Alendronate Sodium combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sciatica Disability 7/26/2005 Female 130 lb 1/4/2006 Spain
Primary
Concomitant
Breast Cancer Stage Iii Hospitalization 9/19/2005 Female 1/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Von Willebrand's Factor Multimers Abnormal Other Serious 8/1/2005 57 Female 150 lb 12/30/2005 Argentina
Primary
Concomitant
Pyrexia Other Serious 5/19/2005 Female 128 lb 1/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatomegaly Hospitalization 3/23/2005 46 Female 1/12/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/15/2005 Female 159 lb 1/18/2006 Germany
Primary
Concomitant
Metastases To Liver Other Serious 7/1/2004 Female 110 lb 1/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Vertigo Hospitalization 8/11/2005 Female 1/27/2006 Italy
Primary
Concomitant
Lumbar Spinal Stenosis Other Serious 5/19/2005 Female 119 lb 2/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/25/2003 78 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Psoriasis Other Serious 8/4/2005 Female 120 lb 2/6/2006 Canada
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Female 2/9/2006 United Kingdom
Primary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 2/9/2006 United Kingdom
Primary
Concomitant
Breast Microcalcification Other Serious 12/1/2005 Female 179 lb 2/17/2006 Consumer Canada
Primary
Concomitant
Lung Infection Hospitalization 1/29/2006 Female 2/17/2006 France
Primary
Concomitant
Nasopharyngitis Other Serious 1/1/2006 Female 117 lb 2/22/2006 Other Health Professional Denmark
Primary
Concomitant
Umbilical Hernia Other Serious 11/15/2005 Female 238 lb 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pericardial Haemorrhage Death 1/9/2006 47 Male 2/27/2006 Physician Japan
Primary
Concomitant
Monarthritis Other Serious 9/13/2005 Female 99 lb 3/7/2006 Physician Germany
Primary
Concomitant
Upper Limb Fracture Other Serious 6/6/2004 Female 132 lb 3/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Tuberculosis Hospitalization 71 Female 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 12/1/2005 Female 142 lb 3/16/2006 Consumer Canada
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 6/15/2005 Female 130 lb 3/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Condition Aggravated Disability 9/20/2005 Female 130 lb 3/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 4/23/2005 Female 207 lb 3/29/2006 Consumer United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/10/2006 61 Male 4/4/2006 Consumer United Kingdom
Primary
Concomitant
Mammogram Abnormal Other Serious 1/1/2006 46 Female 80 lb 3/28/2006 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Death 8/18/2005 Female 134 lb 4/6/2006 Physician United States
Primary
Concomitant
Colitis Ulcerative Other Serious 12/12/2003 Male 4/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Migraine Other Serious 7/7/2004 Female 152 lb 4/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/10/2006 61 Male 4/13/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 4/29/2005 73 Female 4/13/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Breast Microcalcification Other Serious 12/1/2005 Female 179 lb 4/13/2006 Physician Canada
Primary
Concomitant
Shoulder Pain Hospitalization 1/29/2006 Female 108 lb 4/14/2006 France
Primary
Concomitant
Pericardial Haemorrhage Death 1/9/2006 47 Male 4/7/2006 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/29/2005 73 Female 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 11/1/2005 80 Female 4/19/2006 Other Health Professional Sweden
Primary
Concomitant
Proteinuria Other Serious 3/1/2006 Female 134 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Bradycardia Hospitalization 3/15/2003 65 Male 154 lb 4/25/2006 Physician United States
Primary
Concomitant
Injection Site Induration Hospitalization 11/1/2005 Female 130 lb 4/25/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/29/2005 73 Female 4/18/2006 United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 6/10/2005 49 Female 217 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Gait Disturbance Disability 2/1/2006 Female 4/27/2006 Other Health Professional Ireland
Primary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 5/1/2006 Physician Brazil
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/29/2005 73 Female 4/21/2006 United Kingdom
Primary
Secondary
Concomitant
Pemphigus Hospitalization 9/28/2005 Female 88 lb 5/1/2006 Physician Austria
