Methotrexate combined with Norco

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Injection Site Reaction 7/24/2006 Female 12/18/2006 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 8/19/2006 30 Female 276 lb 11/6/2006 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Male 8/6/2007 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2007 Female 188 lb 8/20/2007 Consumer United States
Primary
Concomitant
Synovitis Other Serious 1/1/2002 Female 120 lb 10/25/2007 Physician United States
Primary
Concomitant
Synovitis Other Serious 1/1/2002 Female 120 lb 11/6/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 11/1/2007 Female 12/7/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 11/1/2007 Female 204 lb 12/27/2007 Physician United States
Primary
Concomitant
Stress 3/1/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 6/1/2008 Female 133 lb 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Synovitis Other Serious 1/1/2002 Female 120 lb 2/12/2009 Consumer United States
Primary
Concomitant
Tendon Rupture Required Intervention 12/1/2007 74 Male 195 lb 3/27/2009 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome 1/1/2008 5/19/2009 Consumer United States
Primary
Concomitant
Tenosynovitis Other Serious 8/1/2007 73 Male 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tenosynovitis Hospitalization 3/27/2009 65 Female 192 lb 5/20/2009 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2009 Male 5/28/2009 Physician United States
Primary
Concomitant
Paraesthesia 7/1/2008 Male 237 lb 6/11/2009 United States
Primary
Concomitant
Rhinorrhoea 1/1/2009 Female 176 lb 6/11/2009 Physician United States
Primary
Concomitant
Spondylolisthesis 1/1/2008 Female 155 lb 6/12/2009
Primary
Concomitant
Tooth Fracture 10/1/2008 Female 160 lb 6/12/2009 Consumer United States
Primary
Concomitant
Urticaria 6/13/2009 Female 270 lb 9/19/2009 United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 1/1/2009 Female 140 lb 10/2/2009 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 6/1/2008 Female 131 lb 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/18/2009 77 Female 12/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Abscess 7/25/2009 Female 158 lb 12/10/2009 Physician United States
Primary
Concomitant
Skin Irritation 7/23/2009 Female 12/10/2009 Physician United States
Primary
Concomitant
Meniscus Lesion Other Serious 1/1/2008 Female 247 lb 12/23/2009 United States
Primary
Concomitant
Meniscus Lesion Other Serious 1/1/2008 Female 247 lb 12/29/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/18/2009 77 Female 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious Female 208 lb 1/19/2010 Physician United Kingdom
Primary
Secondary
Pneumonia Hospitalization 3/12/2008 Female 194 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/18/2009 77 Female 2/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 10/23/2009 Female 208 lb 2/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2009 Female 481 lb 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/12/2008 Female 194 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Fatigue 8/27/2008 53 Female 220 lb 2/22/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Exfoliation 51 Female 170 lb 2/22/2010 Consumer United States
Primary
Concomitant
Oral Disorder 9/1/2009 59 Female 115 lb 2/22/2010 Consumer United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 9/11/2009 56 Female 2/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/18/2009 77 Female 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2009 69 Female 481 lb 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2010 83 Male 156 lb 4/23/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2009 69 Female 481 lb 4/28/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/12/2008 67 Female 194 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 10/23/2009 30 Female 208 lb 2/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2010 83 Male 156 lb 6/15/2010 Physician United States
Primary
Concomitant
Haemorrhoids Other Serious 9/28/2009 60 Female 142 lb 6/9/2010 United States
Primary
Concomitant
Vomiting 11/1/2007 44 Female 115 lb 7/17/2010 Consumer United States
Primary
Concomitant
Surgery Other Serious Female 7/15/2010 Consumer United States
Primary
Concomitant
Unevaluable Investigation Other Serious Female 117 lb 7/30/2010 Consumer United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious Female 8/16/2010 Physician United States
Primary
Concomitant
