Carvedilol combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vasculitis Death 9/27/2005 Female 214 lb 2/7/2006 Italy
Primary
Concomitant
Vasculitis Death 9/27/2005 Female 214 lb 4/18/2006 Other Health Professional Italy
Primary
Concomitant
Septic Shock Hospitalization 70 Male 6/7/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Stomatitis Hospitalization 70 Male 7/7/2006
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/14/2006 Pharmacist Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/7/2005 83 Male 165 lb 7/17/2006 Denmark
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/9/2006 Female 200 lb 3/22/2007 Other Health Professional United States
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 4/18/2007 Physician United States
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 5/17/2007 Physician United States
Primary
Concomitant
Stomatitis Life Threatening 4/2/2007 81 Male 220 lb 6/29/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Nausea Other Serious 3/31/2007 61 Male 132 lb 7/18/2007 Greece
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Other Serious 3/31/2007 Male 132 lb 9/26/2007 Greece
Primary
Concomitant
Renal Failure Life Threatening 8/16/2007 Male 9/27/2007 Australia
Primary
Concomitant
Vasculitis Hospitalization 9/27/2005 Female 214 lb 10/11/2007 Other Health Professional Italy
Primary
Concomitant
Renal Failure Hospitalization 7/9/2007 Male 11/30/2007 Australia
Primary
Concomitant
Renal Failure Hospitalization 7/5/2007 Male 12/20/2007 Australia
Primary
Concomitant
White Blood Cell Count Increased Death 6/7/2006 77 Male 143 lb 12/27/2007 Physician Japan
Primary
Concomitant
Malignant Respiratory Tract Neoplasm Other Serious 12/1/2003 62 Female 1/31/2008 Physician Sweden
Primary
Concomitant
Vasculitis Hospitalization 9/27/2005 Female 214 lb 4/21/2008 Other Health Professional Italy
Primary
Concomitant
Vasculitis Hospitalization 9/27/2005 Female 214 lb 5/1/2008 Other Health Professional Italy
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance 1/1/2008 Male 190 lb 6/12/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/19/2008 Female 190 lb 6/12/2008 United States
Primary
Concomitant
Sensory Disturbance 4/8/2008 Female 6/12/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 5/15/2008 73 Female 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral 4/1/2008 Female 265 lb 9/13/2008 Consumer United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 5/15/2008 73 Female 119 lb 9/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2008 Male 200 lb 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Arrhythmia Death 8/7/2007 10/24/2008 Consumer Argentina
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/4/2008 51 Female 4/8/2008 Pharmacist United States
Primary
Concomitant
Melaena Hospitalization 2/13/2008 61 Female 234 lb 11/11/2008 Pharmacist United States
Primary
Concomitant
Skin Lesion Hospitalization 59 Female 11/19/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 11/25/2008 Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 59 Female 11/26/2008 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/1/2007 Female 12/8/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 59 Female 216 lb 1/12/2009
Primary
Secondary
Concomitant
Palpitations Other Serious 11/23/2007 79 Female 2/16/2009 Consumer United States
Primary
Concomitant
Palpitations Other Serious 11/23/2008 79 Female 2/19/2009 Consumer United States
Primary
Concomitant
Vaginal Infection Other Serious Female 135 lb 3/14/2009 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 10/1/2008 Female 115 lb 3/16/2009 Physician Puerto Rico
Primary
Concomitant
Paraesthesia 9/1/2008 Female 175 lb 6/11/2009 United States
Primary
Concomitant
Palpitations 4/20/2009 Female 258 lb 6/12/2009 United States
Primary
Concomitant
Palpitations Hospitalization 83 Female 170 lb 7/2/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/14/2009 62 Male 8/17/2009 Physician Japan
Primary
Secondary
Concomitant
Blood Glucose Increased 4/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Unevaluable Event Death Male 8/31/2009 United States
Primary
Concomitant
Tuberculosis Hospitalization 3/25/2002 Female 9/11/2009 Belgium
Primary
Concomitant
Incorrect Dose Administered 6/1/2007 Female 190 lb 9/11/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/28/2007 Female 276 lb 9/12/2009 Consumer United States
