Arava combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Mycosis Death 7/4/2005 Male 114 lb 1/3/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 12/25/2003 56 Female 101 lb 1/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 9/29/2005 43 Female 1/10/2006
Primary
Secondary
Whole Blood Transfusion Hospitalization 8/1/2005 Female 200 lb 1/12/2006 Consumer United States
Primary
Concomitant
Subarachnoid Haemorrhage Death 9/1/2005 43 Female 1/17/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 9/29/2005 43 Female 1/18/2006
Primary
Secondary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 4/29/2001 55 Female 148 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Skin Disorder Other Serious 10/22/2002 75 Female 185 lb 1/23/2006 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/4/2005 48 Female 1/17/2005 Australia
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 65 Female 141 lb 1/23/2006 Physician United States
Primary
Concomitant
Drug Toxicity Hospitalization 6/1/2005 Female 1/27/2006 Physician United States
Primary
Concomitant
Peripheral Embolism Other Serious 12/15/2004 Female 1/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Neoplasm Life Threatening 12/1/2005 Male 184 lb 1/31/2006 Physician United States
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 11/1/2003 90 Female 121 lb 1/30/2006 United States
Primary
Secondary
Concomitant
Vasospasm Other Serious 7/1/2002 42 Female 161 lb 2/6/2006 Physician United States
Primary
Concomitant
Peptostreptococcus Infection Hospitalization 10/25/2005 Female 2/9/2006 Physician United States
Primary
Concomitant
Whole Blood Transfusion Hospitalization 8/1/2005 Female 200 lb 2/10/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2005 69 Female 2/10/2006 Consumer Australia
Primary
Concomitant
Pneumonia Other Serious 1/17/2003 64 Female 2/10/2006 Physician Australia
Primary
Concomitant
Postoperative Wound Infection Other Serious Female 210 lb 2/7/2006 Physician United States
Primary
Concomitant
Hepatic Steatosis Other Serious 5/1/2005 66 Female 2/15/2006 Physician Australia
Primary
Concomitant
Deep Vein Thrombosis Other Serious 1/3/2006 Male 2/16/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2000 67 Male 154 lb 2/17/2006 Physician United States
Primary
Concomitant
Pleurisy Other Serious 12/1/2004 52 Female 2/17/2006 Consumer Australia
Primary
Concomitant
Oral Intake Reduced Other Serious 1/1/2005 61 Male 2/21/2006 Consumer New Zealand
Primary
Concomitant
Sputum Purulent Other Serious 7/5/2005 61 Female 2/21/2006 Physician Australia
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 1/1/2005 70 Female 159 lb 2/21/2006 Other Health Professional Switzerland
Primary
Concomitant
Pneumonia Other Serious 12/31/2005 83 Female 2/22/2006 Consumer Australia
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/1999 37 Female 148 lb 2/28/2006 Physician United States
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 2/1/2004 Male 2/28/2006 Physician Norway
Primary
Concomitant
Sputum Purulent Other Serious 7/5/2005 61 Female 98 lb 3/2/2006 Physician Australia
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 4/20/2000 56 Female 126 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Whole Blood Transfusion Hospitalization 8/1/2005 Female 200 lb 3/7/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 3/9/2006
Primary
Secondary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 3/6/2006 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 3/13/2006 Lawyer United States
Primary
Concomitant
Respiratory Failure Death 6/1/2004 72 Male 3/9/2006 Other Health Professional Sweden
Primary
Secondary
Disseminated Tuberculosis Hospitalization 8/14/2004 66 Female 3/15/2006 Physician Germany
Primary
Concomitant
Menorrhagia Hospitalization 10/1/2005 42 Female 3/16/2006 Consumer Australia
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 3/13/2006 3/21/2006 Physician Japan
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Rhinitis Other Serious 1/1/2005 Male 3/24/2006 Physician France
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2001 Female 159 lb 3/27/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Tracheal Injury Life Threatening 1/29/2004 70 Male 144 lb 3/27/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/1/2004 72 Male 3/21/2006 Other Health Professional Sweden
Primary
Secondary
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
False Positive Tuberculosis Test Other Serious 47 Male 205 lb 3/30/2006 Other Health Professional Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/15/2005 72 Male 4/6/2006 Consumer Australia
