Crestor combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Asthma Hospitalization 4/1/2005 Female 2/6/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 2/9/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 1/1/2000 78 Female 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/30/2003 77 Female 134 lb 4/11/2006 Physician United States
Primary
Concomitant
Respiratory Distress Hospitalization 1/1/2000 78 Female 150 lb 5/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/24/2006 52 Female 7/6/2006 Other Health Professional United States
Primary
Concomitant
Thrombosis Death 6/12/2006 51 Female 164 lb 7/5/2006 Other Health Professional United States
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 9/21/2006 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 45 Male 187 lb 10/2/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 10/2/2006 Other Health Professional United States
Primary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 11/6/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/7/2006 Male 12/13/2006 Other Health Professional United States
Primary
Concomitant
Stress 11/9/2004 Female 158 lb 12/18/2006 Physician United States
Primary
Concomitant
Increased Tendency To Bruise 51 Female 154 lb 12/22/2006 Consumer United States
Primary
Concomitant
Osteonecrosis Hospitalization 2/1/2006 Female 1/2/2007 Physician Ireland
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 144 lb 12/29/2006 Physician United States
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 10/22/2006 Female 220 lb 1/12/2007 Physician United States
Primary
Concomitant
Oesophageal Haemorrhage Hospitalization 7/8/2006 Female 105 lb 1/22/2007 Consumer Canada
Primary
Secondary
Concomitant
Urine Odour Abnormal Other Serious 64 Female 150 lb 6/2/2006 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 6/14/2005 Physician United States
Primary
Secondary
Thrombosis Death 6/12/2006 51 Female 164 lb 2/21/2007 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious Male 206 lb 3/22/2007 Consumer Canada
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 9/28/2004 53 Male 183 lb 11/17/2005 Physician United States
Primary
Secondary
Concomitant
Myalgia Required Intervention 8/26/2005 61 Male 11/17/2005 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious Male 206 lb 4/20/2007 Physician Canada
Primary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 5/3/2007 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 12/1/2003 Female 5/18/2007 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2000 21 Female 5/24/2007 Consumer United States
Primary
Secondary
Concomitant
Toothache Hospitalization 1/25/2005 41 Female 244 lb 6/12/2007 United States
Primary
Concomitant
Cardiac Flutter Other Serious 3/1/2003 68 Female 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Pruritic 3/4/2007 37 Male 190 lb 6/25/2007 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 12/1/2003 Female 7/10/2007 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 9/1/2006 Male 185 lb 7/19/2007 Consumer United States
Primary
Concomitant
Rash Erythematous 7/12/2006 70 Female 7/26/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/1/2003 68 Female 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Hospitalization 4/24/2007 Male 9/4/2007 Physician Finland
Primary
Concomitant
Renal Failure Acute Hospitalization 10/18/2007 Male 215 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Initial Insomnia 5/31/2007 59 Male 200 lb 11/8/2007 Consumer United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 6/11/2007 Female 281 lb 12/6/2007 Physician United States
Primary
Concomitant
Headache 3/6/2007 Female 95 lb 12/11/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 5/1/2007 Female 12/12/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 70 Female 163 lb 12/17/2007 United States
Primary
Concomitant
Urticaria 10/2/2007 65 Female 158 lb 12/17/2007 United States
Primary
Concomitant
Scleritis Other Serious 11/15/2006 Female 2/4/2008 Physician United States
Primary
Concomitant
Scleritis Other Serious 11/15/2006 Female 2/29/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/18/2007 Male 215 lb 3/14/2008 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/18/2007 Male 215 lb 3/20/2008 United States
Primary
Secondary
Concomitant
Salmonellosis Other Serious 10/18/2007 Male 215 lb 3/31/2008 United States
Primary
Secondary
Concomitant