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sinusitis Other Serious 10/31/2004 67 Female 124 lb 3/2/2006 United States
Primary
Secondary
Concomitant
Psoriasis Other Serious 12/1/2005 Female 120 lb 5/8/2006 Consumer Canada
Primary
Concomitant
Wound Abscess Hospitalization 9/1/2005 Female 140 lb 5/12/2006 Consumer United States
Primary
Concomitant
Foot Operation Other Serious 5/1/2006 Female 135 lb 5/16/2006 Consumer Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2005 70 Female 122 lb 1/13/2006 Physician United States
Primary
Concomitant
Rash Macular Hospitalization 8/1/2005 72 Female 120 lb 1/25/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 5/23/2006 Consumer United Kingdom
Primary
Concomitant
Prostate Examination Abnormal Hospitalization Male 158 lb 5/24/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/10/2004 Female 90 lb 6/2/2006 France
Primary
Concomitant
Calculus Bladder Hospitalization 6/1/2005 Male 134 lb 6/8/2006 United Kingdom
Primary
Concomitant
Bronchiectasis Hospitalization 12/16/2005 Male 150 lb 6/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/10/2006 65 Female 6/12/2006 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/5/2006 Female 353 lb 6/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Metastatic Malignant Melanoma Other Serious 1/12/2006 Male 141 lb 6/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 5/17/2006 Female 180 lb 6/21/2006 Consumer Canada
Primary
Concomitant
Sciatica Disability 7/26/2005 Female 130 lb 6/22/2006 Spain
Primary
Concomitant
Completed Suicide Death 3/27/2006 Male 165 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Facial Palsy Other Serious Female 6/28/2006 Physician Ireland
Primary
Concomitant
Myocardial Infarction Hospitalization 56 Female 7/7/2006 Physician Greece
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Hospitalization 3/6/2006 Female 353 lb 7/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 6/2/2006 67 Female 7/14/2006 Physician Norway
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 8/1/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 10/24/2004 Female 8/3/2006 Physician Turkey
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 6/28/2006 Female 115 lb 8/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 5/15/2006 Female 119 lb 8/4/2006 Physician United Kingdom
Primary
Concomitant
Bronchiectasis Hospitalization 12/16/2005 Male 150 lb 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Hospitalization 3/6/2006 Female 353 lb 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 3/6/2006 Female 353 lb 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 100 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Hospitalization 76 Female 8/4/2006 Physician Korea, Republic Of
Primary
Secondary
Lower Respiratory Tract Infection Other Serious 12/16/2005 Male 150 lb 8/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 3/6/2006 Female 353 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 4/29/2005 73 Female 8/8/2006 Denmark
Primary
Secondary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 8/16/2006 Physician Brazil
Primary
Concomitant
Thymoma Other Serious 5/14/2006 Female 140 lb 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Salivary Gland Mass Other Serious 1/1/2006 Female 240 lb 8/25/2006 Consumer United States
Primary
Concomitant
Swelling 76 Female 8/23/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Depression Hospitalization 7/4/2006 22 Female 8/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 10/16/2003 Female 121 lb 9/1/2006 Physician United States
Primary
Concomitant
Surgery Other Serious 8/21/2006 Female 107 lb 9/1/2006 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 Female 161 lb 9/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Examination Abnormal Hospitalization Male 158 lb 9/7/2006 Physician United States
Primary
Concomitant
Rectal Perforation Other Serious 5/2/2006 Female 128 lb 9/7/2006 Physician Netherlands
Primary
Concomitant
Swelling Face Hospitalization 5/24/2006 Female 9/7/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2005 Female 180 lb 9/8/2006 Physician United States
Primary
Concomitant
Toe Deformity Other Serious 5/1/2006 Female 135 lb 9/15/2006 Physician Canada
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 1/1/2006 Female 140 lb 9/19/2006 Physician United Kingdom
Primary
Concomitant
Infection Hospitalization 8/17/2006 Female 148 lb 9/25/2006 Physician Czech Republic
Primary
Concomitant
Tendon Rupture Hospitalization 3/1/2006 Female 210 lb 10/6/2006 Consumer United States