Primary
Concomitant
Viral Infection Other Serious 11/1/2005 63 Female 4/7/2006 Physician Australia
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Renal Infarct Other Serious 32 4/10/2006 Physician United States
Primary
Concomitant
Viral Infection Other Serious 11/1/2005 63 Female 4/10/2006 Physician Australia
Primary
Concomitant
Rhinitis Other Serious 1/1/2005 Male 4/13/2006 Physician France
Primary
Secondary
Concomitant
Syncope Hospitalization 9/18/2005 58 Male 4/13/2006 Physician Germany
Primary
Concomitant
Skin Exfoliation Other Serious 1/1/2005 Female 163 lb 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 6/7/2001 35 Male 220 lb 4/14/2006 Physician United States
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 6/12/2001 51 Male 201 lb 4/19/2006 Physician United States
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Vasospasm Other Serious 7/1/2002 42 Female 148 lb 4/20/2006 Physician United States
Primary
Concomitant
Hallucination Hospitalization 7/21/2005 76 Female 4/21/2006 Physician Switzerland
Primary
Secondary
Concomitant
Waldenstrom's Macroglobulinaemia Other Serious 2/1/2006 Female 4/21/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/23/2006 Female 4/21/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2002 52 Female 121 lb 4/24/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 4/24/2006
Primary
Secondary
Concomitant
Infection Hospitalization 7/21/2005 77 Female 4/25/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Wound Hospitalization 1/1/2006 59 Female 4/25/2006 Physician France
Primary
Secondary
Pulmonary Embolism Hospitalization 12/15/2005 72 Male 4/25/2006 Physician Australia
Primary
Concomitant
Menorrhagia Hospitalization 10/1/2005 42 Female 4/25/2006 Physician Australia
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/15/2005 72 Male 4/25/2006 Physician Australia
Primary
Concomitant
Weight Decreased Hospitalization 7/21/2005 76 Female 4/26/2006 Physician Switzerland
Primary
Secondary
Concomitant
Skin Neoplasm Excision Other Serious 2/1/2006 76 Female 159 lb 4/27/2006 Physician Germany
Primary
Secondary
Wrist Fracture Hospitalization 4/20/2000 56 Female 126 lb 5/1/2006 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/7/2001 35 Male 220 lb 5/2/2006 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 7/21/2005 33 Male 227 lb 5/2/2006 Physician Germany
Primary
Concomitant
Infection Hospitalization 7/21/2005 77 Female 4/26/2006 Switzerland
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5/3/2006 Physician Slovenia
Primary
Secondary
Sarcoma Other Serious 12/1/2005 45 Female 5/3/2006 Pharmacist Canada
Primary
Concomitant
Colitis Ulcerative Other Serious Male 5/5/2006 Physician Australia
Primary
Concomitant
Transaminases Increased Other Serious 5/8/2006 Physician Slovenia
Primary
Secondary
Uterine Leiomyoma Required Intervention 7/10/2000 62 Female 144 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 4/1/1997 Female 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Death 6/12/2001 51 Male 201 lb 5/10/2006 Physician United States
Primary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/10/2006 Physician Australia
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2006 Female 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/16/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/17/2006 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/23/2006 Female 5/19/2006 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 3/7/2006 37 Female 5/19/2006 Consumer Australia
Primary
Concomitant
Renal Impairment Hospitalization 56 Male 5/19/2006 Australia
Primary
Secondary
Hernia Repair Hospitalization 5/22/2001 Female 213 lb 5/19/2006 Other Health Professional United States
Primary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/19/2006 Physician Australia
Primary
Secondary
Concomitant
Transaminases Increased Life Threatening 5/11/2006 57 Female 5/22/2006 Physician Mexico
Primary
Secondary
Concomitant
Ultrasound Antenatal Screen Abnormal Other Serious 4/3/2006 32 Female 5/30/2006 Physician Mexico
Primary
Secondary
Concomitant
Yellow Skin Other Serious 4/1/1997 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 5/3/2006 88 Female 6/1/2006
Primary
Concomitant
Suicidal Ideation 6/1/2005 62 Male 150 lb 4/3/2006 Consumer United States
Primary
Concomitant
Sepsis Death 3/10/2006 60 Female 121 lb 6/7/2006 Physician Mexico
Primary
Concomitant
Pruritus Hospitalization 5/29/2006 57 Female 6/7/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Weight Decreased Life Threatening 7/1/2004 73 Female 6/5/2006 Physician Portugal
