Hydroxyzine combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 8/22/2005 Male 2/17/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/22/2005 Male 3/2/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/22/2005 Male 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Death Other Serious 7/27/2006 Male 146 lb 11/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor 11/30/2006 54 Female 3/13/2007 Consumer United States
Primary
Concomitant
Hepatitis Other Serious 1/1/2006 70 Male 139 lb 8/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Quadriplegia Hospitalization 4/1/2007 Female 170 lb 10/22/2007 Physician France
Primary
Concomitant
Cerebrovascular Accident Hospitalization 7/4/2007 Female 205 lb 11/30/2007 Other Health Professional United States
Primary
Concomitant
Somnolence 9/1/2007 Female 162 lb 12/13/2007 Physician United States
Primary
Concomitant
Urticaria 4/1/2007 Female 226 lb 12/14/2007 Consumer United States
Primary
Concomitant
Drug Toxicity Death 52 Male 1/11/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/21/2008 United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Dysthymic Disorder Hospitalization 6/19/2007 Male 2/22/2008 Physician France
Primary
Secondary
Concomitant
Completed Suicide Death 3/27/2008 Physician United States
Primary
Secondary
Ill-defined Disorder Other Serious 7/4/2007 Female 205 lb 6/9/2008 Other Health Professional United States
Primary
Concomitant
Visual Disturbance 1/1/2008 Male 190 lb 6/12/2008 Physician United States
Primary
Concomitant
Speech Disorder Other Serious 7/4/2007 Female 190 lb 6/13/2008 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 52 Male 6/19/2008 Physician United States
Primary
Secondary
Tuberculosis Other Serious 7/3/2002 Female 7/17/2008 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 7/17/2002 54 Male 7/30/2008 Physician United Kingdom
Primary
Concomitant
Respiratory Disorder Hospitalization 4/1/2008 11 Female 10/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 Female 10/3/2008 Physician United States
Primary
Secondary
Concomitant
Vulval Oedema 6/1/2008 Female 10/3/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vulval Oedema 6/1/2008 Female 10/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Hospitalization 4/1/2008 Female 10/24/2008 Physician United States
Primary
Secondary
Concomitant
Oesophageal Carcinoma Other Serious 3/19/2007 61 Female 10/29/2008 Other Health Professional Sweden
Primary
Concomitant
Oesophageal Carcinoma Other Serious 3/19/2007 61 Female 10/31/2008 Other Health Professional Sweden
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 2/27/2007 Female 71 lb 11/12/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 11/1/2007 Male 11/18/2008 Other Health Professional Portugal
Primary
Concomitant
Respiratory Disorder Other Serious 11/1/2007 59 Male 11/25/2008 Other Health Professional Portugal
Primary
Concomitant
Nasopharyngitis 10/21/2008 Female 182 lb 12/12/2008 United States
Primary
Concomitant
Pericarditis Hospitalization 1/1/2009 Female 3/5/2009 Other Health Professional Norway
Primary
Concomitant
Rash 1/1/2008 Female 210 lb 3/14/2009 Physician United States
Primary
Concomitant
Death Death 2/1/2009 52 Male 303 lb 4/3/2009 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/3/2009 United States
Primary
Secondary
Concomitant
Pain Death 2/1/2009 52 Male 303 lb 4/14/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/10/2009 Physician United States
Primary
Secondary
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 2/1/2009 52 Male 303 lb 4/29/2009 United States
Primary
Secondary
Rash Erythematous Hospitalization 4/1/2008 Female 71 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/16/2006 59 Female 140 lb 6/16/2009 United States
Primary
Concomitant
Migraine 3/1/2009 54 Female 6/22/2009 Consumer United States
Primary
Concomitant
Rash Erythematous Hospitalization 4/1/2008 Female 71 lb 7/1/2009 Physician United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 1/24/2007 Male 175 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 2/12/2007 Female 103 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 2/19/2007 Male 472 lb 9/11/2009 Consumer United States
Primary
Concomitant
Urticaria 4/1/2007 Female 226 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 6/6/2009 Female 163 lb 9/18/2009 Other Health Professional United States
Primary
Concomitant
Lower Limb Fracture Other Serious 11/6/2008 Female 10/8/2009 Physician Canada
Primary
Concomitant
