Methotrexate combined with Ranitidine

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Hospitalization 12/24/2005 42 Female 1/6/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Skin Graft Infection Other Serious 9/15/2005 Male 192 lb 1/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Metastatic Neoplasm Other Serious 10/15/2005 Male 1/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 12/24/2005 42 Female 1/18/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Skin Graft Rejection Other Serious 9/15/2005 Male 192 lb 1/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Metastatic Neoplasm Other Serious Male 1/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 9/20/2005 Female 157 lb 1/26/2006 Physician United Kingdom
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 7/11/2000 Male 1/31/2006 Sweden
Primary
Concomitant
Pancreatitis Hospitalization 1/4/2006 31 Female 128 lb 1/25/2006 Physician Mexico
Primary
Concomitant
Thrombocytopenia Hospitalization 12/24/2005 42 Female 2/2/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/10/2005 Male 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rotator Cuff Repair Hospitalization 2/1/2001 37 Male 196 lb 2/21/2006 Physician United States
Primary
Concomitant
Metastatic Renal Cell Carcinoma Hospitalization 9/13/2005 Female 157 lb 2/22/2006 Physician United Kingdom
Primary
Concomitant
Paraesthesia Hospitalization 12/4/2005 21 Male 159 lb 2/17/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 61 Male 170 lb 2/27/2006 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 5/24/2005 64 Male 2/22/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Pituitary Tumour Benign Other Serious 12/1/2005 Female 3/13/2006 Physician Mexico
Primary
Concomitant
Pleuritic Pain Hospitalization 9/13/2005 Female 157 lb 3/22/2006 Physician United Kingdom
Primary
Concomitant
Carcinoid Tumour Of The Caecum Other Serious 10/11/2005 Female 161 lb 3/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Electrocardiogram Abnormal Other Serious 3/15/2006 Female 205 lb 3/21/2006 Other Health Professional United States
Primary
Concomitant
Oesophageal Carcinoma Other Serious Female 157 lb 3/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prolapse Repair Other Serious 6/21/2005 Female 143 lb 3/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Lung Hospitalization 2/28/2004 Female 4/7/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/29/2005 73 Female 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastric Ulcer Perforation Other Serious Female 185 lb 4/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 65 Female 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Urinary Tract Infection Other Serious 4/29/2005 73 Female 4/13/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/29/2005 73 Female 4/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/29/2005 73 Female 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/29/2005 73 Female 4/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 6/3/2002 70 Male 130 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/14/2001 Female 253 lb 4/26/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/29/2005 73 Female 4/18/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 60 Female 154 lb 4/27/2006 Physician United States
Primary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 5/1/2006 Physician Brazil
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/29/2005 73 Female 4/21/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Female 5/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Tooth Extraction Other Serious 1/1/2003 57 Male 5/9/2006 Australia
Primary
Concomitant
Vomiting Hospitalization 65 Female 5/10/2006 Consumer United Kingdom
Primary
Secondary
Vomiting Hospitalization 65 Female 5/11/2006 United Kingdom
Primary
Secondary
Vomiting Hospitalization 65 Female 5/11/2006 Consumer United Kingdom
Primary
Secondary
Pneumoperitoneum Hospitalization 65 Female 5/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Carotid Artery Occlusion Other Serious 5/14/2006 Male 156 lb 6/5/2006 Consumer United States
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 5/18/2006 Male 137 lb 6/6/2006 Physician Colombia
Primary
Concomitant
Bronchiectasis Hospitalization 12/16/2005 Male 150 lb 6/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/20/2006 Female 184 lb 6/27/2006 Pharmacist United States
Primary
Concomitant
Pneumonitis Death 10/1/2002 59 Female 6/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Death 10/18/2002 Female 7/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Therapy Non-responder Life Threatening 5/24/2005 64 Male 7/11/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/10/2005 Male 7/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 8/1/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Bronchiectasis Hospitalization 12/16/2005 Male 150 lb 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 12/16/2005 Male 150 lb 8/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Femur Fracture Other Serious 3/25/2006 Male 168 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pregnancy Other Serious 3/1/2005 Female 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/29/2005 73 Female 8/8/2006 Denmark
Primary
Secondary
Concomitant
Malignant Anorectal Neoplasm Other Serious 7/11/2005 Female 8/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 8/16/2006 Physician Brazil
Primary
Concomitant
Rectal Cancer Other Serious 7/13/2005 51 Female 8/7/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Uveitis Disability 6/24/2005 Female 126 lb 8/17/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 65 Female 8/14/2006 Other Health Professional Denmark
Primary
Concomitant
Rash Hospitalization 7/17/2006 41 Male 8/23/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 65 Female 8/22/2006 United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization 7/18/2005 65 Female 8/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Complication Other Serious 65 Female 9/7/2006 Denmark
Primary
Concomitant
Small Intestinal Perforation Required Intervention 65 Female 9/14/2006 United Kingdom
Primary
Concomitant
Pancreatic Carcinoma Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 6/8/2006 78 Female 9/27/2006 United Kingdom
Primary
Concomitant
Pericarditis Other Serious 1/6/2006 Female 96 lb 10/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neck Pain Other Serious 64 Male 201 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Neck Pain Other Serious 64 Male 201 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 10/19/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Pyelonephritis Acute Other Serious 10/23/2006 46 Female 11/1/2006 Other Health Professional Thailand