Pneumonia Streptococcal Hospitalization 3/1/2010 63 Female 152 lb 8/18/2010 Physician United States
Primary
Concomitant
Swollen Tongue Other Serious 9/5/2010 52 Female 120 lb 9/5/2010 United States
Primary
Secondary
Concomitant
Gastroenteritis Viral Hospitalization 9/1/2010 55 Female 186 lb 9/20/2010 Physician United States
Primary
Concomitant
Nausea Other Serious 1/1/2009 55 Male 9/20/2010 Consumer United States
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Hospitalization 9/1/2010 55 Female 186 lb 9/23/2010 Physician United States
Primary
Concomitant
Tongue Biting 71 Male 10/13/2010 Consumer United States
Primary
Concomitant
Respiratory Syncytial Virus Test Positive Life Threatening 11/16/2010 14 Female 130 lb 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 9/11/2009 11/30/2010 Physician United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Life Threatening 11/16/2010 14 Female 130 lb 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 6/1/2007 45 Male 12/7/2010 Lawyer United States
Primary
Concomitant
Pneumonitis Life Threatening 11/16/2010 14 Female 130 lb 12/17/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/1/2005 60 Female 245 lb 12/23/2010 United States
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 11/16/2010 14 Female 130 lb 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Life Threatening 11/16/2010 14 Female 130 lb 1/5/2011 Physician United States
Primary
Secondary
Concomitant
Hydronephrosis Other Serious 5/30/1996 48 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Spleen Disorder Other Serious 11/1/2005 60 Female 245 lb 1/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Latent Tuberculosis Other Serious 2/1/2010 53 Male 200 lb 1/28/2011 United States
Primary
Concomitant
Drug Effect Decreased 5/1/2009 49 Female 140 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 6/7/2010 42 Female 1/29/2011 Consumer United States
Primary
Concomitant
Ankle Operation Hospitalization 9/1/2009 61 Female 1/30/2011 Consumer United States
Primary
Concomitant
Myalgia Hospitalization 11/1/2005 60 Female 245 lb 2/1/2011 United States
Primary
Secondary
Concomitant
Renal Atrophy Other Serious 5/30/1996 48 Female 2/10/2011 United States
Primary
Secondary
Concomitant
Gastroenteritis Viral Hospitalization 9/2/2010 55 Female 186 lb 2/14/2011 Physician United States
Primary
Concomitant
Anxiety Other Serious 5/30/1996 48 Female 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 11/1/2005 60 Female 245 lb 3/24/2011 United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/16/2010 14 Female 130 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 9/28/2009 60 Female 142 lb 3/18/2011 Other Health Professional United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 11/1/2005 60 Female 245 lb 5/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/2/2005 49 Female 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 4/21/2011 56 Male 5/26/2011 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 11/1/2005 60 Female 245 lb 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Alopecia 47 Male 179 lb 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Other Serious 5/2/2005 49 Female 6/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 4/21/2011 56 Male 226 lb 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2011 Female 117 lb 6/23/2011 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2005 48 Female 170 lb 7/29/2011 Consumer United States
Primary
Concomitant
Night Sweats Other Serious 11/1/2005 60 Female 245 lb 8/4/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 6/1/2011 85 Female 8/2/2011 Consumer United States
Primary
Concomitant
Cardiomegaly Hospitalization 11/1/2005 60 Female 245 lb 8/16/2011 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/1/2009 61 Female 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 9/1/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/1/2011 85 Female 9/7/2011 Consumer United States
Primary
Concomitant
Injection Site Vesicles Other Serious 1/1/2011 59 Female 9/13/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2005 48 Female 170 lb 9/23/2011 Consumer United States
Primary
Concomitant
Metastases To Peritoneum Other Serious 11/1/2009 61 Female 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 6/1/2011 85 Female 132 lb 9/30/2011 Consumer United States
Primary
Concomitant
Injection Site Vesicles Other Serious 1/1/2011 59 Female 172 lb 10/6/2011 Physician United States
Primary
Concomitant
