Methotrexate combined with Naprosyn

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Peritoneal Tuberculosis Other Serious 9/1/2005 Male 147 lb 1/16/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 11/1/2000 50 Male 196 lb 1/23/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 11/1/2000 50 Male 196 lb 2/14/2006 Physician United States
Primary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 7/1/2004 Female 2/24/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2000 50 Male 196 lb 3/3/2006 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 1/9/2006 67 Female 3/22/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2000 50 Male 196 lb 3/24/2006 Physician United States
Primary
Concomitant
Red Blood Cell Count Increased Other Serious 3/16/2006 Male 155 lb 3/31/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2000 50 Male 196 lb 4/7/2006 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 1/9/2006 67 Female 4/25/2006 Other Health Professional United States
Primary
Concomitant
Polycythaemia Other Serious 1/1/2006 Male 155 lb 6/20/2006 Other Health Professional United States
Primary
Concomitant
Mass Required Intervention 1/18/2006 61 Female 200 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Polycythaemia Other Serious 1/1/2006 Male 155 lb 6/30/2006 Other Health Professional United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Male 7/10/2006 Physician United States
Primary
Concomitant
Breast Cancer Life Threatening 4/14/2006 Female 242 lb 9/18/2006 Physician United States
Primary
Concomitant
Hodgkin's Disease Other Serious 9/1/2006 75 Male 9/27/2006 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 1/9/2006 67 Female 10/12/2006 Other Health Professional United States
Primary
Concomitant
Hodgkin's Disease Other Serious 9/7/2006 Male 175 lb 11/6/2006 Physician United States
Primary
Concomitant
Crohn's Disease Other Serious 8/16/2006 Female 58 lb 11/8/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/6/2006 Female 131 lb 11/10/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 8/25/2006 15 Female 11/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 4/6/2006 Female 131 lb 11/29/2006 Physician United States
Primary
Concomitant
Uveitis Other Serious 8/16/2006 Female 58 lb 12/5/2006 Physician United States
Primary
Concomitant
Hodgkin's Disease Other Serious 9/7/2006 Male 190 lb 12/6/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Lymphocytic Lymphoma Other Serious 5/17/2005 Male 164 lb 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Pruritus Generalised 3/22/2006 Female 12/14/2006 Consumer United States
Primary
Concomitant
Retroperitoneal Fibrosis Other Serious 5/1/2006 Male 12/21/2006 Physician Canada
Primary
Concomitant
Retroperitoneal Fibrosis Other Serious 5/1/2006 Male 1/25/2007 Physician Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 12/7/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 6/17/2006 Female 161 lb 4/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Hospitalization 8/25/2006 15 Female 4/3/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 53 Female 4/5/2007 Lawyer United States
Primary
Secondary
Concomitant
Crohn's Disease Other Serious 8/16/2006 Female 58 lb 4/5/2007 Physician United States
Primary
Concomitant
Wheezing Other Serious 12/15/2005 Male 228 lb 4/6/2007 Other Health Professional Canada
Primary
Concomitant
Pigmentation Disorder Other Serious 7/6/2006 Female 50 lb 4/6/2007 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 8/25/2006 15 Female 4/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 1/1/2000 Male 112 lb 5/7/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/16/2007 66 Female 5/11/2007 Physician Spain
Primary
Secondary
Concomitant
Crohn's Disease Other Serious 1/21/2004 Female 58 lb 5/15/2007 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2007 14 Female 5/22/2007 Physician Norway
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 7/8/2006 Female 50 lb 5/22/2007 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 3/7/2007 65 Male 5/25/2007 Physician Sweden
Primary
Concomitant
Pneumonia Other Serious 2/16/2007 66 Female 6/25/2007 Physician Spain
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 5/9/2007 58 Female 9/7/2007 Other Health Professional France
Primary
Concomitant
Injection Site Swelling Other Serious 6/19/2007 Female 189 lb 9/13/2007 Other Health Professional Ireland
