Levothyroxine Sodium combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 8/13/2000 Female 1/3/2006 Australia
Primary
Concomitant
Weight Decreased Life Threatening 6/1/2003 Female 144 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 73 Female 1/3/2006
Primary
Concomitant
Sepsis Hospitalization 77 Female 1/2/2006
Primary
Concomitant
Sepsis Hospitalization 74 Female 1/3/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 11/22/2005 Female 117 lb 1/12/2006 Czech Republic
Primary
Concomitant
Myositis Other Serious 9/1/2005 Female 1/18/2006 Belgium
Primary
Concomitant
Thrombocytopenia Hospitalization 12/24/2005 42 Female 1/18/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/1998 58 Female 196 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Vertigo Hospitalization 8/11/2005 Female 1/27/2006 Italy
Primary
Concomitant
Pancreatitis Hospitalization 1/4/2006 31 Female 128 lb 1/25/2006 Physician Mexico
Primary
Concomitant
Thrombocytopenia Hospitalization 12/24/2005 42 Female 2/2/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 2/9/2006 United Kingdom
Primary
Concomitant
Tuberculin Test Positive Other Serious 11/22/2005 Female 117 lb 2/10/2006 Czech Republic
Primary
Concomitant
Weight Increased Life Threatening 4/22/2005 Male 254 lb 2/13/2006 United States
Primary
Concomitant
Traumatic Fracture Other Serious 12/7/2005 Female 145 lb 2/16/2006 Physician United States
Primary
Concomitant
Nasopharyngitis Other Serious 5/1/2004 69 Female 2/5/2006 Other Health Professional United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 9/1/2005 Female 3/1/2006 Physician United States
Primary
Concomitant
Gastric Perforation Hospitalization 11/9/2005 Female 199 lb 3/2/2006 United States
Primary
Concomitant
Neuropathy Hospitalization 12/2/2005 Female 146 lb 3/3/2006 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 3/9/2006 Consumer Canada
Primary
Concomitant
Postoperative Infection Hospitalization 2/3/2006 Female 225 lb 3/14/2006 Consumer Canada
Primary
Concomitant
Hemiparesis Required Intervention 12/21/2005 63 Male 276 lb 3/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Other Serious 12/1/2005 Female 142 lb 3/16/2006 Consumer Canada
Primary
Secondary
Concomitant
Bone Cyst Other Serious 7/1/2005 Female 155 lb 3/17/2006 Consumer Canada
Primary
Concomitant
Thrombosis Hospitalization 6/6/2000 43 Female 205 lb 3/20/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 3/23/2006 Physician Canada
Primary
Concomitant
Cardiac Failure Congestive Other Serious Female 3/28/2006 Physician Australia
Primary
Concomitant
Tuberculin Test Positive Other Serious 11/22/2005 Female 117 lb 4/3/2006 Physician Czech Republic
Primary
Concomitant
Swelling Other Serious 3/29/2006 Female 143 lb 4/7/2006 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 8/1/2005 Female 150 lb 4/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/15/2004 71 Female 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 4/21/2006 Physician Canada
Primary
Concomitant
Skin Ulcer Hospitalization 78 Female 4/12/2006 Physician Germany
Primary
Concomitant
Thrombosis Hospitalization 6/6/2000 43 Female 205 lb 4/27/2006 Physician United States
Primary
Concomitant
Postoperative Infection Hospitalization 2/3/2006 Female 225 lb 5/3/2006 Consumer Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 5/11/2006 Physician Canada
Primary
Concomitant
Postoperative Infection Hospitalization 2/3/2006 Female 225 lb 5/12/2006 Consumer Canada
Primary
Concomitant
Foot Operation Other Serious 5/1/2006 Female 135 lb 5/16/2006 Consumer Canada
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 10/7/2005 Male 161 lb 5/18/2006 France
Primary
Concomitant
Stomach Discomfort Required Intervention 1/1/2005 40 Female 136 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Rash Macular Hospitalization 8/1/2005 72 Female 120 lb 1/25/2006 Consumer United States
Primary
Concomitant
Skin Reaction Hospitalization 4/13/2006 Female 141 lb 5/19/2006 Physician France
Primary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 5/23/2006 Consumer United Kingdom
Primary
Concomitant
Gastric Ulcer Haemorrhage Other Serious 2/26/2006 Female 220 lb 5/24/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 12/1/2005 Female 201 lb 5/24/2006 Consumer Canada
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 145 lb 5/25/2006 Physician United States
Primary
Concomitant
Rheumatoid Nodule Other Serious 7/1/2005 Female 155 lb 5/24/2006 Physician Canada
Primary
Concomitant
Pancytopenia Hospitalization 74 Female 5/19/2006
Primary