Headache 6/22/2011 38 Female 207 lb 11/2/2011 Other Health Professional United States
Primary
Concomitant
Fibula Fracture Other Serious Female 11/8/2011 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2011 58 Female 248 lb 11/17/2011 Consumer United States
Primary
Concomitant
Cough Hospitalization 1/1/2011 52 Female 190 lb 11/18/2011 Physician United States
Primary
Concomitant
Chest Pain Other Serious 11/22/2011 45 Female 12/8/2011 Physician United States
Primary
Concomitant
Headache 9/1/2009 35 Female 12/13/2011 Consumer United States
Primary
Concomitant
Angiopathy Other Serious 1/1/2010 70 Male 200 lb 12/16/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization Female 251 lb 12/21/2011 Physician United States
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 11/1/2009 61 Female 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 11/1/2011 74 Female 12/21/2011 Consumer United States
Primary
Concomitant
Haemoptysis Hospitalization Female 251 lb 12/22/2011 Physician United States
Primary
Concomitant
Stress Fracture Other Serious 11/4/2004 46 Female 246 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 12/21/2011 53 Female 143 lb 1/9/2012 Physician United States
Primary
Concomitant
Hiatus Hernia Hospitalization 11/1/2011 74 Female 1/17/2012 Consumer United States
Primary
Concomitant
Abasia Other Serious 1/1/2011 58 Female 248 lb 1/20/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral 5/12/2011 40 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain Other Serious 4/1/2009 28 Female 1/27/2012 Consumer United States
Primary
Concomitant
Nasopharyngitis 1/1/2011 62 Female 1/27/2012 Consumer United States
Primary
Concomitant
Diarrhoea 3/8/2011 55 Female 1/27/2012 Consumer United States
Primary
Concomitant
Arthralgia 12/15/2010 60 Male 1/27/2012 Consumer United States
Primary
Concomitant
Nausea 1/1/2011 51 Female 124 lb 1/27/2012 Consumer United States
Primary
Secondary
Concomitant
Joint Swelling 2/1/2011 58 Female 1/27/2012 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/2/2011 61 Female 1/28/2012 Physician
Primary
Concomitant
Blood Blister 6/8/2011 55 Female 1/28/2012 Consumer United States
Primary
Concomitant
Gait Disturbance 4/1/2011 52 Male 200 lb 1/28/2012 Consumer United States
Primary
Secondary
Concomitant
Nausea 5/13/2011 40 Female 1/28/2012 Consumer United States
Primary
Concomitant
Rash Papular 5/1/2011 63 Female 183 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Haematoma 67 Female 1/28/2012 Consumer United States
Primary
Concomitant
Sinus Congestion 11/28/2011 54 Male 1/29/2012 Consumer United States
Primary
Concomitant
Joint Swelling 5/1/2011 40 Female 1/28/2012 Consumer United States
Primary
Concomitant
Fatigue 10/5/2011 34 Male 1/28/2012 Consumer United States
Primary
Concomitant
Abdominal Pain 8/31/2011 50 Female 1/28/2012 Consumer United States
Primary
Concomitant
Off Label Use Female 120 lb 1/29/2012 Consumer United States
Primary
Concomitant
Weight Decreased 2/1/2011 63 Female 155 lb 1/28/2012 Consumer United States
Primary
Concomitant
Nodule Other Serious 1/1/2010 70 Male 200 lb 2/1/2012 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 11/1/2011 74 Female 2/3/2012 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 11/22/2011 45 Female 2/9/2012 Physician United States
Primary
Concomitant
Cardiomegaly Hospitalization 5/2/2005 49 Female 2/13/2012 Lawyer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/1/2011 74 Female 2/24/2012 Consumer United States
Primary
Concomitant
Constipation Other Serious 6/1/2011 85 Female 132 lb 2/24/2012 Physician United States
Primary
Concomitant
Cardiac Enzymes Increased Other Serious 9/1/2011 38 Female 134 lb 3/1/2012 Physician United States
Primary
Secondary
Concomitant
Hepatic Lesion Hospitalization 5/2/2005 49 Female 3/14/2012 Consumer United States
Primary
Secondary
Concomitant
Constipation Hospitalization 9/1/2011 74 Female 3/13/2012 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/2/2005 49 Female 3/28/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Central Nervous System Life Threatening 1/1/2012 71 Female 141 lb 4/4/2012 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/18/2011 70 Male 274 lb 4/5/2012 Physician United States
Primary
Concomitant
Pain Other Serious 2/1/2011 58 Female 174 lb 4/9/2012 Consumer United States
Primary
Concomitant
Drug Effect Decreased Other Serious Male 223 lb 4/16/2012 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/18/2011 70 Male 274 lb 4/25/2012 Physician United States
Primary
Concomitant

Drug Data