Primary
Concomitant
Pituitary Tumour Benign Other Serious 12/1/2005 Female 187 lb 11/3/2006 Physician Mexico
Primary
Concomitant
Oesophageal Cancer Metastatic Other Serious 7/30/2006 Female 157 lb 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 11/7/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 10/23/2006 46 Female 11/13/2006 Other Health Professional Thailand
Primary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 11/20/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 12/1/2006 Physician Australia
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
B-cell Lymphoma Other Serious 10/1/2005 Female 137 lb 12/13/2006 Physician United States
Primary
Concomitant
Paraesthesia 4/12/2006 Female 12/20/2006 Other Health Professional United States
Primary
Concomitant
Tendon Rupture Hospitalization 6/9/2006 Female 179 lb 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 1/3/2007 Physician Australia
Primary
Secondary
Concomitant
Peritoneal Carcinoma Other Serious 12/8/2006 Female 198 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 11/11/2006 68 Female 1/4/2007 Brazil
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Death Other Serious Male 139 lb 1/11/2007 Consumer United Kingdom
Primary
Concomitant
Somnolence Hospitalization 11/11/2006 68 Female 1/5/2007 Brazil
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 3/7/2005 Female 203 lb 1/17/2007 Consumer United Kingdom
Primary
Concomitant
Fatigue 9/1/2006 85 Female 11/7/2006 Consumer United States
Primary
Concomitant
Peritoneal Carcinoma Other Serious 11/10/2006 Female 198 lb 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Carcinoma Other Serious 10/1/2006 74 Female 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious 11/20/2006 Male 243 lb 1/30/2007 Consumer United Kingdom
Primary
Concomitant
Hepatitis B Other Serious Female 234 lb 1/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2005 64 Male 201 lb 2/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
Endometriosis Other Serious 7/18/2006 Female 238 lb 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Aortic Valve Stenosis Other Serious Male 139 lb 2/13/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/11/2006 68 Female 2/9/2007 Brazil
Primary
Secondary
Concomitant
Abdominal Wall Abscess Hospitalization 2/6/2007 56 Female 2/16/2007 Consumer Argentina
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/11/2006 68 Female 2/20/2007 Physician Brazil
Primary
Secondary
Concomitant
Cyst Other Serious 6/12/2005 Male 185 lb 3/2/2007 Consumer United Kingdom
Primary
Concomitant
Peritoneal Carcinoma Other Serious 10/1/2006 Female 198 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 12/1/2006 Female 148 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Inguinal Hernia Other Serious 7/18/2005 Male 134 lb 3/23/2007 Consumer United Kingdom
Primary
Concomitant
Sepsis Hospitalization 10/9/2006 Male 71 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Abnormal Faeces Hospitalization 10/8/2006 Female 203 lb 4/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor 12/1/2005 66 Female 132 lb 1/12/2007 Consumer United States
Primary
Concomitant
Nephrolithiasis Hospitalization 2/22/2006 Female 238 lb 4/12/2007 Consumer United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death Male 223 lb 4/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 4/2/2007 Female 190 lb 4/25/2007 Consumer Canada
Primary
Concomitant
Hypertension Death Female 126 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gait Disturbance Other Serious 4/1/2007 70 Female 220 lb 5/1/2007 Consumer United States
Primary
Concomitant
Pain Hospitalization 4/2/2007 Female 190 lb 5/2/2007 Physician Canada
Primary
Concomitant
Myocardial Infarction Other Serious 1/18/2007 Female 181 lb 5/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 243 lb 5/7/2007 Consumer United Kingdom
Primary
Concomitant
Abdominal Wall Abscess Hospitalization 2/6/2007 56 Female 5/10/2007 Consumer Argentina
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/14/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/29/2005 73 Female 5/7/2007 Germany
Primary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/17/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/25/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/9/2007 80 Female 5/29/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Female 6/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Metastatic Other Serious 6/23/2003 Female 148 lb 6/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/22/2006 Male 151 lb 6/15/2007 Physician United Kingdom
Primary
Concomitant
Tendon Rupture Hospitalization 12/1/2002 Male 178 lb 6/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Depression Hospitalization 8/19/2004 Male 130 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 12/25/2004 Female 110 lb 6/25/2007 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/7/2007 39 Male 6/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/18/2007 Female 181 lb 6/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 1/1/2007 70 Female 220 lb 6/27/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 7/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Juvenile Arthritis Hospitalization 3/2/2007 Male 45 lb 7/11/2007 Physician United Kingdom
Primary
Concomitant
Joint Dislocation Hospitalization 6/10/2006 Female 134 lb 7/12/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Smear Cervix Abnormal Other Serious 3/14/2003 Female 132 lb 7/17/2007 Consumer United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 5/7/2007 39 Male 7/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hernial Eventration Hospitalization 7/12/2007 56 Female 7/19/2007 Other Health Professional Argentina
Primary
Concomitant
Hernial Eventration Hospitalization 7/12/2007 56 Female 7/23/2007 Consumer Argentina
Primary
Concomitant
Haematuria Hospitalization 2/22/2006 Female 238 lb 7/23/2007 Consumer United Kingdom
Primary
Concomitant
Hyperplasia Hospitalization 7/18/2006 Female 238 lb 7/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iv Other Serious 11/28/2006 Female 121 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/13/2005 Male 176 lb 7/30/2007 Physician Netherlands
Primary
Concomitant
Renal Failure Other Serious 6/8/2006 78 Female 7/31/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Male 8/6/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 9/30/2006 Female 139 lb 8/7/2007 Consumer United Kingdom
Primary
Concomitant