Concomitant
Sepsis Hospitalization 73 Female 5/19/2006 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 77 Female 5/19/2006 Physician United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 1/1/2006 Female 5/31/2006 Other Health Professional United States
Primary
Concomitant
Photosensitivity Reaction Other Serious 5/3/2006 88 Female 6/1/2006
Primary
Concomitant
Speech Disorder Other Serious 4/19/2005 51 Female 181 lb 5/25/2006 Physician United Kingdom
Primary
Concomitant
Lupus-like Syndrome Other Serious 41 Female 181 lb 6/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Disease Hospitalization 11/7/2002 Female 6/9/2006 Physician United States
Primary
Concomitant
Lung Neoplasm Other Serious 6/12/2006 58 Male 6/14/2006 Consumer United States
Primary
Concomitant
Cardiomyopathy Life Threatening 4/22/2005 Male 254 lb 6/16/2006 United States
Primary
Concomitant
Paraesthesia Other Serious 5/19/2006 Female 6/21/2006 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/27/2006 61 Female 165 lb 6/28/2006 Physician Argentina
Primary
Concomitant
Vomiting Hospitalization 6/21/2006 82 Male 174 lb 7/6/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Lymphopenia Hospitalization 1/1/2006 33 Female 7/12/2006 Other Health Professional Austria
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 7/6/2006 63 Female 7/19/2006 Consumer Spain
Primary
Concomitant
Wheezing Hospitalization 6/21/2006 82 Male 174 lb 7/20/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/14/2006 Pharmacist Canada
Primary
Concomitant
Weight Increased Hospitalization 12/14/2005 Female 201 lb 7/21/2006 Physician Canada
Primary
Concomitant
Visual Field Defect Other Serious Female 7/13/2006
Primary
Secondary
Concomitant
Wheezing Hospitalization 6/21/2006 82 Male 174 lb 7/28/2006 Physician United States
Primary
Concomitant
Dysgeusia 4/1/2006 62 Female 7/12/2006 Consumer United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 145 lb 8/1/2006 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 6/15/2006 Female 185 lb 8/4/2006 Physician United Kingdom
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 8/10/2006 Consumer Canada
Primary
Concomitant
Osteomyelitis Hospitalization 1/10/2006 Female 157 lb 8/14/2006 Physician United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization Female 143 lb 8/24/2006 Physician Netherlands
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/15/2006 Female 198 lb 8/28/2006 Physician Italy
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/15/2006 Female 198 lb 9/6/2006 Physician Italy
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/27/2006 61 Female 165 lb 9/8/2006 Physician Argentina
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 9/8/2006 Consumer Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Toe Deformity Other Serious 5/1/2006 Female 135 lb 9/15/2006 Physician Canada
Primary
Concomitant
Gastric Ulcer Haemorrhage Other Serious 2/26/2006 Female 220 lb 9/26/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/15/2006 Female 198 lb 9/29/2006 Physician Italy
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/4/2005 Female 10/4/2006 Physician Belgium
Primary
Concomitant
Mucosal Ulceration Other Serious 6/2/2006 66 Female 10/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Swelling Other Serious 9/1/2006 Female 163 lb 10/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Scar Other Serious 8/1/2006 Female 10/16/2006 Physician United States
Primary
Concomitant
Oesophageal Cancer Metastatic Other Serious 7/30/2006 Female 157 lb 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 11/7/2006 Consumer Canada
Primary
Concomitant
Uveitis Disability 1/15/2006 Male 141 lb 11/10/2006 Physician United Kingdom
Primary
Concomitant
Neoplasm Malignant Other Serious 10/6/2006 139 lb 11/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2003 Female 144 lb 11/17/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2006 80 Female 11/17/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/27/2006 61 Female 165 lb 11/17/2006 Physician Argentina
Primary
Concomitant
Gout Hospitalization 3/17/2006 Male 225 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Uveitis Other Serious 1/1/2006 32 Male 143 lb 11/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/15/2006 Female 198 lb 12/1/2006 Physician Italy
Primary
Concomitant
Facial Palsy Disability 1/1/2006 60 Female 12/8/2006 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 11/27/2006 21 Female 12/11/2006 Physician Spain
Primary
Concomitant
