Methotrexate combined with Nasonex

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Required Intervention 61 Male 170 lb 2/27/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2002 52 Female 121 lb 4/24/2006 Physician United States
Primary
Concomitant
Histoplasmosis Hospitalization 4/21/2005 Male 4/24/2006 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 6/3/2002 70 Male 130 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 8/20/2001 63 Female 198 lb 4/26/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 60 Female 154 lb 4/27/2006 Physician United States
Primary
Concomitant
Peritonitis Other Serious 12/1/1998 Female 113 lb 5/19/2006 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2006 Female 5/31/2006 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 5/19/2006 Female 6/21/2006 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Hospitalization 4/16/2006 53 Female 8/14/2006 Other Health Professional Sweden
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 6/30/2006 59 Male 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/8/2006 Other Health Professional United States
Primary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/14/2006 Other Health Professional United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/22/2006 51 Male 9/26/2006 Physician Belgium
Primary
Concomitant
Facial Palsy Disability 1/1/2006 60 Female 12/8/2006 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 2/9/2005 69 Female 130 lb 11/28/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Reaction Other Serious 7/1/2005 65 Female 163 lb 11/30/2005 Consumer United States
Primary
Concomitant
Wegener's Granulomatosis Other Serious 1/1/2005 39 Female 115 lb 3/22/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 3/6/2007 79 Female 146 lb 5/11/2007 Pharmacist United States
Primary
Concomitant
Dizziness 8/30/2007 64 Female 115 lb 9/26/2007 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/1/2005 Female 152 lb 11/27/2007 Physician United States
Primary
Concomitant
Injection Site Pain 1/1/2004 Female 152 lb 12/10/2007 Physician United States
Primary
Concomitant
Headache 9/29/2006 Female 12/10/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 2/9/2005 69 Female 130 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/1/2005 Female 152 lb 2/28/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2007 Female 55 lb 6/9/2008 Physician United States
Primary
Concomitant
Photosensitivity Reaction Other Serious 12/27/2007 Male 286 lb 11/25/2008 Physician United States
Primary
Concomitant
Asthenia 11/24/2008 Female 139 lb 12/10/2008 Physician United States
Primary
Concomitant
Pain Female 209 lb 12/17/2008 Physician United States
Primary
Concomitant
Nausea Other Serious Female 107 lb 3/11/2009 Canada
Primary
Secondary
Concomitant
Eye Disorder 75 Female 3/18/2009 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 10/29/2008 Male 265 lb 4/24/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 9/23/2008 Female 4/24/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 2/2/2009 Male 212 lb 6/11/2009 United States
Primary
Concomitant
Drug Ineffective 8/1/2008 Male 175 lb 6/12/2009 Physician United States
Primary
Concomitant
Insomnia 75 Female 6/19/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Weight Increased 1/1/2007 Female 190 lb 9/19/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Impaired Gastric Emptying Other Serious 2/24/2009 Female 10/20/2009 Physician United States
Primary
Concomitant
Endometrial Cancer Metastatic Other Serious Female 261 lb 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 8 Female 66 lb 11/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Osteoarthritis Hospitalization 12/3/2009 Female 200 lb 12/30/2009 Pharmacist Canada
Primary
Concomitant
Sinus Headache Disability 1/1/2009 Female 1/29/2010 Other Health Professional Norway
Primary
Concomitant
B-cell Lymphoma Other Serious 9/1/2009 Female 170 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Neoplasm Other Serious 11/9/2009 65 Female 158 lb 4/16/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/12/2010 52 Male 4/20/2010 Consumer France
Primary
Secondary
Thrombocytopenia Hospitalization 3/29/2010 52 Male 4/12/2010 Physician France
Primary
Secondary
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Tongue Disorder Other Serious 57 Female 6/1/2010 Consumer United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 4/23/2010 68 Female 6/21/2010 Other Health Professional Norway
Primary
Secondary
Concomitant