Medication Residue 3/1/2007 5/13/2008 Consumer United States
Primary
Concomitant
Pain In Extremity 62 Male 6/23/2008 United States
Primary
Concomitant
Skin Reaction Other Serious 4/1/2008 Female 119 lb 7/2/2008 United States
Primary
Concomitant
Influenza Like Illness Other Serious 9/1/2006 62 Female 220 lb 6/27/2008 Physician United States
Primary
Concomitant
Pneumonia Other Serious 12/1/2007 72 Female 7/9/2008 Physician Australia
Primary
Concomitant
Myalgia Other Serious 6/1/2008 65 Female 140 lb 7/17/2008 Consumer United States
Primary
Concomitant
Influenza Like Illness Other Serious 9/1/2006 62 Female 220 lb 7/15/2008 United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2006 62 Female 220 lb 7/24/2008 United States
Primary
Concomitant
Pneumonia Other Serious 7/25/2008 70 Female 8/5/2008 Consumer Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2003 Male 8/12/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 136 lb 8/25/2008 United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2006 Male 300 lb 9/12/2008 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 61 Female 136 lb 9/8/2008 United States
Primary
Concomitant
Hallucination Other Serious 9/17/2008 Male 158 lb 10/1/2008 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization Female 10/22/2008 Consumer United States
Primary
Concomitant
Pleural Effusion Life Threatening 8/7/2008 Female 77 lb 10/31/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/4/2008 Physician Japan
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 61 Female 10/30/2008 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/7/2008 Physician Japan
Primary
Concomitant
Skin Plaque Other Serious 10/30/2008 Female 11/21/2008 Consumer France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/21/2008 Physician Japan
Primary
Concomitant
Mass Other Serious 12/1/2007 Female 11/24/2008 Consumer Canada
Primary
Concomitant
Polymyalgia Rheumatica Other Serious 8/1/2008 68 Male 193 lb 11/24/2008 United States
Primary
Concomitant
Pseudoporphyria Other Serious 65 Female 11/25/2008 Physician United States
Primary
Concomitant
Ventricular Extrasystoles 9/26/2008 53 Female 11/26/2008 Consumer United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 11/27/2008 Physician United States
Primary
Concomitant
Product Quality Issue Other Serious 7/1/2007 56 Male 190 lb 11/25/2008 Consumer United States
Primary
Concomitant
Weight Increased Disability Female 12/5/2008 Physician United Kingdom
Primary
Concomitant
Transaminases Increased Other Serious 10/30/2008 Female 12/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/21/2005 61 Female 12/8/2008 Physician United States
Primary
Concomitant
Secretion Discharge 6/20/2007 Female 12/11/2008 Physician United States
Primary
Concomitant
Discomfort 80 Female 137 lb 12/17/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 4/1/2008 82 Female 152 lb 12/17/2008 United States
Primary
Concomitant
Alopecia 5/1/2008 68 Female 12/17/2008 United States
Primary
Concomitant
Vomiting 1/1/2008 58 Female 140 lb 12/17/2008 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 10/22/2008 Male 12/17/2008 Pharmacist United States
Primary
Concomitant
Pain 66 Female 180 lb 12/18/2008 United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 12/19/2008 Physician United States
Primary
Concomitant
Blood Pressure Increased 71 Female 12/31/2008 Physician United States
Primary
Secondary
Concomitant
Productive Cough Hospitalization 11/1/2008 Female 2/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 2/13/2009 Other Health Professional Canada
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
Angina Pectoris Other Serious Female 220 lb 2/20/2009 Canada
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 2/23/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 2/24/2009 Other Health Professional Canada
Primary
Concomitant
Osteomyelitis Hospitalization 10/1/2008 Female 194 lb 2/24/2009 Other Health Professional Canada
Primary
Concomitant
Weight Increased Hospitalization 2/2/2009 73 Female 146 lb 2/23/2009 Physician France
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 3/13/2009 Other Health Professional Canada
Primary
Concomitant
Malaise Hospitalization 11/1/2008 Female 175 lb 3/26/2009 Canada
Primary
Secondary
Concomitant
Emphysema Hospitalization 1/26/2009 Male 3/27/2009 Belgium
Primary
Secondary
Concomitant
Urine Analysis Abnormal Other Serious 1/21/2009 Male 4/3/2009 Physician United States