Palpitations 6/1/2009 76 Male 113 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 Female 245 lb 12/16/2009 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 Female 212 lb 1/28/2010 Consumer United States
Primary
Concomitant
Hypoaesthesia 7/1/2009 59 Male 1/29/2010 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 11/1/2009 Female 200 lb 1/30/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/10/2010 Male 130 lb 3/9/2010 Physician France
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Myocardial Ischaemia Hospitalization 72 Male 4/19/2010 Physician Spain
Primary
Concomitant
Vomiting Other Serious 2/10/2010 34 Male 130 lb 4/19/2010 Physician France
Primary
Concomitant
Vomiting Other Serious 2/10/2010 34 Male 130 lb 4/21/2010 Physician France
Primary
Concomitant
Myocardial Ischaemia Hospitalization 72 Male 4/23/2010 Physician Spain
Primary
Concomitant
Pustular Psoriasis Hospitalization Female 269 lb 8/12/2010 Physician France
Primary
Concomitant
Optic Neuritis Other Serious 8/3/2010 67 Female 180 lb 8/24/2010 Other Health Professional United States
Primary
Concomitant
Optic Neuritis Disability 8/3/2010 67 Female 180 lb 9/4/2010 Other Health Professional United States
Primary
Concomitant
Optic Neuritis Disability 8/2/2010 67 Female 180 lb 9/29/2010 Other Health Professional United States
Primary
Concomitant
Surgery Other Serious 11/6/2008 69 Female 10/1/2010 Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2010 53 Male 11/12/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Swelling 1/4/2010 12/15/2010 Consumer United States
Primary
Concomitant
Weight Increased 4/16/2008 12/19/2010 Physician United States
Primary
Concomitant
Psoriasis Life Threatening 11/4/2010 61 Male 168 lb 12/21/2010 Physician Spain
Primary
Concomitant
Lymphadenopathy 12/23/2010 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 8/1/2010 43 Female 213 lb 1/28/2011 Consumer United States
Primary
Secondary
Concomitant
Pyrexia 1/1/2006 65 Female 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 6/7/2010 42 Female 1/29/2011 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/15/2010 44 Female 2/16/2011 Other Health Professional France
Primary
Secondary
Concomitant
Ankle Fracture Other Serious 8/1/2010 43 Female 213 lb 3/4/2011 Physician United States
Primary
Secondary
Concomitant
Burning Sensation Hospitalization Male 101 lb 3/3/2011 Other Health Professional Canada
Primary
Concomitant
Chills Other Serious 12/1/2010 3 Male 3/22/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Enthesopathy Other Serious 4/20/2010 43 Female 213 lb 4/18/2011 Physician United States
Primary
Secondary
Concomitant
Dermatitis Contact Other Serious 4/20/2010 43 Female 213 lb 4/21/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 1/17/2010 55 Male 168 lb 6/6/2011 Consumer Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/17/2010 55 Male 168 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Gallbladder Disorder Hospitalization 1/1/2000 40 Female 6/30/2011 United States
Primary
Secondary
Concomitant
Glossodynia Other Serious 7/1/2011 57 Female 155 lb 7/25/2011 Consumer United States
Primary
Concomitant
Acute Graft Versus Host Disease In Intestine Other Serious 3/19/2011 10 Male 73 lb 8/31/2011 Physician Japan
Primary
Concomitant
Gastritis Hospitalization 11/14/2010 12 Female 106 lb 9/1/2011 Physician Japan
Primary
Concomitant
Accidental Overdose Death 48 Female 247 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Abuse Death 48 Female 247 lb 9/14/2011 Physician United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious Female 9/16/2011 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 8/29/2011 41 Female 227 lb 9/27/2011 Physician United States
Primary
Concomitant
Acute Graft Versus Host Disease Hospitalization 1/16/2011 11 Male 84 lb 9/29/2011 Physician Japan
Primary
Concomitant
Diverticulitis Hospitalization 8/25/2011 41 Female 227 lb 10/3/2011 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 8/25/2011 41 Female 227 lb 10/5/2011 Physician United States
Primary
Concomitant
Hypertension Other Serious 6/12/2010 53 Male 154 lb 10/5/2011 Physician Japan
Primary
Concomitant
Sinusitis Other Serious Female 10/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Vitreous Floaters Hospitalization Female 10/20/2011 Physician United States
Primary
Secondary
Concomitant
Seasonal Allergy Hospitalization Female 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Other Serious 5/26/2009 7 Female 29 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Nasal Vestibulitis Hospitalization Female 11/16/2011 Consumer United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 7/23/2010 33 Female 11/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2011 64 Female 165 lb 11/16/2011 Physician United States
