Methotrexate combined with Rabeprazole Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Right Ventricular Failure Hospitalization 12/25/2003 78 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2005 69 Female 2/10/2006 Consumer Australia
Primary
Concomitant
Depression Other Serious 4/1/2005 Female 185 lb 2/10/2006 United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 2/2/2005 Female 159 lb 2/10/2006 United Kingdom
Primary
Concomitant
Blood Pressure Decreased Death 2/13/2005 64 Male 223 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mammogram Abnormal Other Serious 1/1/2006 46 Female 80 lb 3/28/2006 Other Health Professional United States
Primary
Concomitant
Tonsillitis Other Serious 11/2/2005 Female 119 lb 5/5/2006 Netherlands
Primary
Concomitant
Tonsillitis Other Serious 11/2/2005 Female 119 lb 5/12/2006 Netherlands
Primary
Concomitant
Death Life Threatening 3/12/2006 Male 117 lb 5/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tonsillitis Other Serious 11/2/2005 Female 119 lb 6/2/2006 Netherlands
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/10/2005 Male 165 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Life Threatening Male 117 lb 7/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Hospitalization 5/3/2006 Female 7/11/2006 Australia
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious Female 155 lb 7/14/2006 Consumer Canada
Primary
Concomitant
Death Hospitalization 5/3/2006 Female 8/1/2006 Australia
Primary
Concomitant
Urinary Tract Infection Other Serious 6/2/2005 Female 185 lb 8/23/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 8/19/2005 74 Male 126 lb 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 10/31/2006 Female 11/22/2006 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 10/10/2006 56 Female 12/4/2006 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 10/10/2006 56 Female 12/12/2006 Other Health Professional Canada
Primary
Concomitant
Tonsillitis Hospitalization 11/2/2005 Female 119 lb 12/15/2006 Netherlands
Primary
Concomitant
Hepatitis Hospitalization 7/24/2002 74 Male 167 lb 10/7/2006 Physician United States
Primary
Secondary
Concomitant
Femur Fracture Other Serious 8/17/2004 Female 159 lb 1/9/2007 Consumer United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/10/2006 Female 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 5/19/2005 Male 117 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 8/1/2006 Male 1/22/2007 Physician Portugal
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/10/2005 Male 165 lb 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/10/2005 Male 165 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Death 8/31/2006 Male 168 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 12/18/2005 Male 168 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gait Disturbance Hospitalization 6/28/2005 Male 154 lb 3/7/2007 Consumer United Kingdom
Primary
Concomitant
Stress Other Serious 12/21/2006 80 Female 81 lb 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
Pain Hospitalization 4/2/2007 Female 190 lb 4/25/2007 Consumer Canada
Primary
Concomitant
Pain Hospitalization 4/2/2007 Female 190 lb 5/2/2007 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 6/11/2007 Male 101 lb 7/13/2007 Physician United Kingdom
Primary
Concomitant
Urticaria Life Threatening 44 Female 7/18/2007 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2006 Female 110 lb 7/27/2007 Canada
Primary
Concomitant
Intestinal Obstruction Hospitalization 7/19/2007 Male 148 lb 8/3/2007 Canada
Primary
Concomitant
Viral Infection Hospitalization 11/15/2005 63 Female 8/3/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 12/4/2006 49 Female 8/10/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 12/4/2006 49 Female 8/10/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 12/5/2006 70 Female 9/3/2007 Pharmacist Japan
Primary
Secondary
Small Intestinal Obstruction Hospitalization 7/19/2007 Male 148 lb 9/5/2007 Canada
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 Female 178 lb 9/7/2007 Consumer United States
Primary
Concomitant
Stomatitis Hospitalization 3/1/2007 Female 203 lb 9/14/2007 Consumer United States
Primary
Secondary
Concomitant
Tooth Loss Hospitalization 4/2/2007 Female 190 lb 9/28/2007 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 4/21/2007 Female 9/28/2007 Other Health Professional Japan
