary
Concomitant
Pseudomonal Sepsis Hospitalization 79 Female 1/15/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/1/2007 33 Female 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Hospitalization Female 1/31/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/1/2007 33 Female 2/5/2008 Consumer United States
Primary
Secondary
Concomitant
Demyelination Other Serious 10/15/2007 Male 137 lb 2/21/2008 Physician France
Primary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 2/26/2008 Consumer France
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/19/2008 71 Female 148 lb 3/12/2008 Physician France
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/1/2008 74 Female 220 lb 3/24/2008 Pharmacist France
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 1/1/2008 74 Female 220 lb 4/11/2008 Pharmacist France
Primary
Secondary
Concomitant
Hypertension Hospitalization 3/1/2007 51 Male 4/15/2008 Other Health Professional France
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 1/1/2008 Female 4/23/2008 Physician France
Primary
Concomitant
Humerus Fracture Hospitalization 4/4/2008 62 Female 139 lb 10/10/2008 Physician France
Primary
Concomitant
Dyspnoea Hospitalization 9/1/2008 65 Female 10/14/2008 Physician France
Primary
Concomitant
Vomiting Hospitalization 6/10/2008 Female 10/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/1/2005 42 Male 10/23/2008 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/30/2008 42 Female 10/28/2008 Other Health Professional France
Primary
Concomitant
Waldenstrom's Macroglobulinaemia Other Serious 2/1/2008 Female 154 lb 10/31/2008 Physician France
Primary
Secondary
Concomitant
Bladder Cancer Hospitalization 6/20/2008 Male 11/25/2008 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/15/2008 Female 11/26/2008 Other Health Professional France
Primary
Secondary
Concomitant
Type Iii Immune Complex Mediated Reaction Hospitalization 5/1/2007 36 Male 12/1/2008 Other Health Professional France
Primary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 12/5/2008 Consumer France
Primary
Secondary
Concomitant
Waldenstrom's Macroglobulinaemia Life Threatening 9/1/2006 Female 176 lb 12/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Cyst Other Serious 8/22/2008 80 Male 12/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 9/5/2008 Female 1/23/2009 Other Health Professional France
Primary
Concomitant
Rhabdomyolysis Other Serious 5/1/2008 1/23/2009 France
Primary
Concomitant
Interacting
Rectal Haemorrhage Other Serious 10/16/2008 70 Male 1/26/2009 Physician France
Primary
Secondary
Concomitant
Hepatic Neoplasm Life Threatening 4/1/2008 Male 220 lb 2/2/2009 France
Primary
Concomitant
Hypersensitivity Other Serious 9/7/2008 Male 2/6/2009 Physician France
Primary
Concomitant
Vasculitis Other Serious 12/8/2008 56 Female 97 lb 2/9/2009 Physician France
Primary
Concomitant
Productive Cough Hospitalization 11/1/2008 Female 2/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 1/1/2009 Female 2/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 1/1/2009 Female 2/18/2009 Other Health Professional France
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 1/1/2009 Female 2/18/2009 Other Health Professional France
Primary
Secondary
Concomitant
Lymphangitis Hospitalization 8/3/2002 Male 181 lb 2/20/2009 France
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 1/1/2009 Female 2/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Sudden Death Death 1/1/2009 61 Male 3/16/2009 Physician France
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 59 Female 3/16/2009 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 11/9/2008 85 Female 3/19/2009 Other Health Professional France
Primary
Secondary
Concomitant
Gastric Cancer Hospitalization 8/26/2008 57 Female 3/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious 1/5/2008 28 Female 99 lb 3/27/2009 Physician France
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious 1/5/2008 28 Female 99 lb 3/30/2009 Physician France
Primary
Secondary
Concomitant
Injection Site Cellulitis Hospitalization 8/3/2002 Male 181 lb 3/31/2009 France
Primary
Concomitant
Vomiting Other Serious 11/9/2008 85 Female 4/21/2009 Other Health Professional France
Primary
Secondary
Concomitant
Wound Life Threatening 12/15/2008 Female 4/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Night Sweats Hospitalization 1/1/2009 Female 4/29/2009 Other Health Professional France
Primary
Concomitant
Osteoarthritis Other Serious 3/1/2006 Female 143 lb 5/18/2009 Consumer United Kingdom
Primary
Concomitant
Tenosynovitis Hospitalization 4/1/2007 Female 100 lb 5/26/2009 Physician United Kingdom
Primary
Concomitant
Pleurisy Other Serious 10/29/2008 74 Female 194 lb 6/16/2009 Physician France
Primary
Concomitant
Lung Disorder Hospitalization 12/20/2006 Female 117 lb 6/17/2009 France
Primary
Concomitant
Vertigo Other Serious 2/9/2007 Female 166 lb 6/30/2009 Consumer United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2009 73 Female 7/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vertigo Other Serious 2/9/2007 Female 166 lb 7/15/2009 Consumer United Kingdom
Primary
Concomitant
Lymphoma Life Threatening 7/17/2006 56 Female 7/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Muscle Haemorrhage Hospitalization 3/18/2007 Female 43 lb 7/27/2009 Consumer United Kingdom
Primary
Concomitant
Muscle Haemorrhage Hospitalization 3/18/2007 Female 43 lb 8/4/2009 Consumer United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2009 Female 110 lb 8/25/2009 Other Health Professional France
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 7/15/2009 Female 143 lb 8/26/2009 Consumer United Kingdom
Primary
Concomitant
Muscle Haemorrhage Hospitalization 3/18/2007 Female 43 lb 9/23/2009 Consumer United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 8/23/2009 71 Female 9/24/2009
Primary
Concomitant
Hepatic Neoplasm Life Threatening 4/7/2008 Male 220 lb 9/25/2009 France
Primary
Concomitant
Vasculitis Hospitalization 4/8/2008 Male 163 lb 9/28/2009 Consumer France
Primary
Concomitant
Skin Ulcer Other Serious 7/1/2009 70 Female 9/30/2009 Physician France
Primary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 2/1/2006 71 Male 196 lb 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lymphocytosis Other Serious 9/1/2009 Male 201 lb 10/7/2009 Physician France
Primary
Secondary
Concomitant
Sigmoiditis Other Serious 5/6/2009 58 Male 10/13/2009 Physician France
Primary
Concomitant
Hepatitis B Other Serious 9/1/2009 Male 10/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis B Other Serious 9/1/2009 Male 10/20/2009 Consumer United Kingdom
Primary
Concomitant
Pyrexia Other Serious 12/13/2006 Female 137 lb 10/23/2009 Consumer France
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/13/2006 Female 137 lb 10/29/2009 Consumer France
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 6/21/2006 55 Female 10/30/2009 Other Health Professional France
Primary
Secondary
Concomitant
Psoriasis Hospitalization 1/1/2008 53 Male 254 lb 11/5/2009 Physician France
Primary
Concomitant
Psoriasis Hospitalization 1/1/2008 53 Male 254 lb 11/9/2009 Physician France
Primary
Concomitant
Psoriasis Hospitalization 1/1/2008 53 Male 254 lb 11/17/2009 Physician France
Primary
Concomitant
Pleurisy Other Serious 10/29/2008 74 Female 194 lb 12/1/2009 Physician France
Primary
Concomitant
Epilepsy Hospitalization Female 12/18/2009 Physician United Kingdom
Primary
Concomitant

Drug Data