Primary
Concomitant
Metastatic Malignant Melanoma Death 3/22/2007 Male 9/13/2007 Physician United States
Primary
Concomitant
Metastatic Malignant Melanoma Death 1/8/2007 Male 9/25/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/14/2007 Consumer United States
Primary
Concomitant
Vulval Cancer Other Serious 1/1/2003 Female 185 lb 12/6/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/28/2006 Female 11/9/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Congestion 2/24/2007 Male 161 lb 12/11/2007 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 12/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vitamin D Decreased Disability 2/20/2007 Female 12/20/2007 Physician Canada
Primary
Concomitant
Myocardial Infarction Life Threatening 12/12/2007 Male 1/28/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 1/22/2008 Male 176 lb 2/15/2008 Physician Turkey
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Other Serious 2/9/2007 Female 185 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Psychotic Disorder Life Threatening 2/11/2008 5 Male 90 lb 3/25/2008 Physician
Primary
Concomitant
Subcutaneous Abscess Hospitalization 1/1/2008 Female 210 lb 3/25/2008 Consumer Canada
Primary
Concomitant
Psychotic Disorder Life Threatening 2/11/2008 Male 90 lb 4/2/2008 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 1/22/2008 Male 176 lb 4/14/2008 Physician Turkey
Primary
Concomitant
Psychotic Disorder Life Threatening 2/11/2008 Male 90 lb 4/17/2008 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/22/2006 Female 223 lb 4/25/2008 Physician United States
Primary
Concomitant
Subcutaneous Abscess Hospitalization 1/1/2008 Female 210 lb 5/1/2008 Consumer Canada
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 7/12/2007 Female 214 lb 5/8/2008 Consumer United Kingdom
Primary
Concomitant
Wound Hospitalization 1/1/2008 Male 183 lb 5/22/2008 Physician Canada
Primary
Secondary
Concomitant
Wound Hospitalization 1/1/2008 Male 183 lb 6/2/2008 Physician Canada
Primary
Secondary
Concomitant
Abdominal Mass Other Serious 1/25/2007 12 Female 47 lb 6/9/2008 Physician United States
Primary
Secondary
Concomitant
Accidental Exposure 5/6/2008 Female 170 lb 6/13/2008 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Other Serious 3/19/2005 79 Female 98 lb 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 7/9/2008 47 Female 146 lb 7/16/2008 Consumer United States
Primary
Concomitant
Myalgia Other Serious 6/1/2008 65 Female 140 lb 7/17/2008 Consumer United States
Primary
Concomitant
Death Other Serious 54 Female 146 lb 7/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Papular 5/28/2008 Female 195 lb 9/12/2008 Physician United States
Primary
Concomitant
Skin Wrinkling 4/23/2008 Female 135 lb 9/12/2008 United States
Primary
Concomitant
Pain 5/18/2008 Female 280 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Pain 7/3/2008 Female 9/12/2008 United States
Primary
Concomitant
Herpes Zoster 7/24/2008 Male 180 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Irritation 7/14/2008 Female 101 lb 9/12/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/25/2008 Female 130 lb 9/17/2008 Physician Canada
Primary
Concomitant
Diarrhoea 60 Male 9/23/2008 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 7/12/2008 Female 156 lb 10/1/2008 Canada
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/23/2008 Female 185 lb 10/13/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Other Serious 5/7/2008 54 Female 146 lb 10/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Other Serious 8/26/2008 18 Female 201 lb 10/24/2008 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 7/12/2008 Female 156 lb 11/7/2008 Canada
Primary
Concomitant
Vaginal Haemorrhage Other Serious Female 157 lb 11/12/2008 Canada
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 11/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious Female 157 lb 11/26/2008 Canada
Primary
Concomitant
Musculoskeletal Stiffness 1/2/2008 Female 12/1/2008 Consumer United States
Primary
Concomitant
Pain In Extremity 3/9/2008 Female 12/8/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Asthenia 11/24/2008 Female 139 lb 12/10/2008 Physician United States
Primary
Concomitant
Uterine Cancer Other Serious 10/5/2008 Female 276 lb 12/12/2008 Consumer United States
Primary
Concomitant