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 8/1/2007 Female 119 lb 10/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Loss Hospitalization 4/2/2007 Female 190 lb 10/8/2007 Physician Canada
Primary
Concomitant
Stomatitis Other Serious Female 135 lb 10/22/2007 Canada
Primary
Concomitant
Ocular Hyperaemia Hospitalization 3/1/2007 Female 203 lb 10/23/2007 Consumer United States
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 3/1/2004 Female 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Diplegia Hospitalization 10/1/2007 Female 11/8/2007 Canada
Primary
Concomitant
Coronary Artery Occlusion Other Serious 10/18/2007 Male 148 lb 11/9/2007 Canada
Primary
Concomitant
Diplegia Hospitalization 10/1/2007 Female 11/9/2007 Canada
Primary
Concomitant
Myocardial Ischaemia Hospitalization 5/3/2006 Female 11/16/2007 Australia
Primary
Concomitant
Myelitis Transverse Hospitalization 10/1/2007 Female 11/16/2007 Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 5/3/2006 Female 11/21/2007 Australia
Primary
Concomitant
Movement Disorder Hospitalization 11/12/2007 Female 11/21/2007 Canada
Primary
Concomitant
Gastric Ulcer Other Serious 10/20/2006 Female 181 lb 11/27/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Surgery Hospitalization 4/1/2007 Female 190 lb 12/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Myelitis Transverse Hospitalization 10/1/2007 Female 12/14/2007 Canada
Primary
Concomitant
Drug Ineffective 1/1/2005 Female 101 lb 12/14/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/1/2007 Female 227 lb 12/14/2007 Consumer United States
Primary
Concomitant
Pain 9/1/2007 Female 130 lb 12/14/2007 United States
Primary
Concomitant
Injection Site Haemorrhage 10/23/2007 Female 180 lb 12/14/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 Female 178 lb 1/4/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 6/7/2006 77 Male 143 lb 12/27/2007 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 1/2/2008 65 Female 2/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 12/18/2007 65 Female 117 lb 3/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Streptococcal Sepsis Other Serious 4/1/2007 Female 190 lb 3/7/2008 United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 3/5/2008 Female 3/12/2008 Pharmacist United Kingdom
Primary
Concomitant
Acute Sinusitis 2/1/2008 Female 189 lb 3/15/2008 Consumer United States
Primary
Concomitant
Myelitis Transverse Hospitalization 10/1/2007 Female 182 lb 3/20/2008 Canada
Primary
Concomitant
Paraesthesia Other Serious 9/1/2007 Female 183 lb 4/2/2008 Physician Ireland
Primary
Concomitant
Tremor Other Serious Male 250 lb 4/15/2008 Canada
Primary
Concomitant
Rash Pustular Hospitalization 4/10/2007 Male 146 lb 4/18/2008 United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2004 Female 163 lb 4/24/2008 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness 10/1/2006 Female 113 lb 5/30/2008 Consumer United States
Primary
Concomitant
Spinal Fusion Surgery Other Serious 4/28/2008 Female 145 lb 5/30/2008 Canada
Primary
Concomitant
Pain In Extremity 4/11/2008 Female 211 lb 6/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 10/19/2004 Male 161 lb 6/30/2008 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/20/2007 Male 117 lb 7/1/2008 Physician Japan
Primary
Secondary
Concomitant
Skin Cancer Other Serious 3/24/2006 65 Male 141 lb 7/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sinusitis Hospitalization 1/1/2007 Female 140 lb 7/3/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/3/2008 Female 115 lb 7/11/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/18/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/18/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/25/2008 Japan
Primary
Concomitant
Hepatic Neoplasm Life Threatening 3/1/2008 Male 220 lb 7/31/2008 France
Primary
Concomitant
Rib Fracture Other Serious Female 119 lb 8/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/20/2007 Male 117 lb 8/28/2008 Physician Japan
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 6/12/2008 Female 168 lb 9/3/2008 Other Health Professional United States
Primary
Concomitant
Cellulitis 6/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Injection Site Pain 7/3/2008 Female 135 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Swelling 12/1/2007 Female 150 lb 9/12/2008 Consumer United States