Urine Odour Abnormal 1/1/2008 53 Female 6/23/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 6/1/2010 50 Female 145 lb 7/9/2010 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 2/1/2009 59 Male 185 lb 7/16/2010 Physician United States
Primary
Concomitant
Tooth Fracture Other Serious 12/1/2007 72 Male 172 lb 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Nausea 7/2/2008 59 Female 165 lb 7/22/2010 Consumer United States
Primary
Concomitant
Dyspepsia Hospitalization 6/17/2010 42 Male 181 lb 8/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Other Serious Male 140 lb 8/13/2010 Consumer Canada
Primary
Concomitant
Coronary Artery Occlusion Other Serious Male 140 lb 8/20/2010 Physician Canada
Primary
Concomitant
Pneumonia Hospitalization 6/1/2010 50 Female 145 lb 10/12/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 10/15/2010 United States
Primary
Secondary
Concomitant
Hypothyroidism Hospitalization 12/22/2009 56 Female 150 lb 10/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 11/11/2010 Physician Canada
Primary
Concomitant
Pneumonia Hospitalization 1/2/2010 51 Female 147 lb 12/28/2010 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 12/9/2010 66 Female 160 lb 1/6/2011 Physician Canada
Primary
Secondary
Concomitant
Spleen Disorder Other Serious 11/1/2005 60 Female 245 lb 1/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Wound Secretion 8/1/2010 56 Female 190 lb 1/29/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission 7/6/2010 38 Male 1/29/2011 Consumer United States
Primary
Concomitant
Diverticulum 7/18/2009 54 Female 1/30/2011 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Pain 9/7/2010 53 Female 1/30/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 9/29/2010 57 Male 1/30/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio 9/4/2010 50 Female 1/30/2011 Consumer United States
Primary
Concomitant
Drug Ineffective 10/1/2010 76 Female 1/30/2011 Consumer United States
Primary
Concomitant
Myalgia Hospitalization 11/1/2005 60 Female 245 lb 2/1/2011 United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 2/4/2011 Physician Canada
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 33 Female 2/22/2011 Other Health Professional Canada
Primary
Concomitant
Atrial Fibrillation 1/1/2008 74 Female 3/11/2011 Consumer United States
Primary
Concomitant
Mesangioproliferative Glomerulonephritis Hospitalization 1/1/2009 48 Female 254 lb 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Endometrial Hypertrophy Other Serious 1/1/2010 66 Female 150 lb 3/18/2011 Consumer Canada
Primary
Concomitant
Tendon Disorder Other Serious 11/1/2005 60 Female 245 lb 3/24/2011 United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 1/1/2010 66 Female 150 lb 4/1/2011 Physician Canada
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 8/23/2010 63 Female 317 lb 4/11/2011 Consumer United Kingdom
Primary
Concomitant
Bladder Cancer Hospitalization 10/29/2010 70 Male 169 lb 4/15/2011 Physician Canada
Primary
Concomitant
Hypertonic Bladder Other Serious 1/1/2010 66 Female 150 lb 4/15/2011 Consumer Canada
Primary
Concomitant
Abdominal Pain Other Serious 1/1/2010 66 Female 150 lb 4/15/2011 Other Health Professional Canada
Primary
Concomitant
Dyspnoea Other Serious 5/31/2010 70 Male 140 lb 4/22/2011 Physician Canada
Primary
Concomitant
Back Pain Hospitalization 8/23/2010 63 Female 144 lb 4/28/2011 Physician United Kingdom
Primary
Concomitant
Myalgia Hospitalization 11/1/2005 60 Female 245 lb 5/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Sinusitis 10/1/2010 67 Female 5/25/2011 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 11/1/2005 60 Female 245 lb 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bladder Cancer Hospitalization 10/29/2010 70 Male 169 lb 6/3/2011 Physician Canada
Primary
Concomitant
Sinusitis Other Serious 50 Female 122 lb 5/26/2011 Pharmacist United States
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 7/8/2011 Physician Canada
Primary
Concomitant
Eye Infection Other Serious 50 Female 122 lb 7/6/2011 Physician United States
Primary
Secondary
Concomitant
Muscle Rupture Other Serious 4/3/2011 50 Male 7/25/2011 Physician Sweden
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/1/2010 72 Male 7/27/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Muscle Rupture Other Serious 4/3/2011 50 Male 7/28/2011 Physician Sweden
Primary
Secondary
Concomitant
Night Sweats Other Serious 11/1/2005 60 Female 245 lb 8/4/2011 Physician United States
Primary
Secondary
Concomitant
Cardiomegaly Hospitalization 11/1/2005 60 Female 245 lb 8/16/2011 United States
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Hospitalization 9/1/2010 25 Female 250 lb 8/31/2011 Consumer United States