Fatigue 8/1/2007 Male 12/12/2008 Consumer United States
Primary
Secondary
Concomitant
Pain Female 209 lb 12/17/2008 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 10/9/2008 Male 12/19/2008 Other Health Professional Italy
Primary
Concomitant
Psoriasis 10/1/2008 67 Female 12/31/2008 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 8/26/2008 18 Female 201 lb 1/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 10/9/2008 Male 1/22/2009 Other Health Professional Italy
Primary
Concomitant
Myocardial Infarction Hospitalization 10/13/2008 Female 100 lb 2/25/2009 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 2/26/2009 United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 10/29/2002 Female 3/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 10/13/2008 Female 100 lb 3/5/2009 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 3/10/2009 United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 2/7/2006 Male 209 lb 3/13/2009 Netherlands
Primary
Concomitant
Injection Site Pain 1/1/2008 Female 56 lb 3/14/2009 United States
Primary
Concomitant
Sinusitis 11/24/2008 Female 140 lb 3/14/2009 United States
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/23/2008 Female 185 lb 3/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain Other Serious 10/19/2008 Female 160 lb 3/27/2009 Physician Canada
Primary
Concomitant
Skin Cancer Other Serious 9/24/2003 Female 157 lb 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/6/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain Other Serious 10/19/2008 Female 160 lb 4/7/2009 Physician Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Secretion Discharge Other Serious 3/25/2009 Male 310 lb 4/16/2009 Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2009 Female 142 lb 4/20/2009 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 2/17/2009 Female 140 lb 4/27/2009 Physician France
Primary
Secondary
Concomitant
Interacting
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Stress Fracture Other Serious 11/7/2008 Female 4/29/2009 Other Health Professional United States
Primary
Concomitant
Secretion Discharge Other Serious 3/25/2009 Male 310 lb 5/5/2009 Canada
Primary
Concomitant
Swelling Face Other Serious 8/26/2008 18 Female 201 lb 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Other Serious 2/16/2007 Female 185 lb 6/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cholecystitis Infective Hospitalization 5/5/2009 43 Male 6/11/2009 Consumer Australia
Primary
Secondary
Accidental Exposure 9/7/2008 Female 140 lb 6/11/2009 United States
Primary
Concomitant
Injection Site Irritation 10/1/2008 Male 6/11/2009 Other Health Professional United States
Primary
Concomitant
Eye Infection Staphylococcal 3/7/2009 Female 188 lb 6/11/2009 Consumer United States
Primary
Concomitant
Pyrexia Female 52 lb 6/11/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 4/4/2009 Female 130 lb 6/12/2009 United States
Primary
Concomitant
Paraesthesia 4/29/2009 Male 140 lb 6/12/2009 United States
Primary
Concomitant
Drug Dose Omission 5/8/2009 Male 216 lb 6/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 6/1/2008 Female 109 lb 6/12/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/28/2009 Female 145 lb 6/12/2009 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2009 Female 142 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Breast Cancer Other Serious 9/15/2004 Female 6/15/2009 United States
Primary
Concomitant
Psoriasis Other Serious 10/13/2007 44 Male 6/17/2009 Physician Canada
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 10/9/2008 Male 6/18/2009 Other Health Professional Italy
Primary
Concomitant
Vaginal Haemorrhage Other Serious Female 157 lb 7/16/2009 Canada
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/31/2009 17 Female 166 lb 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/16/2007 Female 185 lb 8/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 7/4/2009 52 Female 176 lb 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Chillblains Other Serious 1/1/2009 11 Female 68 lb 8/13/2009 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Other Serious Female 8/24/2009 Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 2/16/2007 Female 185 lb 8/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Subcutaneous Abscess Hospitalization 8/1/2009 Female 9/9/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data