Methotrexate combined with Predonine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 6/18/2004 Female 1/5/2006 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/12/2005 Female 112 lb 1/6/2006 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 6/30/2005 Female 99 lb 1/6/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/18/2004 Female 104 lb 1/12/2006 Physician Japan
Primary
Concomitant
Osteonecrosis Hospitalization 9/1/2004 Male 176 lb 2/6/2006 Physician Japan
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 8/23/2005 Female 2/6/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 10/7/2004 Female 112 lb 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/1/2004 Male 176 lb 3/9/2006 Physician Japan
Primary
Concomitant
Spondylolisthesis Hospitalization 10/29/2005 Female 3/14/2006 Physician Japan
Primary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 3/15/2006 Physician Japan
Primary
Concomitant
Oedema Other Serious 2/21/2005 Male 137 lb 3/21/2006 Physician Japan
Primary
Secondary
Concomitant
Tracheal Injury Life Threatening 1/29/2004 70 Male 144 lb 3/27/2006 Physician Japan
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 3/1/2005 42 Female 3/28/2006 Consumer United States
Primary
Concomitant
Vomiting Disability 11/4/2005 9 Male 53 lb 3/29/2006 Physician Japan
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 6/22/2005 Female 4/3/2006 Physician Japan
Primary
Concomitant
Anaphylactoid Reaction Other Serious 8/26/2005 Female 88 lb 4/11/2006 Physician Japan
Primary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/29/2005 Female 5/12/2006 Physician Japan
Primary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 5/17/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Other Serious 3/14/2005 Male 121 lb 5/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 6/1/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/26/2006 Female 123 lb 6/6/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/12/2005 Female 112 lb 6/12/2006 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 10/29/2005 Female 6/15/2006 Physician Japan
Primary
Concomitant
Tracheal Haemorrhage Life Threatening 1/29/2004 70 Male 144 lb 6/30/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 12/17/2003 Female 117 lb 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 6/23/2006 Female 82 lb 8/28/2006 Physician Japan
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 9/6/2006 Physician Japan
Primary
Secondary
Concomitant
Thalamic Infarction Hospitalization 11/29/2005 53 Female 159 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/12/2006 Male 121 lb 9/18/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 11/14/2005 Female 88 lb 9/21/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/23/2006 Female 82 lb 9/27/2006 Physician Japan
Primary
Secondary
Concomitant
Spondylitis Hospitalization 12/30/2005 Male 9/28/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/26/2006 Female 123 lb 10/3/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 10/11/2006 Physician Japan
Primary
Secondary
Concomitant
Spondylitis Hospitalization 12/30/2005 Male 10/12/2006 Physician Japan
Primary
Secondary
Concomitant
Spondylitis Hospitalization 12/30/2005 Male 10/31/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 6/22/2005 Female 163 lb 11/7/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 11/14/2005 Female 88 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 1/23/2004 Female 119 lb 12/14/2006 Physician Japan
Primary
Secondary
Concomitant
Stenotrophomonas Infection Hospitalization 9/30/2006 Female 154 lb 12/21/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/22/2006 Female 1/4/2007 Physician Japan
Primary
Secondary
Concomitant
Haematochezia Hospitalization 6/19/2006 Female 104 lb 1/22/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/16/2007 Female 90 lb 2/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/12/2005 Female 112 lb 2/7/2007 Physician Japan
Primary
Concomitant
Osteoarthritis Other Serious 62 Female 110 lb 2/14/2007 Other Health Professional United States
Primary
Secondary
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/16/2007 Female 90 lb 2/27/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/22/2006 Female 110 lb 3/2/2007 Physician Japan
Primary
Secondary
Concomitant
Skin Disorder Other Serious 62 Female 110 lb 3/2/2007 Other Health Professional United States
Primary
Secondary
Liver Disorder Hospitalization 11/24/2006 Female 126 lb 3/8/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/19/2007 Male 3/22/2007 Physician Japan
Primary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 4/12/2007 Physician Japan
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 3/30/2007 Female 117 lb 4/16/2007 Physician Japan
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 2/16/2007 Female 104 lb 4/17/2007 Physician Japan
Primary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 4/18/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 11/18/2005 11 Male 93 lb 4/20/2007 Physician Japan
Primary
Concomitant
Sepsis Other Serious 1/27/2006 8 Male 46 lb 4/20/2007 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 45 Male 143 lb 4/13/2007 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/11/2006 10 Female 68 lb 5/1/2007 Consumer United States
Primary
Secondary
Upper Respiratory Tract Inflammation Hospitalization 1/23/2004 Female 119 lb 5/1/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 1/1/2007 Female 132 lb 5/7/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 1/1/2007 Female 132 lb 5/14/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 5/16/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/11/2006 10 Female 68 lb 5/16/2007 Consumer United States
Primary
Secondary
Stomatitis Other Serious 10/22/2003 Male 110 lb 5/25/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 3/30/2007 Female 117 lb 5/25/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 6/18/2007 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 11/1/2005 Female 99 lb 6/19/2007 Physician Japan
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 3/30/2007 Female 117 lb 6/21/2007 Physician Japan
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/5/2004 Female 121 lb 6/21/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 6/21/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/4/2006 Female 141 lb 6/26/2007 Physician Japan
Primary
Concomitant
Azoospermia Disability 1/15/2002 21 Male 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 11/1/2005 Female 99 lb 7/5/2007 Physician Japan