Psoriasis Death 8/17/2006 50 Female 12/4/2006 Physician Switzerland
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious Male 12/1/2006 Pharmacist United Kingdom
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 10/3/2006 Female 196 lb 12/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Syndrome Required Intervention 5/31/2006 70 Female 12/15/2006 Pharmacist United States
Primary
Concomitant
Sinusitis Death 7/1/2006 Female 12/21/2006 Consumer United States
Primary
Concomitant
Psoriasis Death 8/17/2006 50 Female 12/15/2006 Physician Switzerland
Primary
Secondary
Concomitant
Nausea 9/3/2006 66 Female 150 lb 12/22/2006 Consumer United States
Primary
Concomitant
Urine Ketone Body Present Other Serious 12/1/2005 Female 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Abortion Spontaneous Other Serious 12/2/2006 Female 145 lb 12/29/2006 Consumer Canada
Primary
Concomitant
Diabetes Mellitus Hospitalization 11/26/2006 Female 1/2/2007 Other Health Professional Spain
Primary
Concomitant
Psoriasis Death 8/17/2006 50 Female 12/22/2006 Physician Sweden
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 9/27/2006 Female 1/3/2007 Physician Germany
Primary
Concomitant
Insomnia 6/1/2006 65 Male 220 lb 10/11/2006 Consumer United States
Primary
Concomitant
Psoriasis Death 8/17/2006 50 Female 1/3/2007 Physician Switzerland
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/10/2006 Female 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Life Threatening 11/1/2006 58 Female 150 lb 1/6/2007 France
Primary
Secondary
Concomitant
Intestinal Polyp Other Serious Female 155 lb 1/9/2007 Consumer Canada
Primary
Concomitant
Cellulitis Hospitalization 6/15/2006 Female 185 lb 1/11/2007 Physician United Kingdom
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 10/3/2006 Female 1/15/2007 Physician Norway
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 11/6/2006 66 Female 152 lb 1/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oligodendroglioma Hospitalization 3/18/2005 66 Female 181 lb 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 10/1/2005 83 Female 112 lb 4/20/2006 Consumer United States
Primary
Concomitant
Nephrotic Syndrome Other Serious 1/1/2006 44 Female 141 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Joint Dislocation Other Serious 1/8/2005 Female 134 lb 1/22/2007 Consumer United Kingdom
Primary
Concomitant
Oesophageal Haemorrhage Hospitalization 7/8/2006 Female 105 lb 1/22/2007 Consumer Canada
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 1/31/2006 Female 130 lb 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Clostridial Infection Hospitalization 2/20/2006 Female 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/31/2006 Female 130 lb 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/30/2006 65 Female 1/26/2007 Consumer Brazil
Primary
Concomitant
Death Other Serious 11/20/2006 Male 243 lb 1/30/2007 Consumer United Kingdom
Primary
Concomitant
Joint Dislocation Other Serious 8/6/2003 Female 123 lb 2/1/2007 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/30/2006 65 Female 2/1/2007 Consumer Brazil
Primary
Concomitant
Endometriosis Other Serious 7/18/2006 Female 238 lb 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/1/2006 80 Female 2/7/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/30/2006 65 Female 176 lb 2/9/2007 Consumer Brazil
Primary
Concomitant
Neutropenia Other Serious 12/14/2006 60 Female 128 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/27/2006 85 Female 126 lb 1/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/11/2006 68 Female 2/9/2007 Brazil
Primary
Secondary
Concomitant
Death Death 2/8/2007 Female 2/26/2007 United States
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 10/7/2005 Male 161 lb 2/28/2007 France
Primary
Concomitant
Pneumonia Hospitalization 11/11/2006 68 Female 2/20/2007 Physician Brazil
Primary
Secondary
Concomitant
Limb Injury 1/1/2006 Female 11/21/2006 United States
Primary
Concomitant
Pancreatitis Hospitalization 11/1/2006 Male 209 lb 3/8/2007 Consumer United States
Primary
Concomitant
Tuberculosis Hospitalization 6/15/2005 181 lb 3/9/2007 Physician United Kingdom
Primary
Concomitant
Death Death 2/8/2007 Female 3/9/2007 United States
Primary
Concomitant
Tachycardia Life Threatening 1/23/2007 59 Female 150 lb 3/18/2007 Physician France
Primary
Secondary
Concomitant
Nausea Hospitalization 1/1/2007 3/19/2007 Physician Belgium
Primary
Concomitant
Respiratory Failure Other Serious 2/25/2007 Female 149 lb 3/21/2007 Other Health Professional Canada
Primary
Concomitant

Drug Data