Primary
Concomitant
Stomatitis Hospitalization 8/20/2009 84 Female 137 lb 9/18/2009 Physician Austria
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2005 Male 9/18/2009 United States
Primary
Concomitant
Drug Dose Omission Female 128 lb 9/19/2009 United States
Primary
Concomitant
Stomatitis Hospitalization 8/20/2009 84 Female 137 lb 9/25/2009 Physician Austria
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/16/2009 60 Female 10/6/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 11/2/2009 Australia
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/23/2009 68 Female 226 lb 10/30/2009 Physician United States
Primary
Concomitant
Sepsis Death Male 11/13/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/14/2009 62 Male 11/20/2009 Physician Japan
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 10/13/2009 Male 147 lb 11/20/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/23/2009 68 Female 226 lb 11/25/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 11/17/2009 Female 162 lb 12/11/2009 Physician Argentina
Primary
Concomitant
Staphylococcal Infection Other Serious 11/17/2009 Female 162 lb 12/15/2009 Argentina
Primary
Concomitant
Infusion Related Reaction Other Serious 10/13/2009 Male 147 lb 12/23/2009 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2004 67 Female 12/29/2009 Other Health Professional Italy
Primary
Concomitant
Staphylococcal Infection Other Serious 11/17/2009 Female 162 lb 12/28/2009 Physician Argentina
Primary
Concomitant
Renal Cell Carcinoma Other Serious 1/18/2008 Male 186 lb 1/14/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 11/17/2009 Female 162 lb 2/1/2010 Argentina
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 2/23/2010 Australia
Primary
Concomitant
Leukopenia Hospitalization 3/3/2010 68 Female 117 lb 3/18/2010 Physician Germany
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2008 Female 209 lb 3/19/2010 Brazil
Primary
Concomitant
Leukopenia Hospitalization 3/3/2010 68 Female 117 lb 3/24/2010 Other Health Professional Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 12/20/2009 71 Female 146 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 2/24/2009 Female 3/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2008 67 Female 209 lb 4/14/2010 Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 7/19/2008 76 Male 199 lb 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Migraine Hospitalization 4/1/2010 35 Female 125 lb 4/22/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/16/2009 60 Female 4/30/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/13/2008 76 Male 199 lb 5/3/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 76 Male 156 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 76 Male 156 lb 5/18/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 59 Female 138 lb 5/28/2010 Consumer United States
Primary
Secondary
Concomitant
Psoriasis Other Serious 1/1/2010 63 Male 6/3/2010 Physician United States
Primary
Concomitant
Psoriasis Other Serious 1/1/2010 63 Male 6/7/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 76 Male 156 lb 6/8/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 76 Male 156 lb 7/1/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 63 Male 7/16/2010 Physician Australia
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 63 Male 8/18/2010 Physician Australia
Primary
Concomitant
Paraesthesia 1/1/2003 67 Male 8/29/2010 Consumer United States
Primary
Concomitant
Toothache Other Serious 1/1/2010 68 Female 200 lb 9/3/2010 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2008 67 Female 209 lb 9/23/2010 Consumer Brazil
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 11/11/2010 Physician Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 9/16/2009 60 Female 155 lb 12/8/2010 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 8/12/2010 60 Female 154 lb 12/10/2010 Consumer Brazil
Primary
Concomitant
Respiratory Arrest Other Serious 9/26/2010 66 Male 188 lb 12/10/2010 Physician Brazil
Primary
Secondary
Concomitant
Psoriasis 11/1/2009 12/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vulvovaginal Candidiasis Other Serious 1/1/2010 48 Female 256 lb 12/17/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/20/2009 12/17/2010 Physician United States
Primary
Secondary
Concomitant