Primary
Concomitant
Rib Fracture Other Serious 8/25/2007 Female 119 lb 9/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/25/2008 Female 130 lb 9/17/2008 Physician Canada
Primary
Concomitant
Hepatic Neoplasm Life Threatening 4/1/2008 Male 220 lb 9/18/2008 France
Primary
Concomitant
Sudden Death Death 9/9/2008 Female 9/19/2008 United States
Primary
Concomitant
Lymphoma Hospitalization 8/27/2007 Female 137 lb 9/19/2008 Physician Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 9/24/2008 Japan
Primary
Concomitant
Joint Dislocation Other Serious 5/8/2008 73 Female 128 lb 10/13/2008 Consumer United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 9/1/2008 65 Female 10/14/2008 Physician France
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 10/17/2008 Japan
Primary
Concomitant
Skin Bacterial Infection Hospitalization 8/24/2007 Female 126 lb 10/28/2008 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 4/1/2003 Female 10/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Microsurgery To Hand Hospitalization 1/19/2006 Female 170 lb 11/3/2008 United Kingdom
Primary
Concomitant
Soft Tissue Disorder Hospitalization 1/19/2006 Female 170 lb 11/4/2008 United Kingdom
Primary
Concomitant
Tuberculosis Hospitalization 7/23/2008 Female 154 lb 11/25/2008 Physician Japan
Primary
Secondary
Concomitant
Accidental Exposure 9/5/2008 Male 185 lb 12/12/2008 Consumer United States
Primary
Concomitant
Rash Generalised 9/15/2008 Female 12/12/2008 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation 3/1/2008 Female 190 lb 12/12/2008 Consumer United States
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 12/19/2008 Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/30/2008 Female 101 lb 12/31/2008 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Death 1/9/2008 Male 223 lb 2/18/2009 United Kingdom
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 2/26/2009 Japan
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 Female 128 lb 3/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 112 lb 3/13/2009 Canada
Primary
Secondary
Concomitant
Urinary Tract Infection 10/25/2008 Female 3/14/2009 United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/2004 75 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization Female 112 lb 4/3/2009 Canada
Primary
Concomitant
Interacting
Bone Pain Other Serious 12/1/2008 Female 4/8/2009 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 4/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 4/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 3/24/2006 65 Male 141 lb 5/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Bone Pain Other Serious 12/1/2008 Female 5/4/2009 Japan
Primary
Concomitant
Bone Pain Other Serious 12/1/2008 Female 5/4/2009 Japan
Primary
Concomitant
Bone Pain Other Serious 12/1/2008 Female 5/21/2009 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 43 5/25/2009 Other Health Professional Canada
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/10/2009 Female 111 lb 6/1/2009 Physician Japan
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 6/2/2009 Japan
Primary
Concomitant
Bone Pain Other Serious 12/12/2008 Female 6/5/2009 Japan
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 2/25/2009 Female 96 lb 6/16/2009 Japan
Primary
Concomitant
Respiratory Failure Hospitalization 3/10/2009 Female 111 lb 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/24/2007 Female 6/19/2009 Physician United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 2/25/2009 Female 96 lb 6/25/2009 Japan
Primary
Concomitant
Bone Pain Other Serious 12/12/2008 Female 7/16/2009 Japan
Primary
Concomitant
Femoral Neck Fracture Life Threatening 8/1/2007 Female 119 lb 7/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 7/21/2009 Japan
Primary
Concomitant
Lymphoma Hospitalization 7/12/2009 Female 128 lb 8/10/2009 Physician Canada
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 8/11/2009 Japan
Primary
Concomitant
Lymphoma Hospitalization 7/12/2009 Female 128 lb 8/14/2009 Physician Canada
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/27/2008 Male 8/18/2009 Japan
Primary
Concomitant
Pyelonephritis Hospitalization 2/25/2009 Female 81 lb 8/21/2009 Japan
Primary
Concomitant
Anaemia Folate Deficiency Other Serious 5/25/2009 Female 109 lb 8/26/2009 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data