Primary
Concomitant
Arthropathy Other Serious Female 149 lb 10/9/2006 Consumer Canada
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/7/2006 Female 10/13/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 10/19/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 38 Female 10/16/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 11/7/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Joint Effusion Other Serious 5/16/2006 Female 165 lb 11/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hemiparesis Other Serious 5/3/2006 Female 192 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2006 Female 160 lb 11/16/2006 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 10/6/2006 139 lb 11/16/2006 Consumer United States
Primary
Concomitant
Metastases To Liver Other Serious 10/13/2006 Female 117 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prurigo Hospitalization 9/1/2006 Female 121 lb 11/17/2006 Italy
Primary
Concomitant
Speech Disorder Other Serious 6/1/2006 Female 148 lb 11/17/2006 Physician Czech Republic
Primary
Concomitant
Hemiparesis Other Serious 5/3/2006 Female 192 lb 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Brain Stem Infarction Death 11/2/2006 Female 108 lb 11/20/2006 Physician Netherlands
Primary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 11/20/2006 Physician Australia
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 5/1/2006 Male 11/22/2006 United Kingdom
Primary
Concomitant
Infection Hospitalization 9/1/2006 Female 121 lb 11/28/2006 Italy
Primary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 12/1/2006 Physician Australia
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 11/14/2006 75 Female 154 lb 12/1/2006 Physician Greece
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/13/2006 Female 117 lb 12/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tibia Fracture Other Serious 11/9/2005 Female 159 lb 12/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 5/1/2006 Male 12/19/2006 United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 4/15/2006 Male 12/22/2006 United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 5/1/2006 Male 12/27/2006 Physician Netherlands
Primary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 1/3/2007 Physician Australia
Primary
Secondary
Concomitant
Arthritis Bacterial Other Serious 12/20/2006 68 Female 1/4/2007 Consumer Argentina
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/15/2006 Male 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Concomitant
Arthritis Other Serious 12/20/2006 68 Female 1/11/2007 Consumer Argentina
Primary
Secondary
Concomitant
Polyuria Other Serious 11/26/2006 82 Female 1/11/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 12/2/2006 Female 135 lb 1/12/2007 Consumer United States
Primary
Concomitant
Polyuria Other Serious 11/26/2006 82 Female 1/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/5/2006 152 lb 1/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Death 12/31/2006 Female 134 lb 1/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 11/6/2006 66 Female 152 lb 1/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Neoplasm Malignant Other Serious Female 117 lb 1/17/2007 Consumer United Kingdom
Primary
Concomitant
Nephrotic Syndrome Other Serious 1/1/2006 44 Female 141 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Erythema Multiforme Other Serious 70 Female 1/19/2007 Physician Spain
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Pharyngolaryngeal Pain Hospitalization 10/1/2006 Female 85 lb 1/19/2007 Consumer United States
Primary
Concomitant
Eczema Hospitalization 9/1/2006 Female 121 lb 1/19/2007 Italy
Primary
Concomitant
Sinusitis Other Serious 8/3/2005 Female 155 lb 1/27/2007 Physician United States
Primary
Concomitant
Pelvic Fracture Hospitalization 8/26/2006 Female 218 lb 1/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious 11/20/2006 Male 243 lb 1/30/2007 Consumer United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 5/15/2006 Female 106 lb 1/31/2007 Physician United Kingdom
Primary
Concomitant
Coeliac Disease Other Serious 1/18/2007 Female 94 lb 2/1/2007 Consumer Canada
Primary
Concomitant
Ankle Fracture Hospitalization 8/17/2004 Female 112 lb 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/6/2006 Female 212 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Colic Hospitalization 11/5/2006 Male 176 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data