Skin Irritation Hospitalization 4/1/2010 52 Female 150 lb 12/20/2010 Consumer Brazil
Primary
Secondary
Concomitant
Infection 4/1/2010 12/21/2010 Consumer United States
Primary
Concomitant
Gastroenteritis Viral 6/1/2010 12/22/2010 Consumer United States
Primary
Concomitant
Respiratory Arrest Other Serious 9/26/2010 66 Male 188 lb 12/17/2010 Physician Brazil
Primary
Concomitant
Ischaemic Cardiomyopathy Hospitalization 9/20/2010 63 Female 153 lb 12/15/2010 Other Health Professional Argentina
Primary
Concomitant
Ischaemic Cardiomyopathy Hospitalization 7/30/2010 62 Female 153 lb 12/10/2010 Other Health Professional Argentina
Primary
Concomitant
Bronchitis Hospitalization 7/30/2010 62 Female 153 lb 12/29/2010 Other Health Professional Argentina
Primary
Concomitant
Anaemia Other Serious 12/11/2010 60 Female 222 lb 1/19/2011 Consumer United States
Primary
Concomitant
Hypotension Other Serious 1/1/2010 48 Female 154 lb 1/21/2011 Consumer United Kingdom
Primary
Concomitant
Hyperglycaemia Hospitalization 7/30/2010 62 Female 153 lb 1/14/2011 Other Health Professional Argentina
Primary
Concomitant
Uterine Enlargement Female 140 lb 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 57 Female 1/29/2011 Consumer United States
Primary
Concomitant
Visual Impairment 8/20/2010 55 Female 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Discolouration 4/10/2010 59 Female 1/29/2011 Consumer United States
Primary
Concomitant
Cardiac Pacemaker Replacement Other Serious 1/1/2010 73 Male 244 lb 1/29/2011 Physician United States
Primary
Concomitant
Injection Site Pain 11/10/2010 68 Female 1/30/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/27/2010 56 Female 1/30/2011 Consumer United States
Primary
Concomitant
Fungal Infection Female 1/30/2011 Consumer United States
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 2/4/2011 Physician Canada
Primary
Concomitant
Iritis Other Serious 60 Female 2/8/2011 Physician United States
Primary
Concomitant
Erythrodermic Psoriasis Other Serious 77 Female 3/1/2011 Physician Spain
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 1/24/2011 50 Male 144 lb 3/4/2011 Physician South Africa
Primary
Concomitant
Thyroid Neoplasm Hospitalization 4/21/2010 56 Female 170 lb 3/8/2011 Physician Hungary
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 1/24/2011 50 Male 144 lb 3/21/2011 Physician South Africa
Primary
Concomitant
Bladder Cancer Hospitalization 10/29/2010 70 Male 169 lb 4/15/2011 Physician Canada
Primary
Concomitant
Malaise Other Serious 1/1/2010 48 Female 154 lb 5/3/2011 Consumer United Kingdom
Primary
Concomitant
Death Death 12/5/2009 75 Female 131 lb 5/5/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/16/2009 60 Female 155 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/1/2009 60 Female 155 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Brain Injury Death 60 Female 155 lb 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 12/5/2009 75 Female 131 lb 5/27/2011 Physician United States
Primary
Concomitant
Bladder Cancer Hospitalization 10/29/2010 70 Male 169 lb 6/3/2011 Physician Canada
Primary
Concomitant
Psoriasis Other Serious 1/1/2011 63 Female 226 lb 6/14/2011 Physician Germany
Primary
Concomitant
Neuropathy Peripheral Hospitalization Male 6/15/2011 Physician United States
Primary
Concomitant
Urosepsis Hospitalization 4/6/2011 74 Male 132 lb 6/22/2011 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 6/20/2011 60 Male 190 lb 7/5/2011 Physician Australia
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 7/8/2011 Physician Canada
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 4/6/2011 74 Male 132 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Psoriasis Other Serious 1/1/2009 47 Male 215 lb 7/28/2011 Physician United States
Primary
Concomitant
Dysstasia Other Serious 10/1/2006 58 Male 145 lb 8/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 1/1/2009 47 Male 215 lb 8/9/2011 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 12/2/2010 57 Female 183 lb 8/10/2011 Consumer Turkey
Primary
Concomitant
Nausea Other Serious 1/1/2009 60 Female 155 lb 8/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Neoplasm Hospitalization 4/21/2010 56 Female 170 lb 8/17/2011 Physician Hungary
Primary
Secondary
Concomitant
Nodule Other Serious 1/1/2006 70 Female 8/24/2011 Consumer United States
Primary
Concomitant

Drug Data