Primary
Concomitant
Hypermetabolism Hospitalization Female 11/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/2/2011 1 Male 24 lb 11/29/2011 Physician Japan
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 11/14/2010 12 Female 106 lb 11/30/2011 Physician Japan
Primary
Concomitant
Vomiting Other Serious 4/4/2009 28 Female 115 lb 11/30/2011 Physician Japan
Primary
Concomitant
Nasal Vestibulitis Hospitalization Female 12/6/2011 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 3/2/2011 12 Male 84 lb 12/9/2011 Physician Japan
Primary
Concomitant
Hypercapnia Life Threatening 6/16/2008 71 Male 230 lb 12/5/2011 Lawyer United States
Primary
Concomitant
Conjunctivitis Viral Other Serious Female 1/6/2012 Consumer United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious Female 160 lb 1/4/2012 Lawyer United States
Primary
Concomitant
Night Sweats 5/1/2011 54 Female 200 lb 1/28/2012 Consumer United States
Primary
Concomitant
Stress 3/1/2011 54 Female 210 lb 1/28/2012 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease 12/1/2008 46 Female 1/28/2012 Consumer United States
Primary
Concomitant
Blood Pressure Fluctuation Hospitalization 12/1/2003 65 Female 142 lb 1/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia 1/1/2011 58 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 1/1/2010 72 Female 1/28/2012 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 15 Male 1/27/2012 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2003 65 Female 142 lb 2/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Benign Uterine Neoplasm Other Serious 1/1/2012 51 Female 172 lb 2/29/2012 Other Health Professional United States
Primary
Concomitant
Arrhythmia Supraventricular Hospitalization 12/1/2003 65 Female 142 lb 4/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Erythema Other Serious 4/2/2012 55 Male 203 lb 4/27/2012 Pharmacist Canada
Primary
Concomitant
Osteomyelitis Other Serious 2/24/2012 11 Female 116 lb 5/2/2012 Physician United States
Primary
Concomitant
Nervousness Other Serious 1/1/2012 51 Female 172 lb 5/17/2012 Other Health Professional United States
Primary
Concomitant
Hypertension Death 2/24/2012 11 Female 116 lb 5/22/2012 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/1/2012 70 Female 140 lb 5/24/2012 Other Health Professional Canada
Primary
Concomitant
Hyperglycaemia Hospitalization 12/1/2003 65 Female 142 lb 6/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Angioedema Other Serious 5/1/2012 59 Female 160 lb 6/7/2012 Other Health Professional Canada
Primary
Concomitant
Metastases To Lymph Nodes Hospitalization Female 6/8/2012 Consumer United States
Primary
Secondary
Concomitant
Breath Sounds Abnormal Disability Female 226 lb 6/8/2012 Lawyer United States
Primary
Concomitant
Headache Hospitalization 4/30/2012 52 Male 232 lb 6/28/2012 Consumer United States
Primary
Secondary
Concomitant
Cataract Cortical Hospitalization Female 7/19/2012 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/1/2003 65 Female 142 lb 8/2/2012 Lawyer United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 8/25/2011 42 Female 227 lb 3/7/2013 Physician Us
Primary
Concomitant
Aortic Dissection Death 5/2012 Female 169 lb 10/31/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective 71 Female 127 lb 1/9/2013 Other Health Professional Us
Primary
Concomitant
Sinusitis 1/9/2012 50 Female 132 lb 10/24/2012 Physician Us
Primary
Concomitant
Renal Impairment Hospitalization 7/25/2012 55 Male 187 lb 12/3/2012 Other Health Professional Gb
Primary
Concomitant
Tooth Infection Other Serious Male 140 lb 2/7/2013 Physician Gb
Primary
Secondary
Concomitant
Cystitis Hospitalization 12/8/2012 80 Female 12/28/2012 Physician Ca
Primary
Concomitant
Knee Arthroplasty Hospitalization 11/9/2012 71 Female 143 lb 12/31/2012 Other Health Professional Ca
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/23/2008 43 Female 244 lb 1/10/2013 Physician Us
Primary
Concomitant
Renal Failure Acute Hospitalization 6/23/2012 15 Male 1/9/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Pain In Extremity 2/4/2012 49 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Onychomycosis 10/2011 55 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Throat Irritation 2/17/2012 55 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Sinus Disorder 7/4/2012 56 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Off Label Use 28 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant

Drug Data