Primary
Secondary
Concomitant
Azoospermia Disability 1/15/2002 21 Male 7/5/2007 Consumer United States
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 7/30/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/9/2007 Female 132 lb 8/7/2007 Physician Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 12/18/2006 20 Male 115 lb 8/2/2007 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization 9/29/2006 Male 141 lb 8/16/2007 Physician Japan
Primary
Secondary
Concomitant
Trigeminal Neuralgia Hospitalization 2/26/2007 Female 8/22/2007 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 12/20/2006 Female 84 lb 8/31/2007 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 10/2/2006 45 Male 143 lb 8/31/2007 Physician Japan
Primary
Concomitant
Melaena Other Serious 3/2/2007 43 Male 132 lb 9/17/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/9/2007 Female 132 lb 9/18/2007 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/20/2006 Female 84 lb 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Carcinoma Other Serious 4/3/2007 61 Male 148 lb 10/11/2007 Physician Japan
Primary
Concomitant
Leukoencephalopathy Other Serious Female 124 lb 10/15/2007 Physician Japan
Primary
Secondary
Haematochezia Hospitalization 6/19/2006 Female 110 lb 10/17/2007 Physician Japan
Primary
Concomitant
Oedema Other Serious 2/21/2005 Male 137 lb 10/18/2007 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 6/29/2006 2 Male 10/18/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 9/24/2007 44 Female 108 lb 11/5/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 3/20/2007 64 Female 11/12/2007 Physician Japan
Primary
Secondary
Oesophageal Carcinoma Other Serious 4/3/2007 Male 148 lb 11/13/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 11/13/2007 Consumer Japan
Primary
Secondary
Concomitant
Haematochezia Hospitalization 6/19/2006 Female 110 lb 11/15/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 11/16/2007 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 11/16/2007 Consumer Japan
Primary
Secondary
Concomitant
Palatal Disorder Hospitalization 12/1/2006 68 Female 11/26/2007 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 6/29/2006 2 Male 12/7/2007 Consumer United States
Primary
Secondary
Concomitant
Eczema Other Serious 7/29/2007 Male 159 lb 12/7/2007 Physician Japan
Primary
Secondary
Concomitant
Palatal Disorder Other Serious 2/1/2007 68 Female 12/7/2007 Physician Japan
Primary
Concomitant
Palatal Disorder Other Serious 2/1/2007 68 Female 12/12/2007 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 3/28/2007 29 Male 163 lb 12/14/2007 Physician Japan
Primary
Concomitant
Peritoneal Perforation Hospitalization 7/29/2007 Male 159 lb 12/21/2007 Physician Japan
Primary
Secondary
Concomitant
Palatal Disorder Other Serious 2/1/2007 68 Female 12/21/2007 Physician Japan
Primary
Concomitant
Petechiae Hospitalization 8/9/2007 Male 159 lb 1/7/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 1/8/2008 Consumer Japan
Primary
Secondary
Concomitant
Metastases To Skin Life Threatening 12/18/2006 20 Male 115 lb 1/4/2008 Physician Japan
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 1/22/2008 Physician Japan
Primary
Concomitant
Osteitis Other Serious 1/8/2008 Female 1/25/2008 Physician Japan
Primary
Concomitant
Oral Pustule 1/8/2008 Female 1/29/2008 Physician Japan
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 2/11/2008 Physician Japan
Primary
Concomitant
Petechiae Hospitalization 1/1/2007 Male 159 lb 2/15/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 7/17/2007 65 Male 161 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Petechiae Hospitalization 3/1/2007 Male 159 lb 3/4/2008 Physician Japan
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 2/5/2007 Male 159 lb 3/28/2008 Physician Japan
Primary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 3/18/2008 Female 79 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Hospitalization 8/12/2004 Male 123 lb 4/10/2008 Physician Japan
Primary
Concomitant
Malaise Hospitalization 3/24/2008 Female 4/10/2008 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 4/11/2005 Female 112 lb 4/11/2008 Physician Japan
Primary
Secondary
Concomitant
Malaise Other Serious 3/23/2008 Female 5/8/2008 Physician Japan
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 12 Male 5/12/2008 Consumer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 5/2/2008 71 Female 5/19/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 7/17/2007 65 Male 161 lb 5/20/2008 Physician Japan
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 3/18/2008 Female 79 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Inflammation Other Serious 3/6/2007 Female 139 lb 6/6/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 4/22/2008 Female 75 lb 6/12/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/16/2007 Male 163 lb 6/20/2008 Physician Japan
Primary
Concomitant
Rectal Cancer Other Serious 2/5/2007 Male 159 lb 6/20/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 5/16/2006 Female 121 lb 6/23/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 3/18/2008 Female 79 lb 6/24/2008 Physician Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Hospitalization 8/12/2004 Male 123 lb 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/16/2006 Female 121 lb 7/8/2008 Japan
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/26/2006 Female 117 lb 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 12/13/2003 Female 110 lb 7/14/2008 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 2/1/2006 Female 117 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Wound Treatment Hospitalization 1/26/2006 Female 117 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 2/1/2006 Female 117 lb 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Inflammation Other Serious 3/6/2007 Female 139 lb 8/18/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 10/22/2007 64 Male 8/27/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Shock Other Serious 7/28/2008 Female 93 lb 9/5/2008 Physician Japan
Primary
Concomitant
Inflammation 3/6/2007 Female 139 lb 10/24/2008 Physician Japan
Primary
Secondary
Concomitant
Skin Bacterial Infection Hospitalization 8/24/2007 Female 126 lb 10/28/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/9/2007 Female 132 lb 11/5/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/12/2008 110 lb 12/8/2008 Other Health Professional Japan
Primary
Concomitant

Drug Data