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2005 61 Female 6/20/2006 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 6/5/2006 70 Female 6/20/2006 Consumer Australia
Primary
Concomitant
Uterine Leiomyoma Required Intervention 7/10/2000 62 Female 144 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Retinal Artery Occlusion Other Serious 3/7/2006 37 Female 6/26/2006 Consumer Australia
Primary
Concomitant
Atrial Flutter Life Threatening 5/30/2006 Female 6/28/2006 Physician South Africa
Primary
Concomitant
Tracheal Haemorrhage Life Threatening 1/29/2004 70 Male 144 lb 6/30/2006 Physician Japan
Primary
Concomitant
Gastric Haemorrhage Other Serious 6/5/2006 70 Female 6/30/2006 Physician Australia
Primary
Concomitant
Pericardial Effusion Hospitalization 10/1/2005 72 Female 6/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Male 7/10/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 201 lb 7/11/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Death 5/29/2006 55 Male 246 lb 7/7/2006 Pharmacist United States
Primary
Secondary
Prostate Cancer Other Serious 12/1/2005 72 Male 7/12/2006 Physician France
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 4/25/2006 41 Female 7/14/2006 Physician Australia
Primary
Concomitant
Sarcoidosis Hospitalization 5/5/2005 51 Female 7/19/2006
Primary
Secondary
Hepatic Function Abnormal Hospitalization 3/13/2006 47 Female 104 lb 7/26/2006 Physician Japan
Primary
Concomitant
Sarcoidosis Hospitalization 5/5/2005 51 Female 7/27/2006 Other Health Professional France
Primary
Secondary
Weight Increased Other Serious 1/1/2006 66 Female 6/5/2006 United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 36 Female 7/31/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 1/28/2002 Female 145 lb 8/2/2006 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 1/1/2003 Female 8/3/2006 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 6/9/2006 Female 125 lb 8/7/2006 Physician United States
Primary
Concomitant
Viral Infection Hospitalization 11/15/2005 63 Female 8/7/2006 Physician Australia
Primary
Secondary
Concomitant
Viral Infection Hospitalization 11/15/2005 63 Female 8/10/2006 Physician Australia
Primary
Secondary
Concomitant
Rash Other Serious 6/1/2006 63 Female 8/14/2006 Consumer Australia
Primary
Concomitant
Pneumonitis Other Serious 4/13/2006 48 Female 8/14/2006 Physician New Zealand
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2003 Female 8/16/2006 Physician United States
Primary
Concomitant
Rash Hospitalization 7/17/2006 41 Male 8/23/2006 Physician United Kingdom
Primary
Concomitant
Postoperative Infection Other Serious 1/1/2003 Male 8/29/2006 Physician United States
Primary
Concomitant
Skin Lesion Other Serious 1/1/2003 Male 8/31/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/11/2006 53 Female 265 lb 9/1/2006 Consumer Australia
Primary
Concomitant
Thyroid Disorder Other Serious 6/19/2006 65 Female 170 lb 9/5/2006 Other Health Professional Canada
Primary
Concomitant
Pneumonitis Other Serious 4/13/2006 48 Female 9/7/2006 Physician New Zealand
Primary
Secondary
Concomitant
Meningitis Haemophilus Hospitalization 6/5/2006 57 Female 170 lb 9/6/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 4/13/2006 48 Female 9/13/2006 Physician New Zealand
Primary
Secondary
Concomitant
Postoperative Infection Other Serious 1/1/2003 Male 310 lb 9/14/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Male 9/19/2006 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2006 Male 163 lb 9/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 9/25/2006 Physician United States
Primary
Concomitant
Ovarian Cancer Other Serious 9/9/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/22/2006 51 Male 9/26/2006 Physician Belgium
Primary
Concomitant
Pyrexia Hospitalization 9/14/2006 49 Female 9/26/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Viral Infection Hospitalization 11/15/2005 63 Female 9/28/2006 Physician Australia
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/2006 49 Female 220 lb 10/2/2006 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 6/9/2006 Female 125 lb 10/6/2006 Physician United States
Primary
Concomitant
Malignant Melanoma Life Threatening 60 Female 10/6/2006 Physician Greece
Primary
Concomitant
Hypertriglyceridaemia Hospitalization 1/1/2006 47 Male 10/6/2006
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 1/28/2002 Female 145 lb 10/6/2006 Physician United States
Primary
Concomitant

Drug Data