Primary
Concomitant
Urine Analysis Abnormal Other Serious 1/21/2009 Male 4/10/2009 Physician United States
Primary
Concomitant
Malaise Hospitalization Male 4/17/2009 Physician Australia
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 61 Female 4/23/2009 Consumer Ireland
Primary
Concomitant
Malaise Hospitalization 11/1/2008 Female 175 lb 4/28/2009 Canada
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 4/29/2009 Other Health Professional Canada
Primary
Concomitant
Vision Blurred Disability 2/18/2009 69 Male 5/5/2009 Physician United Kingdom
Primary
Concomitant
Vision Blurred Disability 2/18/2009 69 Male 5/5/2009 Physician United Kingdom
Primary
Concomitant
Application Site Burn Other Serious 5/3/2009 59 Female 197 lb 5/13/2009 Consumer United States
Primary
Concomitant
Malaise Other Serious 11/1/2008 Female 175 lb 5/13/2009 Canada
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/26/2009 54 Male 201 lb 5/14/2009 Physician Australia
Primary
Concomitant
Syncope Life Threatening 4/1/2009 Female 132 lb 5/17/2009 Physician United States
Primary
Concomitant
Injection Site Swelling 6/30/2008 Female 160 lb 6/11/2009 Consumer United States
Primary
Concomitant
Nasal Congestion 3/17/2009 Male 190 lb 6/12/2009 United States
Primary
Concomitant
Pain 3/1/2009 Female 196 lb 6/12/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 11/1/2008 Male 180 lb 6/12/2009 Consumer United States
Primary
Concomitant
Pain 4/1/2009 Female 6/12/2009 United States
Primary
Concomitant
Lung Neoplasm Malignant Death 12/24/2007 Female 6/12/2009 Physician United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 5/15/2009 Female 154 lb 6/22/2009 Physician Netherlands
Primary
Concomitant
Emphysema Hospitalization 1/26/2009 Male 7/2/2009 Belgium
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 6/6/2009 Male 200 lb 7/8/2009 Physician Canada
Primary
Secondary
Concomitant
Emphysema Hospitalization 1/26/2009 Male 7/10/2009 Belgium
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 76 Female 180 lb 7/13/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/23/2003 56 Male 392 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Liver Injury 12/31/2007 53 Female 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Emphysema Hospitalization 1/26/2009 Male 8/6/2009 Belgium
Primary
Secondary
Concomitant
Polymyositis Other Serious 7/9/2009 Female 113 lb 8/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tinnitus Disability 7/20/2009 56 Male 165 lb 8/20/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization Male 8/21/2009 Consumer United States
Primary
Concomitant
Flushing 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Flushing 7/13/2009 Female 168 lb 8/23/2009 United States
Primary
Concomitant
Toothache Other Serious 5/1/2009 Female 187 lb 9/9/2009 Canada
Primary
Concomitant
Weight Decreased Other Serious 4/1/2003 38 Female 9/11/2009 United States
Primary
Concomitant
Throat Irritation Hospitalization 4/1/2009 Male 214 lb 9/11/2009 Consumer United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 10/9/2006 Female 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/3/2007 Male 186 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/22/2007 Male 190 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Swelling 6/30/2008 Female 160 lb 9/12/2009 Consumer United States
Primary
Concomitant
Throat Irritation Hospitalization 4/1/2009 Male 214 lb 9/14/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/24/2009 52 Male 182 lb 9/8/2009 Physician Canada
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2008 Female 155 lb 9/18/2009 Canada
Primary
Concomitant
Injection Site Pain 7/16/2009 Female 160 lb 9/19/2009 United States
Primary
Concomitant
Hepatic Enzyme Increased 1/1/2006 Male 225 lb 9/19/2009 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/1/2009 76 Female 180 lb 9/25/2009 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2009 76 Female 180 lb 10/8/2009 Consumer United States
Primary
Concomitant
Agranulocytosis Hospitalization 7/7/2009 Male 10/14/2009 Physician United Kingdom
Primary
Concomitant
Toothache Other Serious 5/1/2009 Female 187 lb 10/20/2009
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/23/2009 68 Female 226 lb 10/30/2009 Physician United States
Primary
Concomitant
Volvulus Other Serious 11/17/2009 Male 225 lb 12/1/2009 Canada
Primary
Concomitant

Drug Data