Primary
Concomitant
Rash Hospitalization 5/13/2011 58 Female 255 lb 9/23/2011 Consumer United States
Primary
Concomitant
Splenomegaly Hospitalization 6/25/2005 55 Female 10/13/2011 United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 9/1/2011 65 Female 10/13/2011 Consumer United States
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/13/2011 58 Female 255 lb 10/18/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission Other Serious 12/1/2010 73 Female 10/13/2011 Consumer United States
Primary
Concomitant
Injection Site Haematoma 12/1/2010 50 Female 179 lb 10/27/2011 Consumer United States
Primary
Concomitant
Bronchitis 4/28/2011 64 Female 205 lb 10/30/2011 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 1/1/2011 47 Female 174 lb 11/10/2011 Physician Canada
Primary
Concomitant
Skin Disorder 1/1/2011 62 Male 222 lb 11/17/2011 Physician United States
Primary
Concomitant
Fatigue Other Serious 12/1/2011 33 Female 1/17/2012 Consumer Canada
Primary
Concomitant
Hypertension Other Serious 10/1/2011 55 Female 260 lb 1/24/2012 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Death 10/10/2011 63 Female 1/26/2012 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity 2/10/2011 67 Female 210 lb 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 2/11/2011 39 Female 1/27/2012 Consumer United States
Primary
Concomitant
Burning Sensation 1/1/2006 49 Female 110 lb 1/27/2012 Consumer United States
Primary
Concomitant
Cough Other Serious 2/1/2009 43 Female 1/27/2012 Other Health Professional United States
Primary
Concomitant
Dyspnoea 3/17/2011 67 Female 1/27/2012 Consumer United States
Primary
Concomitant
Sinusitis 3/21/2011 57 Female 1/27/2012 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2011 75 Female 150 lb 1/28/2012 Physician United States
Primary
Concomitant
Cough 3/26/2011 60 Female 180 lb 1/28/2012 Consumer United States
Primary
Concomitant
Headache Other Serious 12/1/2010 45 Male 185 lb 1/28/2012 Physician United States
Primary
Concomitant
Throat Tightness 11/1/2011 74 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Swelling 8/25/2011 49 Female 1/28/2012 Consumer United States
Primary
Concomitant
Arthropod Sting 9/3/2011 61 Female 1/28/2012 Consumer United States
Primary
Concomitant
Sinus Disorder 1/1/2011 75 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Haematoma Female 1/29/2012 Consumer United States
Primary
Concomitant
Fatigue Other Serious 55 Female 208 lb 2/7/2012 Pharmacist United States
Primary
Concomitant
Femur Fracture Other Serious 12/8/2009 57 Female 150 lb 3/2/2012 Consumer United States
Primary
Concomitant
Tenderness Other Serious 55 Female 197 lb 3/1/2012 Pharmacist United States
Primary
Concomitant
Death Death Female 3/27/2012 Consumer United States
Primary
Concomitant
Pain Disability 4/7/2011 65 Female 4/3/2012 Physician Canada
Primary
Concomitant
Vaginal Ulceration Hospitalization 62 Female 187 lb 3/26/2012 Lawyer United States
Primary
Concomitant
Fatigue Other Serious 12/1/2011 33 Female 4/9/2012 Other Health Professional Canada
Primary
Concomitant
Histoplasmosis Hospitalization 3/5/2012 87 Male 113 lb 4/13/2012 Physician United States
Primary
Concomitant
Pyrexia Other Serious 12/1/2011 33 Female 4/17/2012 Consumer Canada
Primary
Concomitant
Fracture Displacement Other Serious 12/8/2009 57 Female 150 lb 5/10/2012 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/8/2009 57 Female 150 lb 5/18/2012 Other Health Professional United States
Primary
Concomitant
Sinusitis Hospitalization 12/1/2011 64 Female 166 lb 6/5/2012 Physician United States
Primary
Concomitant
Malaise Other Serious 55 Female 197 lb 5/16/2012 Pharmacist United States
Primary
Concomitant
Cystitis Other Serious 1/1/2011 47 Female 174 lb 6/13/2012 Other Health Professional Canada
Primary
Concomitant
Pain Other Serious 1/1/2009 45 Female 216 lb 6/14/2012 Consumer United States
Primary
Concomitant
Breath Sounds Abnormal Disability Female 226 lb 6/8/2012 Lawyer United States
Primary
Concomitant
Infection Other Serious 1/1/2009 56 Female 147 lb 7/5/2012 Consumer United States
Primary
Secondary
Concomitant
Urticaria 6/1/2012 58 Female 147 lb 7/9/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Sinusitis Hospitalization 12/1/2011 64 Female 166 lb 7/9/2012 Other Health Professional United States
Primary
Concomitant
Bone Pain 1/1/2011 47 Female 174 lb 7/31/2012 Other Health Professional Canada
Primary
Concomitant
Throat Cancer Other Serious 11/1/2005 60 Female 245 lb 8/1/2012 Physician United States
Primary
Secondary
Concomitant

Drug Data