Simvastatin



Combined with:

Aas
Asa
Ass
Yaz

Indications and Reactions:

Role Indications Reactions
Primary
Product Used For Unknown Indication 39.7%
Hypercholesterolaemia 12.7%
Blood Cholesterol Increased 11.8%
Hyperlipidaemia 8.9%
Hypertension 5.7%
Drug Use For Unknown Indication 4.2%
Blood Cholesterol 2.3%
Diabetes Mellitus 1.6%
Coronary Artery Disease 1.5%
Prophylaxis 1.5%
Atrial Fibrillation 1.3%
Myocardial Ischaemia 1.3%
Type 2 Diabetes Mellitus 1.2%
Myocardial Infarction 1.0%
Dyslipidaemia 1.0%
Schizophrenia 1.0%
Transient Ischaemic Attack 1.0%
Angina Pectoris 0.9%
Cardiovascular Event Prophylaxis 0.9%
Pain 0.9%
Rhabdomyolysis 30.2%
Myalgia 13.9%
Pain In Extremity 6.9%
Myositis 4.6%
Renal Failure Acute 4.0%
Drug Interaction 3.8%
Pain 3.6%
Tendon Rupture 3.6%
Vomiting 3.2%
Muscular Weakness 3.2%
Interstitial Lung Disease 2.9%
Weight Decreased 2.6%
Myopathy 2.5%
Muscle Spasms 2.4%
Sleep Disorder 2.3%
Nightmare 2.2%
Rash 2.2%
Liver Function Test Abnormal 2.0%
Blood Creatine Phosphokinase Increased 2.0%
Pulmonary Fibrosis 1.9%
Secondary
Product Used For Unknown Indication 29.4%
Drug Use For Unknown Indication 16.3%
Hypertension 10.4%
Blood Cholesterol Increased 7.4%
Hypercholesterolaemia 5.4%
Hyperlipidaemia 4.5%
Diabetes Mellitus 4.0%
Type 2 Diabetes Mellitus 3.8%
Depression 2.7%
Pain 1.8%
Drug Abuse 1.8%
Hepatitis C 1.7%
Coronary Artery Disease 1.7%
Asthma 1.5%
Blood Cholesterol 1.4%
Atrial Fibrillation 1.4%
Anxiety 1.3%
Acute Coronary Syndrome 1.2%
Prophylaxis 1.2%
Completed Suicide 1.1%
Rhabdomyolysis 25.1%
Myalgia 9.1%
Completed Suicide 7.3%
Weight Decreased 7.2%
Vomiting 6.8%
White Blood Cell Count Increased 5.2%
Pain In Extremity 4.0%
Renal Failure Acute 3.5%
Nausea 3.1%
Pain 3.1%
Toxic Epidermal Necrolysis 3.1%
Drug Interaction 3.0%
Weight Increased 3.0%
Rash 2.9%
Oedema Peripheral 2.6%
Death 2.4%
Renal Failure 2.3%
Liver Function Test Abnormal 2.2%
Toxicity To Various Agents 2.2%
Transaminases Increased 2.0%
Concomitant
Product Used For Unknown Indication 33.7%
Drug Use For Unknown Indication 15.4%
Hypertension 11.9%
Blood Cholesterol Increased 4.6%
Diabetes Mellitus 4.4%
Rheumatoid Arthritis 3.6%
Pain 3.1%
Depression 2.9%
Type 2 Diabetes Mellitus 2.6%
Atrial Fibrillation 2.5%
Prophylaxis 2.2%
Osteoporosis 1.7%
Hypercholesterolaemia 1.6%
Chronic Obstructive Pulmonary Disease 1.6%
Gastrooesophageal Reflux Disease 1.6%
Cardiac Disorder 1.5%
Blood Cholesterol 1.5%
Hyperlipidaemia 1.3%
Anxiety 1.1%
Blood Pressure 1.1%
Vomiting 11.4%
Weight Decreased 8.7%
Flushing 6.5%
Drug Ineffective 6.1%
Weight Increased 5.4%
Nausea 5.2%
Myocardial Infarction 5.1%
Renal Failure Acute 5.0%
Pruritus 4.7%
Syncope 4.7%
Death 4.5%
Pneumonia 4.3%
Urinary Tract Infection 4.2%
Pain 4.2%
Tremor 3.6%
Dyspnoea 3.6%
Rash 3.5%
Thrombocytopenia 3.3%
Renal Failure 3.1%
Pain In Extremity 3.1%
Interacting
Product Used For Unknown Indication 31.9%
Drug Use For Unknown Indication 12.9%
Hypertension 10.2%
Hypercholesterolaemia 4.8%
Myocardial Infarction 4.5%
Hyperlipidaemia 4.2%
Coronary Artery Disease 3.4%
Pneumonia 3.1%
Myocardial Ischaemia 2.9%
Blood Cholesterol Increased 2.6%
Supraventricular Tachycardia 2.6%
Atrial Fibrillation 2.4%
Pain 2.3%
Lower Respiratory Tract Infection 2.0%
Prophylaxis Against Transplant Rejection 2.0%
Cardiovascular Disorder 1.8%
Hypertriglyceridaemia 1.7%
Diabetes Mellitus 1.7%
Prostate Cancer 1.6%
Gastritis 1.4%
Rhabdomyolysis 31.9%
Drug Interaction 22.8%
Supraventricular Tachycardia 6.7%
Myopathy 6.0%
Myalgia 4.1%
Vomiting 4.1%
Transaminases Increased 2.8%
Blood Creatine Phosphokinase Increased 2.3%
Myositis 2.3%
Weight Decreased 2.3%
Weight Increased 1.8%
High Density Lipoprotein Decreased 1.6%
Muscular Weakness 1.6%
Myocardial Infarction 1.6%
White Blood Cell Count Increased 1.6%
Asthenia 1.3%
Gastrointestinal Haemorrhage 1.3%
International Normalised Ratio Increased 1.3%
Pain In Extremity 1.3%
Tremor 1.3%